LIVIVO - Suchergebnisse -

Suchergebnis

Treffer 1 - 10 von insgesamt 35

Suchoptionen

Artikel: Editorial: Antipsychotics of New Generation: Where Are We now?

Lipina, Tatiana V / O'Tuathaigh, Colm / Li, Shupeng

2021 Band 12, Seite(n) 646286

Sprache	Englisch
Erscheinungsdatum	2021-02-22
Erscheinungsland	Switzerland
Dokumenttyp	Editorial
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2021.646286
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Über subito bestellen

Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

Details ▾
- Kostenpflichtig bestellen

Buch: Drug discovery for schizophrenia

Lipina, Tatiana V / Roder, John C

(RSC drug discovery series, ; no. 44)

2015

Körperschaft	Royal Society of Chemistry (Great Britain),
Verfasserangabe	edited by Tatiana V. Lipina, John C. Roder
Serientitel	RSC drug discovery series, ; no. 44
Mesh-Begriff(e)	Schizophrenia/drug therapy ; Drug Discovery ; Antipsychotic Agents
Sprache	Englisch
Umfang	xiv, 289 pages :, illustrations
Dokumenttyp	Buch
ISBN	9781782620266 ; 9781782622499 ; 1782620265 ; 1782622497
Datenquelle	Katalog der US National Library of Medicine (NLM)

Zusatzmaterialien

Über subito bestellen

Fernleihe an ZB MED

Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Details ▾
- Kostenpflichtig bestellen

Artikel ; Online: Lack of synaptic protein, calsyntenin-2, impairs morphology of synaptic complexes in mice.

Ranneva, Svetlana V / Maksimov, Valeriy F / Korostyshevskaja, Irina M / Lipina, Tatiana V

Synapse (New York, N.Y.)

2019 Band 74, Heft 2, Seite(n) e22132

Abstract: Calsyntenin-2 (Clstn2) is the synaptic protein, which belongs to the superfamily of cadherins, playing an important role in learning and memory. We recently reported that Clstn2 knockout mice (Clstn2-KO) have a deficit of GABAergic interneurons, ... ...

Abstract	Calsyntenin-2 (Clstn2) is the synaptic protein, which belongs to the superfamily of cadherins, playing an important role in learning and memory. We recently reported that Clstn2 knockout mice (Clstn2-KO) have a deficit of GABAergic interneurons, associated with hyperactivity, deficient spatial memory, and social behavior. Therefore, we sought to characterize morphometric features of the ultrastructure of synaptic complexes of hippocampal and cortical neurons in Clstn2-KO mice, using high magnification electron microscopy. Morphometric analysis revealed a reduction of symmetric (inhibitory) synaptic density, length of synaptic contacts, and postsynaptic density in neurons of Clstn2-KO mice. Moreover, cortical neurons of Clstn2-KO mice were characterized by the predominance of the simplified type of synapses with the emergence of negative curvature of the synaptic zone in Clstn2-KO mice. Notably, presynaptic zones of cortical neurons of Clstn2-KO mice were characterized by the increased number of synaptic vesicles in opposite to the decreased number of synaptic vesicles in the presynaptic zones of hippocampal neurons. Overall, we found that lack of calsyntenin-2 leads to the striking architectonic alterations of synaptic complexes in the mouse brain, disrupting synaptic density, shape, and connectivity.
Mesh-Begriff(e)	Animals ; Calcium-Binding Proteins/deficiency ; Calcium-Binding Proteins/genetics ; Cerebral Cortex/metabolism ; Cerebral Cortex/ultrastructure ; Hippocampus/metabolism ; Hippocampus/ultrastructure ; Membrane Proteins/deficiency ; Membrane Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Synapses/metabolism ; Synapses/ultrastructure ; Synaptic Vesicles/metabolism ; Synaptic Vesicles/ultrastructure
Chemische Substanzen	Calcium-Binding Proteins ; Membrane Proteins ; calsyntenin-2, mouse
Sprache	Englisch
Erscheinungsdatum	2019-09-24
Erscheinungsland	United States
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639061-4
ISSN	1098-2396 ; 0885-8276 ; 0887-4476
ISSN (online)	1098-2396
ISSN	0885-8276 ; 0887-4476
DOI	10.1002/syn.22132
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Volltext online

Zugriff für angemeldete ZB MED Nutzerinnen und Nutzer

Zusatzmaterialien

Verfügbar in ZB MED Köln/Königswinter

Zs.A 2222: Hefte anzeigen

Standort:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Über subito bestellen

Details ▾

Artikel: Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants.

