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  1. Article: Effects of simulated nitrogen deposition on the soil microbial community diversity of a Deyeuxia angustifolia wetland in the Sanjiang Plain, Northeastern China

    Zhang, Rong-Tao / Liu, Ying-Nan / Zhong, Hai-Xiu / Chen, Xiang-Wei / Sui, Xin

    Annals of microbiology. 2022 Dec., v. 72, no. 1

    2022  

    Abstract: PURPOSE: The soil microbial community is an important bioactive component of terrestrial ecosystems. Its structural and functional diversity directly affects carbon and nitrogen processes. This study aimed to investigate the variations in the diversity ... ...

    Abstract PURPOSE: The soil microbial community is an important bioactive component of terrestrial ecosystems. Its structural and functional diversity directly affects carbon and nitrogen processes. This study aimed to investigate the variations in the diversity and composition of soil bacterial communities in a wetland with different nitrogen deposition conditions. METHODS: A long-term simulated nitrogen deposition experiment was conducted in the Ecological Locating Research Station of the Institute of Nature and Ecology of Heilongjiang Academy of Sciences. Three different treatments were evaluated, including low nitrogen (LK; 40 kg N·hm⁻²·a⁻¹), high nitrogen (HN; 80 kg N·hm⁻²·a⁻¹), and control (CK; 0 kg N·hm⁻²·a⁻¹). Bacterial 16S rDNA was then sequenced and analyzed using the next-generation sequencing technology. RESULT: Higher levels of N deposition resulted in an α-diversity increase followed by a decrease, with significant reductions in the HN treatment. Simulated nitrogen deposition resulted in changes in the structure and abundance of bacterial communities in wetland soils. The dominant phyla in all three plots were Proteobacteria and Acidobacteria. Compared with CK, the relative abundance of Chloroflexi increased significantly under the HN treatment (P < 0.05), whereas the relative abundance of Firmicutes and Bacteroidetes decreased significantly (P < 0.05). Nitrogen input changed the composition and relative abundance of the bacterial community, which was possibly due to N-induced soil acidification. CONCLUSION: This study thus provides a theoretical basis for predicting the effects of atmospheric nitrogen deposition on soil microorganisms, as well as changes in the wetland ecosystem in Sanjiang Plain.
    Keywords Acidobacteria ; Bacteroidetes ; Chloroflexi ; Firmicutes ; Proteobacteria ; bacterial communities ; bioactive compounds ; carbon ; functional diversity ; nitrogen ; soil acidification ; soil bacteria ; wetlands ; China
    Language English
    Dates of publication 2022-12
    Size p. 11.
    Publishing place BioMed Central
    Document type Article
    ZDB-ID 2143009-3
    ISSN 1869-2044 ; 1590-4261
    ISSN (online) 1869-2044
    ISSN 1590-4261
    DOI 10.1186/s13213-022-01666-8
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Non-contrast CT-based radiomic signature of pericoronary adipose tissue for screening non-calcified plaque.

    Jiang, Xing-Yuan / Shao, Zhi-Qing / Chai, Ya-Ting / Liu, Ying-Nan / Li, Ye

    Physics in medicine and biology

    2022  Volume 67, Issue 10

    Abstract: Objective. ...

    Abstract Objective.
    MeSH term(s) Adipose Tissue/diagnostic imaging ; Computed Tomography Angiography/methods ; Coronary Angiography/methods ; Coronary Artery Disease ; Humans ; Plaque, Atherosclerotic/diagnostic imaging ; Retrospective Studies ; Tomography, X-Ray Computed
    Language English
    Publishing date 2022-05-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 208857-5
    ISSN 1361-6560 ; 0031-9155
    ISSN (online) 1361-6560
    ISSN 0031-9155
    DOI 10.1088/1361-6560/ac69a7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Effects of bacteria on early-stage litter decomposition in Wudalianchi volcanic forest.

    Huang, Qing-Yang / Xie, Li-Hong / Cao, Hong-Jie / Wang, Li-Min / Yang, Fan / Wang, Ji-Feng / Liu, Ying-Nan / Ni, Hong-Wei

    Ying yong sheng tai xue bao = The journal of applied ecology

    2023  Volume 34, Issue 7, Page(s) 1941–1948

    Abstract: To understand the role of microorganisms in litter decomposition and nutrient cycling in volcanic forest ecosystem, we ... ...

