Article: Stabilization of labile active ingredients in an oil-water emulsion cosmetics by freeze-drying.
2023 Volume 44, Issue 2, Page(s) 76–79
Abstract: Background: Due to the instability in oil/water emulsion, certain labile active ingredients were often not used in cosmetics.: Objective: The present study has tested the effect of freeze-drying to stabilize an oil/water cosmetic emulsion.: ... ...
Abstract | Background: Due to the instability in oil/water emulsion, certain labile active ingredients were often not used in cosmetics. Objective: The present study has tested the effect of freeze-drying to stabilize an oil/water cosmetic emulsion. Materials and methods: A preliminary freeze-drying process was established at the basis of calorimetric and freeze-drying microscope studies. The stability of labile molecules in the cosmetic emulsion was evaluated at 48 degree C after freeze-drying. Results: The accelerated stability experiment showed that the freeze-dried emulsion retained 90.1% vitamin C after 28 days at 48 degree C, whereas the oil-water emulsion retained only 28.3% vitamin C. The freeze-dried emulsion had significantly less oil oxidation than did the oil-water emulsion. Conclusion: Freeze-drying improved the stability of vitamin C and oily active ingredients in cosmetic emulsions. DOI: 10.54680/fr23210110312. |
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MeSH term(s) | Emulsions/chemistry ; Cryopreservation ; Oils/chemistry ; Freeze Drying ; Ascorbic Acid |
Chemical Substances | Emulsions ; Oils ; Ascorbic Acid (PQ6CK8PD0R) |
Language | English |
Publishing date | 2023-10-26 |
Publishing country | England |
Document type | Journal Article |
ZDB-ID | 756781-9 |
ISSN | 0143-2044 |
ISSN | 0143-2044 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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