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Book: Grow in concert with nature

Xiaokai Li / Turner, Graeme / Liping Jiang

sustaining East Asia's water resources through green water defense

(A World Bank study)

2012

Author's details	Xiaokai Li, Graeme Turner, and Liping Jiang
Series title	A World Bank study
Language	English
Size	XVII, 86 S. : Ill., graph. Darst., Kt.
Publisher	World Bank
Publishing place	Washington DC
Publishing country	United States
Document type	Book
Note	Includes bibliographical references
HBZ-ID	HT017325136
ISBN	978-0-8213-9588-2 ; 9780821395974 ; 0-8213-9588-2 ; 0821395971
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

In stock of ZB MED Bonn / Germany

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124/399	available for loan (reading room)	Freihandmagazin (U1)

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Article ; Online: Stiffening of the gluteal muscle increased the intramuscular stress

Jingyi Jia / Shengbo Gong / Aili Zhang / Liping Jiang / Yifei Yao

Heliyon, Vol 9, Iss 2, Pp e13459- (2023)

An in-silico implication of deep tissue injury

2023

Abstract: Objectives: Deep tissue injury is a common form of pressure ulcers in muscle tissues under bony prominences caused by sustained pressure or shear, which has a great impact on patients with restricted mobility such as spinal cord injury. Frequent spasms ... ...

Abstract	Objectives: Deep tissue injury is a common form of pressure ulcers in muscle tissues under bony prominences caused by sustained pressure or shear, which has a great impact on patients with restricted mobility such as spinal cord injury. Frequent spasms in spinal cord injury patients featured by muscle stiffening may be one of the factors leading to deep tissue injury. The purpose of this study was to investigate the relationship between the gluteal muscle shear modulus and intramuscular compressive/shear stress/strain. Methods: A semi-3D finite element model of the human buttock was established using COMSOL software and the acquired biomechanical data were analyzed through Pearson correlation and Spearman correlation. Results: Results showed that the compressive stress, strain energy density, and average von Mises stress increased with the increase of the gluteal muscle shear modulus. Conclusion: These results may indicate muscle stiffening caused by muscle spasms could lead to higher deep tissue injury development risk as well as shed light on effective treatments for relieving muscular sclerosis mechanically.
Keywords	Deep tissue injury ; Muscle spasm ; Muscle shear modulus ; Finite element analysis ; Intramuscular stress ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	610
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Evolving Insights Into the Biological Function and Clinical Significance of Long Noncoding RNA in Glioblastoma

Kun Liu / Hong Chen / Yuanyuan Wang / Liping Jiang / Yi Li

Frontiers in Cell and Developmental Biology, Vol

2022 Volume 10

Abstract: Glioblastoma (GBM) is one of the most prevalent and aggressive cancers worldwide. The overall survival period of GBM patients is only 15 months even with standard combination therapy. The absence of validated biomarkers for early diagnosis mainly ... ...

Abstract	Glioblastoma (GBM) is one of the most prevalent and aggressive cancers worldwide. The overall survival period of GBM patients is only 15 months even with standard combination therapy. The absence of validated biomarkers for early diagnosis mainly accounts for worse clinical outcomes of GBM patients. Thus, there is an urgent requirement to characterize more biomarkers for the early diagnosis of GBM patients. In addition, the detailed molecular basis during GBM pathogenesis and oncogenesis is not fully understood, highlighting that it is of great significance to elucidate the molecular mechanisms of GBM initiation and development. Recently, accumulated pieces of evidence have revealed the central roles of long noncoding RNAs (lncRNAs) in the tumorigenesis and progression of GBM by binding with DNA, RNA, or protein. Targeting those oncogenic lncRNAs in GBM may be promising to develop more effective therapeutics. Furthermore, a better understanding of the biological function and underlying molecular basis of dysregulated lncRNAs in GBM initiation and development will offer new insights into GBM early diagnosis and develop novel treatments for GBM patients. Herein, this review builds on previous studies to summarize the dysregulated lncRNAs in GBM and their unique biological functions during GBM tumorigenesis and progression. In addition, new insights and challenges of lncRNA-based diagnostic and therapeutic potentials for GBM patients were also introduced.
Keywords	lncRNA ; glioblastoma ; diagnostic biomarker ; prognostic biomarker ; targeted therapy ; Biology (General) ; QH301-705.5
Subject code	610
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Theoretical Calculations and Experiments on the Thermal Properties of Fluorinated Graphene and Its Effects on the Thermal Decomposition of Nitrate Esters

