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Article ; Online: Isospin transfer modes in exotic nuclei

Litvinova Elena

EPJ Web of Conferences, Vol 93, p

2015 Volume 01019

Abstract: This work presents an approach to nuclear spin-isospin response, which is capable of describing the overall strength distribution up to high excitation energies, including the fine structure of the low-lying strength, and resolving the long-standing ... ...

Abstract	This work presents an approach to nuclear spin-isospin response, which is capable of describing the overall strength distribution up to high excitation energies, including the fine structure of the low-lying strength, and resolving the long-standing quenching problem. The model is a covariant realization of the nuclear field theory and based on the self-consistent extensions of the covariant energy density functional (CEDF) theory. Results of the recent calculations for spin-isospin response of ordinary and exotic medium-mass nuclei are presented and discussed.
Keywords	Science ; Q ; Physics ; QC1-999
Language	English
Publishing date	2015-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Time-Reversed Particle-Vibration Loops and Nuclear Gamow-Teller Response.

Robin, Caroline / Litvinova, Elena

Physical review letters

2019 Volume 123, Issue 20, Page(s) 202501

Abstract: The nuclear response theory for charge-exchange modes in the relativistic particle-vibration coupling approach is extended to include for the first time particle-vibration coupling effects in the ground state of the parent nucleus. In a framework based ... ...

Abstract	The nuclear response theory for charge-exchange modes in the relativistic particle-vibration coupling approach is extended to include for the first time particle-vibration coupling effects in the ground state of the parent nucleus. In a framework based on the effective meson-nucleon Lagrangian, we investigate the role of such complex ground-state correlations in the description of Gamow-Teller transitions in ^{90}Zr in both (p, n) and (n, p) channels. The particle-vibration coupling effects are calculated without introducing new parameters. We find that this new correlation mechanism is fully responsible for the appearance of the strength in the (n, p) branch. Comparison of our results to the available experimental data shows a very good agreement up to excitation energies beyond the giant resonance region when taking into account a phenomenological admixture of the isovector spin monopole transitions. The parent-daughter binding-energy differences are also greatly improved by the inclusion of the new correlations.
Language	English
Publishing date	2019-12-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.123.202501
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Article ; Online: Implementation of the agricultural university educational programs during a pandemic

Filimonyuk Ludmila / Ivashova Valentine / Burlyaeva Victoria / Sorokina Elena / Litvinova Elena

E3S Web of Conferences, Vol 258, p

participants’ opinions

2021 Volume 10017

Abstract: The article presents the results of a study of the opinions of students and teachers of the southern region of Russia about the learning process in higher education programs during the COVID-19 pandemic. We carried out a comparative analysis of the ... ...

Abstract	The article presents the results of a study of the opinions of students and teachers of the southern region of Russia about the learning process in higher education programs during the COVID-19 pandemic. We carried out a comparative analysis of the quality of the implementation of educational programs in the assessments of participants in the process during the onset of the COVID-19 pandemic (April-May 2020) and its peak values (November-December 2020). The positive and negative consequences of transferring training to a distance learning format are formulated. Among the positive consequences are: the availability of training from anywhere; more flexible training, focused on the educational needs of students; new formats of social student life; more accessible communication with teachers. We analyzed the experience of the educational community presented in publications during the COVID-19 pandemic. The data obtained provide an understanding of the importance of the development and implementation of new organizational and methodological approaches for the effective response of higher education to external global challenges of our time.
Keywords	Environmental sciences ; GE1-350
Subject code	028
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Finite-Temperature Relativistic Nuclear Field Theory: An Application to the Dipole Response.

Litvinova, Elena / Wibowo, Herlik

Physical review letters

2018 Volume 121, Issue 8, Page(s) 82501

Abstract: Nuclear response theory beyond the one-loop approximation is formulated for the case of finite temperature. For this purpose, the time blocking approximation to the time-dependent part of the in-medium nucleon-nucleon interaction amplitude is adopted for ...

Abstract	Nuclear response theory beyond the one-loop approximation is formulated for the case of finite temperature. For this purpose, the time blocking approximation to the time-dependent part of the in-medium nucleon-nucleon interaction amplitude is adopted for the thermal (imaginary-time) Green's function formalism. We found that introducing a soft blocking, instead of a sharp blocking at zero temperature, brings the Bethe-Salpeter equation to a single-frequency variable equation also at finite temperatures. The method is implemented self-consistently in the framework of quantum hadrodynamics and designed to connect the high-energy scale of heavy mesons and the low-energy domain of nuclear medium polarization effects in a parameter-free way. In this framework, we investigate the temperature dependence of dipole spectra in the even-even nuclei ^{48}Ca and ^{100,120,132}Sn with a special focus on the giant dipole resonance's width problem and on the low-energy dipole strength distribution.
Language	English
Publishing date	2018-09-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.121.082501
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Article ; Online: Cell-Mediated Immune Responses to COVID-19 Infection.