Wang, Xunan / Marmouzi, Ilias / Finnie, Peter Sb / Støve, Svein Isungset / Bucher, Meghan L / Lipina, Tatiana V / Ramsey, Amy J / Miller, Gary W / Salahpour, Ali

bioRxiv : the preprint server for biology

2023

Abstract: Vesicular monoamine transporter 2 (VMAT2) is an essential transporter that regulates brain monoamine transmission and is important for mood, cognition, motor activity, and stress regulation. However, VMAT2 remains underexplored as a pharmacological ... ...

Abstract	Vesicular monoamine transporter 2 (VMAT2) is an essential transporter that regulates brain monoamine transmission and is important for mood, cognition, motor activity, and stress regulation. However, VMAT2 remains underexplored as a pharmacological target. In this study, we report that tricyclic and tetracyclic antidepressants acutely inhibit, but persistently upregulate VMAT2 activity by promoting VMAT2 protein maturation. Importantly, the VMAT2 upregulation effect was greater in BE(2)-M17 cells that endogenously express VMAT2 as compared to a heterologous expression system (HEK293). The net sustained effect of tricyclics and tetracyclics is an upregulation of VMAT2 activity, despite their acute inhibitory effect. Furthermore, imipramine and mianserin, two representative compounds, also demonstrated rescue of nine VMAT2 variants that cause Brain Vesicular Monoamine Transport Disease (BVMTD). VMAT2 upregulation could be beneficial for disorders associated with reduced monoamine transmission, including mood disorders and BVMTD, a rare but often fatal condition caused by a lack of functional VMAT2. Our findings provide the first evidence that small molecules can upregulate VMAT2 and have potential therapeutic benefit for various neuropsychiatric conditions.
Sprache	Englisch
Erscheinungsdatum	2023-10-19
Erscheinungsland	United States
Dokumenttyp	Preprint
DOI	10.1101/2023.10.09.561601
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Fernleihe an ZB MED

Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Details ▾

Artikel ; Online: Disrupted-In-Schizophrenia-1 (DISC1) interactome and mental disorders: impact of mouse models.

Lipina, Tatiana V / Roder, John C

Neuroscience and biobehavioral reviews

2014 Band 45, Seite(n) 271–294

Abstract: Disrupted-In-Schizophrenia-1 (DISC1) has captured much attention because it predisposes individuals to a wide range of mental illnesses. Notably, a number of genes encoding proteins interacting with DISC1 are also considered to be relevant risk factors ... ...

Abstract	Disrupted-In-Schizophrenia-1 (DISC1) has captured much attention because it predisposes individuals to a wide range of mental illnesses. Notably, a number of genes encoding proteins interacting with DISC1 are also considered to be relevant risk factors of mental disorders. We reasoned that the understanding of DISC1-associated mental disorders in the context of network principles will help to address fundamental properties of DISC1 as a disease gene. Systematic integration of behavioural phenotypes of genetic mouse lines carrying perturbation in DISC1 interacting proteins would contribute to a better resolution of neurobiological mechanisms of mental disorders associated with the impaired DISC1 interactome and lead to a development of network medicine. This review also makes specific recommendations of how to assess DISC1 associated mental disorders in mouse models and discuss future directions.
Mesh-Begriff(e)	Animals ; Disease Models, Animal ; Humans ; Mental Disorders/genetics ; Mental Disorders/physiopathology ; Mice ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism
Chemische Substanzen	DISC1 protein, human ; Disc1 protein, mouse ; Nerve Tissue Proteins
Sprache	Englisch
Erscheinungsdatum	2014-09
Erscheinungsland	United States
Dokumenttyp	Journal Article ; Review
ZDB-ID	282464-4
ISSN	1873-7528 ; 0149-7634
ISSN (online)	1873-7528
ISSN	0149-7634
DOI	10.1016/j.neubiorev.2014.07.001
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Volltext online

Zugriff für angemeldete ZB MED Nutzerinnen und Nutzer

Zusatzmaterialien

Verfügbar in ZB MED Köln/Königswinter

Zs.A 1371: Hefte anzeigen

Standort:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Über subito bestellen

Details ▾

Artikel ; Online: Co-learning facilitates memory in mice: a new avenue in social neuroscience.

Lipina, Tatiana V / Roder, John C

Neuropharmacology

2013 Band 64, Seite(n) 283–293

Abstract: Social context affects brain function but our understanding of its neurobiology is at an early stage. The mere presence of one individual can alter the cognitive capacities of another and social learning has been demonstrated in many species, including ... ...

