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  1. Article ; Online: All-dielectric high-NA achromatic metalenses in the mid-infrared band based on subregions.

    Wang, Zhiheng / Liu, Weiguo / Zhu, Yechuan / Zhou, Shun

    Applied optics

    2024  Volume 63, Issue 9, Page(s) 2241–2247

    Abstract: For conventional refractive lenses, chromatic aberration inevitably occurs due to the refractive index variation of the lens material with the incident wavelength, leading to axial aberrations and lower imaging system quality. Achromatic metalenses have ... ...

    Abstract For conventional refractive lenses, chromatic aberration inevitably occurs due to the refractive index variation of the lens material with the incident wavelength, leading to axial aberrations and lower imaging system quality. Achromatic metalenses have demonstrated a great capability to solve this problem and been extensively investigated. However, the metalens achromatic method involves construction of a unit structure satisfying a phase distribution greater than 0-2
    Language English
    Publishing date 2024-04-03
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.510342
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The global, regional, and national disease burden of breast cancer attributable to tobacco from 1990 to 2019: a global burden of disease study.

    Guo, Qiusheng / Lu, Yunyan / Liu, Weiguo / Lan, Gaochen / Lan, Tian

    BMC public health

    2024  Volume 24, Issue 1, Page(s) 107

    Abstract: Objective: Tobacco has been identified as a significant contributory element to the development of breast cancer. Our objective was to evaluate the spatiotemporal trends of tobacco-related breast cancer at the global, regional, and national scales ... ...

    Abstract Objective: Tobacco has been identified as a significant contributory element to the development of breast cancer. Our objective was to evaluate the spatiotemporal trends of tobacco-related breast cancer at the global, regional, and national scales during 1990-2019.
    Methods: We extracted data on mortality, disability adjusted of life years (DALYs), age-standardized mortality rate (ASMR), and age-standardized DALYs rate (ASDR) from the Global Burden of Disease (GBD) study 2019. Estimated annual percentage change (EAPC) was computed to assess the temporal change in ASDR and ASMR.
    Results: In 2019, the deaths and DALYs attributed to tobacco-related breast cancer were estimated to be 35,439 (95% UI: 22,179-48,119) and 1,060,590 (95% UI: 622,550-1,462,580), respectively. These figures accounted for 5.1% and 5.2% of the total burden of breast cancer. ASMR and ASDR increased in low SDI regions, remained stable in low-middle and middle SDI regions and declined in high and high-middle SDI regions. The burden of breast cancer attributable to tobacco varied notably among regions and nations. Oceania, Southern Latin America, and Central Europe were the GBD regions with the highest number of ASMR and DALYs. There was a positive relationship between age-standardized rate and SDI value in 2019 across 204 nations or territories. A negative association was observed between the EAPC in ASMR or ASDR and the human development index (HDI) in 2019 (R = -0.55, p < 0.01 for ASMR; R = -0.56, p < 0.01 for ASDR).
    Conclusion: Tobacco is one important and modifiable risk factor for breast cancer. The heterogeneity in both the spatial and temporal distribution can be attributed to factors such as aging, population growth, and SDI. These findings substantiate the necessity of expediting the enforcement of tobacco-free legislation in order to safeguard populations from the detrimental effects of tobacco.
    MeSH term(s) Humans ; Female ; Breast Neoplasms/epidemiology ; Breast Neoplasms/etiology ; Global Burden of Disease ; Cost of Illness ; Breast ; Tobacco Products
    Language English
    Publishing date 2024-01-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-17405-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Correlation between the MNCD classification-based staging of Parkinson's disease and quality of life: a cross-sectional study.

    He, Guixiang / Ren, Jingru / Shi, Haicun / Liu, Weiguo / Lu, Ming

    Journal of neural transmission (Vienna, Austria : 1996)

    2024  Volume 131, Issue 4, Page(s) 315–322

    Abstract: Parkinson's disease (PD) is a highly heterogeneous neurodegenerative disorder with varying clinical subtypes. Recently, a novel classification called MNCD (Motor/Non-motor/Cognition/Dependency) has been proposed, which can also include staging based on ... ...

