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  1. AU="Linh, N N"
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  1. Article ; Online: Potential benefits of active case finding to reduce the burden of TB.

    Linh, N N / Miller, C / Marks, G B

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2021  Volume 25, Issue 2, Page(s) 93–94

    MeSH term(s) Humans ; Mass Screening ; Tuberculosis/diagnosis ; Tuberculosis/epidemiology ; Tuberculosis/prevention & control
    Language English
    Publishing date 2021-03-03
    Publishing country France
    Document type Journal Article
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.20.0894
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Is effective patient support missing in the global response to multidrug-resistant tuberculosis?

    Cocozza, A M / Linh, N N / Jaramillo, E

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2020  Volume 24, Issue 6, Page(s) 626–630

    Abstract: Multidrug-resistant tuberculosis (MDR-TB) is a threat to the achievement of the global targets to the World Health Organization (WHO) End TB by 2030 Strategy. The WHO consolidated guidelines for the treatment of drug-resistant TB emphasise the importance ...

    Abstract Multidrug-resistant tuberculosis (MDR-TB) is a threat to the achievement of the global targets to the World Health Organization (WHO) End TB by 2030 Strategy. The WHO consolidated guidelines for the treatment of drug-resistant TB emphasise the importance of addressing health systems issues, including supporting patients during treatment, contributing to improved adherence, reduced catastrophic costs and better treatment outcomes. The recently published results of the STREAM (Standardised Treatment Regimen of Anti-TB Drugs for Patients with MDR-TB) clinical trial and the Delamanid 213 Trial suggest that the implementation of a proper patient-centred approach to the clinical and programmatic management of MDR-TB as per the WHO guidelines is key to improving treatment outcomes in MDR-TB patients.
    MeSH term(s) Antitubercular Agents/therapeutic use ; Humans ; Treatment Outcome ; Tuberculosis, Multidrug-Resistant/drug therapy ; Tuberculosis, Multidrug-Resistant/epidemiology ; World Health Organization
    Chemical Substances Antitubercular Agents
    Language English
    Publishing date 2020-06-18
    Publishing country France
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.19.0529
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: No universal access to drug-resistant tuberculosis care without engaging all health care providers.

    Linh, N N / Wares, F / Cocozza, A M / Uplekar, M / Raviglione, M

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2020  Volume 24, Issue 1, Page(s) 118–123

    Abstract: Should the engagement of all health care providers in all aspects of programmatic management of drug-resistant tuberculosis (PMDT) become a priority in the national strategic plans for tuberculosis (TB), progress towards universal access to diagnosis, ... ...

    Abstract Should the engagement of all health care providers in all aspects of programmatic management of drug-resistant tuberculosis (PMDT) become a priority in the national strategic plans for tuberculosis (TB), progress towards universal access to diagnosis, treatment and care of drug-resistant tuberculosis (DR-TB) would accelerate. This would be especially crucial in countries where the private sector is a significant provider of health services. Proven successful interventions to engage all health care providers and partners in the cascade of prevention, diagnosis, treatment and care of DR-TB patients need to be urgently scaled up. Such engagement should not be limited to the diagnosis and treatment of DR-TB, but extended also to all the aspects of PMDT, including approaches ensuring that patient-centred care, social support, pharmacovigilance and surveillance. Integral to the End TB Strategy, PMDT should be embedded in all public-private mix initiatives for TB and vice versa.
    MeSH term(s) Health Personnel ; Humans ; Private Sector ; Tuberculosis ; Tuberculosis, Multidrug-Resistant/diagnosis ; Tuberculosis, Multidrug-Resistant/drug therapy
    Language English
    Publishing date 2020-01-31
    Publishing country France
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.19.0436
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Cortical oxygen extraction fraction using quantitative BOLD MRI and cerebral blood flow during vasodilation.

    Le, Linh N N / Wheeler, Gregory J / Holy, Emily N / Donnay, Corinne A / Blockley, Nicholas P / Yee, Alan H / Ng, Kwan L / Fan, Audrey P

    Frontiers in physiology

    2023  Volume 14, Page(s) 1231793

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-10-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2023.1231793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: An assessment of current tuberculosis patient care and support policies in high-burden countries.

    Cocozza, A M / Linh, N N / Nathavitharana, R R / Ahmad, U / Jaramillo, E / Gargioni, G E M / Fox, G J

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2020  Volume 24, Issue 1, Page(s) 36–42

    Abstract: CONTEXT: ...

    Abstract CONTEXT:
    MeSH term(s) Cross-Sectional Studies ; Humans ; Patient Care ; Policy ; Tuberculosis/diagnosis ; Tuberculosis/epidemiology ; Tuberculosis/therapy ; World Health Organization
    Language English
    Publishing date 2020-01-31
    Publishing country France
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.19.0183
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The trend of tuberculosis cases over 60 years in Fiji's largest treatment centre: 1950-2010.

