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  1. AU="Lobo, Brian C"
  2. AU=Zhuang Jianjian AU=Zhuang Jianjian
  3. AU=Pathanki Adithya M
  4. AU="Armando Vilchis-Ordoñez"
  5. AU="Zhongfu Lu"
  6. AU="Lo, Hong-Yip"
  7. AU="Ziman Xiong"
  8. AU="Oakes, Allison H"
  9. AU="Ma, Shaotong"
  10. AU="Zang, Lili"
  11. AU="Adams Brian D"
  12. AU="Maria Papaioannou"
  13. AU="Kollia, Georgia"
  14. AU="Auxiette, Catherine"
  15. AU="Guzmán, Luis"
  16. AU="Alipour, Elnaz"
  17. AU="Queiroz, Dayanna Joyce Marques"
  18. AU="Ramamurthy, Santosh"
  19. AU="Xueying Huang"
  20. AU="Cromwell, Howard C"
  21. AU="Spence, John C H"
  22. AU="Chapinal, Libertad"
  23. AU=Rohaim Mohammed A AU=Rohaim Mohammed A
  24. AU=Hempel Cornelius

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  1. Artikel ; Online: Reflecting on the Work of the Giants That Come Before You.

    Lobo, Brian C

    American journal of rhinology & allergy

    2021  Band 36, Heft 1, Seite(n) 5–7

    Sprache Englisch
    Erscheinungsdatum 2021-12-06
    Erscheinungsland United States
    Dokumenttyp Editorial
    ZDB-ID 2482804-X
    ISSN 1945-8932 ; 1945-8924
    ISSN (online) 1945-8932
    ISSN 1945-8924
    DOI 10.1177/19458924211063613
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Sinonasal and Skull Base Metastatic Renal Cell Carcinoma: A Case Series.

    Hess, Andrew O / Terry, Russell S / Lobo, Brian C / Justice, Jeb M

    Cureus

    2023  Band 15, Heft 11, Seite(n) e48757

    Abstract: Metastatic lesions to the paranasal sinuses and skull base, while rare, carry a poor prognosis. Renal cell carcinoma has been reported in multiple case reports to be one of the most common distant malignancies to spread to the paranasal sinuses; however, ...

    Abstract Metastatic lesions to the paranasal sinuses and skull base, while rare, carry a poor prognosis. Renal cell carcinoma has been reported in multiple case reports to be one of the most common distant malignancies to spread to the paranasal sinuses; however, it is often unrecognized by physicians, and thus treatment is delayed. To increase awareness of this disease process, we describe three cases of metastatic renal cell carcinoma to the sinonasal cavity, which is the largest case series in the literature to date.
    Sprache Englisch
    Erscheinungsdatum 2023-11-13
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.48757
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Non-tuberculous Mycobacterium Rhinosinusitis in an Immunocompetent Patient.

    Tomlinson, Michelle G / Chidarala, Shreya / Lobo, Brian C / Kalyatanda, Gautam S

    Cureus

    2023  Band 15, Heft 8, Seite(n) e44002

    Abstract: Non-tuberculous mycobacteria (NTM) are slow-growing opportunistic pathogens that cause a variety of cutaneous, soft tissue, and pulmonary infections. On rare occasions, NTM causes chronic rhinosinusitis, with the majority of cases presenting in ... ...

    Abstract Non-tuberculous mycobacteria (NTM) are slow-growing opportunistic pathogens that cause a variety of cutaneous, soft tissue, and pulmonary infections. On rare occasions, NTM causes chronic rhinosinusitis, with the majority of cases presenting in immunocompromised individuals. Other potential risk factors include the presence of foreign bodies, previous sinus surgery or chemoradiation, and use of contaminated water in sinus rinses. We report here a rare case of NTM rhinosinusitis in an otherwise immunocompetent 66-year-old female. The patient underwent functional endoscopic sinus surgery where intraoperative acid-fast bacteria cultures grew
    Sprache Englisch
    Erscheinungsdatum 2023-08-23
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.44002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: The Transverse Turbinate Line: A Reliable Landmark for the Maxillary Sinus Natural Ostium.