    Abstract Parkinson's disease (PD) is a highly heterogeneous neurodegenerative disorder with varying clinical subtypes. Recently, a novel classification called MNCD (Motor/Non-motor/Cognition/Dependency) has been proposed, which can also include staging based on disease severity. We aim to investigate which staging, the MNCD classification and staging or Hoehn and Yahr (H&Y) staging, exhibits a stronger correlation with the 39-item Parkinson's Disease Questionnaire (PDQ-39). In a cross-sectional study conducted at our single center, 357 PD patients were recruited. Data encompassed scores from various assessments such as the Movement Disorder Society of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Parts I, II, III and IV, Montreal Cognitive Assessment (MoCA), PDQ-39, and the H&Y scale. The mean age of these patients was 66.4 ± 9.1 years old, and the majority (54.6%) were male. MNCD stages: stage 1 (N = 3, 0.8%), stage 2 (N = 62, 17.4%), stage 3 (N = 187, 52.4%), stage 4 (N = 86, 24.1%), and stage 5 (N = 19, 5.3%). The top 5 most frequent PD-related clinical symptoms were sleep disturbances (89.6%), fatigue (69.7%), mild cognitive impairment (68.9%), constipation (65.8%), and postural instability (65.5%). The PDQ-39 demonstrated a positive correlation with both MNCD staging and H&Y staging. Moreover, the MNCD staging exhibited a stronger correlation with PDQ-39 compared to H&Y staging. The correlation between the MNCD classification and staging with the quality of life in PD patients is more statistically significant compared to the H&Y staging.
    MeSH term(s) Humans ; Male ; Female ; Middle Aged ; Aged ; Parkinson Disease/diagnosis ; Quality of Life/psychology ; Cross-Sectional Studies ; Severity of Illness Index ; Fatigue
    Language English
    Publishing date 2024-03-28
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 184163-4
    ISSN 1435-1463 ; 0300-9564
    ISSN (online) 1435-1463
    ISSN 0300-9564
    DOI 10.1007/s00702-024-02756-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Similarities and differences in the rhizosphere biota among different ephemeral desert plants in Gurbantünggüt Desert

    Yang, Yang / Liu, Weiguo / Huang, Tingwen / Yang, Yaru

    Environ Sci Eur 2023 Dec., v. 35, no. 1, p. 18

    2023  , Page(s) 18

    Abstract: BACKGROUND: The interactions between rhizosphere microbial community and ephemeral desert plants strongly affect the ecological protection, restoration and reconstruction in deserts. Ephemeral desert plants as the pioneer plants in the succession are ... ...

    Abstract BACKGROUND: The interactions between rhizosphere microbial community and ephemeral desert plants strongly affect the ecological protection, restoration and reconstruction in deserts. Ephemeral desert plants as the pioneer plants in the succession are widely distributed in deserts. However, how the ephemeral desert plants assemble their rhizosphere microbiota to adapt to arid and semi-arid environments has been little explored. Here, we used high-throughput sequencing techniques to compare rhizosphere bacterial communities and functions with different ephemeral desert plants composition from Gurbantünggüt Desert in western China. RESULTS: These plants had the same dominant bacterial phyla, which approximately counted 98% of the total bacterial communities. But the bacterial communities had significant differences (P < 0.05) in the composition, structure, diversity and functions of all groups. When comparing every two groups, similarities appeared in the composition, structure and functions of rhizosphere microbiota, and within each group, it is more likely that the rhizosphere bacterial communities of closely related ephemeral desert plants tend to be consistent. Additionally, the rhizosphere bacterial taxa had more similarities in predicted functions. And the predicted functions were correlated with the dominant bacterial phyla. CONCLUSIONS: Overall, to adapt to the arid and semi-arid environments, the rhizosphere bacterial communities of ephemeral desert plants appear similarities based on having differences. This finding will help to understand the importance of how plants and soil microorganisms cooperate in the process of adaption to arid and semi-arid environments.
    Keywords microbial communities ; microorganisms ; rhizosphere ; soil ; China
    Language English
    Dates of publication 2023-12
    Size p. 18
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    Note Use and reproduction
    ZDB-ID 2593962-2
    ISSN 2190-4715
    ISSN 2190-4715
    DOI 10.1186/s12302-023-00724-5
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Clinical effects and biological mechanisms of exercise on lumbar disc herniation.

    Wang, Ziwen / Liu, Xindai / Gao, Ke / Tuo, Haowen / Zhang, Xinxin / Liu, Weiguo

    Frontiers in physiology

    2024  Volume 15, Page(s) 1309663

    Abstract: Lumbar Disc Herniation (LDH) is a syndrome in which lumbar disc degeneration, rupture of the annulus fibrosus, and herniation of the nucleus pulposus irritate and compress the nerve roots and cauda equina, resulting in the main manifestations of lumbar ... ...