    Tamani, T / Bissell, K / Tayler-Smith, K / Gounder, S / Linh, N N / Graham, S M

    Public health action

    2015  Volume 4, Issue 1, Page(s) 42–46

    Abstract: Setting: P J Twomey Hospital, National Tuberculosis Programme, Fiji.: Objectives: To review the trend in numbers of tuberculosis (TB) cases registered each year from 1950 to 2010 at P J Twomey Hospital, Fiji's largest TB treatment centre and central ... ...

    Abstract Setting: P J Twomey Hospital, National Tuberculosis Programme, Fiji.
    Objectives: To review the trend in numbers of tuberculosis (TB) cases registered each year from 1950 to 2010 at P J Twomey Hospital, Fiji's largest TB treatment centre and central TB unit, and to consider trends in the context of key TB control events in Fiji.
    Design: Descriptive study of data from medical records and TB registers, including age, sex, ethnicity, TB diagnosis and smear result.
    Results: Between 1950 and 2010, 14 616 cases were registered at P J Twomey Hospital. Of these, 58% were male, 70% were indigenous Fijians (i-taukei) and 64% were aged 15-49 years. The caseload dropped sharply in the 1960s, and has fallen steadily since 1990. Smear results were available for the majority of cases (91%). Between 1950 and 1985, smear-positive cases accounted for 19% of cases overall; this increased to 41% after 1985 following laboratory training. The numbers of sputum smear-positive cases recorded each year has been increasing in the last decade.
    Conclusion: There have been marked changes in TB caseload over the last 60 years at Fiji's largest TB treatment centre. The recent increase in smear-positive cases while total TB cases have been falling needs further evaluation.
    Language English
    Publishing date 2015-09-30
    Publishing country France
    Document type Journal Article
    ISSN 2220-8372
    ISSN 2220-8372
    DOI 10.5588/pha.13.0100
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Nurses graduating in Fiji between 2001 and 2010: sufficient supply for Fiji's health service demands?

    Aiyub, S / Linh, N N / Tayler-Smith, K / Khogali, M / Bissell, K

    Public health action

    2013  Volume 3, Issue 1, Page(s) 63–67

    Abstract: Setting: Fiji's schools of nursing and government health services, 2001-2010.: Objectives: To report on 1) the number and characteristics of nurses who graduated in Fiji, 2) the proportion of vacant nursing positions in the government health services ...

    Abstract Setting: Fiji's schools of nursing and government health services, 2001-2010.
    Objectives: To report on 1) the number and characteristics of nurses who graduated in Fiji, 2) the proportion of vacant nursing positions in the government health services and 3) attrition among nurses.
    Design: Descriptive study involving a retrospective record review of Ministry of Health annual reports and nursing registers.
    Results: Over the period 2001-2010, a total of 1500 nurses graduated, with the overall trend being a gradual increase in newly qualified nurses year on year. Available data from 2007 onwards showed relatively low vacancy rates (range 0.4-2%), with a sharp rise to 15% in 2009. Complete data on nurse attrition were available only from 2007 onwards, with rates of attrition ranging from 4% to 10%; the most common reason for attrition was resignation.
    Conclusion: While it was unable to directly assess whether Fiji's supply of nursing graduates has been meeting the country's health service demands, this study provides a series of baseline data on Fiji's nurse graduate and nursing workforce. In addition, it identifies some of the challenges and gaps that need to be considered to better assess and address nursing staff shortages.
    Language English
    Publishing date 2013-03-04
    Publishing country France
    Document type Journal Article
    ISSN 2220-8372
    ISSN 2220-8372
    DOI 10.5588/pha.12.0067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Radiographic predictors of subsequent reactivation of tuberculosis.

    Linh, N N / Marks, G B / Crawford, A B H

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2007  Volume 11, Issue 10, Page(s) 1136–1142

    Abstract: Setting: A cohort of migrants to Australia (n = 7265) selected to be at increased risk of tuberculosis (TB) were assessed at the Liverpool Chest Clinic, Sydney, between 1984 and 2003.: Objective: To assess the reproducibility and predictive value of ... ...