Saiqin Meng / Xiaolong Fu / Liping Jiang / La Shi / Xu Wang / Xiangyang Liu / Jiangning Wang

Nanomaterials, Vol 12, Iss 621, p

2022 Volume 621

Abstract: Fluorinated graphene contains F atoms with high levels of chemical activity, and the application of fluorinated graphene in energetic materials may greatly contribute to the progress of combustion reactions. However, there is a lack of research on the ... ...

Abstract	Fluorinated graphene contains F atoms with high levels of chemical activity, and the application of fluorinated graphene in energetic materials may greatly contribute to the progress of combustion reactions. However, there is a lack of research on the thermal properties of fluorinated graphene and its application on nitrate esters. In this paper, theoretical calculations and experiments were used to study the thermal properties of fluorinated graphene and its application on nitrate esters. The anaerobicity and poor thermal stability of fluorinated graphene were proved by ab initio molecular dynamics (AIMD) calculations and TG-DSC experiments. The ester weakening effect of fluorinated graphene on nitroglycerin was determined via wavefunction analysis, with the greater the fluorination degree, the stronger the ester weakening effect. The existence of fluorinated graphene can significantly increase the heat dissipation of the composites, which was concluded by TG-DSC experiments and TG-DSC-MS-FTIR. The research in this article provides an important reference for the application of fluorinated graphene in energetic materials.
Keywords	two dimensional materials ; energetic materials ; fluorinated graphene ; nitrate esters ; thermal decomposition ; Chemistry ; QD1-999
Subject code	540
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Epstein-Barr Virus and Neurological Diseases

Nan Zhang / Yuxin Zuo / Liping Jiang / Yu Peng / Xu Huang / Lielian Zuo

Frontiers in Molecular Biosciences, Vol

2022 Volume 8

Abstract: Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a double-stranded DNA virus that is ubiquitous in 90–95% of the population as a gamma herpesvirus. It exists in two main states, latent infection and lytic replication, each encoding viral ... ...

Abstract	Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a double-stranded DNA virus that is ubiquitous in 90–95% of the population as a gamma herpesvirus. It exists in two main states, latent infection and lytic replication, each encoding viral proteins with different functions. Human B-lymphocytes and epithelial cells are EBV-susceptible host cells. EBV latently infects B cells and nasopharyngeal epithelial cells throughout life in most immunologically active individuals. EBV-infected cells, free viruses, their gene products, and abnormally elevated EBV titers are observed in the cerebrospinal fluid. Studies have shown that EBV can infect neurons directly or indirectly via infected B-lymphocytes, induce neuroinflammation and demyelination, promote the proliferation, degeneration, and necrosis of glial cells, promote proliferative disorders of B- and T-lymphocytes, and contribute to the occurrence and development of nervous system diseases, such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, acute cerebellar ataxia, meningitis, acute disseminated encephalomyelitis, and brain tumors. However, the specific underlying molecular mechanisms are unclear. In this paper, we review the mechanisms underlying the role of EBV in the development of central nervous system diseases, which could bebeneficial in providing new research ideas and potential clinical therapeutic targets for neurological diseases.
Keywords	epstein-barr virus ; neuroinflammation ; multiple sclerosis ; alzheimer’s disease ; immunoreaction ; EBNA1 ; Biology (General) ; QH301-705.5
Subject code	610
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Mitochondrial iron overload mediated by cooperative transfer of plasma membrane ATP5B and TFR2 to mitochondria triggers hepatic insulin resistance under PFOS exposure

Jianyu Wang / Jinling Wang / Tianming Qiu / Jialu Wu / Xiance Sun / Liping Jiang / Xiaofang Liu / Guang Yang / Jun Cao / Xiaofeng Yao

Ecotoxicology and Environmental Safety, Vol 253, Iss , Pp 114662- (2023)

2023

Abstract: In general populations, insulin resistance (IR) is related to perfluorooctane sulfonate (PFOS), a persistent organic pollutant. However, the underlying mechanism remains unclear. In this study, PFOS induced mitochondrial iron accumulation in the liver of ...