    Abstract Lumbar Disc Herniation (LDH) is a syndrome in which lumbar disc degeneration, rupture of the annulus fibrosus, and herniation of the nucleus pulposus irritate and compress the nerve roots and cauda equina, resulting in the main manifestations of lumbar pain and/or lower extremity pain. There is evidence in various clinical areas that exercise is effective in treating LDH, and exercise intervention for more than 2 weeks reduces disease activity in LDH. However, the mechanism of exercise's action in reducing disease activity in LDH is unclear. In this article, we first summarize and highlight the effectiveness of exercise in treating LDH and provide guideline recommendations regarding exercise type, intensity, frequency, and duration. Then, we integrate the existing evidence and propose biological mechanisms for the potential effects of exercise on neuromechanical compression, inflammatory chemical stimuli, and autoimmune responses from the perspective of LDH pathogenesis as an entry point. However, a large body of evidence was obtained from non-LDH populations. Future research needs to investigate further the proposed biological mechanisms of exercise in reducing disease activity in LDH populations. This knowledge will contribute to the basic science and strengthen the scientific basis for prescribing exercise therapy for the routine clinical treatment of LDH.
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2024.1309663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Combined transcriptomics and metabolomics to analyse the response of Cuminum cyminum L. under Pb stress.

    Yang, Xinlong / Chen, Yinguang / Liu, Weiguo / Huang, Tingwen / Yang, Yang / Mao, Yuqing / Meng, Yao

    The Science of the total environment

    2024  Volume 923, Page(s) 171497

    Abstract: Lead (Pb) can disrupt plant gene expression, modify metabolite contents, and influence the growth of plants. Cuminum cyminum L. is highly adaptable to adversity, but molecular mechanism by which it responds to Pb stress is unknown. For this study, ... ...

    Abstract Lead (Pb) can disrupt plant gene expression, modify metabolite contents, and influence the growth of plants. Cuminum cyminum L. is highly adaptable to adversity, but molecular mechanism by which it responds to Pb stress is unknown. For this study, transcriptomic and metabolomic sequencing was performed on root tissues of C. cyminum under Pb stress. Our results showed that high Pb stress increased the activity of peroxidase (POD), the contents of malondialdehyde (MDA) and proline by 80.03 %, 174.46 % and 71.24 %, respectively. Meanwhile, Pb stress decreased the activities of superoxide dismutase (SOD) and catalase (CAT) as well as contents of soluble sugars and GSH, which thus affected the growth of C. cyminum. In addition, Pb stress influenced the accumulation and transport of Pb in C. cyminum. Metabolomic results showed that Pb stress affected eight metabolic pathways involving 108 differentially expressed metabolites, primarily amino acids, organic acids, and carbohydrates. The differentially expressed genes identified through transcriptome analysis were mainly involved the oxidation reductase activity, transmembrane transport, phytohormone signaling, and MAPK signaling pathway. The results of this study will help to understand the molecular mechanisms of C. cyminum response to Pb stress, and provide a basis for screening seeds with strong resistance to heavy metals.
    MeSH term(s) Antioxidants/metabolism ; Cuminum/chemistry ; Cuminum/metabolism ; Lead/toxicity ; Metabolomics ; Gene Expression Profiling
    Chemical Substances Antioxidants ; Lead (2P299V784P)
    Language English
    Publishing date 2024-03-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.171497
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Consistent abnormal activity in the putamen by dopamine modulation in Parkinson's disease: A resting-state neuroimaging meta-analysis.

    Rong, Danyan / Hu, Chuan-Peng / Yang, Jiaying / Guo, Zhiying / Liu, Weiguo / Yu, Miao

    Brain research bulletin

    2024  Volume 210, Page(s) 110933

    Abstract: Objective: This study aimed to elucidate brain areas mediated by oral anti-parkinsonian medicine that consistently show abnormal resting-state activation in PD and to reveal their functional connectivity profiles using meta-analytic approaches.: ... ...

