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Article ; Online: Nutritional and Physiological Effects of Postharvest UV Radiation on Vegetables: A Review.

Sonntag, Frederike / Liu, Huihui / Neugart, Susanne

Journal of agricultural and food chemistry

2023 Volume 71, Issue 26, Page(s) 9951–9972

Abstract: Effective ultraviolet (UV) irradiation has been used as a postharvest technology to reduce decay, delay ripening, and delay senescence in crop products. In this review, the effects of UV radiation of different wavelengths and doses on physiological and ... ...

Abstract	Effective ultraviolet (UV) irradiation has been used as a postharvest technology to reduce decay, delay ripening, and delay senescence in crop products. In this review, the effects of UV radiation of different wavelengths and doses on physiological and phytochemical parameters in postharvest vegetables are discussed in summary, including appearance (color and texture), microbial load, respiration rate, enzymatic antioxidant system, and various bioactive compounds (phenolic compounds, carotenoids, chlorophylls, vitamins, glucosinolates, betalains, and antioxidant activities). In particular, postharvest UV radiation affects oxidative metabolism and increases the antioxidant activity of plant products, which could help delay yellowing and senescence of vegetables, trigger defense responses, and reduce decay and diseases. In some cases, irradiation stimulates the synthesis of bioactive secondary metabolites that may improve the nutritional value of vegetables. The findings presented in this review are very useful and valuable for the preservation and improvement of the nutritional quality of vegetables after harvest. It will also provide scientific support for industrial and commercial applications of UV radiation in postharvest.
MeSH term(s)	Vegetables/metabolism ; Antioxidants/metabolism ; Ultraviolet Rays ; Phenols/metabolism ; Nutritive Value ; Fruit/chemistry
Chemical Substances	Antioxidants ; Phenols
Language	English
Publishing date	2023-06-21
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	241619-0
ISSN	1520-5118 ; 0021-8561
ISSN (online)	1520-5118
ISSN	0021-8561
DOI	10.1021/acs.jafc.3c00481
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Article ; Online: Does the dual circulation coupling synergy facilitate firm survival?--Evidence from China.

Ran, Lijun / Li, Xin / Wang, Kang / Liu, Huihui

PloS one

2023 Volume 18, Issue 8, Page(s) e0290448

Abstract: The "dual circulation" development pattern is a major economic strategy proposed by China. Using samples gathered from firms located in the Haidian Science and Technology Park in Zhongguancun between 2013 and 2019, this paper constructs an index system ... ...

Abstract	The "dual circulation" development pattern is a major economic strategy proposed by China. Using samples gathered from firms located in the Haidian Science and Technology Park in Zhongguancun between 2013 and 2019, this paper constructs an index system for measuring the degree of synergy of the dual circulation coupling of the firms, and then uses the Cloglog survival model to empirically verify its effect on the survival of firms. It is found that the dual circulation coupling synergy of firms significantly contributes to firm survival, a finding that still holds after robustness tests. Mechanism tests show that firm dual circulation coupling synergies contribute to firm survival by promoting firm innovation, market demand, and resource allocation efficiency. Further analysis reveals that the coupled synergy of the dual circulation of firms contributes more significantly to the survival of growing and mature firms, MSMEs, private firms and non-start-up firms. This paper is the first to measure dual circulation. It provides micro-theoretical mechanisms and relevant empirical evidence for the dual circulation coupling synergy for firm survival.
MeSH term(s)	China ; Resource Allocation ; Technology
Language	English
Publishing date	2023-08-21
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0290448
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Article: The Effects of Emotion, Spokesperson Type, and Benefit Appeals on Persuasion in Health Advertisements: Evidence from Macao.

Jiang, Ling / Liu, Huihui / Jiang, Nan

Behavioral sciences (Basel, Switzerland)

2023 Volume 13, Issue 11

Abstract: Enhancing public awareness for epidemic prevention is crucial for safeguarding public health. This experimental study investigated the effectiveness of a combined approach involving three persuasive elements in public health advertising. Specifically, ... ...

