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  1. Article ; Online: Optomechanical squeezing with pulse modulation.

    Xiong, Biao / Chao, Shilei / Shan, Chuanjia / Liu, Jibing

    Optics letters

    2023  Volume 47, Issue 21, Page(s) 5545–5548

    Abstract: Quantum control technology provides an increasingly useful toolbox for quantum information tasks. In this Letter, by introducing a pulsed coupling to a standard optomechanical system, we show that stronger squeezing can be obtained with pulse modulation ... ...

    Abstract Quantum control technology provides an increasingly useful toolbox for quantum information tasks. In this Letter, by introducing a pulsed coupling to a standard optomechanical system, we show that stronger squeezing can be obtained with pulse modulation due to the reduction of the heating coefficient. Also, the general squeezed states, such as the squeezed vacuum, squeezed coherent, and squeezed cat states, can be obtained with their squeezing level exceeding 3 dB. Moreover, our scheme is robust to cavity decay, thermal temperature, and classical noise, which is friendly to experiments. The present work can extend the application of quantum engineering technology in optomechanical systems.
    Language English
    Publishing date 2023-05-23
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.471230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Nonreciprocal coupling modulated difference-sideband generation in a double-cavity optomechanical system.

    Yang, Lin / Mao, Mian / Kong, Cui / Liu, Jibing

    Optics express

    2023  Volume 31, Issue 21, Page(s) 34560–34576

    Abstract: We theoretically study the difference-sideband generation in a double-cavity optomechanical system with nonreciprocal coupling. Beyond the conventional linearized description of optomechanical interactions, we derive analytical expressions for the ... ...

    Abstract We theoretically study the difference-sideband generation in a double-cavity optomechanical system with nonreciprocal coupling. Beyond the conventional linearized description of optomechanical interactions, we derive analytical expressions for the efficiency of difference-sideband generation by using a perturbation method. Here we investigate bistable behaviors of the system and show the difference-sideband generation modulated by the nonreciprocal coupling strength between the two cavities. We find that the nonreciprocal coupling strength can not only affect the bistability of the system but also lead to different efficiencies of difference-sideband generation at low power. To achieve high efficiency of difference-sideband generation, we give the optimal matching conditions under different parameter mechanisms. Especially as the power increases, we find new matching conditions with remarkable difference-sideband generation emerging, which is attribute to the strong coherence between the cavity field and the mechanical oscillator. Furthermore, a feasible scheme to obtain difference-sideband generation by employing multiple adjustable variables is proposed. Our results may find applications in nonreciprocal optical frequency combs and communications, and provide a potential method for precision measurements and on-chip manipulation of light transmission.
    Language English
    Publishing date 2023-10-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.501336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Superconductivity in Bi-Doped BaFe

    Si, Jiabin / Zhao, Jianfa / Liu, Ying / Jin, Changqing / Liu, Jibing / Xing, Lingyi

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 4

    Abstract: We have successfully synthesized a series of Bi-doped ... ...

    Abstract We have successfully synthesized a series of Bi-doped BaFe
    Language English
    Publishing date 2024-02-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17040929
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  4. Article: Efficacy of TACE Combined with Lenvatinib Plus Sintilimab for Hepatocellular Carcinoma with Tumor Thrombus in the Inferior Vena Cava and/or Right Atrium.

    Ning, Shangkun / Li, Xinge / Ma, Xiangyu / Liu, Jibing / Chang, Xu

    Journal of hepatocellular carcinoma

    2023  Volume 10, Page(s) 1511–1525

    Abstract: Purpose: To validate the safety and effectiveness of transarterial chemoembolization (TACE) combination with lenvatinib and sintilimab in treating hepatocellular carcinoma (HCC) patients with inferior vena cava (IVC) and/or right atrium (RA) tumor ... ...

    Abstract Purpose: To validate the safety and effectiveness of transarterial chemoembolization (TACE) combination with lenvatinib and sintilimab in treating hepatocellular carcinoma (HCC) patients with inferior vena cava (IVC) and/or right atrium (RA) tumor thrombosis (TT).
    Methods: This study retrospectively analyzed HCC patients with IVC and/or RA TT treated with TACE combined with lenvatinib plus sintilimab. Overall survival (OS), progression-free survival (PFS), objective response rate (ORR), and disease control rate (DCR) were calculated to evaluate the anti-tumor efficacy. Treatment-related adverse events (TRAEs) were analyzed to assess the safety profiles.
    Results: A total of 58 patients were screened for eligibility between March 2019 and May 2022. At the time of data collection, 48.2% of patients were still receiving treatment. The median follow-up was 23.5 months. The ORR was 48.3%, the DCR was 91.4%, the median OS was 17.3 months, and the median PFS was 13.0 months. The ORR for IVC/RA TT was 62.1%, DCR was 94.9%, and the median PFS was 14.3 months. 56.9% of patients experienced ≥ grade 3 TRAEs, such as hypertension (10.3%) and elevated liver enzymes (13.8%). No new safety signals were identified. Participants with low levels of serum PCT value had satisfactory prognoses.
    Conclusion: TACE combination with lenvatinib plus sintilimab is effective in treating HCC with IVC and/or RA TT. The toxicities were manageable, with no unexpected safety signals. The baseline levels of serum PCT might be the predictive biomarkers for the triple combination therapy.
    Language English
    Publishing date 2023-09-13
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2780784-8
    ISSN 2253-5969
    ISSN 2253-5969
    DOI 10.2147/JHC.S410967
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Carbocistein improves airway remodeling in asthmatic mice.

