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  1. Article: [Advances in the etiology of retroperitoneal liposarcoma].

    Yuan, Z Q / Liu, Y B

    Zhonghua wai ke za zhi [Chinese journal of surgery

    2024  Volume 62, Issue 5, Page(s) 473–477

    Abstract: Retroperitoneal liposarcoma is the most common retroperitoneal soft tissue tumor with insidious onset, difficulty in treatment, and easy recurrence. Different subtypes of retroperitoneal liposarcoma differ significantly in pathogenic mechanism, ... ...

    Abstract Retroperitoneal liposarcoma is the most common retroperitoneal soft tissue tumor with insidious onset, difficulty in treatment, and easy recurrence. Different subtypes of retroperitoneal liposarcoma differ significantly in pathogenic mechanism, biological behavior, and prognosis. The characteristic molecular event of well-differentiated and dedifferentiated liposarcoma is the amplification of the long arm segment of chromosome 12. The genome of myxoid liposarcoma is characterized by translocations of chromosomes 12 and 16 to form fusion genes. The genomic changes of pleomorphic and myxoid pleomorphic liposarcoma are complex, with multiple chromosomal structural abnormalities. Several signaling pathways related to adipocyte differentiation or lipid metabolism have been found to be involved in the initiation and progression of retroperitoneal liposarcoma. It is unclear whether retroperitoneal liposarcoma originates from naive preadipocytes or dedifferentiated mature adipocytes, and its metabolic characteristics are also poorly understood. The first-line drug treatment for retroperitoneal liposarcoma is anthracycline-based chemotherapy, but patients receive little benefit. Therefore, it is urgent to strengthen the basic research on retroperitoneal liposarcoma to find effective therapeutic targets.
    Language Chinese
    Publishing date 2024-03-27
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 604573-x
    ISSN 0529-5815
    ISSN 0529-5815
    DOI 10.3760/cma.j.cn112139-20231018-00179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Progress of radical resection of pancreatic cancer].

    Jia, Z H / Liu, Y B

    Zhonghua wai ke za zhi [Chinese journal of surgery

    2023  Volume 61, Issue 4, Page(s) 344–348

    Abstract: Pancreatic cancer is a malignant disease with an extremely poor prognosis. For now, radical resection is the only long-term survival approach. Therefore, for complete resection of different types of pancreatic neoplasms, scholars and surgeons have ... ...

    Abstract Pancreatic cancer is a malignant disease with an extremely poor prognosis. For now, radical resection is the only long-term survival approach. Therefore, for complete resection of different types of pancreatic neoplasms, scholars and surgeons have innovated and applied numerous surgical methods. Aiming at various situations, a large amout of methods and principles have been suggested. Unresectable neoplasms have been challenged day by day. Meanwhile, with the progression of technology, minimally invasive techniques have been applied to resection of pancreatic neoplasms. This article mainly reviews the innovation of surgical methods and technology in radical surgery of pancreatic cancer in recent years.
    MeSH term(s) Humans ; Pancreatic Neoplasms/surgery ; Pancreatic Neoplasms/pathology ; Prognosis ; Pancreatectomy/methods ; Pancreatic Neoplasms
    Language Chinese
    Publishing date 2023-03-21
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 604573-x
    ISSN 0529-5815
    ISSN 0529-5815
    DOI 10.3760/cma.j.cn112139-20220608-00259
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Attach importance to the standardized diagnosis and treatment of gallbladder carcinoma].

    Liu, Y B / Chen, W

    Zhonghua wai ke za zhi [Chinese journal of surgery

    2021  Volume 59, Issue 4, Page(s) 249–254

    Abstract: Gallbladder carcinoma,characterized by concealed onset,rapid development,and poor prognosis,needs to be valued by clinicians.The key to improving its prognosis remains early diagnosis and standardized therapy.Improving the sensitivity and accuracy of ... ...

    Abstract Gallbladder carcinoma,characterized by concealed onset,rapid development,and poor prognosis,needs to be valued by clinicians.The key to improving its prognosis remains early diagnosis and standardized therapy.Improving the sensitivity and accuracy of hematological and imaging diagnosis and early detection of specific molecular diagnostic targets for gallbladder cancer are helpful for early diagnosis and treatment.It is of great importance to emphasize on intraoperative reassessment and select the correct surgical procedures.It is the primary condition for increasing the R0 radical resection rate and improving the prognosis that prudentially carrying out laparoscopic radical resection and referring to standardized resection of cancer foci and regional lymph node removal.In the future,guided by concepts of oncology,comprehensive treatment of multiple modes,containing surgery,chemotherapy,targeted,immune and biological therapy,is the development trend of gallbladder cancer treatment,which requires high-quality clinical research and interdisciplinary cooperation.
    Language Chinese
    Publishing date 2021-04-01
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 604573-x
    ISSN 0529-5815
    ISSN 0529-5815
    DOI 10.3760/cma.j.cn112139-20210115-00031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Clinical effect of anterolateral thigh flow-through chimeric perforator free flap transplantation in the treatment of upper limb complex tissue defects with main artery injury].