Abstract	Enhancing public awareness for epidemic prevention is crucial for safeguarding public health. This experimental study investigated the effectiveness of a combined approach involving three persuasive elements in public health advertising. Specifically, the study examined the interplay between emotional appeals (fear messages versus efficacy messages) and spokesperson type on the public's response to health announcements. The results demonstrated that fear messages were more persuasive when conveyed by real human spokespersons (versus animated spokespersons), whereas efficacy messages were more acceptable when conveyed by animated spokespersons (versus real humans). Furthermore, the study revealed that the impact of emotional appeals and spokesperson type is moderated by benefit appeals (self-benefit or other-benefit). The joint effects of these persuasive variables on individuals' intention to adopt preventive measures indicated that the interactions significantly differed across the two types of benefit appeal. Taken together, the findings represent a pioneering contribution to the field of health communication by comparing the persuasive effects of different combinations of emotional appeals, spokesperson types, and benefit appeals on public behavior. These findings offer practical guidance for public communicators to design more appropriate health advertisements based on the results of this study, thereby enhancing public acceptance of disease prevention measures.
Language	English
Publishing date	2023-11-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2651997-5
ISSN	2076-328X
ISSN	2076-328X
DOI	10.3390/bs13110917
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Article ; Online: A study of

Cheng, Guojie / Wang, Panpan / Liu, Huihui / Zhang, Dawei

Physical chemistry chemical physics : PCCP

2023 Volume 25, Issue 35, Page(s) 23658–23666

Abstract: More and more studies have confirmed the importance of polarization effects in hydrogen bonding interactions in protein folding simulations. In this paper, a recently developed charge update scheme termed polarized structure-specific backbone charge ( ... ...

Abstract	More and more studies have confirmed the importance of polarization effects in hydrogen bonding interactions in protein folding simulations. In this paper, a recently developed charge update scheme termed polarized structure-specific backbone charge (PSBC) model was applied to the folding of 10-residue chignolin. A comparison between simulations performed using PSBC and a nonpolarizable (AMBER99SB) force field demonstrably showed the importance of the electrostatic polarization effect in the folding of the short β-hairpin peptide by a series of analyses such as DSSP, free-energy landscape, hydrogen bond occupancy, and melting curve. The PSBC model was further validated by folding two other chignolin variants.
MeSH term(s)	Molecular Dynamics Simulation ; Hydrogen Bonding ; Protein Folding ; Static Electricity
Chemical Substances	chignolin
Language	English
Publishing date	2023-09-13
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/d3cp03070a
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Article ; Online: Comprehensive mapping of B lymphocyte immune dysfunction in idiopathic nephrotic syndrome children.

Ye, Qing / Liu, Huihui / Wang, Dongjie / Mao, Jianhua

Clinical and translational medicine

2023 Volume 13, Issue 2, Page(s) e1177

MeSH term(s)	Humans ; Child ; Nephrotic Syndrome ; B-Lymphocytes
Language	English
Publishing date	2023-02-03
Publishing country	United States
Document type	Letter ; Research Support, Non-U.S. Gov't
ZDB-ID	2697013-2
ISSN	2001-1326 ; 2001-1326
ISSN (online)	2001-1326
ISSN	2001-1326
DOI	10.1002/ctm2.1177
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Article ; Online: Impact of non-pharmaceutical interventions during the COVID-19 pandemic on common childhood respiratory viruses - An epidemiological study based on hospital data.

Ye, Qing / Liu, Huihui

Microbes and infection

2021 Volume 24, Issue 1, Page(s) 104911

Abstract: Considering common childhood respiratory viruses and SARS-CoV-2 share similar transmission routes, non-pharmaceutical interventions (NPIs) to prevent SARS-CoV-2 may affect the epidemiology of respiratory viruses. Therefore, our study aimed to observe the ...

