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  1. Article: Analysis of Intraoperative Variables Responsible for the Increase in Lactic Acid in Patients Undergoing Debulking Surgery.

    Soriano Hervás, Marta / Robles-Hernández, Daniel / Serra, Anna / Játiva-Porcar, Rosa / Gómez Quiles, Luis / Maiocchi, Karina / Llorca, Sara / Climent, María Teresa / Llueca, Antoni

    Journal of personalized medicine

    2023  Volume 13, Issue 11

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2023-10-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm13111540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Hemoperitoneum caused by spontaneous rupture of the umbilical vein in cirrhosis.

    Marti, Josep / Llorca, Sara / Suñol, Xavier

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2013  Volume 11, Issue 1, Page(s) A38

    MeSH term(s) Hemoperitoneum/diagnosis ; Hemoperitoneum/pathology ; Humans ; Liver Cirrhosis/complications ; Male ; Middle Aged ; Radiography, Abdominal ; Rupture, Spontaneous/complications ; Rupture, Spontaneous/pathology ; Tomography, X-Ray Computed ; Umbilical Veins/pathology
    Language English
    Publishing date 2013-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2012.07.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Neoadjuvant Chemotherapy plus Interval Cytoreductive Surgery with or without Hyperthermic Intraperitoneal Chemotherapy (NIHIPEC) in the Treatment of Advanced Ovarian Cancer: A Multicentric Propensity Score Study.

    Llueca, Antoni / Ibañez, Maria Victoria / Cascales, Pedro / Gil-Moreno, Antonio / Bebia, Vicente / Ponce, Jordi / Fernandez, Sergi / Arjona-Sanchez, Alvaro / Muruzabal, Juan Carlos / Veiga, Nadia / Diaz-Feijoo, Berta / Celada, Cristina / Gilabert-Estelles, Juan / Aghababyan, Cristina / Lacueva, Javier / Calero, Alicia / Segura, Juan Jose / Maiocchi, Karina / Llorca, Sara /
    Villarin, Alvaro / Climent, Maria Teresa / Delgado, Katty / Serra, Anna / Gomez-Quiles, Luis / Llueca, Maria / On Behalf Of Spain Gog And Gecop Working Group

    Cancers

    2023  Volume 15, Issue 17

    Abstract: Introduction: Epithelial ovarian cancer (EOC) is primarily confined to the peritoneal cavity. When primary complete surgery is not possible, neoadjuvant chemotherapy (NACT) is provided; however, the peritoneum-plasma barrier hinders the drug effect. The ...

    Abstract Introduction: Epithelial ovarian cancer (EOC) is primarily confined to the peritoneal cavity. When primary complete surgery is not possible, neoadjuvant chemotherapy (NACT) is provided; however, the peritoneum-plasma barrier hinders the drug effect. The intraperitoneal administration of chemotherapy could eliminate residual microscopic peritoneal tumor cells and increase this effect by hyperthermia. Intraperitoneal hyperthermic chemotherapy (HIPEC) after interval cytoreductive surgery could improve outcomes in terms of disease-free survival (DFS) and overall survival (OS).
    Materials and methods: A multicenter, retrospective observational study of advanced EOC patients who underwent interval cytoreductive surgery alone (CRSnoH) or interval cytoreductive surgery plus HIPEC (CRSH) was carried out in Spain between 07/2012 and 12/2021. A total of 515 patients were selected. Progression-free survival (PFS) and OS analyses were performed. The series of patients who underwent CRSH or CRSnoH was balanced regarding the risk factors using a statistical analysis technique called propensity score matching.
    Results: A total of 170 patients were included in each subgroup. The complete surgery rate was similar in both groups (79.4% vs. 84.7%). The median PFS times were 16 and 13 months in the CRSH and CRSnoH groups, respectively (Hazard ratio (HR) 0.74; 95% CI, 0.58-0.94;
    Conclusion: The addition of HIPEC after interval cytoreductive surgery is safe and increases DFS in advanced EOC patients.
    Language English
    Publishing date 2023-08-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15174271
    Database MEDical Literature Analysis and Retrieval System OnLINE

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