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  1. Book ; Online ; E-Book: Allergens and allergen immunotherapy

    Lockey, Richard F. / Ledford, Dennis K.

    subcutaneous, sublingual and oral

    2020  

    Author's details edited by Richard F. Lockey, Dennis K. Ledford
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xix, 577 Seiten), Illustrationen
    Edition Sixth edition
    Publisher CRC Press, Taylor & Francis Group
    Publishing place Boca Raton
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020405060
    ISBN 978-1-351-20898-7 ; 9780815382218 ; 1-351-20898-5 ; 0815382219
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Allergens and allergen immunotherapy

    Lockey, Richard F. / Ledford, Dennis K.

    subcuntaneous, sublingual and oral

    2014  

    Author's details ed. by Richard F. Lockey ; Dennis K. Ledford
    Keywords Hypersensitivity / therapy ; Immunotherapy ; Allergens / therapeutic use ; Allergens / immunology
    Language English
    Size XX, 524 S. : zahlr. Ill., graph. Darst.
    Edition 5. ed.
    Publisher CRC Press
    Publishing place Boca Raton u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT017788768
    ISBN 978-1-84214-573-9 ; 1-84214-573-8
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Asthma

    Ledford, Dennis K. / Lockey, Richard F.

    comorbidities, coexisting conditions, and differential diagnosis

    2014  

    Institution World Allergy Organization
    Author's details ed. by Richard F. Lockey, Dennis K. Ledford. WAO, World Allergy Organization
    Keywords Asthma / complications ; Asthma / diagnosis ; Respiratory Tract Diseases / complications ; Respiratory Tract Diseases / diagnosis ; Diagnosis, Differential
    Language English
    Size XX, 481 S. : Ill, graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT018252979
    ISBN 978-0-19-991806-5 ; 0-19-991806-6
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Allergens and allergen immunotherapy

    Lockey, Richard F.

    (Clinical allergy and immunology ; 21)

    2008  

    Author's details ed. by Richard F. Lockey
    Series title Clinical allergy and immunology ; 21
    Collection
    Keywords Hypersensitivity / therapy ; Immunotherapy ; Allergens / therapeutic use ; Allergens / immunology
    Language English
    Size XVI, 550 S., [2] Bl. : Ill., graph. Darst.
    Edition 4. ed.
    Publisher Informa Healthcare
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT015589865
    ISBN 978-1-4200-6197-0 ; 1-4200-6197-6
    Database Catalogue ZB MED Medicine, Health

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  5. Book: Allergens and allergen immunotherapy

    Lockey, Richard F.

    (Clinical allergy and immunology ; 18)

    2004  

    Author's details ed. by Richard F. Lockey
    Series title Clinical allergy and immunology ; 18
    Collection
    Keywords Hypersensitivity / therapy ; Immunotherapy ; Allergens / therapeutic use ; Allergens / immunology
    Language English
    Size XVII, 808 S. : Ill., graph. Darst.
    Edition 3. ed., rev. and expanded
    Publisher Dekker
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    New title 2. Aufl. u.d.T. Allergens and allergen immunotherapy
    HBZ-ID HT013921872
    ISBN 0824754069 ; 9780824754068
    Database Catalogue ZB MED Medicine, Health

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  6. Book: Allergens and allergen immunotherapy

    Lockey, Richard F.

    (Clinical allergy and immunology ; 12)

    1998  

    Author's details ed. by Richard F. Lockey
    Series title Clinical allergy and immunology ; 12
    Collection
    Keywords Hypersensitivity / therapy ; Immunotherapy ; Allergen ; Immuntherapie ; Allergenextrakt ; Desensibilisierung
    Subject Hyposensibilisierung ; Spezifische Hyposensibilisierung ; Spezifische Immuntherapie ; SIT ; Immunotherapie
    Language English
    Size XIX, 609 S. : Ill., graph. Darst.
    Edition 2. ed., rev. and exp.
    Publisher Dekker
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    New title 3. Aufl. u.d.T. Allergen immunotherapy
    HBZ-ID HT009418446
    ISBN 0824701889 ; 9780824701888
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Pyroptosis Inhibition in Disease Treatment: Opportunities and Challenges.

    Bandharam, Navya / Lockey, Richard F / Kolliputi, Narasaiah

    Cell biochemistry and biophysics

    2023  Volume 81, Issue 4, Page(s) 615–619

    Abstract: Programmed cell death (PCD) is at the center of immune responses, with different types of PCD occurring based on bodily conditions at a given moment. The main three types of PCD include pyroptosis, necroptosis, and apoptosis. Both pyroptosis and ... ...

