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Article ; Online: Performance evolution of prestressing anchor bars in corrosive environments experimental study.

Liu, Dandan / Chen, An

2023 Volume 13, Issue 1, Page(s) 9004

Abstract: In order to explore the performance evolution of prestressed anchor cables in corrosive environment, the corrosion immersion and corrosion damage performance tests of prestressed anchor bars in corrosive environment were carried out indoors. Based on the ...

Abstract	In order to explore the performance evolution of prestressed anchor cables in corrosive environment, the corrosion immersion and corrosion damage performance tests of prestressed anchor bars in corrosive environment were carried out indoors. Based on the experimental results, the effects of stress level, pH and time on the corrosion process of prestressing anchor bars, the amount of corrosion per unit length and the change of mechanical properties were analyzed. It was found that the greater the stress level in the three corrosive media, the more severe the corrosion of the anchor bars, especially in acidic solutions; at the beginning of corrosion, prestressing anchor bars corrode fastest in neutral solution, followed by acidic and slowest in alkaline, with the continuation of corrosion, the degree of corrosion damage to anchor bars by acidic solution is more obvious; The corrosion damage of anchor tendons reflected by the corrosion amount per unit length is uniform corrosion, and local corrosion will aggravate the degree of corrosion damage of prestressing anchor tendons; The longer the corrosion time, the more serious the corrosion of anchor bars, and the 2 mechanical indexes of anchor bar elongation and fracture load have a significant decreasing trend.
Language	English
Publishing date	2023-06-02
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-35577-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Chronic disease and multimorbidity in the Chinese older adults' population and their impact on daily living ability: a cross-sectional study of the Chinese Longitudinal Healthy Longevity Survey (CLHLS).

Chen, Ye / Ji, Huixia / Shen, Yang / Liu, Dandan

Archives of public health = Archives belges de sante publique

2024 Volume 82, Issue 1, Page(s) 17

Abstract: Background: Owing to an increase in life expectancy, it is common for the older adults to suffer from chronic diseases that can result in disability and a low quality of life. This study aimed to explore the influence of chronic diseases and ... ...

Abstract	Background: Owing to an increase in life expectancy, it is common for the older adults to suffer from chronic diseases that can result in disability and a low quality of life. This study aimed to explore the influence of chronic diseases and multimorbidities on activities of daily living (ADLs) and instrumental ADLs (IADLs) in an older Chinese population. Methods: Based on the Chinese Longitudinal Healthy Longevity Survey (2018), 9,155 older adults aged 65 years and above were included in the study. A self-administered questionnaire was used to collect information on demographic characteristics, chronic diseases, ADLs, and IADLs. The impact of factors affecting ADL and IADL impairment in older adults was analysed using binary logistic regression. Results: In total, 66.3% participants had chronic diseases. Hypertension, heart disease, arthritis, diabetes and cerebrovascular disease were among the top chronic diseases. Of these, 33.7% participants had multimorbidities. The most common combination of the two chronic diseases was hypertension and heart disease (11.2%), whereas the most common combination of the three chronic diseases was hypertension, heart disease, and diabetes (3.18%). After categorising the older adults into four age groups, dementia, visual impairment, and hearing impairment were found to be more prevalent with increasing age. The prevalence of hypertension, heart disease, cerebrovascular disease, gastrointestinal ulcers, arthritis and chronic nephritis gradually increased with age until the age of 75 years, peaked in the 75-84 years age group, and then showed a decreasing trend with age. Multimorbidity prevalence followed a similar pattern. Regression analysis indicated that the increase in age group and the number of chronic diseases independently correlated with impairments in ADL as well as IADL. Additionally, gender, physical activity, educational background, obesity, depressive symptoms, and falls also had an impact on ADLs or IADLs. Conclusion: Chronic diseases and multimorbidities are common in older adults, and it is important to note that aging, multimorbidity, obesity, and unhealthy lifestyle choices may interfere with ADLs or IADLs in older adults. Therefore, it is imperative that primary healthcare providers pay special attention to older adults and improve screening for multimorbidity and follow-up needs.
Language	English
Publishing date	2024-02-01
Publishing country	England
Document type	Journal Article
ZDB-ID	1117688-x
ISSN	2049-3258 ; 0778-7367 ; 0003-9578
ISSN (online)	2049-3258
ISSN	0778-7367 ; 0003-9578
DOI	10.1186/s13690-024-01243-2
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Article ; Online: Rice varietal resistance to the vector Sogatella furcifera hinders transmission of Southern rice black-streaked dwarf virus.

