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Book ; Online ; Conference proceedings: Marine Drug Research in China: Selected Papers from the 15-NASMD Conference

Zhou, Xuefeng / Luo, Xiaowei / Liu, Yonghong

2022

Keywords	Medicine ; Antarctic krill (Euphausia superba) ; peptide ; antioxidant activity ; stability ; oyster ; plasma ; peptidome ; antimicrobial peptides ; cytotoxicity ; actinomycete ; piericidins ; absolute configuration ; Pestalotiopsis heterocornis ; heterocornols ; anti-inflammatory activity ; sponge-derived fungus ; sclerotides ; lipodepsipeptide ; Aspergillus sclerotiorum ; nasopharyngeal carcinoma ; AChE inhibitory ; vascular endothelial cell ; flavonoid ; oxidized low-density lipoprotein ; Nrf2 ; apoptosis ; butyrolactone I ; food allergy ; metabolism ; pharmacokinetics ; actinomycin X2 ; microbial pigments ; dyeing ; silk ; antibacterial properties ; PD-L1 ; virtual screening ; pharmacophore modeling ; ADME ; molecular dynamics ; xanthones ; ascidian-derived fungus ; Diaporthe sp ; anti-glioma activity ; antiaging ; Sonneratia apetala ; signaling pathway ; Caenorhabditis elegans ; mutants ; coral-derived fungi ; Aspergillus hiratsukae ; meroterpenoids ; antibacterial activity ; cytotoxic activity ; deep-sea-derived fungus ; Aspergillus puniceus ; isoquinoline alkaloid ; protein tyrosine phosphatase inhibitor ; antibacterial ; Aspergillus sp ; geodin ; semisynthesize ; insecticidal activity ; Arca inflata ; antitumor peptide ; MAPK signaling ; calmodulin ; colorectal cancer ; methicillin-resistant Staphylococcus aureus ; actinomycin D ; Streptomyces parvulus ; mechanism ; mangrove endophytic Pestalotiopsis ; Sdy-1 ; antitumor activity ; Wnt signaling ; β-catenin ; eremophilane sesquiterpenoids ; mangrove-derived fungus ; Penicillium sp ; Oceanapia ; sponge ; secondary metabolites ; biological activities ; drug design ; anticancer ; cyclic pentapeptide ; galaxamide analogues ; skipjack tuna (Katsuwonus pelamis) muscle ; angiotensin-I-converting enzyme (ACE) peptide ; molecular docking ; nitric oxide (NO) ; endothelin-1 (ET-1) ; Trichoderma longibrachiatum ; sesquiterpene glycoside ; antimicrobial activity ; marine fungi ; Aspergillus unguis ; depsides ; depsidones ; osteoclast differentiation ; soft-coral-derived fungus ; pyranodipyran derivatives ; tyrosyl DNA phosphodiesterase 1 inhibitory activities ; fluorescent properties ; butenolides ; enantiomers ; Aspergillus terreus ; pancreatic lipase ; NAFLD ; fucoxanthin ; adenosine monophosphate-activated protein kinase (AMPK) ; nuclear factor erythroid-2-related factor 2-mediated (Nrf2) ; Toll-like receptor 4-mediated (TLR4) ; Aspergillus flavipes HN4-13 ; emodin ; macroporous resin XAD-16 ; adsorption kinetics and isotherms ; enrichment ; tetramic acid derivatives ; deep-sea fungus ; clavipitacae ; Lecanicillium fusisporum ; chronic kidney disease ; fucoidan ; cognitive dysfunction ; neuroinflammation ; oxidative stress ; GSK3β-Nrf2-HO-1 signaling ; microglial polarization ; deep-sea actinomycetes ; aromatic acids ; oximes ; antihyperlipidemic ; phycocyanin ; microbiota ; transcriptome ; IL-17 pathway ; Hahella ; prodiginine ; chejuenlide ; genome mining ; LC-MS/MS ; CDK4/6 ; marine compounds ; pharmacophore construction ; ADMET ; mm-pbsa
Language	0\|e
Size	1 electronic resource (512 pages)
Publisher	MDPI Books
Publishing place	Basel
Document type	Book ; Online ; Conference proceedings
Note	English ; Open Access
HBZ-ID	HT021618610
ISBN	9783036545707 ; 3036545700
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Stretching induced syncope associated with myoclonic jerks in a teenage boy.

Wang, Xiaoli / Liu, Yonghong

Epileptic disorders : international epilepsy journal with videotape

2023 Volume 25, Issue 6, Page(s) 914–916

MeSH term(s)	Male ; Adolescent ; Humans ; Myoclonus/diagnosis ; Myoclonus/etiology ; Syncope/etiology ; Electromyography ; Electroencephalography
Language	English
Publishing date	2023-09-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2086797-9
ISSN	1950-6945 ; 1294-9361
ISSN (online)	1950-6945
ISSN	1294-9361
DOI	10.1002/epd2.20153
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Zs.A 5740: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Zs.MN 11: Show issues

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Article ; Online: Late-onset narcolepsy type 1 comorbid with anti-IgLON5 disease in an older male patient.

