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  1. Article ; Online: Evaluation of CHROMagar

    Bentz, Meghan L / Le, Ngoc / Min, Brian / Nunnally, Natalie S / Sullivan, Vickie / Tran, Mike / Lockhart, Shawn R / Litvintseva, Ana / Berkow, Elizabeth L / Sexton, D Joseph

    Microbiology spectrum

    2024  Volume 12, Issue 4, Page(s) e0356423

    Abstract: ... ...

    Abstract CHROMagar
    MeSH term(s) Humans ; Candida ; Candida auris ; Candidiasis/diagnosis ; Candidiasis/microbiology ; Culture Media ; Coloring Agents ; Antifungal Agents
    Chemical Substances Culture Media ; Coloring Agents ; Antifungal Agents
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.03564-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Diagnostics to support mycetoma management-Development of two target product profiles.

    Fongwen, Noah / Asiedu, Kingsley B / Bakhiet, Sahar / Bonifaz, Alexandro / Cruz, Israel / Argaw, Daniel / Estrada-Chavez, Guadalupe / Fahal, Ahmed H / Litvintseva, Ana / Marks, Michael / Salinas-Carmona, Mario C / Sow, Doudou / van de Sande, Wendy W J

    Tropical medicine & international health : TM & IH

    2022  Volume 27, Issue 12, Page(s) 1059–1064

    Abstract: Objective: Mycetoma is a neglected tropical disease caused by more than 70 different microorganisms and identified by the WHO as one of the high-priority diseases for developing diagnostic tests. To ensure the production of diagnostic assays for use by ... ...

    Abstract Objective: Mycetoma is a neglected tropical disease caused by more than 70 different microorganisms and identified by the WHO as one of the high-priority diseases for developing diagnostic tests. To ensure the production of diagnostic assays for use by clinical staff in endemic regions, target product profiles (TPPs) were designed.
    Methods: We describe the development of two TPPs: one for a diagnostic test able to identify the causative agent of mycetoma and another that would determine when treatment could be stopped. The TPPs were developed by considering product use, design, performance, product configuration and costs.
    Results: Version 1.0 TPPs for two uses were posted by WHO for a 1-month online public consultation on 25 October 2021, and the final TPP was posted online on 5 May 2022.
    Conclusion: A major difficulty encountered in developing both TPPs was the large number of agents able to cause mycetoma and the lack of specific biomarkers for most of them.
    MeSH term(s) Humans ; Mycetoma/diagnosis ; Mycetoma/drug therapy ; Neglected Diseases/diagnosis ; Biological Assay ; Costs and Cost Analysis ; Referral and Consultation
    Language English
    Publishing date 2022-11-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1314080-2
    ISSN 1365-3156 ; 1360-2276
    ISSN (online) 1365-3156
    ISSN 1360-2276
    DOI 10.1111/tmi.13828
    Database MEDical Literature Analysis and Retrieval System OnLINE

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