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  1. Article ; Online: Research on Pedestrian Detection Model and Compression Technology for UAV Images.

    Liu, Xihao / Wang, Chengbo / Liu, Li

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 23

    Abstract: The large view angle and complex background of UAV images bring many difficulties to the detection of small pedestrian targets in images, which are easy to be detected incorrectly or missed. In addition, the object detection models based on deep learning ...

    Abstract The large view angle and complex background of UAV images bring many difficulties to the detection of small pedestrian targets in images, which are easy to be detected incorrectly or missed. In addition, the object detection models based on deep learning are usually complex and the high computational resource consumption limits the application scenarios. For small pedestrian detection in UAV images, this paper proposes an improved YOLOv5 method to improve the detection ability of pedestrians by introducing a new small object feature detection layer in the feature fusion layer, and experiments show that the improved method can improve the average precision by 4.4%, which effectively improves the pedestrian detection effect. To address the problem of high computational resource consumption, the model is compressed using channel pruning technology to reduce the consumption of video memory and computing power in the inference process. Experiments show that the model can be compressed to 11.2 MB and the GFLOPs of the model are reduced by 11.9% compared with that before compression under the condition of constant inference accuracy, which is significant for the deployment and application of the model.
    Language English
    Publishing date 2022-11-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22239171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Operando spectroscopies capturing surface reconstruction and interfacial electronic regulation by FeOOH@Fe

    Tang, Mei / Liu, Xihao / Ali, Asad / He, Youme / Shen, Peikang / Ouyang, Yifang

    Journal of colloid and interface science

    2023  Volume 636, Page(s) 501–511

    Abstract: Developing high-performance and low-cost electrocatalysts for oxygen evolution reaction (OER) and understanding the phase evolution in the catalytic process are vital to improving the overall efficiency of electrochemical water splitting. Herein, a ... ...

    Abstract Developing high-performance and low-cost electrocatalysts for oxygen evolution reaction (OER) and understanding the phase evolution in the catalytic process are vital to improving the overall efficiency of electrochemical water splitting. Herein, a hybrid heterogeneous FeOOH@Fe
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2023.01.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Cao-Xiang-Wei-Kang formula attenuates the progression of experimental colitis by restoring the homeostasis of the microbiome and suppressing inflammation.

    Yu, Wei / Li, Qi / Shao, Changlei / Zhang, Yijia / Kang, Cai / Zheng, Yang / Liu, Xihao / Liu, Xincheng / Yan, Jing

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 946065

    Abstract: Inflammatory bowel disease (IBD) is pathologically characterized by an immune response accommodative insufficiency and dysbiosis accompanied by persistent epithelial barrier dysfunction. The Cao-Xiang-Wei-Kang (CW) formula has been utilized to treat ... ...

    Abstract Inflammatory bowel disease (IBD) is pathologically characterized by an immune response accommodative insufficiency and dysbiosis accompanied by persistent epithelial barrier dysfunction. The Cao-Xiang-Wei-Kang (CW) formula has been utilized to treat gastrointestinal disorders in the clinic. The present study was designed to delineate the pharmacological mechanisms of this formula from different aspects of the etiology of ulcerative colitis (UC), a major subtype of IBD. Dextran sodium sulfate (DSS) was given to mice for a week at a concentration of 2%, and the CW solution was administered for 3 weeks. 16S rRNA gene sequencing and untargeted metabolomics were conducted to examine the changes in the microbiome profile, and biochemical experiments were performed to confirm the therapeutic functions predicted by system pharmacology analysis. The CW treatment hampered DSS-induced experimental colitis progression, and the targets were enriched in inflammation, infection, and tumorigenesis, which was corroborated by suppressed caspase 3 (Casp3) and interleukin-1b (IL-1b) and increased cleaved caspase 3 expression and casp-3 activity in the colon samples from colitis mice subjected to the CW therapy. Moreover, the CW therapy rescued the decreased richness and diversity, suppressed the potentially pathogenic phenotype of the gut microorganisms, and reversed the altered linoleic acid metabolism and cytochrome P450 activity in murine colitis models. In our
    Language English
    Publishing date 2022-09-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.946065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Validation of the Anticolitis Efficacy of the Jian-Wei-Yu-Yang Formula.

    Yan, Jing / Tang, Yan / Yu, Wei / Jiang, Lu / Liu, Chen / Li, Qi / Zhang, Zhiqiang / Shao, Changlei / Zheng, Yang / Liu, Xihao / Liu, Xincheng

    Evidence-based complementary and alternative medicine : eCAM

    2022  Volume 2022, Page(s) 9110704

    Abstract: Background: Inflammatory bowel disease (IBD) is a major cause of morbidity and mortality due to its repetitive remission and relapse. The Jian-Wei-Yu-Yang (JW) formula has a historical application in the clinic to combat gastrointestinal disorders. The ... ...

    Abstract Background: Inflammatory bowel disease (IBD) is a major cause of morbidity and mortality due to its repetitive remission and relapse. The Jian-Wei-Yu-Yang (JW) formula has a historical application in the clinic to combat gastrointestinal disorders. The investigation aimed to explore the molecular and cellular mechanisms of JW.
    Methods: 2% dextran sodium sulfate (DSS) was diluted in drinking water and given to mice for 5 days to establish murine models of experimental colitis, and different doses of JW solution were administered for 14 days. Network pharmacology analysis and weighted gene co-expression network analysis (WGCNA) were utilized to predict the therapeutic role of JW against experimental colitis and colitis-associated colorectal cancer (CAC). 16S rRNA sequencing and untargeted metabolomics were conducted using murine feces. Western blotting, immunocytochemistry, and wound healing experiments were performed to confirm the molecular mechanisms.
    Results: (1) Liquid chromatography with mass spectrometry was utilized to confirm the validity of the JW formula. The high dose of JW treatment markedly attenuated DSS-induced experimental colitis progression, and the targets were enriched in inflammation, infection, and tumorigenesis. (2) The JW targets were related to the survival probability in patients with colorectal cancer, underlying a potential therapeutic value in CRC intervention. (3) Moreover, the JW therapy successfully rescued the decreased richness and diversity of microbiota, suppressed the potentially pathogenic phenotype of the gut microorganisms, and increased cytochrome P450 activity in murine colitis models. (4) Our
    Conclusion: The JW capsule attenuated the progression of murine colitis by a prompt resolution of inflammation and bloody stool and by re-establishing a microbiome profile that favors re-epithelization and prevents carcinogenesis.
    Language English
    Publishing date 2022-08-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2022/9110704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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