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Article ; Online: Preliminary design for establishing compost maturity by using the spectral characteristics of five organic fertilizers.

Lin, Yi-Hong / Lin, Yong-Zhang / Lin, Yong-Hong

2022 Volume 12, Issue 1, Page(s) 15721

Abstract: The maturity of compost is involved in the availability of nutrients to crops and improvement of soil properties after fertilization. In the past, the determination of composts maturity mostly required analysis in the laboratory previously and it must ... ...

Abstract	The maturity of compost is involved in the availability of nutrients to crops and improvement of soil properties after fertilization. In the past, the determination of composts maturity mostly required analysis in the laboratory previously and it must consume a lot of time and cost. This study was conducted to use Fourier Transform Infrared (FTIR) spectroscopy and solid <sup>13</sup>C Nuclear Magnetic Resonance (<sup>13</sup>C NMR) spectroscopy to understand the mature characteristics of five type of common composts. The FTIR analysis showed that all composts contained aromatic groups. In addition, the surface of five composts contained the functional groups including hydroxyl group, carboxyl group, amino group etc. However, these functional groups changed along with maturity degree. It is recognized that the aliphatic group located at 2930 cm<sup>-1</sup> and 2850 cm<sup>-1</sup> showed a decreasing peak, and amino acid at 1385 cm<sup>-1</sup> was disappearing gradually due to the decomposition of organic matter by bacteria. There may be used to identify the maturity degree of composts. Increase of aromatic group at 1650 cm<sup>-1</sup>, carboxy (-COOH) and phenolic OH group at 1385 cm<sup>-1</sup> may prove the full maturity of composts. <sup>13</sup>C NMR analysis showed that five type of matured composts are mainly consisted with aliphatic groups and aromatic groups. The surfaces of the composts contained C-O bonds (ester, ethers, carbohydrate and other functional groups), COO<sup>-</sup> (carboxyl and ester carbons) and C=O bond (aldehydes and ketones). The strength of different absorptive characteristics of FTIR and <sup>13</sup>C NMR may be a clue to identify the maturity of composts for the design of detective instruments in the future.
MeSH term(s)	Aldehydes ; Amino Acids ; Carbohydrates ; Composting ; Esters ; Ethers ; Fertilizers ; Ketones ; Soil/chemistry
Chemical Substances	Aldehydes ; Amino Acids ; Carbohydrates ; Esters ; Ethers ; Fertilizers ; Ketones ; Soil
Language	English
Publishing date	2022-09-20
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-19714-3
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Article ; Online: Interconnection of cellular autophagy and endosomal vesicle trafficking and its role in hepatitis B virus replication and release.

Li, Jia / Lin, Yong / Wang, Xueyu / Lu, Mengji

Virologica Sinica

2024 Volume 39, Issue 1, Page(s) 24–30

Abstract: Hepatitis B virus (HBV) produces and releases various particle types, including complete virions, subviral particles with envelope proteins, and naked capsids. Recent studies demonstrate that HBV exploits distinct intracellular membrane trafficking ... ...

Abstract	Hepatitis B virus (HBV) produces and releases various particle types, including complete virions, subviral particles with envelope proteins, and naked capsids. Recent studies demonstrate that HBV exploits distinct intracellular membrane trafficking pathways, including the endosomal vesicle trafficking and autophagy pathway, to assemble and release viral and subviral particles. Herein, we summarize the findings about the distinct roles of autophagy and endosomal membrane trafficking and the interaction of both pathways in HBV replication, assembly, and release.
MeSH term(s)	Humans ; Hepatitis B virus ; Virus Assembly ; Capsid/metabolism ; Virion/metabolism ; Hepatitis B ; Virus Replication ; Autophagy
Language	English
Publishing date	2024-01-09
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	1011219-4
ISSN	1995-820X ; 1000-3223 ; 1003-5125
ISSN (online)	1995-820X
ISSN	1000-3223 ; 1003-5125
DOI	10.1016/j.virs.2024.01.001
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Article ; Online: The residual rate of HPV and the recurrence rate of CIN after LEEP with negative margins: A meta-analysis.

Lin, Yong / Long, Yan / He, Jin / Yi, Qinqin

PloS one

2024 Volume 19, Issue 3, Page(s) e0298520

Abstract: Background: HPV is detected in up to 47% of CIN and up to 70% of cervical cancers. It can cause intraepithelial neoplasia, which can eventually progress to invasive carcinoma. Almost all cervical cancers are caused by HPV. Therefore, it is especially ... ...

