LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Zurück zur letzten Suche Suchhistorie
Erweiterte Suche

Ihre letzten Suchen

  1. AU="Liu, Xingzheng"
  2. AU="Głód, Mateusz"
  3. AU=Teo Kelvin Yi Chong
  4. AU="Khatmi, Aysan"
  5. AU="Erculiani, M"
  6. AU="Olivier Lortholary"
  7. AU="Lisnic, Vanda Juranic"
  8. AU="Seabloom, Eric W"
  9. AU="Odvina, Clarita V"
  10. AU="Singh, Inderbir"
  11. AU="Wonoh Lee"
  12. AU="Nelson, Warrick"
  13. AU="Douglas, David N"
  14. AU="King, Gary"
  15. AU="Barbera, Lauren"
  16. AU="Carlino, Antonio"
  17. AU="Shan, Qing-Hua"
  18. AU="Starko, S"
  19. AU="Lievre, Loïc"
  20. AU=Cammack N
  21. AU="Xia, Qin"
  22. AU="Ong, Ju Lynn"
  23. AU="Cullin, Christophe"
  24. AU="Georg K.S. Andersson"
  25. AU="Jeannel, Gaël-François"
  26. AU="Stuart Woods"
  27. AU="Shchegolev, A."
  28. AU="Nadeau, Pierre-Louis"
  29. AU="Gordon, David E A"
  30. AU="Shahid Mahmood"
  31. AU="Rosenblatt, Karin"
  32. AU="Dasgupta, Suvankar"
  33. AU=Nguyen Sylvain AU=Nguyen Sylvain

Suchergebnis

Treffer 1 - 8 von insgesamt 8

Suchoptionen

  1. Artikel: Causal relationship between gut microbiota and chronic renal failure: a two-sample Mendelian randomization study.

    Liu, Xingzheng / Mo, Jinying / Yang, Xuerui / Peng, Ling / Zeng, Youjia / Zheng, Yihou / Song, Gaofeng

    Frontiers in microbiology

    2024  Band 15, Seite(n) 1356478

    Abstract: Background: Observational studies and some experimental investigations have indicated that gut microbiota are closely associated with the incidence and progression of chronic renal failure. However, the causal relationship between gut microbiota and ... ...

    Abstract Background: Observational studies and some experimental investigations have indicated that gut microbiota are closely associated with the incidence and progression of chronic renal failure. However, the causal relationship between gut microbiota and chronic renal failure remains unclear. The present study employs a two-sample Mendelian randomization approach to infer the causal relationship between gut microbiota and chronic renal failure at the genetic level. This research aims to determine whether there is a causal effect of gut microbiota on the risk of chronic renal failure, aiming to provide new evidence to support targeted gut therapy for the treatment of chronic renal failure.
    Methods: Employing genome-wide association study (GWAS) data from the public MiBioGen and IEU OpenGWAS platform, a two-sample Mendelian randomization analysis was conducted. The causal relationship between gut microbiota and chronic renal failure was inferred using five different methods: Inverse Variance Weighted, MR-Egger, Weighted Median, Simple Mode, and Weighted Mode. The study incorporated sensitivity analyses that encompassed evaluations for pleiotropy and heterogeneity. Subsequently, the results of the Mendelian randomization analysis underwent a stringent correction for multiple testing, employing the False Discovery Rate method to enhance the validity of our findings.
    Results: According to the results from the Inverse Variance Weighted method, seven bacterial genera show a significant association with the outcome variable chronic renal failure. Of these, Ruminococcus (gauvreauii group) (OR = 0.82, 95% CI = 0.71-0.94,
    Conclusion: Our two-sample Mendelian randomization study suggests that the genera Escherichia-Shigella and Howardella are risk factors for chronic renal failure, and they may serve as potential targets for future therapeutic interventions. However, the exact mechanisms of action are not yet clear, necessitating further research to elucidate their precise roles fully.
    Sprache Englisch
    Erscheinungsdatum 2024-04-03
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2024.1356478
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  2. Artikel ; Online: Circulating galectin-3 level association with cardiovascular risk factors during peritoneal dialysis.