Abstract	Social context affects brain function but our understanding of its neurobiology is at an early stage. The mere presence of one individual can alter the cognitive capacities of another and social learning has been demonstrated in many species, including the mouse. We asked several questions: 1. How can active engagement of two familiar mice in the same learning activity (co-learning) alter their memory? 2. Under which environmental conditions (aversive vs non-aversive) can we expect the memory to be enhanced, impaired, or not affected? 3. Can a genetic factor modify the co-learning effect on memory? More specifically, can co-learning correct memory deficits in autistic-like BTBR inbred mice with deficient sociability? We demonstrated that pairs of familiar inbred mice of the same or different genotypes (C57BL/6J and BTBR) that were habituated to new objects and their spatial location, had enhanced episodic memory in the spatial object recognition test, whereas individually-trained animals failed to solve this task. Notably, the co-learning effect was genotype-dependent. BTBR mice paired with BTBR cage-mates in the habituation session modestly ameliorated their performance in the object recognition test but co-learning with a familiar C57BL/6J mouse completely normalized episodic memory deficit. Next, we explored the co-learning effect on fear memory in these inbred strains. Interestingly, mice of both genotypes displayed significantly enhanced contextual fear memory once they had been conditioned together with BTBR animals. The same influence of BTBR presence was observed on cued fear memory in C57BL/6J mice, whereas a modest co-learning effect was found on cued fear conditioning in the BTBR strain. Taken together, we demonstrated for the first time the co-learning effect on cognitive capacities in mice, which can be modified by genetic background and environmental conditions. The possible implications of this methodological approach in social neuroscience are discussed. This article is part of a Special Issue entitled 'Cognitive Enhancers'.
Mesh-Begriff(e)	Animals ; Autistic Disorder/physiopathology ; Autistic Disorder/therapy ; Behavior, Animal ; Cognition ; Cognition Disorders/etiology ; Cognition Disorders/prevention & control ; Conditioning (Psychology) ; Disease Models, Animal ; Exploratory Behavior ; Habituation, Psychophysiologic ; Learning ; Male ; Memory ; Memory Disorders/etiology ; Memory Disorders/prevention & control ; Mice ; Mice, Inbred C57BL ; Mice, Inbred Strains ; Recognition (Psychology) ; Social Behavior ; Social Behavior Disorders/etiology ; Social Behavior Disorders/prevention & control ; Vocalization, Animal
Sprache	Englisch
Erscheinungsdatum	2013-01
Erscheinungsland	England
Dokumenttyp	Comparative Study ; Journal Article
ZDB-ID	218272-5
ISSN	1873-7064 ; 0028-3908
ISSN (online)	1873-7064
ISSN	0028-3908
DOI	10.1016/j.neuropharm.2012.06.054
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Volltext online

Zugriff für angemeldete ZB MED Nutzerinnen und Nutzer

Zusatzmaterialien

Verfügbar in ZB MED Köln/Königswinter

Ui I Zs.242: Hefte anzeigen

Standort:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Über subito bestellen

Details ▾

Artikel ; Online: Vocal and physical phenotypes of calsyntenin2 knockout mouse pups model early-life symptoms of the autism spectrum disorder.

Klenova, Anna V / Volodin, Ilya A / Volodina, Elena V / Ranneva, Svetlana V / Amstislavskaya, Tamara G / Lipina, Tatiana V

Behavioural brain research

2021 Band 412, Seite(n) 113430

Abstract: This study discovered a novel acoustic phenotype in Calsyntenin2 deficient knockout (Clstn2-KO) pups in the neurodevelopment period of 5-9 postnatal days (PND 5-9). The narrowband ultrasonic calls (nUSVs) were less complex (mostly one-note, shorter in ... ...