    Comer, Julia C / Hess, Andrew O / Rarey, Kyle E / Justice, Jeb M / Collins, William O / Lobo, Brian C

    The Laryngoscope

    2023  Band 133, Heft 12, Seite(n) 3285–3291

    Abstract: Objectives: Approximating the maxillary sinus natural ostium's (MSNO) natural position during anterograde surgery is challenging, as only a single visual "landmark," the maxillary line, is routinely offered to guide the identification of the MSNO in ... ...

    Abstract Objectives: Approximating the maxillary sinus natural ostium's (MSNO) natural position during anterograde surgery is challenging, as only a single visual "landmark," the maxillary line, is routinely offered to guide the identification of the MSNO in three-dimensional space. Despite almost 40 years of endoscopic sinus surgery (ESS) experience in North America, maxillary recirculation and discontinuity between the natural and surgical ostia are commonly encountered during revision ESS. Consequently, we feel an additional visual landmark would assist in localizing the MSNO with or without image guidance. In this study, we aim to provide a second reliable landmark in the sinonasal cavity.
    Methods: We present a cadaveric anatomical landmark series that provides a second visual landmark for the MSNO, which we have labeled the transverse turbinate line (TTL): a 2-millimeter zone of confidence for the craniocaudal positioning of the MSNO that can be combined with the anteroposterior (AP) landmark of the maxillary line.
    Results: In our study, 40 cadaveric sinuses were dissected, and the TTL was found to correspond consistently with the zone between the superior and inferior aspects of the MSNO.
    Conclusion: We anticipate that this second relational landmark may decrease the time required for anterograde access to the MSNO in trainees, increase the accuracy of identification, and translate to lower long-term recirculation and maxillary surgery failure rates.
    Level of evidence: NA Laryngoscope, 133:3285-3291, 2023.
    Mesh-Begriff(e) Humans ; Maxillary Sinus/surgery ; Turbinates/surgery ; Endoscopy/methods ; Laryngoscopes ; Cadaver
    Sprache Englisch
    Erscheinungsdatum 2023-05-03
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.30678
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Utilization of Nasal Mucus to Investigate the Pathophysiology of Chronic Rhinosinusitis.

    Parra-Ferro, Mauricio / Justice, Jeb M / Lobo, Brian C / Munger, Steven D / Schlosser, Rodney J / Mulligan, Jennifer K

    American journal of rhinology & allergy

    2022  Band 36, Heft 6, Seite(n) 872–883

    Abstract: Background: Nasal mucus is proving to be a useful means by which to study the pathogenesis of chronic rhinosinusitis (CRS). Given the increase in publications examining nasal mucus and the lack of a review on this topic, we will focus on this ... ...

    Abstract Background: Nasal mucus is proving to be a useful means by which to study the pathogenesis of chronic rhinosinusitis (CRS). Given the increase in publications examining nasal mucus and the lack of a review on this topic, we will focus on this noninvasive approach to studying CRS. Particular attention will be drawn towards inflammatory cytokines and biomarkers and their influence on disease severity.
    Methods: A literature review of papers published in English pertaining to nasal mucus was performed using the PubMed database. The search utilized combinations of the following keywords: sinusitis, polyps, sample collection, nasal mucus, or nasal secretion. Studies solely on acute or bacterial sinusitis, allergic rhinitis, or cystic fibrosis were not included.
    Results: A wide variety of materials and methods have been used to collect nasal mucus. Numerous assay types have been performed with the most common being ELISA, cytometric bead array, and proteomics. Most studies have focused on examining the levels of Th1/Th2 cytokines along with chemokines associated with type 2 immunity. Other factors identified include growth factors, senescence-associated proteins, complement, and antimicrobial defenses have also been identified. Nasal mucus cytokines have proven useful in cluster analysis and predicting postoperative improvement in Sino-nasal Outcome Test (SNOT-22) scores. One limitation of the use of nasal mucus is that some studies have suggested that nasal mucus does not always reflect the tissue microenvironment.
    Conclusions: Nasal mucus represents a critical tool by which to examine the sinonasal microenvironment in a noninvasive manner. Unlike studies of tissue, it can be utilized in both surgically and medically managed patients and avoids the trauma of biopsies. However, studies are still needed to determine the most effective method for nasal mucus collection. Studies should also take care to confirm that nasal mucus markers do, in fact, reflect the levels of the product studied in the tissue.
    Mesh-Begriff(e) Biomarkers/metabolism ; Chronic Disease ; Cytokines/metabolism ; Humans ; Mucus/metabolism ; Nasal Polyps ; Rhinitis ; Sinusitis
    Chemische Substanzen Biomarkers ; Cytokines
    Sprache Englisch
    Erscheinungsdatum 2022-07-17
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2482804-X
    ISSN 1945-8932 ; 1945-8924
    ISSN (online) 1945-8932
    ISSN 1945-8924
    DOI 10.1177/19458924221111830
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Konferenzbeitrag: Postoperative Pneumocephalus following Labyrinthectomy for Meniere's Disease: A Case Report