    Title translation 细菌对五大连池火山森林凋落物早期分解的影响.
    Abstract To understand the role of microorganisms in litter decomposition and nutrient cycling in volcanic forest ecosystem, we conducted
    MeSH term(s) Forests ; Ecosystem ; Larix/metabolism ; Betula/metabolism ; Populus/metabolism ; Soil Microbiology ; Plant Leaves/metabolism ; Bacteria/metabolism ; Biomass
    Language English
    Publishing date 2023-09-09
    Publishing country China
    Document type Journal Article
    ZDB-ID 2881809-X
    ISSN 1001-9332
    ISSN 1001-9332
    DOI 10.13287/j.1001-9332.202307.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Aberrant activated Notch1 promotes prostate enlargement driven by androgen signaling via disrupting mitochondrial function in mouse.

    Kang, Jin-Wen / He, Jia-Peng / Liu, Ying-Nan / Zhang, Yu / Song, Shan-Shan / Xu, Qi-Xin / Wei, Shu-Wen / Lu, Lei / Meng, Xiang-Qi / Xu, Lin / Guo, Bin / Su, Ren-Wei

    Cellular and molecular life sciences : CMLS

    2024  Volume 81, Issue 1, Page(s) 155

    Abstract: The prostate is a vital accessory gonad in the mammalian male reproductive system. With the ever-increasing proportion of the population over 60 years of age worldwide, the incidence of prostate diseases, such as benign prostatic hyperplasia (BPH) and ... ...

    Abstract The prostate is a vital accessory gonad in the mammalian male reproductive system. With the ever-increasing proportion of the population over 60 years of age worldwide, the incidence of prostate diseases, such as benign prostatic hyperplasia (BPH) and prostate cancer (PCa), is on the rise and is gradually becoming a significant medical problem globally. The notch signaling pathway is essential in regulating prostate early development. However, the potential regulatory mechanism of Notch signaling in prostatic enlargement and hyperplasia remains unclear. In this study, we proved that overactivation of Notch1 signaling in mouse prostatic epithelial cells (OEx) led to prostatic enlargement via enhancing proliferation and inhibiting apoptosis of prostatic epithelial cells. Further study showed that N1ICD/RBPJ directly up-regulated the androgen receptor (AR) and enhanced prostatic sensitivity to androgens. Hyper-proliferation was not found in orchidectomized OEx mice without androgen supply but was observed after Dihydrotestosterone (DHT) supplementation. Our data showed that the number of mitochondrion in prostatic epithelial cells of OEx mice was increased, but the mitochondrial function was impaired, and the essential activity of the mitochondrial respiratory electron transport chain was significantly weakened. Disordered mitochondrial number and metabolic function further resulted in excessive accumulation of reactive oxygen species (ROS). Importantly, anti-oxidant N-Acetyl-L-Cysteine (NAC) therapy could alleviate prostatic hyperplasia caused by the over-activation of Notch1 signaling. Furthermore, we observed the incremental Notch signaling activity in progenitor-like club cells in the scRNA-seq data set of human BPH patients. Moreover, the increased number of TROP2
    MeSH term(s) Animals ; Humans ; Male ; Mice ; Androgens/metabolism ; Mammals/metabolism ; Mitochondria/metabolism ; Prostate/metabolism ; Prostatic Hyperplasia/metabolism ; Reactive Oxygen Species/metabolism ; Receptors, Androgen/genetics ; Receptors, Androgen/metabolism ; Signal Transduction
    Chemical Substances Androgens ; Reactive Oxygen Species ; Receptors, Androgen ; Notch1 protein, mouse
    Language English
    Publishing date 2024-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1358415-7
    ISSN 1420-9071 ; 1420-682X
    ISSN (online) 1420-9071
    ISSN 1420-682X
    DOI 10.1007/s00018-024-05143-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Comparison of Alternative Protein Hydrogels for Delivering Myricetin: Interaction Mechanism and Stability Evaluation.

    Wang, Wei / Wu, Yu-Ru / Li, Jing / Zhou, Qian / Yu, Zhen-Yu / Liu, Ying-Nan / Zheng, Ming-Ming / Zhou, Yi-Bin / Liu, Kang

    Journal of agricultural and food chemistry

    2024  Volume 72, Issue 15, Page(s) 8784–8797

    Abstract: Food protein carriers from different sources might have distinct stabilizing and enhancing effects on the same small molecule. To elucidate the molecular mechanism, five different sourced proteins including soy protein isolates (SPIs), whey protein ... ...