    Yang, Xuerui / Yang, Jun / Zeng, Youjia / Peng, Ling / Liu, Xingzheng / Mo, Jinying / Wang, Taifen / Yao, Yutong / Zheng, Yihou / Song, Gaofeng

    Clinical and experimental nephrology

    2024  

    Abstract: Objective: Cardiovascular disease (CVD) represents the primary cause of mortality in patients afflicted with end-stage renal disease and undergoing peritoneal dialysis (PD) treatment. Galectin-3 (Gal-3), a molecule known to exhibit a correlation with ... ...

    Abstract Objective: Cardiovascular disease (CVD) represents the primary cause of mortality in patients afflicted with end-stage renal disease and undergoing peritoneal dialysis (PD) treatment. Galectin-3 (Gal-3), a molecule known to exhibit a correlation with CVD mortality garners considerable interest. The objective of this study was to explore the potential association between serum Gal-3 levels and other CVD risk factors among PD patients.
    Methods: In this cross-sectional study, a total of 114 PD patients with a minimum of 3 months of PD treatment were enrolled. Serum Gal-3 levels were quantified using an enzyme-linked immunosorbent assay. The data of patients with Gal-3 levels higher and lower than 26.744 pg/ml were compared using Mann-Whitney U tests or t tests. Pearson's correlation or Spearman's correlation analysis and multivariate regression were used to assess the associations between the known risk factors for CVD and Gal-3.
    Results: In comparison to the inter-group baseline data, the low Gal-3 group exhibited a higher glomerular filtration rate (GFR). Gal-3 levels correlate positively with PD duration, B-type natriuretic peptide (BNP), growth differentiation factor 15 (GDF-15), interventricular septal thickness in diastolic (IVST), and left ventricular mass index (LVMI). Conversely, Gal-3 exhibited a negative correlation with albumin levels. Multivariate linear regression analysis demonstrated a positive correlation between Gal-3 levels and BNP, GDF-15, PD duration, IVST and LVMI. Gal-3 levels were negatively correlated with albumin levels.
    Conclusions: Gal-3 was strongly associated with BNP, GDF-15, IVST and LVMI in patients undergoing PD treatment. Prospective studies should be carried out to determine whether Gal-3 can be a promising biomarker in predicting increased risk of adverse cardiovascular events in PD patients.
    Sprache Englisch
    Erscheinungsdatum 2024-04-20
    Erscheinungsland Japan
    Dokumenttyp Journal Article
    ZDB-ID 1338768-6
    ISSN 1437-7799 ; 1342-1751
    ISSN (online) 1437-7799
    ISSN 1342-1751
    DOI 10.1007/s10157-024-02498-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 4922: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  3. Artikel ; Online: A New Noncovalently Fused-Ring Electron Acceptor Based on 3,7-Dialkyloxybenzo[1,2-b:4,5-b']dithiophene for Low-Cost and High-Performance Organic Solar Cells.

    Zhang, Xin / Qin, Linqing / Li, Laiyang / Liu, Xingzheng / Wei, Yanan / Huang, Hui

    Macromolecular rapid communications

    2022  Band 43, Heft 16, Seite(n) e2200085

    Abstract: The innovation of high-performance fused-ring electron acceptors (FREAs) has carried the field of organic solar cells (OSCs) toward a new stage of development. However, due to high synthetic complexity and production costs, FREAs may not be the most ... ...

    Abstract The innovation of high-performance fused-ring electron acceptors (FREAs) has carried the field of organic solar cells (OSCs) toward a new stage of development. However, due to high synthetic complexity and production costs, FREAs may not be the most promising candidates for future commercialization applications. To address these disadvantages of FREAs, a series of low-cost acceptors, named as noncovalently FREAs (NFREAs), is successfully constructed by employing the strategy of noncovalently conformational locks. Herein, a novel NFREA (BDTO-4F) based on 3,7-dialkyloxybenzo[1,2-b:4,5-b']dithiophene is synthesized and fully characterized. Benefiting from the complementary absorption of the donor and acceptor, balanced charge transport, and favorable film morphology, J52:BDTO-4F based OSCs afford a satisfied power conversion efficiency of 12.09%, much higher than PBDB-T:BDTO-4F-based devices (8.30%). It is worth mentioning that BDTO-4F possesses a higher figure-of-merit value of 55.65 in comparison with several representative FREAs based on a cost-efficiency evaluation. This work demonstrates the potential of the novel benzo[1,2-b:4,5-b″]dithiophene derivative for constructing low-cost and high-performance NFREAs, providing a valuable insight on the materials design.
    Sprache Englisch
    Erscheinungsdatum 2022-04-01
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 1475027-2
    ISSN 1521-3927 ; 1022-1336
    ISSN (online) 1521-3927
    ISSN 1022-1336
    DOI 10.1002/marc.202200085
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  4. Artikel: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly(l-Glutamic Acid)-Poly(l-Phenylalanine) Triblock Polymer for Sustained Drug Delivery.