Wang, Xiaoli / Yuan, Na / Zhang, Xinbo / Liu, Yonghong

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

2024 Volume 20, Issue 5, Page(s) 829–832

MeSH term(s)	Humans ; Narcolepsy/complications ; Male ; Aged ; Polysomnography ; Comorbidity ; Cell Adhesion Molecules, Neuronal
Chemical Substances	IgLON5 protein, human ; Cell Adhesion Molecules, Neuronal
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2397213-0
ISSN	1550-9397 ; 1550-9389
ISSN (online)	1550-9397
ISSN	1550-9389
DOI	10.5664/jcsm.11016
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Article ; Online: Chemotherapy-induced oral mucositis induced by low dose methotrexate

WANG Shanshan / MA Xixing / LI Yanling / LIU Yonghong

口腔疾病防治, Vol 31, Iss 9, Pp 660-

a case report and literature review

2023 Volume 669

Abstract: Objective To investigate the diagnosis and treatment for oral mucositis induced by low-dose methotrexate and to provide a reference for clinicians. Methods A case of severe chemotherapy-induced oral mucositis caused by short-term use of low-dose ... ...

Abstract	Objective To investigate the diagnosis and treatment for oral mucositis induced by low-dose methotrexate and to provide a reference for clinicians. Methods A case of severe chemotherapy-induced oral mucositis caused by short-term use of low-dose methotrexate (the maximum cumulative dose within 1 week) was reported and reviewed in combination with the literature. Results The patient was treated with low-dose methotrexate (2.5 mg orally every other day at weeks 1, 2, and 4; the third week, 2.5 mg each time for 3 consecutive days for twice, with a maximum cumulativedose of 15 mg within a week). After irregular medication for approximately three weeks, the patient gradually developed severe erosion of the lips, pain, difficulty eating, and skin erosion on both legs. Methotrexate was stopped after admission, and local symptomatic treatments such as Kangfuxin solution were given. Recombinant human granulocyte colony-stimulating factor was used systemically when combined with neutropenia. After treatment, the chemotherapy-induced oral mucositis and skin lesions were improved. A literature review shows that chemotherapy-induced oral mucositis is a toxic reaction to high-dose methotrexate, while cases of severe chemotherapy-induced oral mucositis caused by low-dose methotrexate are rare. Studies have found that the more risk factors patients have, such as poor local oral conditions and systemic diseases such as liver and kidney dysfunction and diabetes, the higher the risk of chemotherapy-induced oral mucositis. Clinicians should cooperate with dentists to address oral diseases as much as possible before using chemotherapy drugs. In addition, when ordering patients to take methotrexate, we should pay attention to the patient's general condition and susceptibility factors, standardize the frequency and dose of administration, adopt personalized treatment plans, and give patients detailed medication education to prevent the occurrence of adverse consequences caused by medication errors. If methotrexate poisoning occurs, ...
Keywords	methotrexate ; chemotherapy-induced oral mucositis ; psoriasis vulgaris ; myelosuppression ; chronic periodontitis ; granulocyte colony stimulating factor ; risk factors ; Medicine ; R
Subject code	610
Language	Chinese
Publishing date	2023-09-01T00:00:00Z
Publisher	Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Targeting androgen receptor in glioblastoma.

Gan, Xia / Liu, Yonghong / Wang, Xueni

Critical reviews in oncology/hematology

2023 Volume 191, Page(s) 104142

Abstract: Glioblastomas are primary brain tumors that originate from glial stem cells or progenitor cells. There is a large difference in the incidence of glioblastoma between males and females. Studies revealed that the gender differences in the tumor may be ... ...