    Abstract Food protein carriers from different sources might have distinct stabilizing and enhancing effects on the same small molecule. To elucidate the molecular mechanism, five different sourced proteins including soy protein isolates (SPIs), whey protein isolates (WPIs), edible dock protein (EDP),
    MeSH term(s) Flavonoids/chemistry ; Micelles ; Hydrogels
    Chemical Substances myricetin (76XC01FTOJ) ; Flavonoids ; Micelles ; Hydrogels
    Language English
    Publishing date 2024-04-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.3c09896
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Effects of Simulated Nitrogen Deposition on Soil Microbial Carbon Metabolism in

    Weng, Xiao-Hong / Sui, Xin / Li, Meng-Sha / Liu, Ying-Nan / Zhang, Rong-Tao / Yang, Li-Bin

    Huan jing ke xue= Huanjing kexue

    2022  Volume 43, Issue 9, Page(s) 4674–4683

    Abstract: Atmospheric nitrogen deposition has a crucial impact on the structure and function of soil microorganisms of wetland ecosystems. Therefore, carrying out a study on the effects of soil carbon metabolism capacity has a great significance for the protection ...

    Abstract Atmospheric nitrogen deposition has a crucial impact on the structure and function of soil microorganisms of wetland ecosystems. Therefore, carrying out a study on the effects of soil carbon metabolism capacity has a great significance for the protection and utilization of wetland ecosystems. In this study, the effects of simulated nitrogen deposition on the carbon metabolic capacity of soil microorganisms in
    MeSH term(s) Amines/metabolism ; Carbohydrates ; Carbon/chemistry ; Ecosystem ; Nitrogen/analysis ; Poaceae ; Soil/chemistry ; Soil Microbiology ; Wetlands
    Chemical Substances Amines ; Carbohydrates ; Soil ; Carbon (7440-44-0) ; Nitrogen (N762921K75)
    Language Chinese
    Publishing date 2022-07-20
    Publishing country China
    Document type Journal Article
    ISSN 0250-3301
    ISSN 0250-3301
    DOI 10.13227/j.hjkx.202111288
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Vanillin prevents the growth of endometriotic lesions through anti-inflammatory and antioxidant pathways in a mouse model.

    Liu, Ying-Nan / Kang, Jin-Wen / Zhang, Yu / Song, Shan-Shan / Xu, Qi-Xin / Zhang, Han / Lu, Lei / Wei, Shu-Wen / Liang, Chen / Su, Ren-Wei

    Food & function

    2023  Volume 14, Issue 14, Page(s) 6730–6744

    Abstract: Endometriosis is an estrogen-dependent chronic inflammatory gynecological disease defined by the presence of endometrial glands and mesenchyme outside the uterine cavity, named ectopic endometrium. Recent studies showed that endometriosis is associated ... ...

    Abstract Endometriosis is an estrogen-dependent chronic inflammatory gynecological disease defined by the presence of endometrial glands and mesenchyme outside the uterine cavity, named ectopic endometrium. Recent studies showed that endometriosis is associated with hormone imbalance, inflammation and oxidative stress. As the main component of vanilla bean extract, vanillin is widely used as a flavoring agent in the food, pharmaceutical, and cosmetic industries. It is known for its anti-inflammatory, antibacterial, and antitumor properties, but its therapeutic efficacy in endometriosis has not been studied. In this study, we evaluated the roles of vanillin in this disease using an induced endometriotic mouse model. The results showed that vanillin significantly inhibited the growth of endometrial lesions. Compared with the control group, the weight and volume of lesions were reduced considerably in the vanillin-treated group, showing its fantastic ability to inhibit cell proliferation and promote apoptosis. In addition, in the treatment group, mRNA expression of the pro-inflammatory cytokines
    MeSH term(s) Adult ; Female ; Animals ; Mice ; Humans ; Endometriosis/drug therapy ; Endometriosis/genetics ; Endometriosis/metabolism ; Antioxidants/pharmacology ; Inflammation/drug therapy ; Pharmaceutical Preparations ; Anti-Inflammatory Agents/pharmacology
    Chemical Substances Antioxidants ; vanillin (CHI530446X) ; Pharmaceutical Preparations ; Anti-Inflammatory Agents
    Language English
    Publishing date 2023-07-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2612033-1
    ISSN 2042-650X ; 2042-6496
    ISSN (online) 2042-650X
    ISSN 2042-6496
    DOI 10.1039/d3fo00750b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Self-assembly and interaction mechanisms of edible dock protein and flavonoids regulated by the phenolic hydroxyl position.

    Zhou, Qian / Wang, Xiao-Jie / Li, Jing / Wu, Yu-Ru / Wang, Wei / Yu, Zhen-Yu / Xiao, Ya-Qing / Liu, Ying-Nan / Li, Shi-Yi / Zheng, Ming-Ming / Zhou, Yi-Bin / Liu, Kang

    Food chemistry

    2023  Volume 424, Page(s) 136383

    Abstract: In this study, chrysin (Chr), baicalein (Bai), apigenin (Api) and galangin (Gal) were selected as the representative flavonoids with different position of phenolic hydroxyl groups, and edible dock protein (EDP) was used as a material to construct ... ...