Guihot, Amélie / Litvinova, Elena / Autran, Brigitte / Debré, Patrice / Vieillard, Vincent

Frontiers in immunology

2020 Volume 11, Page(s) 1662

Abstract: An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV), subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan City (China) in December 2019. Despite rigorous containment and quarantine efforts, the incidence ... ...

Abstract	An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV), subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan City (China) in December 2019. Despite rigorous containment and quarantine efforts, the incidence of COVID-19 continues to expand, causing explosive outbreaks in more than 160 countries with waves of morbidity and fatality, leading to significant public health problems. In the past 20 years, two additional epidemics caused by CoVs have occurred: severe acute respiratory syndrome-CoV, which has caused a large-scale epidemic in China and 24 other countries; and respiratory syndrome-CoV of the Middle East in Saudi Arabia, which continues to cause sporadic cases. All of these viruses affect the lower respiratory tract and manifest as pneumonia in humans, but the novel SARS-Cov-2 appears to be more contagious and has spread more rapidly worldwide. This mini-review focuses on the cellular immune response to COVID-19 in human subjects, compared to other clinically relevant coronaviruses to evaluate its role in the control of infection and pathogenesis and accelerate the development of a preventive vaccine or immune therapies.
MeSH term(s)	Betacoronavirus/immunology ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/immunology ; Coronavirus Infections/therapy ; Epidemics ; Humans ; Immunity, Cellular ; Immunotherapy ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/immunology ; Pneumonia, Viral/therapy ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-07-03
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2020.01662
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: MAIT cells altered phenotype and cytotoxicity in lupus patients are linked to renal disease severity and outcome.

Litvinova, Elena / Bounaix, Carine / Hanouna, Guillaume / Da Silva, Jennifer / Noailles, Laura / Beaudoin, Lucie / Padden, Michael / Bellamri, Nessrine / Lehuen, Agnès / Daugas, Eric / Monteiro, Renato C / Flament, Héloïse

Frontiers in immunology

2023 Volume 14, Page(s) 1205405

Abstract: Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disease in which circulating immune complexes can cause different types of glomerulonephritis, according to immune deposits and to the type of glomerular cell injury. Proliferative ... ...

Abstract	Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disease in which circulating immune complexes can cause different types of glomerulonephritis, according to immune deposits and to the type of glomerular cell injury. Proliferative lesions represent the most severe form of lupus nephritis (LN) and often lead to kidney failure and death. Mucosal-associated invariant T (MAIT) cells are a subset of innate-like T cells that recognize microbial-derived ligands from the riboflavin synthesis pathway. Although abundant in peripheral blood, MAIT cells are enriched in mucosal and inflamed tissues. While previous studies have reported concordant results concerning lower MAIT cell frequencies in the blood of SLE patients, no information is known about MAIT cell function and LN severity and outcome. Methods: In the current study, we analyzed the baseline phenotype and function of peripheral blood MAIT cells by flow cytometry in 26 patients with LN and in a control group of 16 healthy individuals. Results: We observe that MAIT cell frequencies are markedly reduced in blood of LN patients. MAIT cells from patients have an altered phenotype in terms of migration, proliferation and differentiation markers, notably in most severe forms of LN. Frequencies of PMA/ionomycin stimulated MAIT cells secreting effector molecules, such as proinflammatory IL-17 and cytotoxic protein granzyme B, are higher in LN patients. Patients undergoing a complete renal remission after immunosuppressive therapy had higher MAIT cell frequency, lower expression of proliferation marker Ki-67 and granzyme B (GzB) at inclusion. Remarkably, GzB production defines a predictive model for complete remission. Discussion: We report here that blood MAIT cells display proinflammatory and cytotoxic function in severe lupus nephritis which may play a pathogenesis role, but without association with systemic lupus activity. Finally, low cytotoxic profile of MAIT cells may represent a promising prognostic factor of lupus nephritis remission one year after induction therapy.
MeSH term(s)	Humans ; Lupus Nephritis ; Mucosal-Associated Invariant T Cells ; Granzymes ; Lupus Erythematosus, Systemic ; Phenotype ; Patient Acuity
Chemical Substances	Granzymes (EC 3.4.21.-)
Language	English
Publishing date	2023-10-10
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2023.1205405
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Cell-Mediated Immune Responses to COVID-19 Infection

Guihot, Amélie / Litvinova, Elena / Autran, Brigitte / Debré, Patrice / Vieillard, Vincent

Frontiers in Immunology

2020 Volume 11

Keywords	covid19
Publisher	Frontiers Media SA
Publishing country	ch
Document type	Article ; Online
ZDB-ID	2606827-8
ISSN	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2020.01662
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Cell-Mediated Immune Responses to COVID-19 Infection