    Hess, Andrew O. / Poynter, Jacob W. / Justice, Jeb M. / Lobo, Brian C. / Chen, Si / Haberman, Rex S.

    Journal of Neurological Surgery Part B: Skull Base

    2023  Band 84, Heft S 01

    Veranstaltung/Kongress 32nd Annual Meeting North American Skull Base Society, JW Marriott Tampa Water Street, Tampa, Florida, United States, 2023-02-17
    Sprache Englisch
    Erscheinungsdatum 2023-02-01
    Verlag Georg Thieme Verlag KG
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel ; Konferenzbeitrag
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0043-1762263
    Datenquelle Thieme Verlag

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  7. Artikel ; Konferenzbeitrag: Discrepancies between Patient Reported and Objective Olfactory Function before Endoscopic Skull Base Surgery

    Jackson, Lindsey F. / Mulligan, Jennifer K. / Justice, Jeb M. / Roper, Steven N. / Blatt, Jason E. / Lobo, Brian C.

    Journal of Neurological Surgery Part B: Skull Base

    2023  Band 84, Heft S 01

    Veranstaltung/Kongress 32nd Annual Meeting North American Skull Base Society, JW Marriott Tampa Water Street, Tampa, Florida, United States, 2023-02-17
    Sprache Englisch
    Erscheinungsdatum 2023-02-01
    Verlag Georg Thieme Verlag KG
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel ; Konferenzbeitrag
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0043-1762033
    Datenquelle Thieme Verlag

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  8. Artikel: Significant Underreporting of Preoperative Hyposmia in Patients Undergoing Endoscopic Skull Base Surgery: Discrepancies Between Subjective and Objective Measurements

    Jackson, Lindsey F. / Mulligan, Jennifer K. / Justice, Jeb M. / Roper, Steven N. / Blatt, Jason E. / Lobo, Brian C.

    Journal of Neurological Surgery Part B: Skull Base

    2023  

    Abstract: Objective: The assessment of baseline olfactory function before endoscopic skull base surgery (ESBS) has been relatively limited compared with analysis before functional endoscopic sinus surgery (FESS). Our study addresses this knowledge gap, assessing ... ...

