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  1. Article ; Online: Effects of Social Participation by Middle-Aged and Elderly Residents on the Utilization of Medical Services: Evidence From China.

    Liu, Tai-Yi / Qiu, De-Chao / Chen, Ting

    Frontiers in public health

    2022  Volume 10, Page(s) 824514

    Abstract: Objectives: Aim to evaluate the effect of social participation on utilization of medical services among middle-aged and elderly residents in China.: Methods: We used data from the 2018 wave of the China Health and Retirement Longitudinal Study. ... ...

    Abstract Objectives: Aim to evaluate the effect of social participation on utilization of medical services among middle-aged and elderly residents in China.
    Methods: We used data from the 2018 wave of the China Health and Retirement Longitudinal Study. Social participation is classified into three types. Furthermore, to control for confounding factors, our study computed propensity score matching (PSM) to evaluate the effect of social participation on the utilization of medical services.
    Result: The result of PSM indicates that social participation significantly positively affects the utilization of outpatient services, the average treatment effect on the treated (ATT = 0.038
    Conclusion: Thus, social participation significantly positively affects healthcare utilization by middle-aged and elderly residents. Hence, the government and society should provide more conveniences and promote social participation among middle-aged and elderly residents.
    MeSH term(s) Aged ; China ; Healthcare Disparities ; Humans ; Longitudinal Studies ; Middle Aged ; Patient Acceptance of Health Care ; Social Participation
    Language English
    Publishing date 2022-07-07
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.824514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Trends in Socio-economic Inequality in Smoking Among Middle-aged and Older Adults in China: Evidence From the 2011 and 2018 China Health and Retirement Longitudinal Study.

    Liu, Tai-Yi / Qiu, De-Chao / Song, Fujian / Chen, Ting

    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco

    2022  Volume 25, Issue 1, Page(s) 50–57

    Abstract: Introduction: Socio-economic inequalities in smoking and related health problems are a public health concern worldwide. To support the development of effective tobacco control policies, this study examines trends in smoking rates according to socio- ... ...

    Abstract Introduction: Socio-economic inequalities in smoking and related health problems are a public health concern worldwide. To support the development of effective tobacco control policies, this study examines trends in smoking rates according to socio-economic status (SES) in China.
    Aims and methods: We analyzed data from repeated cross-sectional China Health and Retirement Longitudinal Study (CHARLS) on adults aged ≥45 years for the years 2011 and 2018, which involved 16 471 participants in 2011 and 19 367 in 2018. We then estimated the SES of individuals based on four types of wealth-related variables, namely, education, occupation, household characteristics, and durable consumer goods. Principal-component analysis was conducted to measure SES, and the Erreygers normalised concentration index (ECI) was used to calculate socio-economic inequality in current smoking by gender, age, and region.
    Results: The overall ECI (95% confidence interval) for women was -0.042 (-0.054 to -0.031) and -0.038 (-0.047 to -0.029) for 2011 and 2018, respectively. The ECI (95% confidence interval) for men was -0.077 (-0.101 to -0.050) and -0.019 (-0.042 to 0.005) for 2011 and 2018, respectively. The inequality in smoking by SES for adults aged < 60 years in the Northeast region increased during 2011-2018, from -0.069 (-0.144 to 0.006) to -0.119 (-0.199 to -0.038) for women and from 0.009 (-0.115 to 0.132) to -0.164 (-0.296 to -0.032) for men.
    Conclusions: smoking inequality by socio-economic among adults aged ≥45 years declined in recent years in China. However, smoking inequality by SES increased in other population groups.
    Implications: Our research indicated that socio-economic inequality of current smoking among residents aged 45 years and older declined in 2018 when compared with 2011 numbers, particularly for men aged ≥ 60 years. Women in the Northeast region displayed more significant smoking inequality by SES than women in other regions did. During the study period, there was an increase in inequality in smoking by SES for adults aged < 60 years in the Northeast region. Thus, tobacco control policies and interventions should be targeted at high-risk subpopulations with lower SES, particularly in Northeast China.
    MeSH term(s) Middle Aged ; Male ; Humans ; Female ; Aged ; Retirement ; Socioeconomic Factors ; Longitudinal Studies ; Cross-Sectional Studies ; Tobacco Smoking/epidemiology ; China/epidemiology ; Social Class
    Language English
    Publishing date 2022-06-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1452315-2
    ISSN 1469-994X ; 1462-2203
    ISSN (online) 1469-994X
    ISSN 1462-2203
    DOI 10.1093/ntr/ntac158
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Trends in the distribution of socioeconomic inequalities in smoking and cessation: evidence among adults aged 18 ~ 59 from China Family Panel Studies data.