Abstract	This study discovered a novel acoustic phenotype in Calsyntenin2 deficient knockout (Clstn2-KO) pups in the neurodevelopment period of 5-9 postnatal days (PND 5-9). The narrowband ultrasonic calls (nUSVs) were less complex (mostly one-note, shorter in duration and higher in peak frequency) in Clsnt2-KO than in wild-type (WT) C57BL/6 J pups. The wideband ultrasonic calls (wUSVs) were produced substantially more often by Clstn2-KO than WT pups. The clicks were longer in duration and higher in peak frequency and power quartiles in Clstn2-KO pups. The elevated discomfort due to additional two-minute maternal separation coupled with experimenter's touch, resulted in significantly higher call rates of both nUSVs and clicks in pups of both genotypes and sexes compared to the previous two-minute maternal separation, whereas the call rate of wUSVs was not affected. In Clstn2-KO pups, the prevalence of emission of wUSVs retained at both sex and both degrees of discomfort, thus providing a reliable quantitative acoustic indicator for this genetic line. Besides the acoustic differences, we also detected the increased head-to-body ratio in Clstn2-KO pups. Altogether, this study demonstrated that lack of such synaptic adhesion protein as calsyntenin2 affects neurodevelopment of vocalization in a mouse as a model organism.
Mesh-Begriff(e)	Acoustics ; Animals ; Autism Spectrum Disorder/genetics ; Autism Spectrum Disorder/metabolism ; Calcium-Binding Proteins/genetics ; Calcium-Binding Proteins/metabolism ; Disease Models, Animal ; Female ; Male ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Phenotype ; Ultrasonics ; Vocalization, Animal/physiology
Chemische Substanzen	Calcium-Binding Proteins ; Membrane Proteins ; calsyntenin-2, mouse
Sprache	Englisch
Erscheinungsdatum	2021-06-25
Erscheinungsland	Netherlands
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	449927-x
ISSN	1872-7549 ; 0166-4328
ISSN (online)	1872-7549
ISSN	0166-4328
DOI	10.1016/j.bbr.2021.113430
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Volltext online

Zugriff für angemeldete ZB MED Nutzerinnen und Nutzer

Zusatzmaterialien

Verfügbar in ZB MED Köln/Königswinter

Zs.A 1599: Hefte anzeigen

Standort:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Über subito bestellen

Details ▾

Artikel ; Online: Conditioned stimulus presentations alter anxiety level in fear-conditioned mice.

Zhang, Yujie / Ouyang, Kunfu / Lipina, Tatiana V / Wang, Hong / Zhou, Qiang

Molecular brain

2019 Band 12, Heft 1, Seite(n) 28

Abstract: It is generally believed that fear is rapidly triggered by a distinct cue while anxiety onset is less precise and not associated with a distinct cue. Although it has been claimed that both processes can be measured with certain independence of each other, ...

Abstract	It is generally believed that fear is rapidly triggered by a distinct cue while anxiety onset is less precise and not associated with a distinct cue. Although it has been claimed that both processes can be measured with certain independence of each other, it is unclear how exactly they differ. In this study, we measured anxiety in mice that received discriminative fear conditioning using behavioral, heart rate and calcium (Ca
Mesh-Begriff(e)	Animals ; Anxiety/drug therapy ; Anxiety/pathology ; Anxiety/physiopathology ; Calcium/metabolism ; Conditioning, Classical/drug effects ; Conditioning, Classical/physiology ; Diazepam/pharmacology ; Diazepam/therapeutic use ; Discrimination, Psychological ; Fear/drug effects ; Fear/physiology ; Freezing Reaction, Cataleptic/physiology ; Heart Rate/drug effects ; Hypothalamus/drug effects ; Hypothalamus/pathology ; Hypothalamus/physiopathology ; Lipopeptides/pharmacology ; Male ; Mice, Inbred C57BL ; Neurons/drug effects ; Neurons/metabolism ; Protein Kinase C/antagonists & inhibitors ; Protein Kinase C/metabolism
Chemische Substanzen	Lipopeptides ; zeta-inhibitory peptide ; protein kinase C zeta (EC 2.7.11.1) ; Protein Kinase C (EC 2.7.11.13) ; Diazepam (Q3JTX2Q7TU) ; Calcium (SY7Q814VUP)
Sprache	Englisch
Erscheinungsdatum	2019-03-29
Erscheinungsland	England
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2436057-0
ISSN	1756-6606 ; 1756-6606
ISSN (online)	1756-6606
ISSN	1756-6606
DOI	10.1186/s13041-019-0445-4
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Über subito bestellen

Details ▾
- Kostenpflichtig bestellen

Artikel: Lung inflammation is associated with lipid deposition.

Potashnikova, Daria M / Tvorogova, Anna V / Saidova, Aleena A / Sotnikova, Tatiana N / Arifulin, Eugene A / Lipina, Tatiana V / Shirokova, Olesya M / Melnikov, Eugene S / Rodina, Tatiana A / Valyaeva, Anna A / Zharikova, Anastasia A / Zayratyants, George O / Zayratyants, Oleg V / Sheval, Eugene V / Vasilieva, Elena J

bioRxiv : the preprint server for biology

2023

Abstract: Lung inflammation, pneumonia, is an acute respiratory disease of varying etiology that has recently drawn much attention during the COVID-19 pandemic as lungs are among the main targets for SARS-CoV-2. Multiple other etiological agents are associated ... ...