    Abstract Objective: This study aimed to elucidate brain areas mediated by oral anti-parkinsonian medicine that consistently show abnormal resting-state activation in PD and to reveal their functional connectivity profiles using meta-analytic approaches.
    Methods: Searches of the PubMed, Web of Science databases identified 78 neuroimaging studies including PD OFF state (PD-OFF) versus (vs.) PD ON state (PD-ON) or PD-ON versus healthy controls (HCs) or PD-OFF versus HCs data. Coordinate-based meta-analysis and functional meta-analytic connectivity modeling (MACM) were performed using the activation likelihood estimation algorithm.
    Results: Brain activation in PD-OFF vs. PD-ON was significantly changed in the right putamen and left inferior parietal lobule (IPL). Contrast analysis indicated that PD-OFF vs. HCs had more consistent activation in the right paracentral lobule, right middle frontal gyrus, right thalamus, left superior parietal lobule and right putamen, whereas PD-ON vs. HCs elicited more consistent activation in the bilateral middle temporal gyrus, left occipital gyrus, right inferior frontal gyrus and right caudate. MACM revealed coactivation of the right putamen in the direct contrast of PD-OFF vs. PD-ON. Subtraction analysis of significant coactivation clusters for PD-OFF vs. PD-ON with the medium of HCs showed effects in the sensorimotor, top-down control, and visual networks. By overlapping the MACM maps of the two analytical strategies, we demonstrated that the coactivated brain region focused on the right putamen.
    Conclusions: The convergence of local brain regions and co-activation neural networks are involved the putamen, suggesting its potential as a specific imaging biomarker to monitor treatment efficacy.
    Systematic review registration: [https://www.crd.york.ac.uk/PROSPERO/], identifier [CRD CRD42022304150].
    MeSH term(s) Humans ; Parkinson Disease/diagnostic imaging ; Parkinson Disease/drug therapy ; Putamen/diagnostic imaging ; Dopamine ; Magnetic Resonance Imaging/methods ; Brain/diagnostic imaging ; Neuroimaging
    Chemical Substances Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Meta-Analysis ; Journal Article ; Review
    ZDB-ID 197620-5
    ISSN 1873-2747 ; 0361-9230
    ISSN (online) 1873-2747
    ISSN 0361-9230
    DOI 10.1016/j.brainresbull.2024.110933
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: SAC Model Based Improved Genetic Algorithm for Solving TSP

    CHEN Bin, LIU Weiguo

    Jisuanji kexue yu tansuo, Vol 15, Iss 9, Pp 1680-

    2021  Volume 1693

    Abstract: Genetic algorithm (GA) has strong global searching ability and is easy to operate, but its disadvantages such as poor convergence speed, unstable and easy to fall into local optimal value restrict its application. In order to overcome these disadvantages, ...

    Abstract Genetic algorithm (GA) has strong global searching ability and is easy to operate, but its disadvantages such as poor convergence speed, unstable and easy to fall into local optimal value restrict its application. In order to overcome these disadvantages, an improved genetic algorithm based on the deep reinforcement learning model SAC (soft actor-critic) is proposed in this paper, which is applied to the resolution of traveling salesman problem (TSP). The improved algorithm regards the population as agent's interaction environment, meanwhile greedy algorithm is used to initialize this environment for improving the quality of initial populations. For controlling the evolution of the population, the improved crossover and mutation operations are used as agent's action space. With the goal of maximizing the cumulative rewards of population evolution, the improved algorithm treats the evolution of the population as a whole and uses a policy gradient algorithm based on SAC to generate evolution controlling action strategy combined with the current individual fitness of the population. The action strategy reasonably uses the global and local search ability of genetic algorithm by agent's actions, optimizing the evolutionary process of the population while balancing relationship between the population convergence rate and the times of genetic operation. The experimental results of TSPLIB indicate that the improved genetic algorithm can effectively avoid falling into the local optimal solution and reduce the number of iteration in the optimization process while improving the convergence rate of the population.
    Keywords reinforcement learning ; genetic algorithm (ga) ; traveling salesman problem (tsp) ; deep policy gradient ; soft actor-critic (sac) model ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 629
    Language Chinese
    Publishing date 2021-09-01T00:00:00Z
    Publisher Journal of Computer Engineering and Applications Beijing Co., Ltd., Science Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Correction: YOLO POD: a fast and accurate multi-task model for dense Soybean Pod counting.

    Xiang, Shuai / Wang, Siyu / Xu, Mei / Wang, Wenyan / Liu, Weiguo

    Plant methods

    2023  Volume 19, Issue 1, Page(s) 45

    Language English
    Publishing date 2023-05-12
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2203723-8
    ISSN 1746-4811
    ISSN 1746-4811
    DOI 10.1186/s13007-023-01013-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Quantum transport simulations of sub-5 nm bilayer Ga

    Li, Penghui / Dong, Linpeng / Peng, Bo / Nan, Kai / Liu, Weiguo

    Journal of physics. Condensed matter : an Institute of Physics journal

    2023  Volume 36, Issue 3

    Abstract: Two-dimensional (2D) semiconductors with bizarre properties show great application potential for nanoscale devices, which is regarded as the Si alternation to extend the Moore's Law in sub-5 nm era. In this study, we investigate the electronic structure ... ...

    Abstract Two-dimensional (2D) semiconductors with bizarre properties show great application potential for nanoscale devices, which is regarded as the Si alternation to extend the Moore's Law in sub-5 nm era. In this study, we investigate the electronic structure and ballistic transport characteristics of sub-5 nm bilayer (BL) Ga
    Language English
    Publishing date 2023-10-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472968-4
    ISSN 1361-648X ; 0953-8984
    ISSN (online) 1361-648X
    ISSN 0953-8984
    DOI 10.1088/1361-648X/ad00f5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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