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  1. Book ; Online ; E-Book: The Lingzhi mushroom genome

    Liu, Chang

    (Compendium of Plant Genomes)

    2021  

    Abstract: This book becomes an invaluable reference on the genetic resources, genome, genes, chemical compounds, and their therapeutic effects for the Lingzhi mushrooms. It is the first comprehensive compilation of genetic resources, nuclear genome, mitochondrial ... ...

    Author's details Chang Liu, editor
    Series title Compendium of Plant Genomes
    Abstract This book becomes an invaluable reference on the genetic resources, genome, genes, chemical compounds, and their therapeutic effects for the Lingzhi mushrooms. It is the first comprehensive compilation of genetic resources, nuclear genome, mitochondrial genome, genes, noncoding RNAs, such as long intergenic noncoding RNAs, microRNAs, circular RNAs, genes in the biosynthetic pathway, chemical compounds and their therapeutic effects, transformation system for the expression of key genes, a bibliometric analysis to identify the past research work and the future research direction, and a survey of products derived from the Lingzhi mushrooms. Each chapter of this book is written by authors of globally reputed experts on the relevant field who had published high-quality articles in the corresponding subject. The book has 12 chapters and each chapter has a length of approximately ten thousand words, including ten items (tables or figures), about 30–50 references. This book is useful to the students, teachers, and scientists in academia and relevant private companies interested in horticulture, genetics, physiology, molecular genetics, and breeding, in vitro culture and genetic engineering, and structural and functional genomics. This book is also useful to seed and pharmaceutical industries.
    Keywords Bolets comestibles ; Basidiomicets ; Genomes ; Botany ; Genetics ; Biotechnology
    Subject code 581
    Language English
    Size 1 online resource (XVI, 229 p. 103 illus., 83 illus. in color.)
    Edition 1st ed. 2021.
    Publisher Springer
    Publishing place Cham, Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-75710-2 ; 3-030-75709-9 ; 978-3-030-75710-6 ; 978-3-030-75709-0
    DOI 10.1007/978-3-030-75710-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Missbrauch des Beweisantragsrechts im Strafprozess und Missbrauchsabwehr

    Liu, Chang

    (Schriften zum Prozessrecht ; 271)

    2021  

    Series title Schriften zum Prozessrecht ; 271
    Keywords Private / Civil law: general works ; Criminal law & procedure ; Beweisantragsrecht ; Wahrheitsermittlung ; Missbrauch
    Language German
    Size 1 electronic resource (276 pages)
    Publisher Duncker and Humblot
    Publishing place Berlin
    Document type Book ; Online
    Note German
    HBZ-ID HT030382213
    ISBN 9783428181162 ; 3428181166
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: High-Throughput Mass Spectrometry in Drug Discovery

    Liu, Chang / Zhang, Hui

    2023  

    Author's details Chang Liu, Ph.D., is a Staff Research Scientist at SCIEX, a global leader in the design and production of mass spectrometers. He has published extensively on using mass spectrometry in drug discovery and development. Hui Zhang, Ph.D., is the Vice President of Analytical Technologies at Entos, a biotech company focusing on Artificial Intelligence and High-Throughput Experimentation driving drug discovery. He has published widely on mass spectrometry and its pharmaceutical applications through his previous tenure at Pfizer
    Language English
    Size 512 p.
    Publisher John Wiley & Sons Ltd
    Document type Book
    Note PDA Manuell_23
    Format 157 x 235 x 32
    ISBN 9781119678434 ; 1119678439
    Database PDA

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  4. Article ; Online: Analysis of ANS structures and molecular evolution in Rosaceae

    Liu Chang

    BIO Web of Conferences, Vol 59, p

    2023  Volume 01010

    Abstract: Anthocyanidin Synthase (ANS) is a key rate-limiting enzyme involves in the biosynthesis of anthocyanin. Notably, anthocyanin contents of Rosaceae have a significant impact on its economic value as major economic crops. Thus, the role of ANS in the ... ...