    Zhou, Liang / Liu, Jibing / Wang, Li / He, Yunfei / Zhang, Jianyong

    American journal of translational research

    2022  Volume 14, Issue 8, Page(s) 5583–5590

    Abstract: Background: The alleviating effects of carbocisteine (S-carboxymethylcysteine, SCMC) have been implicated in chronic obstructive pulmonary disease; however, very little is known about its mechanisms in asthma. In this study, we aimed to investigate the ... ...

    Abstract Background: The alleviating effects of carbocisteine (S-carboxymethylcysteine, SCMC) have been implicated in chronic obstructive pulmonary disease; however, very little is known about its mechanisms in asthma. In this study, we aimed to investigate the effects of SCMC on airway remodeling in asthmatic mice induced by ovalbumin (OVA).
    Methods: The asthma mouse model was generated by OVA sensitization and stimulation and subsequently intervened by SCMC or dexamethasone. Bronchoalveolar lavage fluid (BALF) and lung tissues were collected from each group of mice. The TGF-β1 levels in BALF were measured by ELISA. Masson's staining was used to detect collagen fiber deposition in mouse airway tissues, while immunohistochemistry and RT-qPCR were conducted to examine the protein and mRNA expression of TGF-β1 in mouse lung airway tissues, respectively. The correlation between TGF-β1 mRNA expression and the area of collagen fiber deposition in airway tissues was analyzed by Pearson's correlation coefficient.
    Results: The area of collagen fiber deposition in the airway tissues of asthmatic mice was significantly increased, while SCMC alleviated the collagen fiber deposition in the airway tissues. TGF-β1 expression was significantly elevated in BALF and airway tissues of asthmatic mice, while SCMC inhibited TGF-β1 expression. TGF-β1 expression was significantly and positively correlated with collagen fiber deposition in mouse airway tissues.
    Conclusions: SCMC intervention improves collagen fiber deposition in airway tissues and inhibits TGF-β1 expression in asthmatic mice.
    Language English
    Publishing date 2022-08-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2471058-1
    ISSN 1943-8141
    ISSN 1943-8141
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  6. Article ; Online: Divergent Access to Polycyclic

    Xia, Jiajin / Liu, Jibing / Yu, Yinghua / Zhang, Jian / Huang, Xueliang

    Organic letters

    2022  Volume 24, Issue 23, Page(s) 4298–4303

    Abstract: Catalytic dearomatization has been considered as a valuable approach to convert readily accessible flat molecules to products with three-dimensional frameworks. Herein, an unprecedented gold-catalyzed oxidative Büchner-type cyclopropanation is described ... ...

    Abstract Catalytic dearomatization has been considered as a valuable approach to convert readily accessible flat molecules to products with three-dimensional frameworks. Herein, an unprecedented gold-catalyzed oxidative Büchner-type cyclopropanation is described that enables the cycloisomerization of diynamides. By variation of the position of substituents on the phenyl ring, a variety of fused
    Language English
    Publishing date 2022-06-06
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.2c01807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Divergent Access to Polycyclic N-Heterocyclic Compounds through Büchner-Type Dearomatization Enabled Cycloisomerization of Diynamides under Gold Catalysis

    Xia, Jiajin / Liu, Jibing / Yu, Yinghua / Zhang, Jian / Huang, Xueliang

    Organic letters. 2022 June 06, v. 24, no. 23

    2022  

    Abstract: Catalytic dearomatization has been considered as a valuable approach to convert readily accessible flat molecules to products with three-dimensional frameworks. Herein, an unprecedented gold-catalyzed oxidative Büchner-type cyclopropanation is described ... ...

    Abstract Catalytic dearomatization has been considered as a valuable approach to convert readily accessible flat molecules to products with three-dimensional frameworks. Herein, an unprecedented gold-catalyzed oxidative Büchner-type cyclopropanation is described that enables the cycloisomerization of diynamides. By variation of the position of substituents on the phenyl ring, a variety of fused N-heterocyclic products with challenging structural skeletons were obtained divergently.
    Keywords catalytic activity ; chemical reactions ; heterocyclic nitrogen compounds
    Language English
    Dates of publication 2022-0606
    Size p. 4298-4303.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1523-7052
    DOI 10.1021/acs.orglett.2c01807
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Gold-Catalyzed Oxidative Cascade Cyclization of 1,3-Diynamides: Polycyclic N-Heterocycle Synthesis via Construction of a Furopyridinyl Core.