Abstract	Background: HPV is detected in up to 47% of CIN and up to 70% of cervical cancers. It can cause intraepithelial neoplasia, which can eventually progress to invasive carcinoma. Almost all cervical cancers are caused by HPV. Therefore, it is especially important to treat high-risk HPV. For patients who have undergone LEEP surgery, this procedure can effectively treat CIN. However, it has not been studied in a meta-analysis whether HPV remains after the surgery and whether residual HPV increases the recurrence risk of CIN. To address this gap, our study collected all relevant literature to investigate the residual rate of HPV and its potential influence on the recurrence rate of CIN. We aim to provide valuable recommendations for clinicians and patients. Methods: The Cochrane Library, EMBASE, and PubMed databases were searched from the establishment of the database until October 2023. Stata 12.0 software was used for the statistical analysis. Results: Twelve studies were included, with a total sample size of 1192 cases. The meta-analysis found that the recurrence rate of CIN was quite low [95% CI = 0.5% (0.001, 0.012); P = 0.006] when the margins were negative after LEEP and there was no residual HPV. When HPV was present, the recurrence rate of CIN was significantly higher [95% CI = 18% (0.089, 0.291), P = 0.000], even if the margins were negative. The recurrence rate of CIN with residual HPV was 3.6 times higher than the recurrence rate of CIN without residual HPV. The residual rate of HPV after LEEP with negative margins was 22.7% [95% CI (0.167, 0.294), P = 0.000], which remained relatively high. Conclusion: This meta-analysis found that the recurrence rate of CIN without residual HPV and with negative margins after LEEP was quite low, at 0.5%. However, when HPV was residual, the recurrence rate of CIN significantly increased to 18%, even if the margins were negative. The residual rate of HPV was 22.7%, even when the margins were negative after LEEP.
MeSH term(s)	Female ; Humans ; Uterine Cervical Neoplasms ; Uterine Cervical Dysplasia ; Papillomavirus Infections/epidemiology ; Papillomavirus Infections/surgery ; Neoplasm Recurrence, Local/pathology ; Margins of Excision ; Neoplasm, Residual/pathology ; Retrospective Studies ; Electrosurgery/methods
Language	English
Publishing date	2024-03-14
Publishing country	United States
Document type	Meta-Analysis ; Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0298520
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Article ; Online: Towards robust immune responses after heterologous COVID-19 vaccination and its application perspectives

Lin Yong / Huang Ailong

National Science Open, Vol

2022 Volume 1

Keywords	Science ; Q ; Engineering (General). Civil engineering (General) ; TA1-2040
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	Science Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Smoking signature as a biomarker for immunotherapy.

Li, Mengqian / Zhao, Lin-Yong

Translational lung cancer research

2022 Volume 11, Issue 1, Page(s) 122–123

Language	English
Publishing date	2022-02-15
Publishing country	China
Document type	Journal Article ; Comment
ZDB-ID	2754335-3
ISSN	2226-4477 ; 2218-6751
ISSN (online)	2226-4477
ISSN	2218-6751
DOI	10.21037/tlcr-21-966
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Article ; Online: Optimization of Vocal Singing Training Methods Using Intelligent Big Data Technology.

Lin, Yong / Mao, Kang

publication RETRACTED

Computational intelligence and neuroscience

2022 Volume 2022, Page(s) 8589517

Abstract: The development of art education and information technology has led to the importance of computer technology and multimedia technology in the development of students' independent inquiry and research skills. In the context of "Internet+," new modes of ... ...

Abstract	The development of art education and information technology has led to the importance of computer technology and multimedia technology in the development of students' independent inquiry and research skills. In the context of "Internet+," new modes of teaching phonics have emerged, reconfiguring the spatial and temporal relationship of phonics education. The use of Internet resources is not only a simple collection and sharing of educational resources, but also a new way of teaching voice, which has the magic charm of becoming one of the resources for the majority of voice enthusiasts. However, in practice, there are very few assistive software suitable for music classroom teaching. It is important to research and implement teaching aids suitable for music classroom teaching. Based on intelligent big data technology to optimize the phonetic training methods, the teaching methods are more specific, scientific, and diverse, and improve the self-learning ability and learning interest of Chinese phonetic learners. The experimental results show that the weight of the phonetic teaching optimization process is 0.154 higher than the weight before processing, which is expressed as the value of the control reliability fuzzy quantifier in this test. In other words, the reliability is "absolutely reliable." Therefore, this study is expected to promote the modernization and scientific process of Chinese vocal education and propose a new way of thinking for Chinese vocal education.
MeSH term(s)	Big Data ; Humans ; Learning ; Reproducibility of Results ; Singing ; Teaching ; Technology
Language	English
Publishing date	2022-07-09
Publishing country	United States
Document type	Journal Article ; Retracted Publication
ZDB-ID	2388208-6
ISSN	1687-5273 ; 1687-5273
ISSN (online)	1687-5273
ISSN	1687-5273
DOI	10.1155/2022/8589517
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Article ; Online: Deep Learning-Based Postoperative Recovery and Nursing of Total Hip Arthroplasty.