    Abstract Anthocyanidin Synthase (ANS) is a key rate-limiting enzyme involves in the biosynthesis of anthocyanin. Notably, anthocyanin contents of Rosaceae have a significant impact on its economic value as major economic crops. Thus, the role of ANS in the regulation of anthocyanin contents in the Rosaceae family is worthy of investigation. Since the characterizations and expression pattern of ANS in the Rosaceae family are largely unknown so far, a systematic analysis is required to extend current understanding. Using the bioinformatics methods, we performed comprehensive bioinformatic analysis for the ANS amino acid sequences of 11 major Rosaceae species, which shared a high degree of similarity and identity, and also clustered closely in the phylogenetic analysis. Through homology modeling, 11 Rosaceae species ANS were divided into two groups: one group with similar structures to AtANS and the other with similar structures to AtACO2. Further protein-ligand docking showed that most ANS might be involved in the anthocyanin synthesis. This study found that ANS from 11 Rosaceae species shared highly similar characteristics, protein structures, and binding characteristics, helping increase the understanding of ANS evolution in Rosaceae fruits and providing supports for studies in the regulation of anthocyanin biosynthesis of Rosaceae plants.
    Keywords Microbiology ; QR1-502 ; Physiology ; QP1-981 ; Zoology ; QL1-991
    Subject code 580
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: High-throughput MS for intact protein analysis.

    Liu, Chang

    Bioanalysis

    2023  Volume 15, Issue 16, Page(s) 1017–1019

    MeSH term(s) Mass Spectrometry ; Amino Acid Sequence ; Protein Processing, Post-Translational
    Language English
    Publishing date 2023-08-16
    Publishing country England
    Document type Editorial
    ISSN 1757-6199
    ISSN (online) 1757-6199
    DOI 10.4155/bio-2023-0139
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Impact of Global Warming on China’s Agricultural Production

    Liu Chang

    E3S Web of Conferences, Vol 352, p

    2022  Volume 03024

    Abstract: Global warming has had an important impact on China’s agricultural production, especially the intensified uneven distribution of water and heat resources and the increased frequency of extreme weather, resulting in a significant increase in the risk of ... ...

    Abstract Global warming has had an important impact on China’s agricultural production, especially the intensified uneven distribution of water and heat resources and the increased frequency of extreme weather, resulting in a significant increase in the risk of agricultural production. Alleviating a series of negative effects of climate warming on agricultural production has always been the focus of governments and scholars, and it is also the basis of realizing agricultural sustainable development. This paper summarizes the impact of climate warming on China’s agricultural production from five aspects: agricultural planting system and structural layout, agricultural diseases and pests, agricultural management, agricultural ecosystem and agricultural production potential. Based on the above specific impacts, the urgent problems faced by China's agricultural production are pointed out, and the countermeasures to reduce the impact of climate warming are put forward from the aspects of policy, technology, research and cooperation, in order to provide references for other governments to deal with the negative impact of global warming, and promote the sustainable development of agriculture.
    Keywords climate change ; hydrothermal resources ; extreme weather ; coping strategies ; sustainable development ; Environmental sciences ; GE1-350
    Subject code 306
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Book ; Online: Cognitive Processes in Individual and Collective Creativity: A Cross-Cultural Perspective

    Liu, Chang / John Ball, Linden / Long, Haiying / Shen, Wangbing

    2019  

    Keywords Science: general issues ; Psychology ; cognitive processes ; collective creativity ; individual creativity ; cross-cultural ; insight problem solving
    Size 1 electronic resource (227 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230738
    ISBN 9782889632817 ; 2889632814
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  8. Article ; Online: Personalized Recommendation Algorithm for Movie Data Combining Rating Matrix and User Subjective Preference.

    Liu, Chang

    Computational intelligence and neuroscience

    2022  Volume 2022, Page(s) 2970514

    Abstract: The film industry has also caught the fast train of Internet development. Various movie resources have come into view. Users need to spend a lot of time searching for movies they are interested in. This method wastes time and is very bad. The article ... ...