    Abstract Setting: A cohort of migrants to Australia (n = 7265) selected to be at increased risk of tuberculosis (TB) were assessed at the Liverpool Chest Clinic, Sydney, between 1984 and 2003.
    Objective: To assess the reproducibility and predictive value of various radiographic criteria for predicting the subsequent development of TB.
    Methods: A nested case control study was conducted. Cases were those who had a confirmed diagnosis of TB during follow-up (n = 60). A random sample of 107 controls was selected. Initial chest X-rays were read independently and blinded to case vs. control status by two readers according to two classification systems. Agreement was quantified as weighted kappa (kappaw). Sensitivity and specificity for subsequent TB were estimated.
    Results: There was moderate agreement between readers for both classification systems (kappaw 0.67 and 0.60, respectively). The presence of calcified nodular densities or fibrosis together with non-calcified nodular densities in mid and/or upper lung zones or the presence of a pulmonary infiltrate typical of TB had a sensitivity of 66% for subsequent pulmonary TB and a specificity of 82%. Minor abnormalities or findings consistent with past primary TB infection alone were not predictive of subsequent TB.
    Conclusions: Radiographic screening can be helpful in identifying individuals at increased risk of subsequent TB.
    MeSH term(s) Adult ; Aged ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Mycobacterium tuberculosis/isolation & purification ; New South Wales/epidemiology ; Odds Ratio ; Prognosis ; Radiography, Thoracic/methods ; Recurrence ; Retrospective Studies ; Sensitivity and Specificity ; Time Factors ; Tuberculosis, Pulmonary/diagnostic imaging ; Tuberculosis, Pulmonary/epidemiology ; Tuberculosis, Pulmonary/microbiology
    Language English
    Publishing date 2007-10
    Publishing country France
    Document type Journal Article
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: The trend of tuberculosis cases over 60 years in Fiji's largest treatment centre

    Tayler-Smith, K / Linh, N N / Bissell, K / Tamani, T / Graham, S M / Gounder, S

    1950-2010

    2014  

    Abstract: Journal Article ... SETTING: P J Twomey Hospital, National Tuberculosis Programme, Fiji. OBJECTIVES: To review the trend in numbers of tuberculosis (TB) cases registered each year from 1950 to 2010 at P J Twomey Hospital, Fiji's largest TB treatment centre ...

    Abstract Journal Article

    SETTING: P J Twomey Hospital, National Tuberculosis Programme, Fiji. OBJECTIVES: To review the trend in numbers of tuberculosis (TB) cases registered each year from 1950 to 2010 at P J Twomey Hospital, Fiji's largest TB treatment centre and central TB unit, and to consider trends in the context of key TB control events in Fiji. DESIGN: Descriptive study of data from medical records and TB registers, including age, sex, ethnicity, TB diagnosis and smear result. RESULTS: Between 1950 and 2010, 14 616 cases were registered at P J Twomey Hospital. Of these, 58% were male, 70% were indigenous Fijians (i-taukei) and 64% were aged 15-49 years. The caseload dropped sharply in the 1960s, and has fallen steadily since 1990. Smear results were available for the majority of cases (91%). Between 1950 and 1985, smear-positive cases accounted for 19% of cases overall; this increased to 41% after 1985 following laboratory training. The numbers of sputum smear-positive cases recorded each year has been increasing in the last decade. CONCLUSION: There have been marked changes in TB caseload over the last 60 years at Fiji's largest TB treatment centre. The recent increase in smear-positive cases while total TB cases have been falling needs further evaluation.
    Language English
    Publishing date 2014-03-01
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Book ; Online: Nurses graduating in Fiji between 2001 and 2010

    Khogali, M / Tayler-Smith, K / Linh, N N / Aiyub, S / Bissell, K

    sufficient supply for Fiji's health service demands?

    2013  

    Abstract: Journal Article ... SETTING: Fiji's schools of nursing and government health services, 2001-2010. OBJECTIVES: To report on 1) the number and characteristics of nurses who graduated in Fiji, 2) the proportion of vacant nursing positions in the government ... ...

    Abstract Journal Article

    SETTING: Fiji's schools of nursing and government health services, 2001-2010. OBJECTIVES: To report on 1) the number and characteristics of nurses who graduated in Fiji, 2) the proportion of vacant nursing positions in the government health services and 3) attrition among nurses. DESIGN: Descriptive study involving a retrospective record review of Ministry of Health annual reports and nursing registers. RESULTS: Over the period 2001-2010, a total of 1500 nurses graduated, with the overall trend being a gradual increase in newly qualified nurses year on year. Available data from 2007 onwards showed relatively low vacancy rates (range 0.4-2%), with a sharp rise to 15% in 2009. Complete data on nurse attrition were available only from 2007 onwards, with rates of attrition ranging from 4% to 10%; the most common reason for attrition was resignation. CONCLUSION: While it was unable to directly assess whether Fiji's supply of nursing graduates has been meeting the country's health service demands, this study provides a series of baseline data on Fiji's nurse graduate and nursing workforce. In addition, it identifies some of the challenges and gaps that need to be considered to better assess and address nursing staff shortages.
    Language English
    Publishing date 2013-03-01
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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