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  1. Article: Open Up Your Bag.

    Liu, Helen

    Clinical diabetes : a publication of the American Diabetes Association

    2019  Volume 37, Issue 2, Page(s) 191–192

    Language English
    Publishing date 2019-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1025953-3
    ISSN 0891-8929
    ISSN 0891-8929
    DOI 10.2337/cd19-0096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2591: Show issues Location:
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  2. Article ; Online: Examining Violaceous Skin Discoloration during the COVID-19 Pandemic: Conducting Research in Resource Scarcity.

    Savage, Elizabeth / Lieder, Jessica / Liu, Helen / Lebovits, Sarah

    Advances in skin & wound care

    2023  Volume 36, Issue 3, Page(s) 137–141

    Abstract: Objective: To describe the observed patterns and presentations of violaceous discoloration that appeared to be related to the COVID-19 disease process.: Methods: This retrospective observational cohort study included adults who were COVID-19 positive ...

    Abstract Objective: To describe the observed patterns and presentations of violaceous discoloration that appeared to be related to the COVID-19 disease process.
    Methods: This retrospective observational cohort study included adults who were COVID-19 positive with purpuric/violaceous lesions in pressure-adjacent areas of the gluteus without preexisting pressure injury. Patients were admitted to an ICU at a single quaternary academic medical center between April 1 and May 15, 2020. Data were compiled by review of the electronic health record. The wounds were described by location, tissue type (violaceous, granulation, slough, eschar), wound margin (irregular, diffuse, nonlocalized), and periwound condition (intact).
    Results: A total of 26 patients were included in the study. Purpuric/violaceous wounds were found predominantly on White (92.3%) men (88.0%) aged 60 to 89 years (76.9%) with a body mass index 30 kg/m2 or higher (46.1%). The majority of wounds were located on the sacrococcygeal (42.3%) and fleshy gluteal regions (46.1%).
    Conclusions: Wounds were heterogeneous in appearance (poorly defined violaceous skin discoloration of acute onset), and the patient population had clinical characteristics similar to acute skin failure (eg, concomitant organ failures and hemodynamic instability). Additional larger population-based studies with biopsies may assist in finding patterns related to these dermatologic changes.
    MeSH term(s) Adult ; Male ; Humans ; Female ; COVID-19 ; Retrospective Studies ; Pandemics ; Skin ; Pressure Ulcer
    Language English
    Publishing date 2023-02-17
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 2012792-3
    ISSN 1538-8654 ; 1527-7941
    ISSN (online) 1538-8654
    ISSN 1527-7941
    DOI 10.1097/01.ASW.0000911988.75204.44
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Botulinum Toxin Injections for Psychiatric Disorders: A Systematic Review of the Clinical Trial Landscape.

    Demchenko, Ilya / Swiderski, Alyssa / Liu, Helen / Jung, Hyejung / Lou, Wendy / Bhat, Venkat

    Toxins

    2024  Volume 16, Issue 4

    Abstract: Botulinum toxin type A (BONT-A) has shown promise in improving the mood-related symptoms of psychiatric disorders by targeting muscles linked to the expression of negative emotions. We conducted a systematic review of past and ongoing efficacy trials of ... ...

    Abstract Botulinum toxin type A (BONT-A) has shown promise in improving the mood-related symptoms of psychiatric disorders by targeting muscles linked to the expression of negative emotions. We conducted a systematic review of past and ongoing efficacy trials of BONT-A therapy for psychiatric disorders to identify relevant trends in the field and discuss the refinement of therapeutic techniques. A comprehensive search for published clinical trials using BONT-A injections for psychiatric disorders was performed on 4 May 2023 through OVID databases (MEDLINE, Embase, APA PsycINFO). Unpublished clinical trials were searched through the ClinicalTrials.gov and International Clinical Trial Registry Platform public registries. The risk of bias was assessed using the JBI Critical Appraisal tools for use in systematic reviews. We identified 21 studies (17 published, 4 unpublished clinical trials) involving 471 patients. The studies focused on evaluating the efficacy of BONT-A for major depressive, borderline personality, social anxiety, and bipolar disorders. BONT-A was most commonly injected into the glabellar area, with an average dose ranging between 37.75 U and 44.5 U in published studies and between 32.7 U and 41.3 U in unpublished trials. The results indicated significant symptom reductions across all the studied psychiatric conditions, with mild adverse effects. Thus, BONT-A appears to be safe and well-tolerated for psychiatric disorders of negative affectivity. However, despite the clinical focus, there was a noted shortage of biomarker-related assessments. Future studies should focus on pursuing mechanistic explorations of BONT-A effects at the neurobiological level.
    MeSH term(s) Humans ; Mental Disorders/drug therapy ; Botulinum Toxins, Type A/therapeutic use ; Botulinum Toxins, Type A/administration & dosage ; Clinical Trials as Topic ; Treatment Outcome
    Chemical Substances Botulinum Toxins, Type A (EC 3.4.24.69)
    Language English
    Publishing date 2024-04-15
    Publishing country Switzerland
    Document type Journal Article ; Systematic Review ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins16040191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: What sticks after statistical learning: The persistence of implicit versus explicit memory traces.