    Liu, F / Yan, W Q / Ma, Q / Liu, Y B / Yang, Z B

    Zhonghua shao shang yu chuang mian xiu fu za zhi

    2024  Volume 40, Issue 2, Page(s) 172–179

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Female ; Humans ; Male ; Brachial Artery/surgery ; Free Tissue Flaps/surgery ; Plastic Surgery Procedures ; Skin Transplantation ; Soft Tissue Injuries/surgery ; Thigh/surgery ; Treatment Outcome ; Upper Extremity/surgery ; Retrospective Studies
    Language Chinese
    Publishing date 2024-02-28
    Publishing country China
    Document type Observational Study ; English Abstract ; Journal Article
    ISSN 2097-1109
    ISSN 2097-1109
    DOI 10.3760/cma.j.cn501225-20231103-00176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Progress in omics research and preclinical models of gallbladder cancer].

    Yang, M J / Wu, Y / Xiang, D X / Liu, Y B

    Zhonghua wai ke za zhi [Chinese journal of surgery

    2023  Volume 61, Issue 3, Page(s) 260–264

    Abstract: Gallbladder cancer(GBC)is one common type of bile tract cancers with poor prognosis. This review summarizes the recent development of studies about somatic mutation, molecular subtype, microenvironment heterogeneity, organoid, orthotopic model, patient- ... ...

    Abstract Gallbladder cancer(GBC)is one common type of bile tract cancers with poor prognosis. This review summarizes the recent development of studies about somatic mutation, molecular subtype, microenvironment heterogeneity, organoid, orthotopic model, patient-derived xenograft and clinical translation on GBC in aspects of genomic,transcriptome,single cell omics and clinical translation. We expect this review will provide new ideas on dissecting molecular mechanisms underlying the development and emerging chemoresistance of GBC following therapy and promote GBC precision medicine.
    MeSH term(s) Humans ; Gallbladder Neoplasms/genetics ; Prognosis ; Tumor Microenvironment
    Language Chinese
    Publishing date 2023-01-19
    Publishing country China
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 604573-x
    ISSN 0529-5815
    ISSN 0529-5815
    DOI 10.3760/cma.j.cn112139-20220430-00193
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Progress of genomic mutation spectrum in biliary tract malignant tumors].

    Qiu, S M / Liu, F T / Wu, W W / Liu, Y B

    Zhonghua wai ke za zhi [Chinese journal of surgery

    2023  Volume 61, Issue 12, Page(s) 1124–1129

    Abstract: Biliary tract cancer is characterized by high invasiveness, occult early clinical manifestations and rapid progression. Surgical resection typically fails to achieve satisfactory outcomes. Biliary tract cancer exhibits low sensitivity to radiotherapy and ...

    Abstract Biliary tract cancer is characterized by high invasiveness, occult early clinical manifestations and rapid progression. Surgical resection typically fails to achieve satisfactory outcomes. Biliary tract cancer exhibits low sensitivity to radiotherapy and chemotherapy. The prognosis of patients is extremely poor. Genomics research based on next-generation sequencing technology has made some advances. The gene mutation spectrum of biliary tract cancer has been preliminarily revealed, which lays a foundation for the study of molecular typing. This review summarizes the research progress and clinical application of gene mutation spectrum of biliary tract cancer in recent years, aiming to provide reference for the clinical diagnosis, treatment and basic research.
    MeSH term(s) Humans ; Biliary Tract Neoplasms/genetics ; Biliary Tract Neoplasms/therapy ; Prognosis ; Mutation ; Genomics ; Biliary Tract
    Language Chinese
    Publishing date 2023-11-06
    Publishing country China
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 604573-x
    ISSN 0529-5815
    ISSN 0529-5815
    DOI 10.3760/cma.j.cn112139-20230518-00208
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Application and prospect of artificial intelligence in pancreatic cancer].