    Abstract In this study, chrysin (Chr), baicalein (Bai), apigenin (Api) and galangin (Gal) were selected as the representative flavonoids with different position of phenolic hydroxyl groups, and edible dock protein (EDP) was used as a material to construct delivery system. Subsequently, the molecular interactions and functional properties of flavonoids-loaded EDP nanomicelles were investigated. Results exhibited that hydrogen bond, hydrophobic interaction and van der Waals force were the main driving forces for self-assembly of flavonoids and EDP molecules. Meanwhile, this self-assembly remarkably enhance the storage and digestion stability of flavonoid compounds. Among four flavonoids, the order of loading ability was: Api > Gal > Bai > Chr. Herein, Api had a largest loading capacity (6.74%) because of its active phenolic hydroxyl group in ring B. These results suggested that the position of phenolic hydroxyl groups in flavonoids is a key factor to regulate its self-assembly with protein molecules.
    MeSH term(s) Flavonoids/chemistry ; Hydroxyl Radical ; Phenols
    Chemical Substances Flavonoids ; Hydroxyl Radical (3352-57-6) ; Phenols
    Language English
    Publishing date 2023-05-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2023.136383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Comprehensive Pan-Cancer Analysis of Heat Shock Protein 110, 90, 70, and 60 Families.

    Yan, Li-Rong / Shen, Shi-Xuan / Wang, Ang / Ding, Han-Xi / Liu, Ying-Nan / Yuan, Yuan / Xu, Qian

    Frontiers in molecular biosciences

    2021  Volume 8, Page(s) 726244

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-10-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2021.726244
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Socioeconomic and lifestyle determinants of the prevalence of hypertension among elderly individuals in rural southwest China: a structural equation modelling approach.

    Xiao, Li / Le, Cai / Wang, Gui-Yi / Fan, Lu-Ming / Cui, Wen-Long / Liu, Ying-Nan / Shen, Jing-Rong / Golden, Allison Rabkin

    BMC cardiovascular disorders

    2021  Volume 21, Issue 1, Page(s) 64

    Abstract: Background: This study examines the association between socioeconomic and lifestyle factors and the prevalence of hypertension among elderly individuals in rural Southwest China.: Methods: A cross-sectional survey of 4833 consenting adults aged ≥ 60 ... ...

    Abstract Background: This study examines the association between socioeconomic and lifestyle factors and the prevalence of hypertension among elderly individuals in rural Southwest China.
    Methods: A cross-sectional survey of 4833 consenting adults aged ≥ 60 years in rural regions of Yunnan Province, China, was conducted in 2017. Data on individual socioeconomic status, sleep quality, physical activity level, and family history of hypertension were collected with a standardized questionnaire. Blood pressure, fasting blood glucose, height, weight, and waist circumference were also measured. An individual socioeconomic position (SEP) index was constructed using principal component analysis. Structural equation modelling (SEM) was applied to analyse the association between socioeconomic and lifestyle factors and the prevalence of hypertension.
    Results: The overall prevalence of hypertension was 50.6% in the study population. Body fat distribution, including measures of obesity and central obesity, had the greatest total effect on hypertension (0.21), followed by family history of hypertension (0.14), biological sex (0.08), sleep quality (- 0.07), SEP (- 0.06), physical inactivity (0.06), and diabetes (0.06). Body fat distribution, SEP, and family history of hypertension had both direct and indirect effects on hypertension, whereas physical inactivity, diabetes, and sleep quality were directly associated with the prevalence of hypertension. Biological sex was indirectly associated with the prevalence of hypertension.
    Conclusions: SEP, body fat distribution, physical inactivity, diabetes, and sleep quality critically influence the prevalence of hypertension. Future interventions to prevent and control hypertension should give increased attention to individuals with low SEP and should focus on controlling diabetes and obesity, increasing physical activity levels, and improving quality of sleep among older adults aged ≥ 60 years in rural Southwest China.
    MeSH term(s) Adiposity ; Age Factors ; Aged ; Blood Pressure ; China/epidemiology ; Cross-Sectional Studies ; Diabetes Mellitus/epidemiology ; Female ; Health Surveys ; Humans ; Hypertension/diagnosis ; Hypertension/epidemiology ; Hypertension/physiopathology ; Latent Class Analysis ; Life Style ; Male ; Middle Aged ; Obesity/epidemiology ; Prevalence ; Risk Assessment ; Risk Factors ; Rural Health ; Sedentary Behavior ; Sleep ; Social Determinants of Health ; Socioeconomic Factors
    Language English
    Publishing date 2021-02-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2059859-2
    ISSN 1471-2261 ; 1471-2261
    ISSN (online) 1471-2261
    ISSN 1471-2261
    DOI 10.1186/s12872-021-01885-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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