Liu, Dandan / Zhong, Yuqi / Li, Zhengxi / Hou, Maolin

Pest management science

2024

Abstract: Background: The Southern rice black-streaked dwarf virus (SRBSDV) transmitted by Sogatella furcifera constitutes a threat to sustainable rice production. However, most rice varieties are highly vulnerable to SRBSDV, whereas the occurrence of the viral ... ...

Abstract	Background: The Southern rice black-streaked dwarf virus (SRBSDV) transmitted by Sogatella furcifera constitutes a threat to sustainable rice production. However, most rice varieties are highly vulnerable to SRBSDV, whereas the occurrence of the viral disease varies significantly under field conditions. This study aimed to evaluate the potential of rice varietal resistance to S. furcifera in reducing SRBSDV transmission. Results: Among the five rice varieties, Zhongzheyou8 and Deyou108 exhibited high resistance to S. furcifera, Baixiangnuo33 was susceptible, and TN1 and Diantun502 were highly susceptible. The S. furcifera generally showed non-preference for and low feeding on the Zhongzheyou8 and Deyou108 plants, which may explain the resistance of these varieties to S. furcifera. Transmission of SRBSDV by S. furcifera was significantly impaired on the resistant varieties, both inoculation and acquisition rates were much lower on Zhongzheyou8 than on TN1. The short durations of S. furcifera salivation and phloem-related activities and the low S. furcifera feeding amount may explain the reduced SRBSDV inoculation and acquisition rates associated with Zhongzheyou8. Spearman's rank correlation revealed a significant negative correlation between S. furcifera resistance and SRBSDV transmission among the tested varieties. Conclusion: The results indicate that rice varietal resistance to the vector S. furcifera hinders SRBSDV transmission, which is largely associated with the host plant selection and feeding behaviors of the vector. The current findings shed light on the management of the SRBSDV viral disease through incorporation of S. furcifera resistant rice varieties in the management protocol. © 2024 Society of Chemical Industry.
Language	English
Publishing date	2024-03-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2001705-4
ISSN	1526-4998 ; 1526-498X
ISSN (online)	1526-4998
ISSN	1526-498X
DOI	10.1002/ps.8072
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Article: Clinical Manifestation, mNGS Based Diagnosis and Treatment of Pulmonary Mucormycosis with

Cheng, Xuesong / Li, Tianyu / Wu, Fengsheng / Liu, Dandan

Infection and drug resistance

2024 Volume 17, Page(s) 1379–1384

Abstract: Pulmonary mucormycosis is a severe and often fatal disease that commonly affects patients with underlying conditions, such as diabetes. Early diagnosis and appropriate treatment are crucial for improving survival rates. However, clinical diagnosis ... ...

Abstract	Pulmonary mucormycosis is a severe and often fatal disease that commonly affects patients with underlying conditions, such as diabetes. Early diagnosis and appropriate treatment are crucial for improving survival rates. However, clinical diagnosis remains challenging due to difficulty in obtaining etiological evidence. In this particular case, the patient presented with a cough-producing bloody sputum, and a chest CT revealed lesions in the right upper lobe of the lung. The patient was ultimately diagnosed with pulmonary mucormycosis caused by
Language	English
Publishing date	2024-04-08
Publishing country	New Zealand
Document type	Case Reports
ZDB-ID	2494856-1
ISSN	1178-6973
ISSN	1178-6973
DOI	10.2147/IDR.S454029
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Article ; Online: Trends in use of composite endpoints in clinical trials: A comparison between acute heart failure trials and COVID-19 trials.