    Zheng, Z Y / Chen, T / Liu, Y B

    Zhonghua wai ke za zhi [Chinese journal of surgery

    2022  Volume 61, Issue 1, Page(s) 76–80

    Abstract: As a severe malignant tumor of the digestive system,the highly invasive pancreatic cancer lacks typical preliminary symptoms. Rapid metastatic dissemination and difficulty in early-stage diagnosis preclude the chance of radical curative resection,hence ... ...

    Abstract As a severe malignant tumor of the digestive system,the highly invasive pancreatic cancer lacks typical preliminary symptoms. Rapid metastatic dissemination and difficulty in early-stage diagnosis preclude the chance of radical curative resection,hence resulting in a poor overall prognosis in most patients. In recent years,the wide application of the artificial intelligence(AI),represented by machine learning and deep learning,has developed rapidly in the field of medicine. All sorts of models based on AI have been applied to the screening, early diagnosis, treatment, prognosis prediction of patients with pancreatic cancer.Three-dimentional visualization and augmented reality navigation technologies have also been developed and applied in pancreatic cancer surgery.This paper reviews the status quo of AI application in pancreatic cancer from various aspects,and anticipates its future application prospects.
    MeSH term(s) Humans ; Artificial Intelligence ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/surgery ; Pancreas ; Machine Learning ; Pancreatic Neoplasms
    Language Chinese
    Publishing date 2022-12-16
    Publishing country China
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 604573-x
    ISSN 0529-5815
    ISSN 0529-5815
    DOI 10.3760/cma.j.cn112139-20220419-00176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Management of coronavirus disease 2019 (COVID-19): experiences from imported malaria control in China].

    Liu, Y B / Cao, J

    Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control

    2020  Volume 32, Issue 2, Page(s) 113–118

    Abstract: Currently, the local transmission of coronavirus disease 2019 (COVID-19) has been effectively contained in China; however, the epidemic situation of this highly infectious disease is more and more serious outside of China. Importation of COVID-19 cases ... ...

    Abstract Currently, the local transmission of coronavirus disease 2019 (COVID-19) has been effectively contained in China; however, the epidemic situation of this highly infectious disease is more and more serious outside of China. Importation of COVID-19 cases from other countries and territories is therefore becoming a new challenge for the control of COVID-19 in China. Malaria was once widely epidemic in China. Nevertheless, the local transmission of this parasitic disease has been interrupted in China since the launch of the national malaria elimination programme in 2010, and great successes have been achieved in the management of appropriately 3 thousand malaria cases imported from other countries and territories annually. Hereby, the epidemiological characteristics and current epidemic situation of COVID-19 in China were analyzed and compared with malaria. Based on the successful experiences from the management of overseas imported malaria in China, the strategy and countermeasures for COVID-19 control were proposed, so as to provide insights into the response to the importation of COVID-19 from other countries and territories and the consolidation of the control achievements in China.
    MeSH term(s) Betacoronavirus/isolation & purification ; COVID-19 ; China/epidemiology ; Communicable Diseases, Imported/prevention & control ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Disease Eradication/methods ; Humans ; Malaria/prevention & control ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; SARS-CoV-2
    Keywords covid19
    Language Chinese
    Publishing date 2020-05-27
    Publishing country China
    Document type Journal Article
    ISSN 1005-6661
    ISSN 1005-6661
    DOI 10.16250/j.32.1374.2020063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [The impact of the number of previous miscarriages on embryo euploid rate and pregnancy outcomes in patients with unexplained recurrent pregnancy loss].

    Zhao, S T / Liu, Y B / Zhang, Q / Ni, T X / Yan, J H

    Zhonghua yi xue za zhi

    2023  Volume 103, Issue 36, Page(s) 2874–2880

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Pregnancy ; Humans ; Female ; Adult ; Pregnancy Outcome ; Retrospective Studies ; Pregnancy Rate ; Aneuploidy ; Abortion, Habitual
    Language Chinese
    Publishing date 2023-09-20
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20221226-02698
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Analysis of clinical and prognostic characteristics of newly diagnosed multiple myeloma with myelofibrosis patients].

    Zhang, L / Li, Y L / Liu, Y M / Liu, Y B / Shang, B J / Cheng, W / Dong, X Y / Zhu, Z M

    Zhonghua yi xue za zhi

    2024  Volume 104, Issue 1, Page(s) 57–62

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Male ; Female ; Humans ; Prognosis ; Multiple Myeloma/diagnosis ; In Situ Hybridization, Fluorescence ; Primary Myelofibrosis ; Retrospective Studies
    Language Chinese
    Publishing date 2024-01-08
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20230713-00005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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