Artikel ; Online: Anti-inflammatory effects of new human histamine H
Inflammation research : official journal of the European Histamine Research Society ... [et al.
2022 Band 72, Heft 2, Seite(n) 181–194
Abstract: Objective: Microglia play an important role in the neuroinflammation developed in response to various pathologies. In this study, we examined the anti-inflammatory effect of the new human histamine H: Material and methods: The affinity of flavonoids ( ...
| Abstract | Objective: Microglia play an important role in the neuroinflammation developed in response to various pathologies. In this study, we examined the anti-inflammatory effect of the new human histamine H Material and methods: The affinity of flavonoids (E243 -flavone and IIIa-IIIc-chalcones) for human H Results: Chalcone derivatives showed high affinity at human H Conclusions: These results emphasize the importance of further research to accurately identify the anti-inflammatory mechanism of action of chalcones. |
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| Mesh-Begriff(e) | Mice ; Humans ; Animals ; Histamine/metabolism ; Neuroinflammatory Diseases ; Flavonoids/pharmacology ; Flavonoids/therapeutic use ; Chalcones/metabolism ; Chalcones/pharmacology ; Chalcones/therapeutic use ; Microglia/metabolism ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Receptors, Histamine/metabolism ; Cytokines/metabolism ; Lipopolysaccharides/pharmacology ; Inflammation/drug therapy ; Inflammation/metabolism | |||||
| Chemische Substanzen | Histamine (820484N8I3) ; Flavonoids ; Chalcones ; Anti-Inflammatory Agents ; Receptors, Histamine ; Cytokines ; Lipopolysaccharides | |||||
| Sprache | Englisch | |||||
| Erscheinungsdatum | 2022-11-12 | |||||
| Erscheinungsland | Switzerland | |||||
| Dokumenttyp | Journal Article | |||||
| ZDB-ID | 1221794-3 | |||||
| ISSN | 1420-908X ; 1023-3830 | |||||
| ISSN (online) | 1420-908X | |||||
| ISSN | 1023-3830 | |||||
| DOI | 10.1007/s00011-022-01658-z | |||||
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| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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