Shi, Lan / Lindsell, Christopher John / Liu, Dandan

Journal of clinical and translational science

2024 Volume 8, Issue 1, Page(s) e55

Abstract: Composite endpoints can encode multiple pieces of information and are increasingly adopted in clinical trials. Advocacy for using composite endpoints began decades ago in cardiovascular trials, leading to incorporation of patient-oriented outcomes and ... ...

Abstract	Composite endpoints can encode multiple pieces of information and are increasingly adopted in clinical trials. Advocacy for using composite endpoints began decades ago in cardiovascular trials, leading to incorporation of patient-oriented outcomes and consideration of a hierarchical ranking system. The use of composite endpoints in coronavirus disease (COVID-19) trials has evolved similarly. We conducted a literature review to investigate the use of composite endpoints in acute heart failure and COVID-19 clinical trials. The results showed more frequent use of patient-oriented outcomes and ordinal composite endpoints in COVID-19 trials, which might be driven by global consensus on a set of common outcome measures.
Language	English
Publishing date	2024-03-08
Publishing country	England
Document type	Journal Article
ISSN	2059-8661
ISSN (online)	2059-8661
DOI	10.1017/cts.2024.492
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Article ; Online: Highly active Cu-MFI catalyst for conversion of furfuryl alcohol to pentanediols

Dai Dengfeng / Liu Dandan / Liu Yunqi

E3S Web of Conferences, Vol 375, p

2023 Volume 03007

Abstract: It is of great significance to use biomass-based furfuryl alcohol to produce oxygenated chemicals to replace petroleum-based chemicals. In this paper, a series of bifunctional Cu-MFI catalysts were developed, and the properties of biomass-based furfuryl ... ...

Abstract	It is of great significance to use biomass-based furfuryl alcohol to produce oxygenated chemicals to replace petroleum-based chemicals. In this paper, a series of bifunctional Cu-MFI catalysts were developed, and the properties of biomass-based furfuryl alcohol to pentanediol, including 1,5-pentanediol and 1,2 pentanediol, were investigated. These catalysts were synthesized by ammonia evaporation method by loading copper nanoparticles on MFI molecular sieve systems with different silicon aluminum ratios. Among them, Cu-MFI (60)-AE catalyst containing abundantly Brønsted acid protons shows excellent performance, achieving 99.7% furfuryl alcohol conversion and 91% pentanediol selectivity under mild reaction conditions. The high catalytic activity can be attributed to the highly dispersed Cu species and Brønsted acid protons. Brønsted acid protons play a decisive role in the highly selective formation of 1,5-PDO. This paper can develop an economical and feasible path for converting furfuryl alcohol into high value-added fine chemicals.
Keywords	Environmental sciences ; GE1-350
Subject code	540
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: An infant with congenital heart defects and proteinuria: a case report.

Liu, Dandan / Wang, Yafeng

BMC pediatrics

2022 Volume 22, Issue 1, Page(s) 636

Abstract: Background: Branchio-Oto-Renal (BOR) Syndrome is a rare autosomal disorder with a wide variety of clinical manifestations and a high degree of heterogeneity. Typical clinical manifestations of BOR syndrome include deafness, preauricular fistula, ... ...