Guihot, Amélie / Litvinova, Elena / Autran, Brigitte / Debré, Patrice / Vieillard, Vincent

Front Immunol

Abstract	An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV), subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan City (China) in December 2019. Despite rigorous containment and quarantine efforts, the incidence of COVID-19 continues to expand, causing explosive outbreaks in more than 160 countries with waves of morbidity and fatality, leading to significant public health problems. In the past 20 years, two additional epidemics caused by CoVs have occurred: severe acute respiratory syndrome-CoV, which has caused a large-scale epidemic in China and 24 other countries; and respiratory syndrome-CoV of the Middle East in Saudi Arabia, which continues to cause sporadic cases. All of these viruses affect the lower respiratory tract and manifest as pneumonia in humans, but the novel SARS-Cov-2 appears to be more contagious and has spread more rapidly worldwide. This mini-review focuses on the cellular immune response to COVID-19 in human subjects, compared to other clinically relevant coronaviruses to evaluate its role in the control of infection and pathogenesis and accelerate the development of a preventive vaccine or immune therapies.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #688845
Database	COVID19

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Article ; Online: Cell-Mediated Immune Responses to COVID-19 Infection

Guihot, Amélie / Litvinova, Elena / Autran, Brigitte / Debré, Patrice / Vieillard, Vincent

ISSN: 1664-3224 ; EISSN: 1664-3224 ; Frontiers in Immunology ; https://hal.sorbonne-universite.fr/hal-02935339 ; Frontiers in Immunology, Frontiers, 2020, 11, pp.1662. ⟨10.3389/fimmu.2020.01662⟩

2020

Abstract: International audience ... An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV), subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan City (China) in December 2019. Despite rigorous containment and ... ...

Abstract	International audience An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV), subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan City (China) in December 2019. Despite rigorous containment and quarantine efforts, the incidence of COVID-19 continues to expand, causing explosive outbreaks in more than 160 countries with waves of morbidity and fatality, leading to significant public health problems. In the past 20 years, two additional epidemics caused by CoVs have occurred: severe acute respiratory syndrome-CoV, which has caused a large-scale epidemic in China and 24 other countries; and respiratory syndrome-CoV of the Middle East in Saudi Arabia, which continues to cause sporadic cases. All of these viruses affect the lower respiratory tract and manifest as pneumonia in humans, but the novel SARS-Cov-2 appears to be more contagious and has spread more rapidly worldwide. This mini-review focuses on the cellular immune response to COVID-19 in human subjects, compared to other clinically relevant coronaviruses to evaluate its role in the control of infection and pathogenesis and accelerate the development of a preventive vaccine or immune therapies.
Keywords	COVID-19 ; SARS - CoV-2 ; adaptive immunity ; coronavirus ; innate immunity ; [SDV]Life Sciences [q-bio] ; covid19
Subject code	950
Language	English
Publishing date	2020-07-03
Publisher	HAL CCSD
Publishing country	fr
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Cell-Mediated Immune Responses to COVID-19 Infection

Guihot, Amélie / Litvinova, Elena / Autran, Brigitte / Debré, Patrice / Vieillard, Vincent

ISSN: 1664-3224 ; EISSN: 1664-3224 ; Frontiers in Immunology ; https://hal.sorbonne-universite.fr/hal-02935339 ; Frontiers in Immunology, Frontiers, 2020, 11, pp.1662. ⟨10.3389/fimmu.2020.01662⟩

2020

Abstract	International audience An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV), subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan City (China) in December 2019. Despite rigorous containment and quarantine efforts, the incidence of COVID-19 continues to expand, causing explosive outbreaks in more than 160 countries with waves of morbidity and fatality, leading to significant public health problems. In the past 20 years, two additional epidemics caused by CoVs have occurred: severe acute respiratory syndrome-CoV, which has caused a large-scale epidemic in China and 24 other countries; and respiratory syndrome-CoV of the Middle East in Saudi Arabia, which continues to cause sporadic cases. All of these viruses affect the lower respiratory tract and manifest as pneumonia in humans, but the novel SARS-Cov-2 appears to be more contagious and has spread more rapidly worldwide. This mini-review focuses on the cellular immune response to COVID-19 in human subjects, compared to other clinically relevant coronaviruses to evaluate its role in the control of infection and pathogenesis and accelerate the development of a preventive vaccine or immune therapies.
Keywords	COVID-19 ; SARS - CoV-2 ; adaptive immunity ; coronavirus ; innate immunity ; [SDV]Life Sciences [q-bio] ; covid19
Subject code	950
Language	English
Publishing date	2020-07-03
Publisher	HAL CCSD
Publishing country	fr
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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