    Abstract Objective: The assessment of baseline olfactory function before endoscopic skull base surgery (ESBS) has been relatively limited compared with analysis before functional endoscopic sinus surgery (FESS). Our study addresses this knowledge gap, assessing preoperative olfactory function in ESBS and FESS and elucidating any differences.
    Study Design: We conducted a retrospective review of patients undergoing anterior ESBS or FESS at a single institution between 2021 and 2022. We included 171 patients and compared their reported and measured preoperative olfactory function using the Sino-Nasal Outcome Test questionnaire and the 40-item University of Pennsylvania Smell Identification Test.
    Results: Of the 171 patients included in this study, 30% of patients underwent ESBS and 70% underwent FESS. Of all patients, only 57% correctly reported their objective preoperative olfactory function. Of the 36 ESBS patients with measured preoperative hyposmia, only 31% correctly reported hyposmia, while 69% incorrectly reported normosmia. This distribution significantly differs ( p  < 0.0001) from the FESS subset (89 patients), with 64% correctly reporting hyposmia and 36% incorrectly reporting normosmia.
    Conclusions: Our analysis demonstrates higher than anticipated underreporting of preoperative hyposmia in patients undergoing ESBS as well as discrepancies between subjective and objective olfactory functions in the FESS population. The results highlight several gaps in knowledge regarding perioperative olfactory function that would be best examined with more thorough pre- and postoperative objective olfactory testing. This analysis demonstrates significant prognostic uncertainty for patients and providers and creates significant medicolegal uncertainty regarding the appropriate attribution of postoperative olfactory loss in cases without objective preoperative testing.
    Schlagwörter endoscopic skull base surgery ; extended endoscopic approach ; functional endoscopic sinus surgery ; olfactory function ; olfactory dysfunction ; olfaction ; hyposmia ; anosmia ; smell loss
    Sprache Englisch
    Erscheinungsdatum 2023-11-08
    Verlag Georg Thieme Verlag KG
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0043-1775851
    Datenquelle Thieme Verlag

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  9. Artikel: Aspiration of Aluminum Beverage Can Tab: Case Report and Literature Review.

    Elghouche, Alhasan N / Lobo, Brian C / Ting, Jonathan Y

    Case reports in otolaryngology

    2017  Band 2017, Seite(n) 1010975

    Abstract: We describe the case of a 16-year-old male who aspirated a beverage can tab resulting in significant functional impairment. Since the introduction of beverage can opening tabs ("pop-tops" or "pull-tabs") nearly 50 years ago, five cases of their ... ...

    Abstract We describe the case of a 16-year-old male who aspirated a beverage can tab resulting in significant functional impairment. Since the introduction of beverage can opening tabs ("pop-tops" or "pull-tabs") nearly 50 years ago, five cases of their aspiration have been reported in the literature and this is the first case to report tracheal lodgment. We describe the clinical course for this patient including the inadequacy of radiographic evaluation and a significant delay in diagnosis. We highlight unique features of small aluminum foreign bodies that require consideration and mention a potential change in epidemiology associated with evolving product design. Our primary objective is increased awareness among otolaryngologists that radiography is unreliable for diagnosis or localization of small aluminum foreign bodies. The patient history must therefore be incorporated with other imaging modalities and/or endoscopic evaluation. Also, given the marked prevalence of aluminum beverage cans, we suspect that the inadvertent aspiration of can tabs is more common than indicated by the paucity of published reports.
    Sprache Englisch
    Erscheinungsdatum 2017-05-28
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2648756-1
    ISSN 2090-6773 ; 2090-6765
    ISSN (online) 2090-6773
    ISSN 2090-6765
    DOI 10.1155/2017/1010975
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Application of Ultrasonic Aspirators in Rhinology and Skull Base Surgery.

    Vernon, Dominic / Lobo, Brian C / Ting, Jonathan Y

    Otolaryngologic clinics of North America

    2017  Band 50, Heft 3, Seite(n) 607–616

    Abstract: Ultrasonic aspirators (UAs) are increasingly being used in rhinology and skull base surgery. The use of ultrasonic vibration for the removal of bony tissue transfers minimal heat to surrounding tissues and is relatively atraumatic to nearby soft tissue ... ...

    Abstract Ultrasonic aspirators (UAs) are increasingly being used in rhinology and skull base surgery. The use of ultrasonic vibration for the removal of bony tissue transfers minimal heat to surrounding tissues and is relatively atraumatic to nearby soft tissue structures. This article details the development and application of this technology in septoturbinoplasty, endoscopic dacryocystorhinostomy (DCR), and skull base surgery. The benefits and limitations of UAs compared with conventionally powered instruments are discussed.
    Sprache Englisch
    Erscheinungsdatum 2017-06
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 417489-6
    ISSN 1557-8259 ; 0030-6665
    ISSN (online) 1557-8259
    ISSN 0030-6665
    DOI 10.1016/j.otc.2017.01.011
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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