Abstract	Considering common childhood respiratory viruses and SARS-CoV-2 share similar transmission routes, non-pharmaceutical interventions (NPIs) to prevent SARS-CoV-2 may affect the epidemiology of respiratory viruses. Therefore, our study aimed to observe the epidemiologic characteristics of common childhood respiratory viruses in 2020 (after the pandemic) compared with 2019 (before the pandemic) in Hangzhou, China. The data were compared between 2019 and 2020 based on age and month, respectively. One or more viruses were detected in 3135/21452 (14.61%) specimens in 2019, which was significantly lower in 1110/8202 (13.53%) specimens in 2020. Respiratory syncytial virus (RSV) was the most commonly detected virus in 2019 and 2020. The positive rate of adenovirus (ADV), parainfluenza virus (PIV)1, PIV2, and PIV3 in 2020 was significantly decreased in 2019. In 2020, RSV replaced ADV as the most predominant virus in children aged 1-6 years, and the positive rate of influenza virus A (FluA), influenza virus B (FluB), PIV1, and PIV2 was not correlated to age. FluA, FluB, and PIV2 were not almost detected from February 2020. The positive rates of ADV and PIV1 were uncorrelated to the month in 2020. By strict NPIs, besides controlling the COVID-19 pandemic, incredible progress has been made to reduce the prevalence of common childhood respiratory viruses.
MeSH term(s)	COVID-19 ; Child ; Epidemiologic Studies ; Hospitals ; Humans ; Infant ; Influenza B virus ; Pandemics/prevention & control ; Respiratory Tract Infections/epidemiology ; Respiratory Tract Infections/prevention & control ; SARS-CoV-2
Language	English
Publishing date	2021-12-03
Publishing country	France
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1465093-9
ISSN	1769-714X ; 1286-4579
ISSN (online)	1769-714X
ISSN	1286-4579
DOI	10.1016/j.micinf.2021.104911
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Article ; Online: Rapid analysis and authentication of Chinese propolis using nanoelectrospray ionization mass spectrometry combined with machine learning.

Wang, Ruiyue / Qu, Liangliang / Wang, Yiran / Qu, Yijiao / Xie, Quanyuan / Liu, Huihui / Nie, Zongxiu

Food chemistry

2024 Volume 447, Page(s) 138928

Abstract: In this study, we established a simple, rapid, and high-throughput method for the analysis and classification of propolis samples. We utilized nanoESI-MS to analyze 37 samples of propolis from China for the first time, obtaining characteristic ... ...

Abstract	In this study, we established a simple, rapid, and high-throughput method for the analysis and classification of propolis samples. We utilized nanoESI-MS to analyze 37 samples of propolis from China for the first time, obtaining characteristic fingerprint spectra in negative ion mode, which were then integrated with multivariate analysis to explore variations between water extract of propolis (WEP) and ethanol extract of propolis (EEP). Furthermore, we categorized propolis samples based on different climate zones and colors, screening 10 differential metabolites among propolis from various climate zones, and 11 differential metabolites among propolis samples of different color. By employing machine learning models, we achieved high-precision discrimination and prediction between samples from different climate zones and colors, achieving predictive accuracies of 95.6% and 85.6%, respectively. These results highlight the significant potential of the nanoESI-MS coupled with machine learning methodology for precise classification within the realm of food products.
MeSH term(s)	Propolis/chemistry ; Mass Spectrometry ; Ascomycota ; Climate ; Machine Learning ; Spectrometry, Mass, Electrospray Ionization/methods
Chemical Substances	Propolis (9009-62-5)
Language	English
Publishing date	2024-03-04
Publishing country	England
Document type	Journal Article
ZDB-ID	243123-3
ISSN	1873-7072 ; 0308-8146
ISSN (online)	1873-7072
ISSN	0308-8146
DOI	10.1016/j.foodchem.2024.138928
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Article ; Online: Inhibitory effects and mechanisms of phenolic compounds in rapeseed oil on advanced glycation end product formation in chemical and cellular models in vitro.

Liu, Huihui / Zhang, Ruiying / Wang, Wen / Xia, Xiaoyang / Xu, Zhenxia / Xiang, Xia

Food chemistry

2024 Volume 447, Page(s) 139056

Abstract: Sinapic acid (SA), canolol (CAO) and canolol dimer (CAO dimer) are the main phenolic compounds in rapeseed oil. However, their possible efficacy against glycation remains unclear. This study aims to explore the impacts of these substances on the ... ...

