LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 290

Search options

  1. Article: Editorial: Insights into non-coding RNAs in programmed cell death, from molecular mechanism of tumorigenesis to therapeutic targets.

    Liu, Jinhui / Dong, Peixin

    Frontiers in oncology

    2023  Volume 13, Page(s) 1239782

    Language English
    Publishing date 2023-06-27
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1239782
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: Editorial: Molecular landscapes of human papillomavirus-related squamous cell carcinoma.

    Shen, Yujie / Liu, Jinhui

    Frontiers in oncology

    2023  Volume 13, Page(s) 1215142

    Language English
    Publishing date 2023-05-31
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1215142
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: [Single Kocher-Langenbeck approach combined with anterograde channel screw technique in treatment of acetabular transverse and posterior wall fractures].

    Xu, Xuepeng / Liu, Jinhui / Fei, Lincong / Ye, Junwu

    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery

    2024  Volume 38, Issue 1, Page(s) 35–39

    Abstract: Objective: To assess the effectiveness of the single Kocher-Langenbeck approach combined with anterograde channel screw technique for the treatment of acetabular transverse and posterior wall fractures.: Methods: Between March 2020 and October 2022, ... ...

    Abstract Objective: To assess the effectiveness of the single Kocher-Langenbeck approach combined with anterograde channel screw technique for the treatment of acetabular transverse and posterior wall fractures.
    Methods: Between March 2020 and October 2022, 17 cases of acetabular transverse and posterior wall fractures were treated with the single Kocher-Langenbeck approach combined with anterograde channel screw technique. There were 11 males and 6 females, with an average age of 53.6 years (range, 42-64 years). Causes of injury included traffic accident in 12 cases, and falling from height in 5 cases. The time from injury to operation ranged from 4 to 16 days with an average of 8.8 days. The operation time, intraoperative blood loss, and fluoroscopy frequency were recorded; X-ray films were reviewed regularly after operation to observe the fracture healing, and postoperative complications were recorded. At last follow-up, Matta score was used to evaluate the reduction of fracture, Harris score and modified Merle D'Aubigné-Postel scores system were used to evaluate the hip joint function.
    Results: The operation time was 150-230 minutes (mean, 185.9 minutes), the intraoperative blood loss was 385-520 mL (mean, 446.2 mL), and the fluoroscopy frequency was 18-34 times (mean, 27.5 times). Postoperative fat liquefaction occurred in 1 case and the other incisions healed by first intention; 3 cases had limb numbness after operation, and the symptoms disappeared after active symptomatic treatment; no urogenital system and intestinal injury occurred. All patients were followed up 12-28 months (mean, 19.9 months). Bone union was achieved in all cases with an average healing time of 10.8 weeks (range, 8-14 weeks). There was no complication such as loosening and breakage of internal fixators. At last follow-up, according to Matta score, 12 cases achieved anatomic reduction, 3 satisfactory reduction, and 2 fair reduction, the satisfactory rate was 88.2%; according to Harris hip function score, 12 cases were excellent, 3 good, and 2 fair, the excellent and good rate was 88.2%; according to the modified Merle D'Aubign Aubigné-Postel scoring system, the results were excellent in 11 cases, good in 3 cases, and fair in 3 cases, with an excellent and good rate of 82.4%.
    Conclusion: The single Kocher-Langenbeck approach combined with anterograde channel screw technique is a minimally invasive method for the treatment of acetabular transverse and posterior wall fractures with less complications, simple operation, and satisfactory effectiveness.
    MeSH term(s) Male ; Female ; Humans ; Middle Aged ; Blood Loss, Surgical ; Fracture Fixation, Internal/methods ; Treatment Outcome ; Fractures, Bone/surgery ; Acetabulum/surgery ; Acetabulum/injuries ; Bone Screws ; Hip Fractures/surgery ; Retrospective Studies
    Language Chinese
    Publishing date 2024-01-15
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1420212-8
    ISSN 1002-1892
    ISSN 1002-1892
    DOI 10.7507/1002-1892.202310025
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Exploring the potential mechanism and molecular targets of Taohong Siwu Decoction against deep vein thrombosis based on network pharmacology and analysis docking.

    Fan, Wei / Liu, Jinhui / Liu, Qingyan

    Medicine

    2024  Volume 103, Issue 2, Page(s) e36220

    Abstract: This study aims to investigate the mechanism of Taohong Siwu Decoction (THSWD) against deep vein thrombosis (DVT) using network pharmacology and molecular docking technology. We used the Traditional Chinese Medicine Systems Pharmacology database and ... ...

