Article ; Online: Genome-wide analysis of runs of homozygosity in Italian Mediterranean buffalo.
2022 Volume 105, Issue 5, Page(s) 4324–4334
Abstract: Runs of homozygosity (ROH) are a powerful tool to explore patterns of genomic inbreeding in animal populations and detect signatures of selection. The present study used ROH analysis to evaluate the genome-wide patterns of homozygosity, inbreeding levels, ...
Abstract | Runs of homozygosity (ROH) are a powerful tool to explore patterns of genomic inbreeding in animal populations and detect signatures of selection. The present study used ROH analysis to evaluate the genome-wide patterns of homozygosity, inbreeding levels, and distribution of ROH islands using the SNP data sets from 899 Mediterranean buffaloes. A total of 42,433 ROH segments were identified, with an average of 47.20 segments per individual. The ROH comprising mostly shorter segments (1-4 Mb) accounted for approximately 72.29% of all ROH. In contrast, the larger ROH (>8 Mb) class accounted for only 7.97% of all ROH segments. Estimated inbreeding coefficients from ROH (F |
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MeSH term(s) | Animals ; Buffaloes/genetics ; Cattle ; Diarrhea/veterinary ; Genotype ; Homozygote ; Inbreeding ; Italy ; Polymorphism, Single Nucleotide ; Quantitative Trait Loci |
Language | English |
Publishing date | 2022-03-17 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 242499-x |
ISSN | 1525-3198 ; 0022-0302 |
ISSN (online) | 1525-3198 |
ISSN | 0022-0302 |
DOI | 10.3168/jds.2021-21543 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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