    Abstract Programmed cell death (PCD) is at the center of immune responses, with different types of PCD occurring based on bodily conditions at a given moment. The main three types of PCD include pyroptosis, necroptosis, and apoptosis. Both pyroptosis and necroptosis induce an inflammatory response while apoptosis avoids eliciting an inflammatory reaction. Recently, pyroptosis has come to the forefront of immunology research due to tremendous potential that has been revealed surrounding the regulators of pyroptosis. In addition to previously known regulators of pyroptosis (ZBP1 and NLRP3 genes), a family of proteins called Gasdermin has been discovered. Specifically, Gasdermin D (GSDMD), when cleaved, participates in the onset of pyroptosis of inflammatory diseases. The N-terminal cleaved portion of the molecule causes cellular membrane openings releasing interleukin-18 and IL-1β, inducing pyroptosis. It is hypothesized that the inhibition of GSDMD using drugs such as Dimethyl Fumarate (DMF) and Disulfiram may halt the progression of certain inflammatory diseases including Multiple Sclerosis (MS), autoimmune encephalitis etc. While there is not yet a concrete treatment for pyroptic cell death in inflammatory disease using GSDMD inhibition, there is ample evidence to suggest that there may be success in future studies and therapeutic applications of GSDMD.
    MeSH term(s) Humans ; Pyroptosis ; Intracellular Signaling Peptides and Proteins/metabolism ; Gasdermins ; Apoptosis ; Inflammation/drug therapy ; Inflammasomes/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism
    Chemical Substances Intracellular Signaling Peptides and Proteins ; Gasdermins ; Inflammasomes ; NLR Family, Pyrin Domain-Containing 3 Protein
    Language English
    Publishing date 2023-10-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1357904-6
    ISSN 1559-0283 ; 1085-9195
    ISSN (online) 1559-0283
    ISSN 1085-9195
    DOI 10.1007/s12013-023-01181-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Asthma and carotid artery plaques.

    Cardet, Juan Carlos / Weare-Regales, Natalia / Lockey, Richard F

    The Journal of allergy and clinical immunology

    2023  Volume 151, Issue 5, Page(s) 1257–1258

    MeSH term(s) Humans ; Carotid Stenosis ; Inflammation ; Risk Factors ; Asthma
    Language English
    Publishing date 2023-03-02
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2023.02.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Asthma and Comorbid Conditions.

    Fuhlbrigge, Anne / Lockey, Richard F

    The journal of allergy and clinical immunology. In practice

    2021  Volume 9, Issue 11, Page(s) 3909–3910

    MeSH term(s) Asthma/epidemiology ; Comorbidity ; Humans
    Language English
    Publishing date 2021-11-06
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2021.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A 48-year-old female with perioperative anaphylaxis.

    Kolinsky, Nicholas C / Lockey, Richard F

    Allergy and asthma proceedings

    2021  Volume 42, Issue 3, Page(s) 257–259

    Abstract: Identifying the culprit medication in cases of perioperative anaphylaxis can be extremely challenging. A detailed and accurate history, coupled with the appropriate testing, plays a key role in discovering the etiology of perioperative anaphylaxis. We ... ...

    Abstract Identifying the culprit medication in cases of perioperative anaphylaxis can be extremely challenging. A detailed and accurate history, coupled with the appropriate testing, plays a key role in discovering the etiology of perioperative anaphylaxis. We present the case of a 48-year-old woman with a cranial meningioma who was scheduled for surgery. Chlorhexidine, midazolam, lidocaine, propofol, fentanyl, rocuronium, and furosemide were administered during the perioperative period. She developed hypotension, urticaria, bronchospasm, and other symptoms of anaphylaxis soon after general anesthesia. The serum tryptase level obtained during anaphylaxis was 119 ng/mL (normal, <11.4 ng/mL). Epinephrine was administered, and the surgery was canceled, with no cause identified. For the next surgical attempt, she was pretreated with diphenhydramine and ranitidine, and the neuromuscular blocker was withheld. Again, she developed hypotension consistent with anaphylaxis, and epinephrine was administered. She was referred for consultation. A detailed and accurate history was obtained. The baseline serum tryptase level was 6.4 ng/mL. Skin-prick puncture tests were completed, and a diagnosis was made. The surgical team was instructed to avoid the culprit medication, and the cranial surgery was successful. Although difficult, cases of perioperative anaphylaxis can be solved with a detailed history, keen detective work, and appropriate testing.
    MeSH term(s) Anaphylaxis/diagnosis ; Anaphylaxis/etiology ; Epinephrine ; Female ; Humans ; Hypotension ; Middle Aged ; Skin Tests ; Tryptases
    Chemical Substances Tryptases (EC 3.4.21.59) ; Epinephrine (YKH834O4BH)
    Language English
    Publishing date 2021-03-22
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1312445-6
    ISSN 1539-6304 ; 1088-5412
    ISSN (online) 1539-6304
    ISSN 1088-5412
    DOI 10.2500/aap.2021.42.200060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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