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  1. Article ; Online: Explaining quantum field theory

    Lincoln, Don

    Science (New York, N.Y.)

    2024  Volume 383, Issue 6685, Page(s) 835

    Abstract: A theoretical physicist offers an intuitive primer on the nature of matter and energy. ...

    Abstract A theoretical physicist offers an intuitive primer on the nature of matter and energy.
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.adn9364
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 27: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 77: Show issues

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  2. Article: Care for the Eyes.

    Lincoln, D F

    Hall's journal of health

    2022  Volume 22, Issue 12, Page(s) 393–394

    Language English
    Publishing date 2022-12-09
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: MMDRP: drug response prediction and biomarker discovery using multi-modal deep learning.

    Taj, Farzan / Stein, Lincoln D

    Bioinformatics advances

    2024  Volume 4, Issue 1, Page(s) vbae010

    Abstract: Motivation: A major challenge in cancer care is that patients with similar demographics, tumor types, and medical histories can respond quite differently to the same drug regimens. This difference is largely explained by genetic and other molecular ... ...

    Abstract Motivation: A major challenge in cancer care is that patients with similar demographics, tumor types, and medical histories can respond quite differently to the same drug regimens. This difference is largely explained by genetic and other molecular variabilities among the patients and their cancers. Efforts in the pharmacogenomics field are underway to understand better the relationship between the genome of the patient's healthy and tumor cells and their response to therapy. To advance this goal, research groups and consortia have undertaken large-scale systematic screening of panels of drugs across multiple cancer cell lines that have been molecularly profiled by genomics, proteomics, and similar techniques. These large data drug screening sets have been applied to the problem of drug response prediction (DRP), the challenge of predicting the response of a previously untested drug/cell-line combination. Although deep learning algorithms outperform traditional methods, there are still many challenges in DRP that ultimately result in these models' low generalizability and hampers their clinical application.
    Results: In this article, we describe a novel algorithm that addresses the major shortcomings of current DRP methods by combining multiple cell line characterization data, addressing drug response data skewness, and improving chemical compound representation.
    Availability and implementation: MMDRP is implemented as an open-source, Python-based, command-line program and is available at https://github.com/LincolnSteinLab/MMDRP.
    Language English
    Publishing date 2024-01-20
    Publishing country England
    Document type Journal Article
    ISSN 2635-0041
    ISSN (online) 2635-0041
    DOI 10.1093/bioadv/vbae010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Thermal exploration in engine design.

    Carr, Lincoln D / Parigi, Valentina

    Science (New York, N.Y.)

    2023  Volume 379, Issue 6636, Page(s) 984–985

    Abstract: A negative-temperature heat engine is achieved with photons. ...

    Abstract A negative-temperature heat engine is achieved with photons.
    Language English
    Publishing date 2023-03-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.adg7317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 27: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 77: Show issues

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  5. Book: Important bird areas in Africa and associated islands

    Fishpool, Lincoln D. C.

    priority sites for conservation

    (Birdlife conservation series ; 11)

    2001  

    Author's details ed. by Lincoln D. C. Fishpool
    Series title Birdlife conservation series ; 11
    Collection
    Language English
    Size XVI, 1144 S. : Ill., graph. Darst., Kt.
    Publisher BirdLife International u.a.
    Publishing place Cambridge
    Publishing country Great Britain
    Document type Book
    Note Zsfassung in franz. Sprache
    HBZ-ID HT013265771
    ISBN 1-874357-20-X ; 978-1-874357-20-9
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    024/60 available for loan (reading room) Freihandmagazin (U1)

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  6. Article ; Online: Optimization of Infant Feeding in the Setting of Posterior Tongue Tie: A Response.

    Ghaheri, Bobak A / Lincoln, Douglas / Mai, Tuyet Nhi T / Mace, Jess C

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

    2023  Volume 169, Issue 1, Page(s) 195–196

    MeSH term(s) Infant ; Humans ; Ankyloglossia/surgery ; Tongue/surgery ; Lingual Frenum/surgery
    Language English
    Publishing date 2023-01-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1177/01945998221112321
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  7. Article ; Online: Fractional Integrable Nonlinear Soliton Equations.

