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  1. Article: Radiofrequency Ablation of Small Renal Masses: Outcomes, Complications and Effects on Renal Function.

    Curry, David / Pahuja, Ajay / Loan, Willie / Thwaini, Ali

    Current urology

    2018  Volume 11, Issue 4, Page(s) 196–200

    Abstract: Introduction: To describe oncological outcomes, effects on renal function and complications with radiofrequency ablation (RFA) of T1 renal tumors in an 8-year experience.: Materials and methods: A retrospective study of RFA in 89 consecutive patients ...

    Abstract Introduction: To describe oncological outcomes, effects on renal function and complications with radiofrequency ablation (RFA) of T1 renal tumors in an 8-year experience.
    Materials and methods: A retrospective study of RFA in 89 consecutive patients between 2005 and 2013 was undertaken. Those with metastatic disease, incomplete follow-up, genetic pre-disposition to renal tumors and biopsy proven benign pathology were excluded, with 79 patients meeting inclusion criteria. Data was collected on demographics, oncological outcomes, complications and effects on renal function.
    Results: We demonstrate 94% disease-free survival at median follow-up of 29 months in a population consisting of 42 T1a and 37 T1b tumors. No disease related deaths were recorded in the follow-up period. Post-RFA decline in renal function was shown to correlate with tumor size and increased age (p = 0.0009/0.0021). Pre-existing renal impairment was a risk for post-RFA function decline (p < 0.005). Two complications were encountered in the series.
    Conclusion: RFA produces durable oncological outcomes in T1 tumors with a minimal effect on renal function and low risk of complications. Patients at risk of developing renal impairment can be identified from described risk factors.
    Language English
    Publishing date 2018-03-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2253664-4
    ISSN 1661-7657 ; 1661-7649
    ISSN (online) 1661-7657
    ISSN 1661-7649
    DOI 10.1159/000447218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6628: Show issues Location:
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  2. Article: Radiofrequency ablation of renal cell carcinoma: a follow up of outcomes.

    Curry, David / Yassin, Musaab / Thwaini, Ali / Pahuja, Ajay / Alanbuki, Ammar H / Rajan, Thiagarajan Nambi / Loan, Willie

    The Canadian journal of urology

    2014  Volume 21, Issue 1, Page(s) 7135–7140

    Abstract: Introduction: To present the oncological outcomes in a series of patients with cT1a renal cell carcinoma (RCC) treated with radiofrequency ablation (RFA) and its effect on the glomerular filtration rate (GFR).: Materials and methods: Forty-five ... ...

    Abstract Introduction: To present the oncological outcomes in a series of patients with cT1a renal cell carcinoma (RCC) treated with radiofrequency ablation (RFA) and its effect on the glomerular filtration rate (GFR).
    Materials and methods: Forty-five patients (48 renal units) treated at the Belfast City Hospital, over 4 years. Average age is 61.5 years (range 41-80). Eighteen patients (22 renal units) were included with American Society of Anesthesiologists (ASA) II and III. The rest were ASA I. Average tumor size was 2.63 cm (range 1.2 cm-6 cm). Renal function before and after RFA was recorded by means of the estimated glomerular filtration rate (eGFR) and the changes are presented. Oncological outcomes were established from follow up imaging. A satisfactory response was defined by disappearance or a persistence of non-enhancing lesion of smaller size at follow up. A partial response was defined by a persistent but non-enhancing similar size lesion. A failed response was defined by enlarging or persistently enhancing lesions.
    Results: Mean follow up was 30.6 months (4-60 months). A good response was found in 33 (74%) patients. A partial response was found in 3 (8%) patients and failed response was identified in 8 (18%) patients. The average reduction in eGFR was 11 mL/min. Two patients had a 50% reduction in their eGFR. No patient required dialysis following treatment.
    Conclusion: RFA presents safe treatment choice for patients with RCC, particularly those that are high risk surgical candidates and those who refuse surgery. Short term results suggest good oncological outcomes and preservation of renal function.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Carcinoma, Renal Cell/pathology ; Carcinoma, Renal Cell/physiopathology ; Carcinoma, Renal Cell/surgery ; Catheter Ablation/adverse effects ; Follow-Up Studies ; Glomerular Filtration Rate ; Humans ; Kidney Neoplasms/pathology ; Kidney Neoplasms/physiopathology ; Kidney Neoplasms/surgery ; Middle Aged ; Retreatment ; Retrospective Studies ; Treatment Failure ; Tumor Burden
    Language English
    Publishing date 2014-02
    Publishing country Canada
    Document type Journal Article ; Review
    ZDB-ID 2064475-9
    ISSN 1195-9479
    ISSN 1195-9479
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5607: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: The skiers knee without swelling or instability, a difficult diagnosis

    O'Donnell Mark E / Badger Stephen A / Campbell David / Loan Willie / Sinnott Brendan

    Journal of Medical Case Reports, Vol 1, Iss 1, p

    a case report

    2007  Volume 11

    Abstract: Abstract Skiing as a recreational activity has increased exponentially in the last twenty-years. Similar to any sporting activity, participants can sustain various types of injury, which provides the emergency departments with a continuous supply of ... ...

