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  1. Book ; Thesis: Structural and functional analyses of microtubule nucleation

    Liu, Peng

    2020  

    Author's details Peng Liu
    Subject code 570
    Language English
    Size IX, 108 Seiten, Illustrationen, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Heidelberg, 2020
    HBZ-ID HT020623281
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Molecular Design and Controlled Self-Assembly of Copolymers as Core-Shell-Corona Nanoparticles for Smarter Tumor Treatment.

    Liu, Peng

    Langmuir : the ACS journal of surfaces and colloids

    2024  Volume 40, Issue 2, Page(s) 1143–1149

    Abstract: Copolymer-based core-shell-corona nanoparticles have attracted more interest for tumor chemotherapy, owing to their unique multifunctionality benefiting from their unique multilevel topological structure in comparison with the conventional core-shell ... ...

    Abstract Copolymer-based core-shell-corona nanoparticles have attracted more interest for tumor chemotherapy, owing to their unique multifunctionality benefiting from their unique multilevel topological structure in comparison with the conventional core-shell ones. Here, the recent progress in such core-shell-corona nanoparticle-based drug delivery systems (DDSs) in tumor chemotherapy was reviewed, focusing on additive functionality of the shell layer for controlled drug release performance from the viewpoints of the molecular design and controlled self-assembly, such as stimuli-responsive gatekeepers, independent loading of active substances, and so on. Moreover, future perspectives have been prospected for smarter tumor treatment.
    MeSH term(s) Humans ; Doxorubicin/chemistry ; Polymers/chemistry ; Neoplasms/drug therapy ; Nanoparticles/chemistry ; Drug Delivery Systems
    Chemical Substances Doxorubicin (80168379AG) ; Polymers
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c02032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Fading beauty: The protein degradation mechanism behind rose petal senescence.

    Liu, Peng

    The Plant cell

    2024  

    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 623171-8
    ISSN 1532-298X ; 1040-4651
    ISSN (online) 1532-298X
    ISSN 1040-4651
    DOI 10.1093/plcell/koae069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: From the archives: On DNA maintenance - SWI/SNF chromatin remodeling complexes, DNA damage repair, and transposon excision repair mechanisms.

    Liu, Peng

    The Plant cell

    2024  

    Language English
    Publishing date 2024-04-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 623171-8
    ISSN 1532-298X ; 1040-4651
    ISSN (online) 1532-298X
    ISSN 1040-4651
    DOI 10.1093/plcell/koae127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Dissecting and redesigning enhancers of photosynthesis genes.

    Liu, Peng

    The Plant cell

    2024  

    Language English
    Publishing date 2024-04-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 623171-8
    ISSN 1532-298X ; 1040-4651
    ISSN (online) 1532-298X
    ISSN 1040-4651
    DOI 10.1093/plcell/koae121
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Machines meet humans on the social road: Risk implications.

    Liu, Peng

    Risk analysis : an official publication of the Society for Risk Analysis

    2023  

    Abstract: Human drivers and machine drivers (i.e., automated vehicles or AVs) will share roads and interact with each other, creating mixed traffic. In this perspective, we develop two mental models about them and their social interactions, aiming to understand ... ...

    Abstract Human drivers and machine drivers (i.e., automated vehicles or AVs) will share roads and interact with each other, creating mixed traffic. In this perspective, we develop two mental models about them and their social interactions, aiming to understand the risk implications of AVs and mixed traffic. Based on Mental Model I (i.e., machine drivers are superior drivers without human weaknesses), many simulation-based safety assessments, which often overlook or oversimplify human-AV social interactions, have predicted significant safety benefits when machine drivers interact with or replace human drivers. In contrast, Mental Model II considers human and machine drivers as heterogeneous and incompatible, suggesting that their interactions may lead to unexpected and occasionally negative outcomes, particularly in imminent mixed traffic. This perspective gains support from recent comparative empirical studies that employ various methods such as survey experiments, driving simulators, test-tracks, on-road observations, and AV accident analysis. These studies provide initial evidence of emerging traffic risks arising from human-AV social interactions, including human drivers' aggression and road rage toward AVs, human drivers exploiting AVs, AVs exerting negative peer influences on human drivers, and their incompatibility increasing human drivers' challenges in joining mixed traffic and thus risky behaviors. We propose specific suggestions to mitigate problematic human-AV social interactions and the associated emerging risks.
    Language English
    Publishing date 2023-11-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 778660-8
    ISSN 1539-6924 ; 0272-4332
    ISSN (online) 1539-6924
    ISSN 0272-4332
    DOI 10.1111/risa.14255
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Polyprodrugs for tumor chemotherapy: from molecular structure to drug release performance.