    Abstract The film industry has also caught the fast train of Internet development. Various movie resources have come into view. Users need to spend a lot of time searching for movies they are interested in. This method wastes time and is very bad. The article proposes an NMF personalized movie recommendation algorithm, which can recommend movies to users based on their historical behavior and preference. The research results of the article show the following: (1) the experiment counts movie reviews of different users in the same time span. The results show that 48.42% of users have only commented on a movie once, 79.76% of users have posted less than or equal to 5 comments, and 89.92% of user reviews have posted less than or equal to 10 times. (2) In the comparative experiments of the NMF algorithm in different dimensions, the effect of the NMF-E algorithm is much better than that of the NMF-A algorithm. The accuracy, recall, and
    MeSH term(s) Algorithms ; Humans ; Industry ; Motion Pictures
    Language English
    Publishing date 2022-08-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2388208-6
    ISSN 1687-5273 ; 1687-5273
    ISSN (online) 1687-5273
    ISSN 1687-5273
    DOI 10.1155/2022/2970514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Acoustic ejection mass spectrometry: fundamentals and applications in high-throughput drug discovery.

    Liu, Chang

    Expert opinion on drug discovery

    2022  Volume 17, Issue 7, Page(s) 775–787

    Abstract: Introduction: Acoustic ejection mass spectrometry (AEMS) is an electrospray ionization-mass spectrometry (ESI-MS) based analytical platform that provides high analytical throughput and data quality. It has been applied in numerous drug discovery ... ...

    Abstract Introduction: Acoustic ejection mass spectrometry (AEMS) is an electrospray ionization-mass spectrometry (ESI-MS) based analytical platform that provides high analytical throughput and data quality. It has been applied in numerous drug discovery workflows, such as high-throughput screening (HTS), absorption, distribution, metabolism, and excretion (ADME) profiling, pharmacokinetics (PK) analysis, compound quality control (QC), and the high throughput readout of medical chemistry samples.
    Areas covered: This paper introduces the working principle of AEMS technology. The analytical performance, system tuning and method development workflows, and representative applications on high-throughput drug discovery assays are introduced.
    Expert opinion: The fast sample readout speed, high reproducibility, wide compound coverage, minimum carryover, and the tolerance to complex sample matrices of AEMS have demonstrated its advantages over other technologies in this field, with broad applicability to a diverse range of drug discovery workflows. However, the current platform still has challenges for some assays due to having less sensitivity compared with liquid chromatography-mass spectrometry (LC-MS), and the lack of chromatographic separation for isomeric interferences. Despite the remaining hurdles, AEMS is becoming an attractive high-throughput analytical platform in drug discovery. Additional system developments would enable its further adoption in the future.
    MeSH term(s) Acoustics ; Chromatography, Liquid ; Drug Discovery/methods ; High-Throughput Screening Assays/methods ; Humans ; Mass Spectrometry/methods ; Reproducibility of Results
    Language English
    Publishing date 2022-05-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2259618-5
    ISSN 1746-045X ; 1746-0441
    ISSN (online) 1746-045X
    ISSN 1746-0441
    DOI 10.1080/17460441.2022.2084069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Research on the Development Strategy of Fresh Food E-commerce Enterprises under COVID-19-Taking Ding Dong as an Example

    Liu Chang

    E3S Web of Conferences, Vol 275, p

    2021  Volume 01035

    Abstract: During the period of the COVID-19 epidemic situation, many industries and enterprises fell into crisis due to the negative impact they have suffered. However, some industries have enjoyed a wave of dividends of epidemic situation and developed during the ...

    Abstract During the period of the COVID-19 epidemic situation, many industries and enterprises fell into crisis due to the negative impact they have suffered. However, some industries have enjoyed a wave of dividends of epidemic situation and developed during the fight against the epidemic situation. Fresh e-commerce industry is one of them. Taking Ding Dong as an example, this paper comprehensively analyzes the reasons for its success from PEST, SWOT, market behavior, organization strategy and other aspects, and gives suggestions on highlighting platform advantages, improving service quality and improving cold chain logistics system, so as to enhance the sustainable development ability of fresh food e-commerce enterprises under the epidemic situation.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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