    Abstract Abstract Skiing as a recreational activity has increased exponentially in the last twenty-years. Similar to any sporting activity, participants can sustain various types of injury, which provides the emergency departments with a continuous supply of patients. The injury pattern from the slopes has also changed over this time period, due to alterations and improvements in ski equipment. An increased diversity in alpine skiing techniques, as well as snowboarding and cross-terrain disciplines has also influenced this change. We present a multi-media experience of a high-speed ski fall that caused a valgus-external rotation injury to the right knee that precluded the patient from further ski activity. There was no bruising, swelling or instability demonstrated and the patient returned to ski activities 24-hours post-injury. Although this injury appeared clinically benign initially, the patient complained of persistent pain around the right knee which was causing occupational difficulties. Following normal clinical assessment, the patient returned to work but continued to complain of persistent pain at the lateral aspect of the right knee. Magnetic Resonance Imaging (MRI) demonstrated extensive bone marrow oedema (BMO), a mild depression of the articular cortex compression with a small focus of articular cartilage disruption and microfractures of the lateral tibial plateau. The patient was treated conservatively and remains well with avoidance of impact exercises 14-months post-injury. In the presence of any high speed injury, we would stress that regardless of initial normal investigations, clinical suspicion should remain paramount and not deter the physician from further investigation in the presence of continuing symptomatology.
    Keywords Medicine ; R
    Subject code 616
    Language English
    Publishing date 2007-04-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: The skiers knee without swelling or instability, a difficult diagnosis: a case report.

    O'donnell, Mark E / Badger, Stephen A / Campbell, David / Loan, Willie / Sinnott, Brendan

    Journal of medical case reports

    2007  Volume 1, Page(s) 11

    Abstract: Skiing as a recreational activity has increased exponentially in the last twenty-years. Similar to any sporting activity, participants can sustain various types of injury, which provides the emergency departments with a continuous supply of patients. The ...

    Abstract Skiing as a recreational activity has increased exponentially in the last twenty-years. Similar to any sporting activity, participants can sustain various types of injury, which provides the emergency departments with a continuous supply of patients. The injury pattern from the slopes has also changed over this time period, due to alterations and improvements in ski equipment. An increased diversity in alpine skiing techniques, as well as snowboarding and cross-terrain disciplines has also influenced this change.We present a multi-media experience of a high-speed ski fall that caused a valgus-external rotation injury to the right knee that precluded the patient from further ski activity. There was no bruising, swelling or instability demonstrated and the patient returned to ski activities 24-hours post-injury. Although this injury appeared clinically benign initially, the patient complained of persistent pain around the right knee which was causing occupational difficulties. Following normal clinical assessment, the patient returned to work but continued to complain of persistent pain at the lateral aspect of the right knee. Magnetic Resonance Imaging (MRI) demonstrated extensive bone marrow oedema (BMO), a mild depression of the articular cortex compression with a small focus of articular cartilage disruption and microfractures of the lateral tibial plateau. The patient was treated conservatively and remains well with avoidance of impact exercises 14-months post-injury.In the presence of any high speed injury, we would stress that regardless of initial normal investigations, clinical suspicion should remain paramount and not deter the physician from further investigation in the presence of continuing symptomatology.
    Language English
    Publishing date 2007-04-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947
    ISSN 1752-1947
    DOI 10.1186/1752-1947-1-11
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Techniques in occluding the aorta during endovascular repair of ruptured abdominal aortic aneurysms.

    O'Donnell, Mark Edward / Badger, Stephen A / Makar, Ragai R / Loan, Willie / Lee, Bernard / Soong, Chee V

    Journal of vascular surgery

    2006  Volume 44, Issue 1, Page(s) 211–215

    Abstract: Among various methods to achieve rapid occlusion of the aorta during endovascular repair for ruptured abdominal aortic aneurysm, particular emphasis is placed on two techniques that have been incorporated into our endovascular repair practice. The sheath- ...

    Abstract Among various methods to achieve rapid occlusion of the aorta during endovascular repair for ruptured abdominal aortic aneurysm, particular emphasis is placed on two techniques that have been incorporated into our endovascular repair practice. The sheath-over-balloon technique (the Loan SOB technique) facilitates hemodynamic stability by transfemoral endovascular placement of an aortic occlusion balloon catheter to the infrarenal abdominal aorta. The balloon-ahead-of-graft technique (the Hornsby BAG technique) allows suprarenal hemodynamic control using a stent-graft system with a built-in balloon. The two techniques are simple, quick, and effective in achieving hemodynamic stability.
    MeSH term(s) Aneurysm, Ruptured/surgery ; Aortic Aneurysm, Abdominal/surgery ; Balloon Occlusion/methods ; Blood Vessel Prosthesis Implantation/methods ; Catheterization/methods ; Femoral Artery/diagnostic imaging ; Fluoroscopy ; Hemorrhage/prevention & control ; Humans
    Language English
    Publishing date 2006-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605700-7
    ISSN 1097-6809 ; 0741-5214
    ISSN (online) 1097-6809
    ISSN 0741-5214
    DOI 10.1016/j.jvs.2006.03.033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1933: Show issues Location:
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