Abstract	In general populations, insulin resistance (IR) is related to perfluorooctane sulfonate (PFOS), a persistent organic pollutant. However, the underlying mechanism remains unclear. In this study, PFOS induced mitochondrial iron accumulation in the liver of mice and human hepatocytes L-O2. In the PFOS-treated L-O2 cells, mitochondrial iron overload preceded the occurrence of IR, and pharmacological inhibition of mitochondrial iron relieved PFOS-caused IR. Both transferrin receptor 2 (TFR2) and ATP synthase β subunit (ATP5B) were redistributed from the plasma membrane to mitochondria with PFOS treatment. Inhibiting the translocation of TFR2 to mitochondria reversed PFOS-induced mitochondrial iron overload and IR. In the PFOS-treated cells, ATP5B interacted with TFR2. Stabilizing ATP5B on the plasma membrane or knockdown of ATP5B disturbed the translocation of TFR2. PFOS inhibited the activity of plasma-membrane ATP synthase (ectopic ATP synthase, e-ATPS), and activating e-ATPS prevented the translocation of ATP5B and TFR2. Consistently, PFOS induced ATP5B/TFR2 interaction and redistribution of ATP5B and TFR2 to mitochondria in the liver of mice. Thus, our results indicated that mitochondrial iron overload induced by collaborative translocation of ATP5B and TFR2 was an up-stream and initiating event for PFOS-related hepatic IR, providing novel understandings of the biological function of e-ATPS, the regulatory mechanism for mitochondrial iron and the mechanism underlying PFOS toxicity.
Keywords	Perfluorooctane sulphonate ; Mitochondrial iron ; Ectopic ATP synthase ; Transferrin receptor 2 ; Insulin resistance ; Environmental pollution ; TD172-193.5 ; Environmental sciences ; GE1-350
Subject code	570
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Association between toileting and falls in older adults admitted to the emergency department and hospitalised

Ping Liu / Liping Jiang / Xiaoling Wang / Rong Lu / Min Zou / Yijun Jiang / Bingjie Tian / Yuqi Liang

BMJ Open, Vol 13, Iss

a cross-sectional study

2023 Volume 6

Abstract: Objectives This study aimed to explore the potential risk factors associated with toileting-related falls in community-dwelling older adults who presented to the emergency department and were subsequently hospitalised.Design This was a cross-sectional ... ...

Abstract	Objectives This study aimed to explore the potential risk factors associated with toileting-related falls in community-dwelling older adults who presented to the emergency department and were subsequently hospitalised.Design This was a cross-sectional study.Setting and participants This study was conducted in two teaching hospitals in Shanghai, China between October 2019 and December 2021 among community-dwelling adults aged ≥60 years.Methods In-person interviews, physical assessment and medical record review were performed to collect data on the characteristics and risk factors of falls. Associations of toileting-related falls with demographic characteristics and geriatric syndromes were examined using logistic regression models.Main outcome measures Potential risk factors for toileting-related falls.Results This study included 419 older patients with a mean age of 73.8±9.7 years. Among 60 (14.3%) patients with toileting-related falls (mean age: 78.8±9.2 years), 63.3% of toileting-related falls, mainly occurred between 00:00 and 05:59 hours, compared with 17.3% of non-toileting-related falls, which primarily occurred during the daytime. The rate of recurrent falls (35%) was significantly higher in the toileting-related falls group than in the non-toileting-related falls group (21.2%) (p=0.02). Logistic regression showed that visual impairment (OR 2.7, 95% CI 1.1 to 7.1), cognitive impairment (OR 3.3, 95% CI 1.3 to 8.4), gait instability (OR 3.1, 95% CI 1.1 to 8.8) and urinary incontinence (OR 3.4, 95% CI 1.2 to 9.9) were strongly associated with toileting-related falls. Twenty-three (38.3%) patients in the toileting-related falls group had moderate and severe injuries, compared with 71.7% in the non-toileting-related falls group (p<0.05).Conclusions This study revealed that patients who reported toileting-related falls were more likely to have cognitive impairment, urinary incontinence, gait instability, visual impairment than patients who fell during other activities. Social and healthcare professionals ...
Keywords	Medicine ; R
Subject code	150
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	BMJ Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Time Reliability of the Maritime Transportation Network for China’s Crude Oil Imports