    Huang, Ming Zhao / Liu, Tai Yi / Zhang, Zhong Min / Song, Fujian / Chen, Ting

    International journal for equity in health

    2023  Volume 22, Issue 1, Page(s) 86

    Abstract: Introduction: Cigarette smoking is usually more prevalent among those with a lower socioeconomic status (SES), which can be driven by inequalities in the initiation and cessation of smoking, giving rise to SES disparities in health. This study aimed to ... ...

    Abstract Introduction: Cigarette smoking is usually more prevalent among those with a lower socioeconomic status (SES), which can be driven by inequalities in the initiation and cessation of smoking, giving rise to SES disparities in health. This study aimed to gauge the SES inequalities in smoking related behaviours and their evolving trends based on a nationally representative database.
    Method: Data were extracted from repeated cross-sectional China Family Panel Studies (CFPS) of adults aged ≥18 and <60 years in 2012, 2014, 2016 and 2018. SES was constructed by principal component analysis based on income, education and occupation. Regression-based odds ratios and coefficients as the relative effect index of inequality were applied to quantify the degree of socioeconomic inequality in smoking related behaviours and to adjust for possible confounding factors. Multivariable regressions were utilized to explore the temporal trends in smoking inequalities.
    Results: The smoking prevalence among men decreased from 61.16% to 2012 to 57.88% in 2018, cigarette consumption among current smokers declined from 16.71 to 15.49 cigs/per day, and the cessation rate increased from 17.55% to 24.08%. Cigarette consumption for women decreased from 13.39 in 2012 to 11.01 cigs/per day in 2018. Smoking prevalence showed significant SES inequalities among men and women from 2012 to 2018 (men: OR
    Conclusion: The smoking prevalence declined between 2012 and 2018 in China. However, SES inequalities in smoking persist, while socioeconomic inequalities in smoking were not alleviated among adults aged 18 ~ 59 in China. Tobacco control measures should be implemented by giving more attention to people with lower SES who are more vulnerable to tobacco use.
    MeSH term(s) Male ; Adult ; Humans ; Female ; Socioeconomic Factors ; Cross-Sectional Studies ; Health Behavior ; Cigarette Smoking ; Prevalence ; China/epidemiology
    Language English
    Publishing date 2023-05-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2092056-8
    ISSN 1475-9276 ; 1475-9276
    ISSN (online) 1475-9276
    ISSN 1475-9276
    DOI 10.1186/s12939-023-01898-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Correction: Clinical-mediated discovery of pyroptosis in CD8

    Zhang, Ying / Bai, Yun / Ma, Xiao-Xuan / Song, Jian-Kun / Luo, Yue / Fei, Xiao-Ya / Ru, Yi / Luo, Ying / Jiang, Jing-Si / Zhang, Zhan / Yang, Dan / Xue, Ting-Ting / Zhang, Hui-Ping / Liu, Tai-Yi / Xiang, Yan-Wei / Kuai, Le / Liu, Ye-Qiang / Li, Bin

    Cell death & disease

    2024  Volume 15, Issue 2, Page(s) 164

    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2541626-1
    ISSN 2041-4889 ; 2041-4889
    ISSN (online) 2041-4889
    ISSN 2041-4889
    DOI 10.1038/s41419-023-06366-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Prognostic Nomogram for Liver Metastatic Colon Cancer Based on Histological Type, Tumor Differentiation, and Tumor Deposit: A TRIPOD Compliant Large-Scale Survival Study.