    Liu, Xingzheng / Fan, Rongrong / Lu, Boting / Le, Yuan

    Pharmaceutics

    2018  Band 10, Heft 4

    Abstract: Methoxy-poly(ethylene glycol)-poly(l-glutamic acid)-poly(l-phenylalanine) triblock polymers with different architecture were synthesized as drug carrier to obtain sustained and controlled release by tuning the composition. These triblock polymers were ... ...

    Abstract Methoxy-poly(ethylene glycol)-poly(l-glutamic acid)-poly(l-phenylalanine) triblock polymers with different architecture were synthesized as drug carrier to obtain sustained and controlled release by tuning the composition. These triblock polymers were prepared by ring opening polymerization and poly(ethylene glycol) was used as an initiator. Polymerization was confirmed by ¹H NMR, FT-IR and gel penetration chromatography. The polymers can self-assemble to form micelles in aqueous medium and their critical micelle concentrations values were examined. The micelles were spherical shape with size of 50⁻100 nm and especially can arranged in a regular manner. Sorafenib was selected as the model drug and the drug loading performance was dependent on the composition of the block copolymer. In vitro drug release indicated that the polymers can realize controlled and sustained drug release. Furthermore, in vitro cytotoxicity assay showed that the polymers were biocompatible and the drug-loaded micelles can increase toxicity towards tumor cells. Confocal fluorescence microscopy assays illustrated that the micelles can be uptaken quickly and release drug persistently to inhibit tumor cell growth.
    Sprache Englisch
    Erscheinungsdatum 2018-11-13
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics10040230
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  5. Artikel ; Online: High-Performance Noncovalently Fused-Ring Electron Acceptors for Organic Solar Cells Enabled by Noncovalent Intramolecular Interactions and End-Group Engineering.

    Zhang, Xin / Qin, Linqing / Yu, Jianwei / Li, Yuhao / Wei, Yanan / Liu, Xingzheng / Lu, Xinhui / Gao, Feng / Huang, Hui

    Angewandte Chemie (International ed. in English)

    2021  Band 60, Heft 22, Seite(n) 12475–12481

    Abstract: Noncovalently fused-ring electron acceptors (NFREAs) have attracted much attention in recent years owing to their advantages of simple synthetic routes, high yields and low costs. However, the efficiencies of NFREAs based organic solar cells (OSCs) are ... ...

    Abstract Noncovalently fused-ring electron acceptors (NFREAs) have attracted much attention in recent years owing to their advantages of simple synthetic routes, high yields and low costs. However, the efficiencies of NFREAs based organic solar cells (OSCs) are still far behind those of fused-ring electron acceptors (FREAs). Herein, a series of NFREAs with S⋅⋅⋅O noncovalent intramolecular interactions were designed and synthesized with a two-step synthetic route. Upon introducing π-extended end-groups into the backbones, the electronic properties, charge transport, film morphology, and energy loss were precisely tuned by fine-tuning the degree of multi-fluorination. As a result, a record PCE of 14.53 % in labs and a certified PCE of 13.8 % for NFREAs based devices were obtained. This contribution demonstrated that combining the strategies of noncovalent conformational locks and π-extended end-group engineering is a simple and effective way to explore high-performance NFREAs.
    Sprache Englisch
    Erscheinungsdatum 2021-04-20
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202100390
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  6. Artikel ; Online: Conductive Skeleton-Heterostructure Composites Based on Chrome Shavings for Enhanced Electromagnetic Interference Shielding.

    Zhang, Jian / Yan, Zixuan / Liu, Xingzheng / Zhang, Yu / Zou, Haikui / Le, Yuan / Chen, Jian-Feng

    ACS applied materials & interfaces

    2020  Band 12, Heft 47, Seite(n) 53076–53087

    Abstract: Renewable bio-based electromagnetic interference (EMI) shielding materials receive increasing attention undoubtedly. However, there is still a challenge to use raw biomass materials to construct a significant structure through an effortless and ... ...

