Article ; Online: Stellate ganglion block reduces symptoms of Long COVID: A case series.
2021 Volume 362, Page(s) 577784
Abstract: After recovering from COVID-19, a significant proportion of symptomatic and asymptomatic individuals develop Long COVID. Fatigue, orthostatic intolerance, brain fog, anosmia, and ageusia/dysgeusia in Long COVID resemble "sickness behavior," the autonomic ...
| Abstract | After recovering from COVID-19, a significant proportion of symptomatic and asymptomatic individuals develop Long COVID. Fatigue, orthostatic intolerance, brain fog, anosmia, and ageusia/dysgeusia in Long COVID resemble "sickness behavior," the autonomic nervous system response to pro-inflammatory cytokines (Dantzer et al., 2008). Aberrant network adaptation to sympathetic/parasympathetic imbalance is expected to produce long-standing dysautonomia. Cervical sympathetic chain activity can be blocked with local anesthetic, allowing the regional autonomic nervous system to "reboot." In this case series, we successfully treated two Long COVID patients using stellate ganglion block, implicating dysautonomia in the pathophysiology of Long COVID and suggesting a novel treatment. |
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| MeSH term(s) | Adult ; Autonomic Nerve Block/methods ; COVID-19/complications ; COVID-19/surgery ; Female ; Humans ; SARS-CoV-2 ; Stellate Ganglion/surgery ; Post-Acute COVID-19 Syndrome | |||||
| Language | English | |||||
| Publishing date | 2021-12-08 | |||||
| Publishing country | Netherlands | |||||
| Document type | Case Reports ; Journal Article | |||||
| ZDB-ID | 8335-5 | |||||
| ISSN | 1872-8421 ; 0165-5728 | |||||
| ISSN (online) | 1872-8421 | |||||
| ISSN | 0165-5728 | |||||
| DOI | 10.1016/j.jneuroim.2021.577784 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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