    Kuai, Le / Zhang, Ying / Luo, Ying / Li, Wei / Li, Xiao-Dong / Zhang, Hui-Ping / Liu, Tai-Yi / Yin, Shuang-Yi / Li, Bin

    Frontiers in oncology

    2021  Volume 11, Page(s) 604882

    Abstract: Objective: A proportional hazard model was applied to develop a large-scale prognostic model and nomogram incorporating clinicopathological characteristics, histological type, tumor differentiation grade, and tumor deposit count to provide clinicians ... ...

    Abstract Objective: A proportional hazard model was applied to develop a large-scale prognostic model and nomogram incorporating clinicopathological characteristics, histological type, tumor differentiation grade, and tumor deposit count to provide clinicians and patients diagnosed with colon cancer liver metastases (CLM) a more comprehensive and practical outcome measure.
    Methods: Using the Transparent Reporting of multivariable prediction models for individual Prognosis or Diagnosis (TRIPOD) guidelines, this study identified 14,697 patients diagnosed with CLM from 1975 to 2017 in the Surveillance, Epidemiology, and End Results (SEER) 21 registry database. Patients were divided into a modeling group (n=9800), an internal validation group (n=4897) using computerized randomization. An independent external validation cohort (n=60) was obtained. Univariable and multivariate Cox analyses were performed to identify prognostic predictors for overall survival (OS). Subsequently, the nomogram was constructed, and the verification was undertaken by receiver operating curves (AUC) and calibration curves.
    Results: Histological type, tumor differentiation grade, and tumor deposit count were independent prognostic predictors for CLM. The nomogram consisted of age, sex, primary site, T category, N category, metastasis of bone, brain or lung, surgery, and chemotherapy. The model achieved excellent prediction power on both internal (mean AUC=0.811) and external validation (mean AUC=0.727), respectively, which were significantly higher than the American Joint Committee on Cancer (AJCC) TNM system.
    Conclusion: This study proposes a prognostic nomogram for predicting 1- and 2-year survival based on histopathological and population-based data of CLM patients developed using TRIPOD guidelines. Compared with the TNM stage, our nomogram has better consistency and calibration for predicting the OS of CLM patients.
    Language English
    Publishing date 2021-10-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2021.604882
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Clinical-mediated discovery of pyroptosis in CD8

    Zhang, Ying / Bai, Yun / Ma, Xiao-Xuan / Song, Jian-Kun / Luo, Yue / Fei, Xiao-Ya / Ru, Yi / Luo, Ying / Jiang, Jing-Si / Zhang, Zhan / Yang, Dan / Xue, Ting-Ting / Zhang, Hui-Ping / Liu, Tai-Yi / Xiang, Yan-Wei / Kuai, Le / Liu, Ye-Qiang / Li, Bin

    Cell death & disease

    2023  Volume 14, Issue 8, Page(s) 553

    Abstract: Histologically, melanoma tissues had fewer positive cells percentage of pyroptosis-related genes (PRGs), GZMA, GSDMB, NLRP1, IL18, and CHMP4A in epidermal than in normal skin. Pyroptosis, a new frontier in cancer, affects the tumor microenvironment and ... ...

    Abstract Histologically, melanoma tissues had fewer positive cells percentage of pyroptosis-related genes (PRGs), GZMA, GSDMB, NLRP1, IL18, and CHMP4A in epidermal than in normal skin. Pyroptosis, a new frontier in cancer, affects the tumor microenvironment and tumor immunotherapy. Nevertheless, the role of pyroptosis remains controversial, which reason is partly due to the heterogeneity of the cellular composition in melanoma. In this study, we present a comprehensive analysis of the single-cell transcriptome landscape of pyroptosis in melanoma specimens. Our findings reveal dysregulation in the expression of PRGs, particularly in immune cells, such as CD8
    MeSH term(s) Humans ; CD8-Positive T-Lymphocytes ; Pyroptosis/genetics ; Melanoma/genetics ; Skin Neoplasms/genetics ; Killer Cells, Natural ; Tumor Microenvironment
    Language English
    Publishing date 2023-08-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2541626-1
    ISSN 2041-4889 ; 2041-4889
    ISSN (online) 2041-4889
    ISSN 2041-4889
    DOI 10.1038/s41419-023-06068-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Gene set enrichment analysis and ingenuity pathway analysis to identify biomarkers in Sheng-ji Hua-yu formula treated diabetic ulcers