    Liu, Helen / Forest, Tess Allegra / Duncan, Katherine / Finn, Amy S

    Cognition

    2023  Volume 236, Page(s) 105439

    Abstract: Statistical learning is a powerful mechanism that extracts even subtle regularities from our information-dense worlds. Recent theories argue that statistical learning can occur through multiple mechanisms-both the conventionally assumed automatic process ...

    Abstract Statistical learning is a powerful mechanism that extracts even subtle regularities from our information-dense worlds. Recent theories argue that statistical learning can occur through multiple mechanisms-both the conventionally assumed automatic process that precipitates unconscious learning, and an attention-dependent process that brings regularities into conscious awareness. While this view has gained popularity, there are few empirical dissociations of the hypothesized implicit and explicit forms of statistical learning. Here we provide strong evidence for this dissociation in two ways. First, we show in healthy adults (N = 60) that implicit and explicit traces have divergent consolidation trajectories, with implicit knowledge of structure strengthened over a 24-h period, while precise explicit representations tend to decay. Second, we demonstrate that repeated testing strengthens the retention of explicit representations but that implicit statistical learning is uninfluenced by testing. Together these dissociations provide much needed support for the reconceptualization of statistical learning as a multi-component construct.
    MeSH term(s) Adult ; Humans ; Memory ; Learning ; Attention ; Consciousness
    Language English
    Publishing date 2023-03-17
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1499940-7
    ISSN 1873-7838 ; 0010-0277
    ISSN (online) 1873-7838
    ISSN 0010-0277
    DOI 10.1016/j.cognition.2023.105439
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Scalable optical manufacture of dynamic structural colour in stretchable materials.

    Miller, Benjamin Harvey / Liu, Helen / Kolle, Mathias

    Nature materials

    2022  Volume 21, Issue 9, Page(s) 1014–1018

    Abstract: Structurally coloured materials that change their colour in response to mechanical stimuli are uniquely suited for optical sensing and visual ... ...

    Abstract Structurally coloured materials that change their colour in response to mechanical stimuli are uniquely suited for optical sensing and visual communication
    MeSH term(s) Color ; Elastomers/chemistry ; Humans ; Robotics
    Chemical Substances Elastomers
    Language English
    Publishing date 2022-08-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2088679-2
    ISSN 1476-4660 ; 1476-1122
    ISSN (online) 1476-4660
    ISSN 1476-1122
    DOI 10.1038/s41563-022-01318-x
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  6. Article ; Online: Acute Aortic Occlusion and Its Sequelae: Metabolic, Pathologic Etiology, and Management.

    Hines, George L / Liu, Helen H

    Cardiology in review

    2020  Volume 29, Issue 2, Page(s) 57–61

    Abstract: Acute occlusion of the abdominal aorta is a catastrophic occurrence that results in high risk of limb loss and death. The etiology has historically been either acute embolism obstructing the aortic bifurcation in 8% to 75% of patients, or thrombosis of ... ...

    Abstract Acute occlusion of the abdominal aorta is a catastrophic occurrence that results in high risk of limb loss and death. The etiology has historically been either acute embolism obstructing the aortic bifurcation in 8% to 75% of patients, or thrombosis of existing aorta-iliac occlusive disease in 35% to 84% of patients. Other etiologies include thrombosis of either a previously placed endograft or aortic graft or acute dissection. The most common symptoms are severe pain in almost 100% of patients or lower extremity paralysis/paresis in up to 80% of patients. Evaluation in the past was by angiography, but presently, computed tomography angiography is the preferred imaging study. Treatment is dependent on the etiology and includes embolectomy, aorta femoral bypass, axillary femoral bypass, and endovascular techniques. The aim of intervention is to restore flow in the shortest time period. Mortality rates vary widely from 17% to 52%, amputation occurs in up to 30% of patients. Paraplegia can occur in 40% of patients, renal insufficiency in 40% to 70%, and visceral ischemia in 6% to 14%. Both mortality and morbidity are affected by the duration of ischemia and the local and systemic complications of reperfusion injury. Complications of acute aortic occlusion can be reduced by a more prompt diagnosis, rapid intervention, and a more rapid and complete reestablishment of perfusion.
    MeSH term(s) Aorta, Abdominal/surgery ; Aortic Diseases/diagnosis ; Aortic Diseases/etiology ; Aortic Diseases/therapy ; Arterial Occlusive Diseases/etiology ; Arterial Occlusive Diseases/surgery ; Blood Vessel Prosthesis Implantation ; Humans ; Ischemia/etiology ; Ischemia/surgery ; Thrombosis ; Treatment Outcome
    Language English
    Publishing date 2020-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1294965-6
    ISSN 1538-4683 ; 1061-5377
    ISSN (online) 1538-4683
    ISSN 1061-5377
    DOI 10.1097/CRD.0000000000000313
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4491: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Book: Thriving China