    Abstract This study aims to investigate the mechanism of Taohong Siwu Decoction (THSWD) against deep vein thrombosis (DVT) using network pharmacology and molecular docking technology. We used the Traditional Chinese Medicine Systems Pharmacology database and reviewed literature to identify the main chemical components of THSWD. To find targets for DVT, we consulted GeneCards, Therapeutic Target Database, and PharmGKB databases. We used Cytoscape 3.8.2 software to construct herb-disease-gene-target networks. Additionally, we integrated drug targets and disease targets on the STRING platform to create a protein-protein interaction network. Then, we conducted Kyoto Encyclopedia of Genes and Genomes and gene ontology analysis. Finally, We employed the molecular docking method to validate our findings. We identified 56 potential targets associated with DVT and found 61 effective components. beta-sitosterol, quercetin, and kaempferol were the most prominent among these components. Our analysis of the protein-protein interaction network revealed that IL6, L1B, and AKT1 had the highest degree of association. Gene ontology analysis showed that THSWD treatment for DVT may involve response to inorganic substances, negative regulation of cell differentiation, plasma membrane protein complex, positive regulation of phosphorylation, and signaling receptor regulator activity. Kyoto Encyclopedia of Genes and Genomes analysis indicated that lipid and atherosclerosis, pathways in cancer, as well as the PI3K-Akt pathway are the main signal pathways involved. Molecular docking results demonstrated strong binding affinity between beta-sitosterol, quercetin, kaempferol, and AKT1 proteins as well as IL1B and IL6 proteins. The main targets for THSWD treatment of DVT may include AKT1, IL1B, and IL6. Beta-sitosterol, quercetin, and kaempferol may be the active ingredients responsible for producing this effect. These compounds may slow down the progression of DVT by regulating the inflammatory response through the PI3K/Akt pathway.
    MeSH term(s) Humans ; Kaempferols/pharmacology ; Kaempferols/therapeutic use ; Network Pharmacology ; Interleukin-6 ; Molecular Docking Simulation ; Phosphatidylinositol 3-Kinases ; Proto-Oncogene Proteins c-akt ; Quercetin ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Venous Thrombosis/drug therapy
    Chemical Substances Taohong Siwu decoction II ; Kaempferols ; Interleukin-6 ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; Quercetin (9IKM0I5T1E) ; Drugs, Chinese Herbal
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000036220
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Group B Streptococcus: Virulence Factors and Pathogenic Mechanism.

    Liu, Yuxin / Liu, Jinhui

    Microorganisms

    2022  Volume 10, Issue 12

    Abstract: Group B Streptococcus (GBS) ... ...

    Abstract Group B Streptococcus (GBS) or
    Language English
    Publishing date 2022-12-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms10122483
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: H

    Li, Aiting / Chen, Yanhui / Hu, Yun / Liu, Dazhi / Liu, Jinhui

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 1852

    Abstract: Formula: see text] state estimation is addressed for continuous-time neural networks in the paper. The norm-bounded uncertainties are considered in communication neural networks. For the considered neural networks with uncertainties, a reduced-order [ ... ...

    Abstract [Formula: see text] state estimation is addressed for continuous-time neural networks in the paper. The norm-bounded uncertainties are considered in communication neural networks. For the considered neural networks with uncertainties, a reduced-order [Formula: see text] state estimator is designed, which makes that the error dynamics is exponentially stable and has weighted [Formula: see text] performance index by Lyapunov function method. Moreover, it is also given the devised method of the reduced-order [Formula: see text] state estimator. Then, considering that sampling the output y(t) of the neural network at every moment will result in waste of excess resources, the event-triggered sampling strategy is used to solve the oversampling problem. In addition, a devised method is also given for the event-triggered reduced-order [Formula: see text] state estimator. Finally, by the well-known Tunnel Diode Circuit example, it shows that a lower order state estimator can be designed under the premise of maintaining the same weighted [Formula: see text] performance index, and using the event-triggered sampling method can reduce the computational and time costs and save communication resources.
    Language English
    Publishing date 2024-01-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-52209-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article: Editorial: The use of data mining in radiological-pathological images for personal medicine.

    Wang, Jincheng / Zhang, Xudong / Liu, Jinhui / Yin, Yin

    Frontiers in genetics

    2023  Volume 14, Page(s) 1187040

    Language English
    Publishing date 2023-03-27
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2023.1187040
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article: Editorial: Multi-omics analysis in tumor microenvironment and tumor heterogeneity.

    Shi, Yuxin / Zhang, Qinglin / Mei, Jie / Liu, Jinhui

    Frontiers in genetics

    2023  Volume 14, Page(s) 1271295

    Language English
    Publishing date 2023-08-23
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2023.1271295
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Transcriptome and single-cell sequencing analysis in tumor microenvironment.

    Liu, Jinhui / Xie, Jiaheng / Dong, Peixin

    The journal of gene medicine

    2023  Volume 25, Issue 10, Page(s) e3520

    MeSH term(s) Transcriptome ; Tumor Microenvironment/genetics ; Gene Expression Profiling
    Language English
    Publishing date 2023-04-27
    Publishing country England
    Document type Editorial
    ZDB-ID 1458024-x
    ISSN 1521-2254 ; 1099-498X
    ISSN (online) 1521-2254
    ISSN 1099-498X
    DOI 10.1002/jgm.3520
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Editorial: Transcriptome analysis in tumor microenvironment and tumor heterogeneity.

    Liu, Jinhui / Xie, Jiaheng / Dong, Peixin

    Oncology research

    2023  Volume 32, Issue 1, Page(s) 99–100

    MeSH term(s) Humans ; Tumor Microenvironment/genetics ; Gene Expression Profiling ; Neoplasms/genetics
    Language English
    Publishing date 2023-11-15
    Publishing country United States
    Document type Editorial
    ZDB-ID 1114699-0
    ISSN 1555-3906 ; 0965-0407
    ISSN (online) 1555-3906
    ISSN 0965-0407
    DOI 10.32604/or.2023.045719
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top