Wang, Hui-Min / Lin, Yong-Pei

Computational and mathematical methods in medicine

2022 Volume 2022, Page(s) 7811200

Abstract: Objective: To develop a deep learning-assisted recovery and nursing system after total hip arthroplasty and to conduct clinical trials in order to verify its accuracy.: Methods: In our study, based on manual labeling, the human hip X-ray image ... ...

Abstract	Objective: To develop a deep learning-assisted recovery and nursing system after total hip arthroplasty and to conduct clinical trials in order to verify its accuracy. Methods: In our study, based on manual labeling, the human hip X-ray image library was established, and the deep neural network based on Mask R-CNN was built. The labeled medical images were used to train the model, providing reference for nursing decision after hip replacement. A total of 80 patients with hip injury from 2016 to 2019 were selected for the study. In our paper, the patients were divided into experimental group and control group. The pertinence and effectiveness of the model for postoperative care were evaluated by comparing the hip pain (VAS index), recovery (Harris score), self-care ability (Barthel index), and postoperative complication rate between the two groups. Results: The pain and complications in the experimental group were significantly lower than those in the control group, the difference being statistically significant ( Conclusion: The application of deep learning method in the rapid nursing after total hip replacement can significantly improve the nursing ability. Compared with the traditional method, it has stronger pertinence, faster postoperative recovery, lower incidence of complications, and greatly improves the postoperative quality of life of patients with hip injury.
MeSH term(s)	Arthroplasty, Replacement, Hip/methods ; Deep Learning ; Humans ; Pain ; Postoperative Complications/etiology ; Quality of Life ; Treatment Outcome
Language	English
Publishing date	2022-05-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	2252430-7
ISSN	1748-6718 ; 1748-670X ; 1027-3662
ISSN (online)	1748-6718
ISSN	1748-670X ; 1027-3662
DOI	10.1155/2022/7811200
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Article ; Online: Prospective Application of Tannic Acid in Acetaminophen (APAP)-Induced Acute Liver Failure.

Lin, Yong-Heng / Lin, Yu-Che / Hou, Yung-Te

International journal of molecular sciences

2023 Volume 25, Issue 1

Abstract: This study investigated the effect of tannic acid (TA), a natural plant-derived polyphenol, on hepatocyte viability and function, focusing on both hepatoprotective and hepatocurative aspects within liver failure models. In an in vitro prevention model, ... ...

Abstract	This study investigated the effect of tannic acid (TA), a natural plant-derived polyphenol, on hepatocyte viability and function, focusing on both hepatoprotective and hepatocurative aspects within liver failure models. In an in vitro prevention model, the TA-containing group exhibited 1.5-fold and 59-fold higher relative cell viability and albumin synthesis, respectively, in injured mature hepatocytes (MHs) and 1.14-fold and 1.10-fold higher values in injured small hepatocytes (SHs), compared with the TA-free group. In the in vitro curative model, the TA-containing group exhibited 3.25-fold and 113-fold higher relative cell viability and albumin synthesis, respectively, in injured MHs and 0.36-fold and 3.55-fold higher values in injured SHs, compared with the TA-free group. In the in vivo disease model, the administration of 300 μL of 1 μg/mL TA significantly mitigated acute liver failure damage and post-APAP toxicity in mice. This was evident in serum analysis, where the levels of alanine transaminase, aspartate aminotransferase, and total bilirubin notably decreased, in agreement with histological observations. The study findings reveal that TA can enhance hepatic function at specific additive concentrations. Furthermore, even when injured by APAP, hepatocytes could revert to their preinjury state after additional TA supplementation. Additionally, pretreating hepatocytes with TA can alleviate subsequent damage. Thus, TA holds clinical potential in the treatment of APAP-induced liver failure.
MeSH term(s)	Animals ; Mice ; Acetaminophen/adverse effects ; Liver Failure, Acute/chemically induced ; Liver Failure, Acute/drug therapy ; Liver Failure ; Albumins ; Polyphenols
Chemical Substances	Tannic Acid ; Acetaminophen (362O9ITL9D) ; Albumins ; Polyphenols
Language	English
Publishing date	2023-12-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25010317
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Article ; Online: Treatment outcomes of tubal pregnancy with tubal preservation: A meta-analysis.