Abstract	Background: Branchio-Oto-Renal (BOR) Syndrome is a rare autosomal disorder with a wide variety of clinical manifestations and a high degree of heterogeneity. Typical clinical manifestations of BOR syndrome include deafness, preauricular fistula, abnormal gill slits, and renal malformations. However, atypical phenotypes such as congenital hip dysplasia, congenital heart anomaly or facial nerve paresis are rare in BOR syndrome, and this might be easily misdiagnosed with other congenital disorders. Case presentation: We report a 5-month-old boy of BOR syndrome with "congenital heart defects and proteinuria" as clinical features. Initially, as this case mainly presented with symptoms of recurrent respiratory infections and was found to be with congenital heart disease and proteinuria at the local hospital, but he only was diagnosed with congenital heart disease combined with pulmonary infection and anti-infective and supportive treatment was given. Subsequently, during the physical examination at our hospital, left side preauricular pit and branchial fistulae on the right neck were found. Subsequent evaluation of auditory brainstem response and distortion product otoacoustic emission were revealed sensorineural hearing impairment. Results of renal ultrasonography showed small kidneys. Genetic analysis revealed a microdeletion at chromosome 8q13.2-q13.3 encompassing EYA1 gene, this patient was finally diagnosed with BOR syndrome. Then, this patient received transcatheter patent ductus arteriosus closure and hearing aid treatment. Proteinuria, renal function and hearing ability are monitoring by nephrologist and otologist. The patient is currently being followed up until 3 months after discharge and his condition is stable. Conclusion: Careful physical examination, detailed history and the implementation of diagnostic laboratory tests can reduce the incidence of misdiagnosis. Genetic sequencing analysis of patients is a key guide to the differential diagnosis of BOR syndrome.
MeSH term(s)	Male ; Humans ; Branchio-Oto-Renal Syndrome/complications ; Branchio-Oto-Renal Syndrome/diagnosis ; Branchio-Oto-Renal Syndrome/genetics ; Pedigree ; Phenotype ; Proteinuria ; Heart Defects, Congenital/complications ; Heart Defects, Congenital/diagnosis ; Heart Defects, Congenital/genetics
Language	English
Publishing date	2022-11-04
Publishing country	England
Document type	Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041342-7
ISSN	1471-2431 ; 1471-2431
ISSN (online)	1471-2431
ISSN	1471-2431
DOI	10.1186/s12887-022-03705-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Analysis of the effect of nursing care based on action research method on the prevention of postoperative lymphedema in breast cancer patients.

Yang, Weijuan / Yang, Li / Mao, Shuangwei / Liu, Dandan / Wang, Lili

Medicine

2024 Volume 102, Issue 52, Page(s) e36743

Abstract: Rationale: In recent times, the pervasive adoption of the action research method has garnered substantial attention both domestically and internationally. Its integration has traversed various domains of nursing research, nursing education, and nursing ... ...

Abstract	Rationale: In recent times, the pervasive adoption of the action research method has garnered substantial attention both domestically and internationally. Its integration has traversed various domains of nursing research, nursing education, and nursing practice, yielding commendable outcomes. However, a notable gap persists, as this method remains untapped in the realm of nursing care concerning the prevention of postoperative lymphedema in breast cancer patients. Diagnosis: To employ the action research methodology in the context of patients undergoing axillary lymph node dissection surgery for breast cancer, aiming to investigate its impact on mitigating postoperative lymphedema and assessing its influence on the patient's quality of life, as well as levels of anxiety and depression postoperatively. Intervention: The study focused on breast cancer patients admitted to our hospital from January 2022 to December 2022. Among them, 44 patients from January to June constituted the control group, while 44 patients from July to December comprised the observation group. Conventional nursing measures were applied to the control group, whereas the observation group received nursing interventions rooted in the action research method. A comparative analysis was conducted between the 2 groups, assessing the incidence of postoperative lymphedema, daily life ability, as well as levels of anxiety and depression. Outcomes: The prevalence of edema was notably reduced in the observation group (20.93%) compared to the control group (42.22%), with a statistically significant difference. Throughout the study, patients in both groups exhibited increased Barthel Index Scale scores from the study's initiation, and the scores for the observation group surpassed those of the control group, reaching statistical significance (P < .05). Furthermore, by the study's conclusion, anxiety and depression scores for patients in both groups were diminished compared to the study's commencement, and the observation group demonstrated significantly lower scores in anxiety and depression compared to the control group (P < .05). Lessons: The implementation of nursing care grounded in the action research methodology exhibits a capacity to diminish both the occurrence and intensity of postoperative lymphedema in breast cancer patients. Concurrently, it enhances the patients' daily life functionality and mitigates symptoms of anxiety and depression.
MeSH term(s)	Humans ; Female ; Breast Neoplasms/surgery ; Breast Neoplasms/complications ; Quality of Life ; Research Design ; Lymphedema/etiology ; Lymphedema/prevention & control ; Lymph Node Excision/adverse effects ; Lymph Node Excision/methods
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000036743
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Enhancing Generalizability in Protein-Ligand Binding Affinity Prediction with Multimodal Contrastive Learning.

