Article: NCOA5, a molecular link between type 2 diabetes and liver cancer.
Hepatobiliary surgery and nutrition
2014 Volume 3, Issue 3, Page(s) 106–108
Abstract: It is reported that nuclear receptor co-activator 5 (NCOA5) is a possible susceptibility gene to both type 2 diabetes (T2D) and hepatocellular carcinoma (HCC). The link between these two diseases is an important area of study with the growing prevalence ... ...
| Abstract | It is reported that nuclear receptor co-activator 5 (NCOA5) is a possible susceptibility gene to both type 2 diabetes (T2D) and hepatocellular carcinoma (HCC). The link between these two diseases is an important area of study with the growing prevalence of T2D. Thus, discovery of a genetic link may have great impact on the field. The group used NCOA5 (+/-) mice to observe the effects of the gene's haploinsufficiency on the symptoms of T2D and HCC and claimed NCOA5's regulation of IL-6 in the pathogenesis of the diseases. |
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| Language | English |
| Publishing date | 2014-06-26 |
| Publishing country | China (Republic : 1949- ) |
| Document type | Journal Article |
| ZDB-ID | 2812398-0 |
| ISSN | 2304-389X ; 2304-3881 |
| ISSN (online) | 2304-389X |
| ISSN | 2304-3881 |
| DOI | 10.3978/j.issn.2304-3881.2014.04.02 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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