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  1. Article: [Diagnostic value of apparent diffusion coefficient histograms using multiplexed sensitivity encoding diffusion-weighted imaging for distinguishing nasopharyngeal carcinoma from benign hyperplasia].

    Meng, T B / Fu, J / Liu, H B / Liu, H M / He, H Q / Ke, L R / Xie, C M

    Zhonghua yi xue za zhi

    2024  Volume 104, Issue 6, Page(s) 445–449

    Abstract: The data of 115 patients with nasopharyngeal masses (78 males and 37 females) aged between 12 and 78 years at the Sun Yat-sen University Cancer Center from May 2022 to July 2023 were retrospectively reviewed, including 70 cases of nasopharyngeal ... ...

    Abstract The data of 115 patients with nasopharyngeal masses (78 males and 37 females) aged between 12 and 78 years at the Sun Yat-sen University Cancer Center from May 2022 to July 2023 were retrospectively reviewed, including 70 cases of nasopharyngeal carcinoma and 45 cases of benign hyperplasia. The mean, median, and percentiles (10
    MeSH term(s) Humans ; Male ; Female ; Child ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Aged ; Nasopharyngeal Carcinoma ; Hyperplasia ; Retrospective Studies ; Alprostadil ; Diffusion Magnetic Resonance Imaging/methods ; ROC Curve ; Nasopharyngeal Neoplasms ; Sensitivity and Specificity ; Diagnosis, Differential
    Chemical Substances Alprostadil (F5TD010360)
    Language Chinese
    Publishing date 2024-02-07
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20230811-00201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [A case report of splenectomy for type 1 Gaucher disease combined with splenic infarction].

    Hu, W Y / Liu, H B / Li, L / Lai, L L

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2021  Volume 29, Issue 6, Page(s) 583–584

    MeSH term(s) Gaucher Disease/complications ; Gaucher Disease/surgery ; Humans ; Splenectomy ; Splenic Infarction/etiology ; Splenic Infarction/surgery
    Language Chinese
    Publishing date 2021-08-17
    Publishing country China
    Document type Case Reports ; Journal Article
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.cn501113-20200318-00123
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The neuroprotective effects of Galectin-1 on Parkinson's Disease via regulation of Nrf2 expression.

    Liu, H-B / Li, Q-Y / Zhang, X-D / Shi, Y / Li, J-Y

    European review for medical and pharmacological sciences

    2022  Volume 26, Issue 2, Page(s) 623–636

    Abstract: Objective: Parkinson's disease (PD) is one of the neurodegenerative diseases. Galectin-1 (Gal-1) is expressed in the central nervous system. Our study sought to explore the neuroprotective effect of Gal-1 in 1‑methyl‑4‑phenyl pyridine ion (MPP+)-induced ...

    Abstract Objective: Parkinson's disease (PD) is one of the neurodegenerative diseases. Galectin-1 (Gal-1) is expressed in the central nervous system. Our study sought to explore the neuroprotective effect of Gal-1 in 1‑methyl‑4‑phenyl pyridine ion (MPP+)-induced cytotoxicity on SH-SY5Y cells.
    Materials and methods: SH-SY5Y cells were cultured in vitro, pretreated with Gal-1, and then exposed to MPP+. Thereafter, the generation of reactive oxygen species (ROS) in SH-SY5Y cells was investigated. The effects of Gal-1 on DNA breakage, cell damage (release of lactate dehydrogenase (LDH)), viability, and apoptosis in SH-SY5Y cells were examined by comet assay, LDH assay, WST-1 assay, and flow cytometry, respectively. Additionally, the regulatory effect of Gal-1 on Nrf2 expression was examined by western blot. Zebrafish embryos were pretreated with Gal-1 and then exposed to MPP+. The locomotor ability of zebrafish larvae was then investigated.
    Results: MPP+ induced the production of ROS in cells, which can be alleviated by pretreatment with Gal-1. Gal-1 protected cells from MPP+-induced cytotoxicity by preventing DNA breakage and cell injury. Gal-1 inhibited apoptosis in SH-SY5Y cells. The neuroprotective effect of Gal-1 could be abolished when Nrf2 expression knockdown. Moreover, exposure to MPP+ decreased the locomotor activity of zebrafish, which was attenuated by pretreatment with Gal-1.
    Conclusions: Our study demonstrated that the administration of Gal-1 could protect neurons from cellular stress by preventing apoptosis and eliminating ROS. Moreover, the neuroprotective effect of Gal-1 in neuronal cells could be related to the activation of Nrf2 expression. Therefore, Gal-1 could be a promising strategy for treating PD.
    MeSH term(s) 1-Methyl-4-phenylpyridinium/toxicity ; Animals ; Apoptosis ; Cell Line, Tumor ; Cell Survival ; Galectin 1/genetics ; Galectin 1/metabolism ; Galectin 1/pharmacology ; NF-E2-Related Factor 2/metabolism ; Neuroprotective Agents/pharmacology ; Oxidative Stress ; Parkinson Disease/drug therapy ; Parkinson Disease/genetics ; Reactive Oxygen Species/metabolism ; Zebrafish/metabolism
    Chemical Substances Galectin 1 ; NF-E2-Related Factor 2 ; Neuroprotective Agents ; Reactive Oxygen Species ; 1-Methyl-4-phenylpyridinium (R865A5OY8J)
    Language English
    Publishing date 2022-02-03
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202201_27889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1887: Show issues Location:
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  4. Article: [Reseach progress on evaluating methods of physical labor load].