    Ru, Yi / Zhang, Ying / Xiang, Yan-wei / Luo, Ying / Luo, Yue / Jiang, Jing-si / Song, Jian-kun / Fei, Xiao-ya / Yang, Dan / Zhang, Zhan / Zhang, Hui-ping / Liu, Tai-yi / Yin, Shuang-yi / Li, Bin / Kuai, Le

    Journal of ethnopharmacology. 2022 Mar. 01, v. 285

    2022  

    Abstract: Sheng-ji Hua-yu (SJHY) formula is a Chinese herbal prescription for diabetic ulcers (DUs) treatment, which can accelerate wound reconstruction and shorten the healing time. However, its mechanism role maintains unclear.To elucidate the molecular ... ...

    Abstract Sheng-ji Hua-yu (SJHY) formula is a Chinese herbal prescription for diabetic ulcers (DUs) treatment, which can accelerate wound reconstruction and shorten the healing time. However, its mechanism role maintains unclear.To elucidate the molecular mechanisms of SJHY application on DUs.To begin with, transcriptome sequencing was adopted to identified differentially expression mRNAs among normal ulcers, DUs, and DUs + SJHY treatment in vivo. Liquid chromatography-tandem mass spectrometry was applied for the quality control of SJHY formula. GO and KEGG enrichment analysis were used to identify the mechanisms underlying the therapeutic effect of SJHY formula, and then gene set enrichment analysis and ingenuity pathway analysis were conducted for functional analysis. Further, qPCR detection was performed in vivo for validation.SJHY administration could regulate the glucose metabolic process, AMPK and HIF-1 pathway to accelerate healing processes of DUs. Besides, CRHR1, SHH, and GAL were identified as the critical targets, and SLC6A3, GRP, FGF23, and CYP27B1 were considered as the upstream genes of SJHY treatment. Combined with animal experiments, the prediction results were validated in DUs mice model.This study used modular pharmacology analysis to identify the biomarkers of SJHY formula and provide the potential therapeutic targets for DUs treatment as well.
    Keywords biomarkers ; genes ; glucose ; liquid chromatography ; pharmacology ; prediction ; quality control ; tandem mass spectrometry ; therapeutics ; traditional medicine ; transcriptome
    Language English
    Dates of publication 2022-0301
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2021.114845
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Environmental Sustainability Approaches Adopted for Anhsin Bridge Construction of Ankeng Metro System in New Taipei City in Taiwan

    Liu Tai-Yi / Chen Po-Han / Chou Nelson N.S. / Chou Mao-Yi / Lin Jui-Jiun / Lo Han-Ting

    E3S Web of Conferences, Vol 117, p

    2019  Volume 00013

    Abstract: The Ankeng Light Rail Metro System (ALRMS) is a Design-Build (DB) construction project located in New Taipei City. The Anhsin Bridge (AB) is one of the major parts of ALRMS. The original concept from the client, the Department of Rapid Transit Systems ( ... ...

    Abstract The Ankeng Light Rail Metro System (ALRMS) is a Design-Build (DB) construction project located in New Taipei City. The Anhsin Bridge (AB) is one of the major parts of ALRMS. The original concept from the client, the Department of Rapid Transit Systems (DRTS), New Taipei City Government, was to design Anhsin Bridge as a steel arch bridge, which inevitably would require construction of some piers in the river reservation zone. Also, a temporary access bridge would be necessary during the erection of the steel frame. All these would pose a harmful situation for the river flow. Considering environmental sustainability, the contractor proposed a sustainable construction method, the unbalanced cable-stayed design with truss frames (UBCSTF), to build the Anhsin Bridge. Without constructing piers in the river reservation zone, the pylon of the Anhsin Bridge was laid on a 5.5m thickness foundation supported by 42 2m-diameter bored piles. A friendly environmental achievement was made by adopting UBCSTF. In this paper, the authors will share the rare construction experiences with the Anhsin Bridge construction, and present the detailed design concept, construction, and environmental sustainability achievements in this project.
    Keywords Environmental sciences ; GE1-350
    Subject code 690
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Tartary buckwheat protein prevented dyslipidemia in high-fat diet-fed mice associated with gut microbiota changes.