Abstract	Glioblastomas are primary brain tumors that originate from glial stem cells or progenitor cells. There is a large difference in the incidence of glioblastoma between males and females. Studies revealed that the gender differences in the tumor may be attributable to the androgen receptor signaling axis. The incidence rate of glioblastoma in men is higher than that in women. Aberrant activation of the androgen receptor signaling pathway, or interactions between the androgen receptor signaling axis and other signaling axes promote the development of glioblastoma. Therefore, targeting the androgen receptor holds promise as a therapeutic approach for glioblastoma. This review investigates the dynamics of drug research into the treatment of glioblastoma by targeting the androgen receptor. The first finding in line with expectations is that androgen receptor antagonists, represented by enzalutamide, have been studied and shown to have anti-glioblastoma effects. In addition, it was found that the combination of 5-alpha reductase inhibitors and androgen receptor antagonists resulted in better therapeutic outcomes than each of them alone. Similar results were obtained with the combination of an epidermal growth factor receptor inhibitor and an androgen receptor antagonist. In addition, four small molecule compounds have been shown to exert significant anti-glioblastoma effects by directly or indirectly targeting the androgen receptor. Expectantly, one of these small molecules, seviteronel, progressed to the phase II clinical trial stage. These findings suggest that targeting the androgen receptor for glioblastoma may be a promising therapeutic option.
Language	English
Publishing date	2023-09-24
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	605680-5
ISSN	1879-0461 ; 0737-9587 ; 1040-8428
ISSN (online)	1879-0461
ISSN	0737-9587 ; 1040-8428
DOI	10.1016/j.critrevonc.2023.104142
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Article ; Online: Hantzsch Esters Enabled [2π+2σ] Cycloadditions of Bicyclo [1.1.0] butanes and Alkenes under Photo Conditions.

Yan, Huaipu / Liu, Yonghong / Feng, Xiao / Shi, Lei

Organic letters

2023 Volume 25, Issue 45, Page(s) 8116–8120

Abstract: Hantzsch esters (HEs) are widely recognized as sources of hydride ions (H-) and sacrificial electron donors in their ground state. Here, we report the application of HE as a mediator in [2π+2σ] cycloaddition of bicyclo[1.1.0]butanes (BCBs) with alkenes ... ...

Abstract	Hantzsch esters (HEs) are widely recognized as sources of hydride ions (H-) and sacrificial electron donors in their ground state. Here, we report the application of HE as a mediator in [2π+2σ] cycloaddition of bicyclo[1.1.0]butanes (BCBs) with alkenes under photo conditions. Through this strategy, various substituted bicyclo[2.1.1]hexanes can be efficiently prepared.
Language	English
Publishing date	2023-11-08
Publishing country	United States
Document type	Journal Article
ISSN	1523-7052
ISSN (online)	1523-7052
DOI	10.1021/acs.orglett.3c03222
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Iron-Promoted Catalytic Activity of Selenium Endowing the Aerobic Oxidative Cracking Reaction of Alkenes.

Li, Xiaoxue / Hua, Hangzhou / Liu, Yonghong / Yu, Lei

Organic letters

2023 Volume 25, Issue 36, Page(s) 6720–6724

Abstract: Oxidative cracking of alkenes is a significant process in industry. In this work, it was found that catalyzed by Se/Fe via hybrid mechanisms, the carbon-carbon double bond in alkenes can break to produce carbonyls under mild conditions. Since ... ...

Abstract	Oxidative cracking of alkenes is a significant process in industry. In this work, it was found that catalyzed by Se/Fe via hybrid mechanisms, the carbon-carbon double bond in alkenes can break to produce carbonyls under mild conditions. Since O
Language	English
Publishing date	2023-09-07
Publishing country	United States
Document type	Journal Article
ISSN	1523-7052
ISSN (online)	1523-7052
DOI	10.1021/acs.orglett.3c02569
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: An earphone fit deviation analysis algorithm.

Yan, Yan / Liu, Yonghong / Wang, Haining

Scientific reports

2023 Volume 13, Issue 1, Page(s) 1084

Abstract: This study provides an accurate method for evaluating the fit of earphones, which could be used for establishing a linkage between interference/gap values with human perception. Seven commercial CAD software tools stood out and were explored for the ... ...

Abstract	This study provides an accurate method for evaluating the fit of earphones, which could be used for establishing a linkage between interference/gap values with human perception. Seven commercial CAD software tools stood out and were explored for the analysis of the deviation between earphone and ear. However, the current deviation analysis method remains to be improved for earphone fit evaluation due to excessive points in the calculation (Geomagic Wrap and Siemens NX), lack of value on interference (Geomagic Control X), computation boundary required (Rapidform XOR/Redesign), repetitive computation with same points and inclined calculation line segment or even invalid calculation (Solidworks, Creo). Therefore, an accurate deviation analysis algorithm was promoted, which calculated the deviation between earphone and ear exactly and classified the interference set and gap set precisely. There are five main procedures of this algorithm, which are point cloud model pre-processing, the generation of distance vectors, the discrimination of interference set and gap set, the discrimination of validity, and statistical analysis and visualization. Furthermore, the usability and validity of the deviation analysis algorithm were verified through statistical analysis and comparing visual effects based on the earphone-wearing experiment. It is certified that the deviation analysis algorithm is appropriate for earphone fit evaluation and the eight indexes of this algorithm were proved to be related to subjective comfort scores. It is meaningful for ear-worn product fit analysis, design, and development phases.
MeSH term(s)	Humans ; Hearing Aids ; Software ; Algorithms
Language	English
Publishing date	2023-01-19
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-27794-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Role of tillage measures in mitigating waterlogging damage in rapeseed.