Luo, Ding / Liu, Dandan / Qu, Xiaoyang / Dong, Lina / Wang, Binju

Journal of chemical information and modeling

2024 Volume 64, Issue 6, Page(s) 1892–1906

Abstract: Improving the generalization ability of scoring functions remains a major challenge in protein-ligand binding affinity prediction. Many machine learning methods are limited by their reliance on single-modal representations, hindering a comprehensive ... ...

Abstract	Improving the generalization ability of scoring functions remains a major challenge in protein-ligand binding affinity prediction. Many machine learning methods are limited by their reliance on single-modal representations, hindering a comprehensive understanding of protein-ligand interactions. We introduce a graph-neural-network-based scoring function that utilizes a triplet contrastive learning loss to improve protein-ligand representations. In this model, three-dimensional complex representations and the fusion of two-dimensional ligand and coarse-grained pocket representations converge while distancing from decoy representations in latent space. After rigorous validation on multiple external data sets, our model exhibits commendable generalization capabilities compared to those of other deep learning-based scoring functions, marking it as a promising tool in the realm of drug discovery. In the future, our training framework can be extended to other biophysical- and biochemical-related problems such as protein-protein interaction and protein mutation prediction.
MeSH term(s)	Ligands ; Drug Discovery ; Machine Learning ; Mutation ; Neural Networks, Computer
Chemical Substances	Ligands
Language	English
Publishing date	2024-03-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	190019-5
ISSN	1549-960X ; 0095-2338
ISSN (online)	1549-960X
ISSN	0095-2338
DOI	10.1021/acs.jcim.3c01961
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Article ; Online: Eudragit S100 coated nanodiamond-based nanoparticles as an oral chemo-photothermal delivery system for local treatment of colon cancer.

Su, Yupei / Pan, Hao / Wang, Jiahui / Liu, Dandan / Pan, Weisan

Colloids and surfaces. B, Biointerfaces

2024 Volume 237, Page(s) 113849

Abstract: Oral colonic nano-drug delivery system has received more and more attention in the treatment of colon cancer due to local precision treatment and reduction of drug system distribution. However, the complex and harsh gastrointestinal environment and the ... ...

Abstract	Oral colonic nano-drug delivery system has received more and more attention in the treatment of colon cancer due to local precision treatment and reduction of drug system distribution. However, the complex and harsh gastrointestinal environment and the retention of nanoparticles in the colon limit its development. To this end, we designed Eudragit S100 (ES) coated nanoparticles (ES@PND-PEG-TPP/DOX). Polydopamine coated nanodiamond (PND) was modified with amino-functionalized polyethylene glycol (NH
MeSH term(s)	Humans ; Nanodiamonds ; Phototherapy/methods ; Nanoparticles ; Doxorubicin/pharmacology ; Colonic Neoplasms/drug therapy ; Cell Line, Tumor ; Polymethacrylic Acids
Chemical Substances	Nanodiamonds ; methylmethacrylate-methacrylic acid copolymer (25086-15-1) ; Doxorubicin (80168379AG) ; Polymethacrylic Acids
Language	English
Publishing date	2024-03-13
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1500523-9
ISSN	1873-4367 ; 0927-7765
ISSN (online)	1873-4367
ISSN	0927-7765
DOI	10.1016/j.colsurfb.2024.113849
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