    Zhang, Y / Huang, L / Liu, H B

    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

    2019  Volume 37, Issue 4, Page(s) 317–321

    MeSH term(s) Humans ; Physical Exertion ; Research/trends ; Research Design ; Workload
    Language Chinese
    Publishing date 2019-06-08
    Publishing country China
    Document type Journal Article
    ISSN 1001-9391
    ISSN 1001-9391
    DOI 10.3760/cma.j.issn.1001-9391.2019.04.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Conference proceedings: Keynote Lecture 1 “Using complementary approaches for antimicrobial discovery, biosynthesis and interrogation of microbial strain libraries”

    Bewley, C / Ohlemacher, S / Zhao, G / Rajwani, R / Liu, H B

    Planta Medica

    2022  Volume 88, Issue 15

    Event/congress GA - 70th Annual Meeting 2022, Thessaloniki, Greece, 2022-08-28
    Language English
    Publishing date 2022-12-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 123545-x
    ISSN 1439-0221 ; 0032-0943
    ISSN (online) 1439-0221
    ISSN 0032-0943
    DOI 10.1055/s-0042-1758903
    Database Thieme publisher's database

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  6. Article: [Laryngeal angiosarcoma: a case report].

    Li, C H / Liu, X / Liu, H B / Liao, B / Luo, G

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2020  Volume 55, Issue 4, Page(s) 406–407

    MeSH term(s) Hemangiosarcoma/pathology ; Humans ; Laryngeal Neoplasms/pathology ; Larynx/pathology
    Language Chinese
    Publishing date 2020-04-19
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    DOI 10.3760/cma.j.cn115330-20190729-00472
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3733: Show issues Location:
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  7. Article: [Clinical features and long-term prognosis of diabetic patients with low or intermediate complexity coronary artery disease post percutaneous coronary intervention].

    Chen, Y / Zhu, P / Xu, J J / Song, Y / Jiang, L / Gao, L J / Chen, J / Song, L / Gao, Z / Liu, H B / Yang, Y J / Gao, R L / Xu, B / Yuan, J Q

    Zhonghua xin xue guan bing za zhi

    2023  Volume 51, Issue 2, Page(s) 143–150

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Male ; Humans ; Middle Aged ; Aged ; Female ; Coronary Artery Disease/surgery ; Stroke Volume ; Percutaneous Coronary Intervention ; Prospective Studies ; Treatment Outcome ; Ventricular Function, Left ; Prognosis ; Risk Factors ; Myocardial Infarction/etiology ; Diabetes Mellitus
    Language Chinese
    Publishing date 2023-02-15
    Publishing country China
    Document type Observational Study ; English Abstract ; Journal Article
    ZDB-ID 603425-1
    ISSN 0253-3758
    ISSN 0253-3758
    DOI 10.3760/cma.j.cn112148-20220601-00432
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2276: Show issues Location:
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  8. Article: [Progress of surgical treatment for T1a glottic carcinoma].

    Huang, G J / Luo, M S / Zhang, J X / Liu, H B

    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery

    2018  Volume 31, Issue 9, Page(s) 725–728

    Abstract: T1a glottic laryngeal carcinoma is early laryngeal cancer,involving unilateral vocal cord. T he main surgical treatments are transoral laser surgery,open surgery,transoral robotic surgery and radiofrequency ablation technique. In this paper,progress of ... ...