    Abstract Renewable bio-based electromagnetic interference (EMI) shielding materials receive increasing attention undoubtedly. However, there is still a challenge to use raw biomass materials to construct a significant structure through an effortless and environmental route for EMI shielding applications. Herein, for the first time, we demonstrated a hybrid composite of multi-walled carbon nanotube/polypyrrole/chrome-tanned collagen fiber (MWCNT/PPy/CF), which utilized waste chrome shavings as a matrix. X-ray photoelectron spectroscopy reveals that the chromium on the CF has a binding effect on the PPy layer, which endows the tight integration between the CF and PPy layer. After the MWCNT network was loaded on the PPy layer, this ternary structure could provide stable conductive paths and a rich number of polarized interfaces. The MWCNT/PPy/CF composite exhibits superior electrical conductivity (354 ± 52 S/m), higher than PPy/CF (222 ± 38 S/m) and MWCNT/CF (104 ± 11 S/m), owing to the synergy of dual conductive structures. Notably, the shielding effectiveness (SE) value of the MWCNT/PPy/CF composite reaches 30 dB in the X band at a thickness of 0.48 mm. The shielding effectiveness of reflection (SE
    Sprache Englisch
    Erscheinungsdatum 2020-11-10
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.0c14300
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  7. Artikel ; Online: Side-Chain Engineering for Enhancing the Molecular Rigidity and Photovoltaic Performance of Noncovalently Fused-Ring Electron Acceptors.

    Zhang, Xin / Li, Congqi / Qin, Linqing / Chen, Hao / Yu, Jianwei / Wei, Yanan / Liu, Xingzheng / Zhang, Jianqi / Wei, Zhixiang / Gao, Feng / Peng, Qian / Huang, Hui

    Angewandte Chemie (International ed. in English)

    2021  Band 60, Heft 32, Seite(n) 17720–17725

    Abstract: Side-chain engineering is an effective strategy to regulate the solubility and packing behavior of organic materials. Recently, a unique strategy, so-called terminal side-chain (T-SC) engineering, has attracted much attention in the field of organic ... ...

    Abstract Side-chain engineering is an effective strategy to regulate the solubility and packing behavior of organic materials. Recently, a unique strategy, so-called terminal side-chain (T-SC) engineering, has attracted much attention in the field of organic solar cells (OSCs), but there is a lack of deep understanding of the mechanism. Herein, a new noncovalently fused-ring electron acceptor (NFREA) containing two T-SCs (NoCA-5) was designed and synthesized. Introduction of T-SCs can enhance molecular rigidity and intermolecular π-π stacking, which is confirmed by the smaller Stokes shift value, lower reorganization free energy, and shorter π-π stacking distance in comparison to NoCA-1. Hence, the NoCA-5-based device exhibits a record power conversion efficiency (PCE) of 14.82 % in labs and a certified PCE of 14.5 %, resulting from a high electron mobility, a short charge-extraction time, a small Urbach energy (E
    Sprache Englisch
    Erscheinungsdatum 2021-06-30
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202106753
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  8. Artikel ; Online: Triplet Acceptors with a D-A Structure and Twisted Conformation for Efficient Organic Solar Cells.

    Qin, Linqing / Liu, Xingzheng / Zhang, Xin / Yu, Jianwei / Yang, Lei / Zhao, Fenggui / Huang, Miaofei / Wang, Kangwei / Wu, Xiaoxi / Li, Yuhao / Chen, Hao / Wang, Kai / Xia, Jianlong / Lu, Xinhui / Gao, Feng / Yi, Yuanping / Huang, Hui

    Angewandte Chemie (International ed. in English)

    2020  Band 59, Heft 35, Seite(n) 15043–15049

    Abstract: Triplet acceptors have been developed to construct high-performance organic solar cells (OSCs) as the long lifetime and diffusion range of triplet excitons may dissociate into free charges instead of net recombination when the energy levels of the lowest ...

    Abstract Triplet acceptors have been developed to construct high-performance organic solar cells (OSCs) as the long lifetime and diffusion range of triplet excitons may dissociate into free charges instead of net recombination when the energy levels of the lowest triplet state (T
    Sprache Englisch
    Erscheinungsdatum 2020-06-09
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202006081
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

Zum Seitenanfang