    Liu, Jibing / Zhu, Lei / Wan, Wan / Huang, Xueliang

    Organic letters

    2020  Volume 22, Issue 8, Page(s) 3279–3285

    Abstract: A facile and practical approach to construct a furopyridinyl motif through a gold-catalyzed cascade cyclization of easily accessible diynamides is described. This strategy offers a straightforward approach to furo[2,3- ...

    Abstract A facile and practical approach to construct a furopyridinyl motif through a gold-catalyzed cascade cyclization of easily accessible diynamides is described. This strategy offers a straightforward approach to furo[2,3-
    Language English
    Publishing date 2020-04-03
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.0c01086
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  9. Article ; Online: Magnon-mediated nonreciprocal microwave transmission based on quantum interference.

    Kong, Cui / Bao, Xi-Min / Liu, Ji-Bing / Xiong, Hao

    Optics express

    2021  Volume 29, Issue 16, Page(s) 25477–25487

    Abstract: Nonreciprocity has always been a subject of interest and plays a key role in a variety of applications like signal processing and noise isolation. In this work, we propose a simple and feasible scheme to implement nonreciprocal microwave transmission in ... ...

    Abstract Nonreciprocity has always been a subject of interest and plays a key role in a variety of applications like signal processing and noise isolation. In this work, we propose a simple and feasible scheme to implement nonreciprocal microwave transmission in a high-quality-factor superconducting cavity with ferrimagnetic materials. We derive necessary requirements to create nonreciprocity in our system where a magnon mode and two microwave modes are coupled to each other, highlighting the adjustability of a static magnetic field controlled nonreciprocal transmission based on quantum interference between different transmission paths, which breaks time-reversal symmetry of the three-mode cavity magnonics system. The high light isolation adjusted within a range of different magnetic fields can be obtained by modulating the photon-magnon coupling strength. Due to the simplicity of the device and the system tunability, our results may facilitate potential applications for light magnetic sensing and coherent information processing.
    Language English
    Publishing date 2021-09-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.430619
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Prognostic and predictive significance of the tumor microenvironment in hepatocellular carcinoma.

    Liu, Jibing / Kuang, Shuwen / Zheng, Yiling / Liu, Mei / Wang, Liming

    Cancer biomarkers : section A of Disease markers

    2021  Volume 32, Issue 1, Page(s) 99–110

    Abstract: Background: Identification of molecular markers that reflect the characteristics of the tumor microenvironment (TME) may be beneficial to predict the prognosis of post-operative hepatocellular carcinoma (HCC) patients.: Objective and methods: A total ...

    Abstract Background: Identification of molecular markers that reflect the characteristics of the tumor microenvironment (TME) may be beneficial to predict the prognosis of post-operative hepatocellular carcinoma (HCC) patients.
    Objective and methods: A total of 100 tissue samples from HCC patients were separately stained by immunohistochemistry to examine the expression levels of CD56, CD8α, CD68, FoxP3, CD31 and pan-Keratin. The prognostic values were analyzed by Cox regression and the Kaplan-Meier method.
    Results: Univariate and multivariate logistic analysis showed that FoxP3 was the independent factor associated with microvascular invasion (MVI), tumor size and envelop invasion; CD68 was associated with envelope invasion and AFP. Kaplan-Meier survival curves revealed that CD68 and FoxP3 expression were significantly associated with relapse free survival (RFS) of HCC patients (P< 0.05). The ROC curve indicated that the combination of tumor number, MVI present and CD68 expression yielded a ROC curve area of 82.3% (86.36% specificity, 68.75% sensitivity) to evaluate the prognosis of HCC patients, which was higher than the classifier established by the combination of tumor number and MVI (78.8% probability, 63.64% specificity and 85.42% sensitivity).
    Conclusions: Our study indicated that CD68 and FoxP3 are associated with prognosis of HCC patients, and CD68 can be considered as a potential prognostic and predictive biomarker.
    MeSH term(s) Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/pathology ; Female ; Humans ; Liver Neoplasms/mortality ; Liver Neoplasms/pathology ; Male ; Prognosis ; Survival Analysis ; Tumor Microenvironment
    Language English
    Publishing date 2021-06-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2203517-5
    ISSN 1875-8592 ; 1574-0153 ; 1875-8592
    ISSN (online) 1875-8592 ; 1574-0153
    ISSN 1875-8592
    DOI 10.3233/CBM-203003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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