Abstract	Sinapic acid (SA), canolol (CAO) and canolol dimer (CAO dimer) are the main phenolic compounds in rapeseed oil. However, their possible efficacy against glycation remains unclear. This study aims to explore the impacts of these substances on the formation of advanced glycation end products (AGEs) based on chemical and cellular models in vitro. Based on fluorescence spectroscopy results, three chemical models of BSA-fructose, BSA-methylglyoxal (MGO), and arginine (Arg)-MGO showed that SA/CAO/CAO dimer could effectively reduce AGE formation but with different abilities. After SA/CAO/CAO dimer incubation, effective protection against BSA protein glycation was observed and three different MGO adducts were formed. In MGO-induced HUVEC cell models, only CAO and CAO dimer significantly inhibited oxidative stress and cell apoptosis, accompanied by the regulation of the Nrf2-HO-1 pathway. During the inhibition, 20 and 12 lipid mediators were reversed in the CAO and CAO dimer groups compared to the MGO group.
MeSH term(s)	Glycation End Products, Advanced/chemistry ; Rapeseed Oil ; Magnesium Oxide ; Phenols/chemistry ; Pyruvaldehyde/chemistry ; Vinyl Compounds
Chemical Substances	4-vinyl-2,6-dimethoxyphenol (ZB5OK5EX8B) ; Glycation End Products, Advanced ; Rapeseed Oil ; Magnesium Oxide (3A3U0GI71G) ; Phenols ; Pyruvaldehyde (722KLD7415) ; Vinyl Compounds
Language	English
Publishing date	2024-03-19
Publishing country	England
Document type	Journal Article
ZDB-ID	243123-3
ISSN	1873-7072 ; 0308-8146
ISSN (online)	1873-7072
ISSN	0308-8146
DOI	10.1016/j.foodchem.2024.139056
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Article ; Online: Comprehensive mapping of saliva by multiomics in children with idiopathic nephrotic syndrome.

Ye, Qing / Liu, Huihui / Meng, Hanyan / Wang, Dongjie / Zhang, Jiayu / Zhu, Shifan / Mao, Jianhua

Nephrology (Carlton, Vic.)

2024

Abstract: Aim: Saliva can reflect an individual's physiological status or susceptibility to systemic disease. However, little attention has been given to salivary analysis in children with idiopathic nephrotic syndrome (INS). We aimed to perform a comprehensive ... ...

Abstract	Aim: Saliva can reflect an individual's physiological status or susceptibility to systemic disease. However, little attention has been given to salivary analysis in children with idiopathic nephrotic syndrome (INS). We aimed to perform a comprehensive analysis of saliva from INS children. Methods: A total of 18 children (9 children with INS and 9 normal controls) were recruited. Saliva was collected from each INS patient in the acute and remission phases. 16S rRNA gene sequencing, widely targeted metabolomics, and 4D-DIA proteomics were performed. Results: Actinobacteria and Firmicutes were significantly enriched in the pretreatment group compared with the normal control group, while Bacteroidota and Proteobacteria were significantly decreased. A total of 146 metabolites were identified as significantly different between INS children before treatment and normal controls, which covers 17 of 23 categories. KEGG enrichment analysis revealed three significantly enriched pathways, including ascorbate and aldarate metabolism, pentose and glucuronate interconversions, and terpenoid backbone biosynthesis (P < 0.05). A total of 389 differentially expressed proteins were selected between INS children before treatment and normal controls. According to the KEGG and GO enrichment analyses of the KOGs, abnormal ribosome structure and function and humoral immune disorders were the most prominent differences between INS patients and normal controls in the proteomic analysis. Conclusion: Oral microbiota dysbiosis may modulate the metabolic profile of saliva in children with INS. It is hypothesized that children with INS might have "abnormal ribosome structure and function" and "humoral immune disorders".
Language	English
Publishing date	2024-04-18
Publishing country	Australia
Document type	Journal Article
ZDB-ID	1303661-0
ISSN	1440-1797 ; 1320-5358
ISSN (online)	1440-1797
ISSN	1320-5358
DOI	10.1111/nep.14308
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Article ; Online: Potential Disrupting Effects of Wastewater-Derived Disinfection Byproducts on Chinese Rare Minnow (

Zhao, Songshan / Yang, Xianhai / Liu, Huihui / Xi, Yue / Li, Jing

Environmental science & technology

2023 Volume 57, Issue 8, Page(s) 3228–3237

Abstract: The available information about whether wastewater-derived disinfection byproducts (DBPs) could elicit potential endocrine-related detrimental effects on aquatic organisms was scarce. Herein, the potential disrupting effects and underlying binding ... ...

Abstract	The available information about whether wastewater-derived disinfection byproducts (DBPs) could elicit potential endocrine-related detrimental effects on aquatic organisms was scarce. Herein, the potential disrupting effects and underlying binding mechanism of 14 wastewater-derived aliphatic and aromatic DBPs and 12 other substances on Chinese rare minnow (
MeSH term(s)	Animals ; Cyprinidae ; Disinfection ; Prealbumin/metabolism ; Wastewater ; Disinfectants/toxicity ; Water Purification
Chemical Substances	Prealbumin ; Wastewater ; Disinfectants
Language	English
Publishing date	2023-02-13
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1520-5851
ISSN (online)	1520-5851
DOI	10.1021/acs.est.2c06192
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