Tian, Xiaoqin / Li, Zhuo / Liu, Yonghong / Li, Wei

BMC plant biology

2023 Volume 23, Issue 1, Page(s) 231

Abstract: Background: Tillage measures have been effectively adopted for mitigating waterlogging damage in field crops, yet little is known about the role of tillage measures in crop responses to waterlogging. A field experiment was performed to investigate the ... ...

Abstract	Background: Tillage measures have been effectively adopted for mitigating waterlogging damage in field crops, yet little is known about the role of tillage measures in crop responses to waterlogging. A field experiment was performed to investigate the effect of conventional planting (CK), small ridge planting (SR), big ridge planting (BR) and film side planting (FS) on soil available nutrients and enzymatic activity, chlorophyll contents, leaf nutrients, soluble protein, soluble sugar, nitrate reductase, antioxidant enzyme activity, lipid peroxidation, agronomic traits and yield of rapeseed under waterlogging stress conditions. Results: Tillage measures remarkably improved rapeseed growth and yield parameters under waterlogging stress conditions. Under waterlogging conditions, rapeseed yield was significantly increased by 33.09 and 22.70% in the SR and BR groups, respectively, compared with CK. Correlation analysis showed that NO Conclusion: Overall, SR and BR mitigated the waterlogging damage in rapeseed mainly by reducing the loss of soil available nitrogen, decreasing the MDA content in roots, and promoting urease in soils and SOD and nitrate reductase in roots. Finally, thorough assessment of rapeseed parameters indicated that SR treatment was most effective followed by BR treatment, to alleviate the adverse effects of waterlogging stress.
MeSH term(s)	Brassica napus/metabolism ; Urease/metabolism ; Soil ; Brassica rapa/metabolism ; Superoxide Dismutase/metabolism ; Chlorophyll/metabolism ; Antioxidants/metabolism ; Nitrate Reductase/metabolism ; Sugars/metabolism
Chemical Substances	Urease (EC 3.5.1.5) ; Soil ; Superoxide Dismutase (EC 1.15.1.1) ; Chlorophyll (1406-65-1) ; Antioxidants ; Nitrate Reductase (EC 1.7.99.4) ; Sugars
Language	English
Publishing date	2023-05-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2059868-3
ISSN	1471-2229 ; 1471-2229
ISSN (online)	1471-2229
ISSN	1471-2229
DOI	10.1186/s12870-023-04250-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Mitigation strategies for excessive cadmium in rice.

Song, Jun / Song, Qiuchi / Wang, Dong / Liu, Yonghong

Comprehensive reviews in food science and food safety

2023 Volume 22, Issue 5, Page(s) 3847–3869

Abstract: Cadmium (Cd)-contaminated rice is a human food safety problem that lacks a clear solution. A large amount of rice having an excessive Cd content is processed yearly, but it cannot be discarded and placed in landfills because it will cause secondary ... ...

Abstract	Cadmium (Cd)-contaminated rice is a human food safety problem that lacks a clear solution. A large amount of rice having an excessive Cd content is processed yearly, but it cannot be discarded and placed in landfills because it will cause secondary pollution. How do we best cope with this toxic rice? From the perspectives of food safety, food waste prevention, and human hunger eradication, the use of contemporary physical, chemical, and biological techniques to lower the Cd content in postharvest Cd-contaminated rice so that it can be used safely is the best course of action. In this review, the contamination, chemical speciation, and distribution of Cd in rice are analyzed and discussed, as are the methods of Cd removal from rice, including a comparison of the advantages and disadvantages of various techniques. Owing to the limitations of current technology, research and technological development recommendations for removing Cd from rice grain are presented. The chemical and biological methods produce higher Cd-removal rates than physical methods. However, they are limited to small-scale laboratory applications and cannot be applied on a large industrial scale. For the efficient safe removal of Cd from food, mixed fermentation with lactic acid bacteria and yeast has good application prospects. However, limited strains having high Cd-removal rates have been screened. In addition, modern biotechnology has rarely been applied to reduce rice Cd levels. Therefore, applying genetic engineering techniques to rapidly obtain microorganisms with high Cd-removal rates in rice should be the focus of future research.
MeSH term(s)	Humans ; Cadmium/analysis ; Cadmium/toxicity ; Oryza/chemistry ; Soil Pollutants/analysis ; Soil Pollutants/toxicity ; Refuse Disposal ; Edible Grain/chemistry
Chemical Substances	Cadmium (00BH33GNGH) ; Soil Pollutants
Language	English
Publishing date	2023-07-17
Publishing country	United States
Document type	Review ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2185829-9
ISSN	1541-4337 ; 1541-4337
ISSN (online)	1541-4337
ISSN	1541-4337
DOI	10.1111/1541-4337.13210
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