Abstract	Lung inflammation, pneumonia, is an acute respiratory disease of varying etiology that has recently drawn much attention during the COVID-19 pandemic as lungs are among the main targets for SARS-CoV-2. Multiple other etiological agents are associated with pneumonias. Here, we describe a newly-recognized pathology, namely abnormal lipid depositions in the lungs of patients who died from COVID-19 as well as from non-COVID-19 pneumonias. Our analysis of both semi-thin and Sudan III-stained lung specimens revealed extracellular and intracellular lipid depositions irrespective of the pneumonia etiology. Most notably, lipid depositions were located within vessels adjacent to inflamed regions, where they apparently interfere with the blood flow. Structurally, the lipid droplets in the inflamed lung tissue were homogeneous and lacked outer membranes as assessed by electron microscopy. Morphometric analysis of lipid droplet deposition area allowed us to distinguish the non-pneumonia control lung specimens from the macroscopically intact area of the pneumonia lung and from the inflamed area of the pneumonia lung. Our measurements revealed a gradient of lipid deposition towards the inflamed region. The pattern of lipid distribution proved universal for all pneumonias. Finally, lipid metabolism in the lung tissue was assessed by the fatty acid analysis and by expression of genes involved in lipid turnover. Chromato-mass spectrometry revealed that unsaturated fatty acid content was elevated at inflammation sites compared to that in control non-inflamed lung tissue from the same individual. The expression of genes involved in lipid metabolism was altered in pneumonia, as shown by qPCR and in silico RNA-seq analysis. Thus, pneumonias of various etiologies are associated with specific lipid abnormalities; therefore, lipid metabolism can be considered to be a target for new therapeutic strategies.
Sprache	Englisch
Erscheinungsdatum	2023-11-20
Erscheinungsland	United States
Dokumenttyp	Preprint
DOI	10.1101/2022.12.30.522299
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Fernleihe an ZB MED

Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Details ▾

Artikel: Ultrasonic Vocalizations in Mice During Exploratory Behavior are Context-Dependent.

Mun, Ho-Suk / Lipina, Tatiana V / Roder, John C

Frontiers in behavioral neuroscience

2015 Band 9, Seite(n) 316

Abstract: While rat ultrasonic vocalizations (USVs) are known to vary with anticipation of an aversive vs. positive stimulus, little is known about USVs in adult mice in relation to behaviors. We recorded the calls of adult C57BL/6J male mice under different ... ...

Abstract	While rat ultrasonic vocalizations (USVs) are known to vary with anticipation of an aversive vs. positive stimulus, little is known about USVs in adult mice in relation to behaviors. We recorded the calls of adult C57BL/6J male mice under different environmental conditions by exposing mice to both novel and familiar environments that varied in stress intensity through the addition of bright light or shallow water. In general, mouse USVs were significantly more frequent and of longer duration in novel environments. Particularly, mice in dimly-lit novel environments performed more USVs while exhibiting unsupported rearing and walking behavior, and these calls were mostly at high frequency. In contrast, mice exhibited more low frequency USVs when engaging in supported rearing behavior in novel environments. These findings are consistent with data from rats suggesting that low-frequency calls are made under aversive conditions and high-frequency calls occur in non-stressful conditions. Our findings increase understanding of acoustic signals associated with exploratory behaviors relevant to cognitive and motivational aspects of behavior.
Sprache	Englisch
Erscheinungsdatum	2015-12-10
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	2452960-6
ISSN	1662-5153
ISSN	1662-5153
DOI	10.3389/fnbeh.2015.00316
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Über subito bestellen

Details ▾
- Kostenpflichtig bestellen

Zum Seitenanfang

Ihre letzten Suchen

Zusatzmaterialien

Kategorien

Über subito bestellen

Zusatzmaterialien

Kategorien

Über subito bestellen

Fernleihe an ZB MED

Volltext online

Zusatzmaterialien

Kategorien

Verfügbar in ZB MED Köln/Königswinter

Über subito bestellen

Zusatzmaterialien

Kategorien

Fernleihe an ZB MED

Volltext online

Zusatzmaterialien

Kategorien

Verfügbar in ZB MED Köln/Königswinter

Über subito bestellen

Volltext online

Zusatzmaterialien

Kategorien

Verfügbar in ZB MED Köln/Königswinter

Über subito bestellen

Volltext online

Zusatzmaterialien

Kategorien

Verfügbar in ZB MED Köln/Königswinter

Über subito bestellen

Zusatzmaterialien

Kategorien

Über subito bestellen

Zusatzmaterialien

Kategorien

Fernleihe an ZB MED

Zusatzmaterialien

Kategorien

Über subito bestellen