    Abstract T1a glottic laryngeal carcinoma is early laryngeal cancer,involving unilateral vocal cord. T he main surgical treatments are transoral laser surgery,open surgery,transoral robotic surgery and radiofrequency ablation technique. In this paper,progress of surgical treatment for T1a glottic carcinoma were reviewed.
    MeSH term(s) Glottis/pathology ; Glottis/surgery ; Humans ; Laryngeal Neoplasms/surgery ; Laser Therapy ; Neoplasm Staging ; Retrospective Studies ; Treatment Outcome ; Vocal Cords
    Language Chinese
    Publishing date 2018-05-23
    Publishing country China
    Document type Journal Article ; Review
    ISSN 1001-1781
    ISSN 1001-1781
    DOI 10.13201/j.issn.1001-1781.2017.09.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [To explore the role of CT scan in the diagnosis of eosinophilic chronic rhinosinusitis].

    Zhu, C M / Liu, H B / Wu, W X / Xu, C

    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery

    2018  Volume 32, Issue 12, Page(s) 944–948

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Chronic Disease ; Humans ; Osteitis/diagnostic imaging ; Paranasal Sinuses ; Rhinitis/diagnostic imaging ; Sinusitis/diagnostic imaging ; Tomography, X-Ray Computed
    Language Chinese
    Publishing date 2018-06-19
    Publishing country China
    Document type Journal Article
    ISSN 1001-1781
    ISSN 1001-1781
    DOI 10.13201/j.issn.1001-1781.2018.12.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Single nucleotide polymorphisms rs102313, rs118231 and rs201832 of CTEP TaqIB gene correlated with lipid metabolism abnormalities and cerebral infarction in patients with atherosclerosis.

    Zhao, Z-H / Wang, Y-R / Li, R / Xiao, L / Xie, Y / Xie, N-C / Liu, H-B

    European review for medical and pharmacological sciences

    2021  Volume 25, Issue 23, Page(s) 7402–7408

    Abstract: Objective: The purpose of this study was to investigate the correlations of cholesterol ester transfer protein (CTEP) TaqIB gene polymorphism with lipid metabolism abnormalities and cerebral infarction (CI) in patients with atherosclerosis (AS).: ... ...

    Abstract Objective: The purpose of this study was to investigate the correlations of cholesterol ester transfer protein (CTEP) TaqIB gene polymorphism with lipid metabolism abnormalities and cerebral infarction (CI) in patients with atherosclerosis (AS).
    Patients and methods: A case-control study was conducted on 100 AS patients complicated with (CI) as AS+CI group, and 200 AS patients with matched age, gender and race as controls (AS group). Single nucleotide polymorphisms (SNPs) rs102313, rs118231 and rs201832 in the promoter region of CTEP TaqIB gene were classified by conformational differential gel electrophoresis. Then, Chi-square test was carried out to determine whether the distribution frequency of CTEP TaqIB genotypes conforms to the law of genetic equilibrium. In the meantime, the correlations of gene polymorphisms and allelotypes in the promoter region of CTEP TaqIB with CI and lipid metabolism abnormalities in AS patients were analyzed.
    Results: Hardy-Weinberg genetic equilibrium analysis showed that the three polymorphisms of CTEP TaqIB gene were in accordance with the genetic equilibrium distribution (p>0.05). Moreover, the results of gene association analysis revealed that the polymorphisms rs102313 and rs118231 and allelotypes in the promoter region of CTEP TaqIB gene were correlated with CI in AS patients (p<0.05). Specifically, AS patients with GG genotype and allele G at rs102313 and those with TT genotype and allele T at rs118231 had a higher risk of CI (p<0.05). Besides, the polymorphism rs102313 in the promoter region of CTEP TaqIB gene was markedly related to lipid metabolism abnormalities in AS patients (p<0.05).
    Conclusions: The polymorphisms rs102313 and rs118231 in the promoter region of CTEP TaqIB gene are associated with CI in AS patients, and the polymorphism rs102313 is remarkably correlated with lipid metabolism abnormalities in AS patients.
    MeSH term(s) Alleles ; Atherosclerosis/genetics ; Case-Control Studies ; Cerebral Infarction/genetics ; Cholesterol Ester Transfer Proteins/genetics ; Female ; Gene Frequency ; Genotype ; Humans ; Lipid Metabolism/genetics ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Promoter Regions, Genetic
    Chemical Substances Cholesterol Ester Transfer Proteins
    Language English
    Publishing date 2021-12-17
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202112_27437
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1887: Show issues Location:
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