Long, Yan / Lin, Yong / He, Jin / Zhu, Rong

Medicine

2023 Volume 102, Issue 47, Page(s) e36165

Abstract: Background: Ectopic pregnancy is a common gynecological emergency that poses a significant risk of maternal mortality during the first trimester. It also increases the incidence of infertility and repeated ectopic pregnancy. The aim of this study was to ...

Abstract	Background: Ectopic pregnancy is a common gynecological emergency that poses a significant risk of maternal mortality during the first trimester. It also increases the incidence of infertility and repeated ectopic pregnancy. The aim of this study was to evaluate whether there is a difference in the degree of tubal patency between salpingostomy and systemic treatment with methotrexate (MTX), as well as the odds of intrauterine pregnancy and repeat ectopic pregnancy, and the degree of tubal patency in salpingectomy with or without tubal suturing. Methods: We searched PubMed, EMBASE, and the Cochrane Library up to April 2023. Four randomized controlled trials were included in the review. We analyzed the combined data using Review Manager 5.3 software and Stata 12.0 software, utilizing a random effects model. Results: When comparing salpingostomy and systemic treatment with MTX, there was no significant difference in the degree of tubal patency (OR = 1.09, 95% CI (0.54-2.38), P = .83). For salpingostomy with or without tubal suturing, there were no significant differences in the rates of intrauterine pregnancy, repeat ectopic pregnancy, and tubal patency degree [(OR = 1.05, 95% CI (0.41-2.68), P = .92), (OR = 0.68, 95% CI (0.19-2.42), P = .92), (OR = 1.68, 95% CI (0.14-20.33), P = .68)]. Conclusion: This meta-analysis demonstrates that systemic treatment with MTX is an effective treatment for patients who wish to preserve their fallopian tubes without undergoing surgery. This form of treatment can help avoid surgical procedures that may damage the fallopian tubes and improve fertility prospects. If choosing surgery, we believe that opting for salpingostomy without tubal suturing could reduce the operation time and minimize damage.
MeSH term(s)	Pregnancy ; Female ; Humans ; Pregnancy, Tubal/surgery ; Pregnancy, Ectopic/surgery ; Fallopian Tubes/surgery ; Salpingostomy/methods ; Methotrexate ; Treatment Outcome
Chemical Substances	Methotrexate (YL5FZ2Y5U1)
Language	English
Publishing date	2023-11-25
Publishing country	United States
Document type	Meta-Analysis ; Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000036165
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Article ; Online: Primary pulmonary angiosarcoma mimicking diffuse pulmonary hemorrhage: A case report.

Lin, Yong / Yu, Han / Wang, Changying / Zhang, Dongdong

Oncology letters

2023 Volume 25, Issue 5, Page(s) 211

Abstract: Pulmonary angiosarcomas are usually secondary tumors, and a primary angiosarcoma of the lung is extremely rare. The present study reports a case of an elderly patient diagnosed with primary pulmonary angiosarcoma (PPA). A 78-year-old man presented with a ...

Abstract	Pulmonary angiosarcomas are usually secondary tumors, and a primary angiosarcoma of the lung is extremely rare. The present study reports a case of an elderly patient diagnosed with primary pulmonary angiosarcoma (PPA). A 78-year-old man presented with a 3-month history of cough and blood in phlegm. A computed tomography scan of the chest indicated pulmonary infection with ground-glass opacity in the right upper lobe. The patient underwent lobectomy of the right upper lobe as his clinical symptoms did not significantly improve after anti-infection treatment. The postoperative pathological examination confirmed a diagnosis of PPA. He developed left lung and pelvic metastases 1 month after surgery. After four cycles of liposomal doxorubicin therapy, the patient achieved partial remission. The patient remained in sustained remission after 6 months of follow-up. The present case report is intended to provide diagnostic insight into PPA. In addition, the findings indicate that timely diagnosis and treatment of PPA are very important due to its increased risk of local recurrence and distant metastasis.
Language	English
Publishing date	2023-04-06
Publishing country	Greece
Document type	Case Reports
ZDB-ID	2573196-8
ISSN	1792-1082 ; 1792-1074
ISSN (online)	1792-1082
ISSN	1792-1074
DOI	10.3892/ol.2023.13797
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