    Liu, Peng

    Journal of materials chemistry. B

    2023  Volume 11, Issue 40, Page(s) 9565–9571

    Abstract: Polyprodrugs have been recognized as promising carrier-free drug delivery systems (DDSs) for tumor chemotherapy in recent years, showing distinct superiority in comparison with the conventional polymer prodrugs. In the present work, the structure- ... ...

    Abstract Polyprodrugs have been recognized as promising carrier-free drug delivery systems (DDSs) for tumor chemotherapy in recent years, showing distinct superiority in comparison with the conventional polymer prodrugs. In the present work, the structure-property relationship of polyprodrugs was explored from the perspective of molecular structure, by discussing the effects of the conjugations and linkers on their drug content and drug releasing performance, including drug releasing rate and drug releasing selectivity, as well as the anti-tumor performance of the released drugs. Moreover, the future challenges in the design of polyprodrug-based DDSs with high anti-tumor efficacy were also highlighted.
    MeSH term(s) Humans ; Antineoplastic Agents/chemistry ; Drug Liberation ; Molecular Structure ; Drug Delivery Systems ; Prodrugs/chemistry ; Neoplasms/drug therapy
    Chemical Substances Antineoplastic Agents ; Prodrugs
    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2702241-9
    ISSN 2050-7518 ; 2050-750X
    ISSN (online) 2050-7518
    ISSN 2050-750X
    DOI 10.1039/d3tb01700a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Abscisic acid-regulated microRNA biogenesis through HYPONASTIC LEAVES1.

    Liu, Peng

    The Plant cell

    2023  Volume 35, Issue 8, Page(s) 2707–2708

    MeSH term(s) Abscisic Acid/pharmacology ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Arabidopsis/genetics ; Arabidopsis/metabolism ; MicroRNAs/genetics ; Gene Expression Regulation, Plant/genetics
    Chemical Substances Abscisic Acid (72S9A8J5GW) ; Arabidopsis Proteins ; MicroRNAs
    Language English
    Publishing date 2023-05-16
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 623171-8
    ISSN 1532-298X ; 1040-4651
    ISSN (online) 1532-298X
    ISSN 1040-4651
    DOI 10.1093/plcell/koad135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Unlocking the potential: Expanding plastid transformation for beyond-organelle function.

    Liu, Peng

    The Plant cell

    2023  Volume 35, Issue 9, Page(s) 3386–3387

    MeSH term(s) Plastids/genetics ; Genome, Mitochondrial ; Transformation, Genetic
    Language English
    Publishing date 2023-06-23
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 623171-8
    ISSN 1532-298X ; 1040-4651
    ISSN (online) 1532-298X
    ISSN 1040-4651
    DOI 10.1093/plcell/koad179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Uncovering the mechanism of banana "green ripening".

    Liu, Peng

    The Plant cell

    2023  Volume 35, Issue 5, Page(s) 1294–1295

    MeSH term(s) Musa/genetics ; Musa/metabolism ; Transcription Factors/metabolism ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Fruit/metabolism ; Gene Expression Regulation, Plant
    Chemical Substances Transcription Factors ; Plant Proteins
    Language English
    Publishing date 2023-02-16
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 623171-8
    ISSN 1532-298X ; 1040-4651
    ISSN (online) 1532-298X
    ISSN 1040-4651
    DOI 10.1093/plcell/koad048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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