    Ablowitz, Mark J / Been, Joel B / Carr, Lincoln D

    Physical review letters

    2022  Volume 128, Issue 18, Page(s) 184101

    Abstract: Nonlinear integrable equations serve as a foundation for nonlinear dynamics, and fractional equations are well known in anomalous diffusion. We connect these two fields by presenting the discovery of a new class of integrable fractional nonlinear ... ...

    Abstract Nonlinear integrable equations serve as a foundation for nonlinear dynamics, and fractional equations are well known in anomalous diffusion. We connect these two fields by presenting the discovery of a new class of integrable fractional nonlinear evolution equations describing dispersive transport in fractional media. These equations can be constructed from nonlinear integrable equations using a widely generalizable mathematical process utilizing completeness relations, dispersion relations, and inverse scattering transform techniques. As examples, this general method is used to characterize fractional extensions to two physically relevant, pervasive integrable nonlinear equations: the Korteweg-deVries and nonlinear Schrödinger equations. These equations are shown to predict superdispersive transport of nondissipative solitons in fractional media.
    Language English
    Publishing date 2022-05-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.128.184101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4' 58/153: Show issues

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  8. Article ; Online: Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower.

    Shuai, Shimin / Gallinger, Steven / Stein, Lincoln D

    Nature communications

    2022  Volume 13, Issue 1, Page(s) 7571

    Language English
    Publishing date 2022-12-08
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-022-32343-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Clinical Utility of Genomic Testing in Cancer Care.

    Pritchard, Daryl / Goodman, Clifford / Nadauld, Lincoln D

    JCO precision oncology

    2022  Volume 6, Page(s) e2100349

    Abstract: Purpose: In the era of personalized medicine, physicians rely on their understanding of clinical utility to assess the value of rapidly evolving genetic and genomic tests. Current definitions of the clinical utility of genetic testing sufficiently ... ...

    Abstract Purpose: In the era of personalized medicine, physicians rely on their understanding of clinical utility to assess the value of rapidly evolving genetic and genomic tests. Current definitions of the clinical utility of genetic testing sufficiently capture a range of benefits and risks that derive from positive and negative results of tests that assess one gene or a few genes. However, these definitions of clinical utility are inadequate to recognize the wider scope of benefits that accrue from more comprehensive genomic tests, which can develop data sets that inform clinical decision making as well as population health and scientific advancement in novel ways.
    Methods: An expert roundtable discussion with leaders from multiple sectors of the health care ecosystem was convened to develop a contemporary, fuller definition of the clinical utility of genomic testing in cancer care.
    Results: We present an updated definition and offer recommendations for successful implementation.
    Conclusion: Applying this expanded definition will encourage evidence-based use of genomic testing in cancer care by helping physicians and other health care decision makers account for the broader range of benefits and risks of testing for individual patients, health systems, population health, and scientific advancement.
    MeSH term(s) Genetic Profile ; Genetic Testing ; Humans ; Neoplasms/diagnosis ; Neoplasms/genetics ; Neoplasms/therapy
    Language English
    Publishing date 2022-03-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2473-4284
    ISSN (online) 2473-4284
    DOI 10.1200/PO.21.00349
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Fourteen quick tips for crowdsourcing geographically linked data for public health advocacy.

    Joshua Atienza / Anjalee Benedict / Lincoln D Stein / Kashif Pirzada / Cheryl White / Shraddha Pai

    PLoS Computational Biology, Vol 19, Iss 9, p e

    2023  Volume 1011285

    Abstract: This article presents 14 quick tips to build a team to crowdsource data for public health advocacy. It includes tips around team building and logistics, infrastructure setup, media and industry outreach, and project wrap-up and archival for posterity. ...

    Abstract This article presents 14 quick tips to build a team to crowdsource data for public health advocacy. It includes tips around team building and logistics, infrastructure setup, media and industry outreach, and project wrap-up and archival for posterity.
    Keywords Biology (General) ; QH301-705.5
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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