    Liu, Helen

    collection of contemporary Chinese architecture

    2013  

    Author's details Ed.: Helen Liu
    Keywords Architecture/History
    Language English
    Size 355 S., zahlr. Ill., graph. Darst.
    Publisher Design Media Publishing
    Publishing place Hong Kong
    Document type Book
    ISBN 9789881566461 ; 9881566460
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  8. Book: Museum design proposals

    Liu, Helen

    2013  

    Author's details Editing Helen Liu
    Language English
    Size 269 S., Ill., graph. Darst., 29 cm
    Publisher Design Media Publ. Ltd
    Publishing place Hong Kong
    Document type Book
    Note Includes index
    ISBN 9789881506993 ; 9881506999
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  9. Article ; Online: Is There an Association between Platelet Count and Blood Loss in the Parturient? A Retrospective Study.

    Beilin, Yaakov / Liu, Helen / Hyers, Benjamin M / Mijovic, Vasilije / Katz, Daniel

    American journal of perinatology

    2023  

    Abstract: Objective:  The influence of thrombocytopenia on blood loss and postpartum hemorrhage (PPH) has been conflicting. Our aim was to determine if there is an association between predelivery platelet count and quantitative blood loss (QBL) and PPH in both ... ...

    Abstract Objective:  The influence of thrombocytopenia on blood loss and postpartum hemorrhage (PPH) has been conflicting. Our aim was to determine if there is an association between predelivery platelet count and quantitative blood loss (QBL) and PPH in both vaginal (VD) and cesarean deliveries (CD).
    Study design:  We conducted a retrospective database study at a single institution from April 1, 2017 to September 9, 2020. The platelet count closest to time of delivery and the QBL was assessed separately for VD and CD.
    Results:  A total of 22,479 records were reviewed, of which 16,822 (75%) were VD and 5,657 (25%) were CD. A total of 2,600 (12%) patients had thrombocytopenia, defined as a platelet count <150,000/mm
    Conclusion:  We found a statistically significant association between lower predelivery platelet counts and QBL and PPH. The clinical significance of these results is debatable, because at all platelet count ranges, differences in blood loss were small.
    Key points: · Hemorrhage is etiology of morbidity and mortality in obstetric parturients.. · We found a small increase in blood loss in those with thrombocytopenia.. · The clinical relevance of these findings is debatable since the increased blood loss was small..
    Language English
    Publishing date 2023-12-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/s-0043-1778009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1929: Show issues Location:
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  10. Article ; Online: Racial Disparities in Documented Chief Complaints and Diagnoses in Sepsis Patients.

    Liu, Helen / McCroskery, Stephen / Rajasekaran, Vignesh / Linker, Anne S / Poeran, Jashvant / Truong, Tuyet-Trinh

    Journal of intensive care medicine

    2023  Volume 38, Issue 7, Page(s) 630–634

    Abstract: Background: Using History and Physical Examination (H&P) notes, we investigated potential racial differences in documented chief complaints and problems among sepsis patients admitted to the intensive care unit.: Methods: Patient records from Medical ...

    Abstract Background: Using History and Physical Examination (H&P) notes, we investigated potential racial differences in documented chief complaints and problems among sepsis patients admitted to the intensive care unit.
    Methods: Patient records from Medical Information Mart for Intensive Care (MIMIC-III) dataset indicating a diagnosis of sepsis were included. First recorded clinical notes for each hospital admission were assessed; free text information was specifically extracted on (1) chief complaints, and (2) problems recorded in the Assessment & Plan (A&P) section. The top 10 for each were compared between Black and White patients.
    Results: In initial H&P notes of 17 434 sepsis patients (n = 1229 Black and n = 9806 White), the top 10 most common chief complaints were somewhat similar between Black and White patients. However, relative differences existed in terms of ranking, specifically for altered mental status which was more commonly reported in Black versus White patients (11.7% vs 7.8%
    Conclusions: This analysis supports the hypothesis that there may be racial differences in early sepsis presentation and possible provider interpretation of these complaints.
    MeSH term(s) Humans ; Hospitalization ; Racial Groups ; Retrospective Studies ; Sepsis/diagnosis ; Healthcare Disparities ; White ; Black or African American
    Language English
    Publishing date 2023-02-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632828-3
    ISSN 1525-1489 ; 0885-0666
    ISSN (online) 1525-1489
    ISSN 0885-0666
    DOI 10.1177/08850666231155397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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