Shuang Wang / Jing Lu / Liping Jiang

Sustainability, Vol 12, Iss 1, p

2019 Volume 198

Abstract: To evaluate the transportation time reliability of the maritime transportation network for China’s crude oil imports under node capacity variations resulting from extreme events, a framework incorporating bi-level programming and a Monte Carlo simulation ...

Abstract	To evaluate the transportation time reliability of the maritime transportation network for China’s crude oil imports under node capacity variations resulting from extreme events, a framework incorporating bi-level programming and a Monte Carlo simulation is proposed in this paper. Under this framework, the imported crude oil volume from each source country is considered to be a decision variable, and may change in correspondence to node capacity variations. The evaluation results illustrate that when strait or canal nodes were subject to capacity variations, the network transportation time reliability was relatively low. Conversely, the transportation time reliability was relatively high when port nodes were under capacity variations. In addition, the Taiwan Strait, the Strait of Hormuz, and the Strait of Malacca were identified as vulnerable nodes according to the transportation time reliability results. These results can assist government decision-makers and tanker company strategic planners to better plan crude oil import and transportation strategies.
Keywords	transportation time reliability ; china’s crude oil imports ; maritime transportation network ; capacity variations ; bi-level programming ; monte carlo simulation ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	380
Language	English
Publishing date	2019-12-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Preparation, Characterization and Application of Nano-Graphene-Based Energetic Materials

Xiaolong Fu / Yonghu Zhu / Jizhen Li / Liping Jiang / Xitong Zhao / Xuezhong Fan

Nanomaterials, Vol 11, Iss 2374, p

2021 Volume 2374

Abstract: Nano-graphene-based energetic materials, as a new type of composite energetic materials such as desensitizer and combustion catalyst, have attracted extensive attention from energetic researchers. In this paper, the preparation of nano-graphene-based ... ...

Abstract	Nano-graphene-based energetic materials, as a new type of composite energetic materials such as desensitizer and combustion catalyst, have attracted extensive attention from energetic researchers. In this paper, the preparation of nano-graphene-based energetic materials, the desensitization effect of nano-graphene-based on energetic compounds, the thermal decomposition and combustion behavior of the materials are reviewed. Meanwhile, the existing problems and future development of nano-graphene-based energetic compounds are discussed.
Keywords	applied chemistry ; energetic materials ; nano-graphene ; preparation ; desensitization ; combustion ; Chemistry ; QD1-999
Language	English
Publishing date	2021-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Correction

Yuan Liu / Yaqin Tang / Xing Tang / Mengqi Wu / Shengjie Hou / Xiaohua Liu / Jing Li / Meichun Deng / Shuaiqin Huang / Liping Jiang

Biomedicines, Vol 10, Iss 1176, p

Liu et al. Anti- Toxoplasma gondii Effects of a Novel Spider Peptide XYP1 In Vitro and In Vivo. Biomedicines 2021, 9 , 934

2022 Volume 1176

Abstract: In the original publication, there were mistakes in Figure 3C, Figure 6B and Figure S2A,B as published [.] ...

Abstract	In the original publication, there were mistakes in Figure 3C, Figure 6B and Figure S2A,B as published [.]
Keywords	n/a ; Biology (General) ; QH301-705.5
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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