    Zhou, Xiao-Li / Yan, Bei-Bei / Xiao, Ying / Zhou, Yi-Ming / Liu, Tai-Yi

    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

    2018  Volume 119, Page(s) 296–301

    Abstract: As one of low-digestible proteins, tartary buckwheat protein (BWP) revealed a cholesterol-lowering activity. The relationship between the prevention of BWP on dyslipidemia and changes in the numbers of gut microbiota was investigated. The male C57BL/6 ... ...

    Abstract As one of low-digestible proteins, tartary buckwheat protein (BWP) revealed a cholesterol-lowering activity. The relationship between the prevention of BWP on dyslipidemia and changes in the numbers of gut microbiota was investigated. The male C57BL/6 mice were separately fed on normal diet, high-fat diet (HFD) with casein, and HFD with BWP extract for 6 weeks. Quantitative PCR assay was applied to quantify the microbiota composition in feces. The levels of plasma total cholesterol (TC) and triglyceride (TG) in the mice fed on HFD with BWP were significantly lower than those on HFD with casein. BWP promoted the growth of Lactobacillus, Bifidobacterium and Enterococcus and inhibited the growth of Escherichia coli in HFD-fed mice. Moreover, Bifidobacterium population was closely related to contents of plasma lipids. Further, BWP significantly decreased the levels of plasma inflammation factors as induced by HFD, including lipopolysaccharide, tumor necrosis factor α and interleukin 6. BWP significantly increased the excretion of total bile acids and short-chain fatty acids in feces. In conlusion, BWP benefited cholesterol metabolism, which could be attributed to regulating composition of gut microbiota.
    MeSH term(s) Animals ; Bacteria/isolation & purification ; Cytokines/metabolism ; Diet, High-Fat/adverse effects ; Fagopyrum/chemistry ; Fatty Acids, Volatile/analysis ; Feces/chemistry ; Gastrointestinal Microbiome ; Hyperlipidemias/prevention & control ; Inflammation/prevention & control ; Inflammation Mediators/metabolism ; Lipids/blood ; Male ; Mice, Inbred C57BL ; Plant Proteins/therapeutic use
    Chemical Substances Cytokines ; Fatty Acids, Volatile ; Inflammation Mediators ; Lipids ; Plant Proteins
    Language English
    Publishing date 2018-02-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 782617-5
    ISSN 1873-6351 ; 0278-6915
    ISSN (online) 1873-6351
    ISSN 0278-6915
    DOI 10.1016/j.fct.2018.02.052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The Identification of the Biomarkers of Sheng-Ji Hua-Yu Formula Treated Diabetic Wound Healing Using Modular Pharmacology.

    Jiang, Jing-Si / Zhang, Ying / Luo, Ying / Ru, Yi / Luo, Yue / Fei, Xiao-Ya / Song, Jian-Kun / Ding, Xiao-Jie / Zhang, Zhan / Yang, Dan / Yin, Shuang-Yi / Zhang, Hui-Ping / Liu, Tai-Yi / Li, Bin / Kuai, Le

    Frontiers in pharmacology

    2021  Volume 12, Page(s) 726158

    Abstract: Sheng-Ji Hua-Yu (SJHY) formula has been proved to reduce the severity of diabetic wound healing without significant adverse events in our previous clinical trials. However, based on multi-target characteristics, the regulatory network among herbs, ... ...

    Abstract Sheng-Ji Hua-Yu (SJHY) formula has been proved to reduce the severity of diabetic wound healing without significant adverse events in our previous clinical trials. However, based on multi-target characteristics, the regulatory network among herbs, ingredients, and hub genes remains to be elucidated. The current study aims to identify the biomarkers of the SJHY formula for the treatment of diabetic wound healing. First, a network of components and targets for the SJHY formula was constructed using network pharmacology. Second, the ClusterONE algorithm was used to build a modular network and identify hub genes along with kernel pathways. Third, we verified the kernel targets by molecular docking to select hub genes. In addition, the biomarkers of the SJHY formula were validated by animal experiments in a diabetic wound healing mice model. The results revealed that the SJHY formula downregulated the mRNA expression of
    Language English
    Publishing date 2021-11-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2021.726158
    Database MEDical Literature Analysis and Retrieval System OnLINE

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