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Article ; Online: Cerebral Herniation from Hyperammonemic Cerebral Edema: A Potentially Reversible Neurological Emergency.

Loggini, Andrea / Martinez, Raisa C / Kramer, Christopher L

2018 Volume 30, Issue 3, Page(s) 681–685

MeSH term(s)	Brain Edema/diagnosis ; Brain Edema/etiology ; Brain Edema/therapy ; Female ; Humans ; Hyperammonemia/complications ; Hyperammonemia/diagnosis ; Hyperammonemia/therapy ; Intracranial Hypertension/diagnosis ; Intracranial Hypertension/therapy ; Middle Aged ; Tomography, X-Ray Computed
Language	English
Publishing date	2018-10-17
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2381896-7
ISSN	1556-0961 ; 1541-6933
ISSN (online)	1556-0961
ISSN	1541-6933
DOI	10.1007/s12028-018-0578-9
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Article: Case Report: Management of Traumatic Carotid-Cavernous Fistulas in the Acute Setting of Penetrating Brain Injury.

Loggini, Andrea / Kass-Hout, Tareq / Awad, Issam A / El Ammar, Faten / Kramer, Christopher L / Goldenberg, Fernando D / Lazaridis, Christos / Mansour, Ali

Frontiers in neurology

2022 Volume 12, Page(s) 715955

Abstract: Traumatic carotid-cavernous fistulas (tCCFs) after penetrating brain injury (PBI) have been uncommonly described in the literature with little guidance on optimal treatment. In this case series, we present two patients with PBI secondary to gunshot ... ...

Abstract	Traumatic carotid-cavernous fistulas (tCCFs) after penetrating brain injury (PBI) have been uncommonly described in the literature with little guidance on optimal treatment. In this case series, we present two patients with PBI secondary to gunshot wounds to the head who acutely developed tCCFs, and we review the lead-up to diagnosis in addition to the treatment of this condition. We highlight the importance of early cerebrovascular imaging as the clinical manifestations may be limited by poor neurological status and possibly concomitant injury. Definitive treatment should be attempted as soon as possible with embolization of the fistula, flow diversion via stenting of the fistula site, and, finally, vessel sacrifice as possible therapeutic options.
Language	English
Publishing date	2022-02-11
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2564214-5
ISSN	1664-2295
ISSN	1664-2295
DOI	10.3389/fneur.2021.715955
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Article ; Online: Frequency, Risk Factors, and Outcomes of Unplanned Readmission to the Neurological Intensive Care Unit after Spontaneous Intracerebral Hemorrhage.

Tangonan, Ruth / Alvarado-Dyer, Ronald / Loggini, Andrea / Ammar, Faten El / Kumbhani, Ruchit / Lazaridis, Christos / Kramer, Christopher / Goldenberg, Fernando D / Mansour, Ali

Neurocritical care

2022 Volume 37, Issue 2, Page(s) 390–398

Abstract: Background: Unplanned readmission to the neurological intensive care unit (ICU) is an underinvestigated topic in patients admitted after spontaneous intracerebral hemorrhage (ICH). The purpose of this study is to investigate the frequency, clinical risk ...

Abstract	Background: Unplanned readmission to the neurological intensive care unit (ICU) is an underinvestigated topic in patients admitted after spontaneous intracerebral hemorrhage (ICH). The purpose of this study is to investigate the frequency, clinical risk factors, and outcome of bounce back to the neurological ICU in a cohort of patients admitted after ICH. Methods: This is a retrospective observational study inspecting bounce back to the neurological ICU in patients admitted with spontaneous ICH over an 8-year period. For each patient, demographics, medical history, clinical presentation, length of ICU stay, unplanned readmission to neurological ICU, cause of readmission, and mortality were reviewed. Bounce back to the neurological ICU was defined as an unplanned readmission to the neurological ICU from a general floor service during the same hospitalization. A multivariable analysis was used to define independent variables associated with bounce back to the neurological ICU as well as association between bounce back to the neurological ICU and mortality. The significance level was set at p < 0.05. Results: A total of 221 patients were included. Among those, 20 (9%) had a bounce back to the neurological ICU. Respiratory complications (n = 11) was the most common reason for bounce back to the neurological ICU, followed by neurological (n = 5) and cardiological (n = 4) complications. In a multivariable logistic regression, location of hemorrhage in the basal ganglia (odds ratio [OR]: 3.0, 95% confidence interval [CI]: 1.0-8.9, p = 0.03) and dysphagia at the time of transfer (OR: 3.9, 95% CI: 1.0-15.4, p = 0.04) were significantly associated with bounce back to the neurological ICU. After we controlled for ICH score, readmission to the ICU was also independently associated with higher mortality (OR: 14.1, 95% CI: 2.8-71.7, p < 0.01). Conclusions: Bounce back to the neurological ICU is not an infrequent complication in patients with spontaneous ICH and is associated with higher hospital length of stay and mortality. We identified relevant and potentially modifiable risk factors associated with bounce back to the neurological ICU. Future prospective studies are necessary to develop patient-centered strategies that may improve transition from the neurological ICU to the general floor.
MeSH term(s)	Cerebral Hemorrhage/epidemiology ; Cerebral Hemorrhage/therapy ; Humans ; Intensive Care Units ; Patient Readmission ; Prospective Studies ; Retrospective Studies ; Risk Factors
Language	English
Publishing date	2022-01-24
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	2381896-7
ISSN	1556-0961 ; 1541-6933
ISSN (online)	1556-0961
ISSN	1541-6933
DOI	10.1007/s12028-021-01415-w
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Article ; Online: Association between electrolyte levels at presentation and hematoma expansion and outcome in spontaneous intracerebral hemorrhage: A systematic review.

Loggini, Andrea / El Ammar, Faten / Mansour, Ali / Kramer, Christopher L / Goldenberg, Fernando D / Lazaridis, Christos

Journal of critical care

2020 Volume 61, Page(s) 177–185

Abstract: Purpose: To assess the association between specific electrolyte levels (sodium, potassium, calcium, magnesium, and phosphorus) on presentation and hematoma expansion (HE) and outcome in intracerebral hemorrhage (ICH).: Methods: This review was ... ...

Abstract	Purpose: To assess the association between specific electrolyte levels (sodium, potassium, calcium, magnesium, and phosphorus) on presentation and hematoma expansion (HE) and outcome in intracerebral hemorrhage (ICH). Methods: This review was conducted in accordance with the PRISMA statement recommendations. Three databases were searched (Pubmed, Scopus, and Cochrane). Risk of bias was computed using the Newcastle-Ottawa Scale tool. Results: 18 full-text articles were included in this systematic review including 10,385 ICH patients. Hypocalcemia was associated with worse short-term outcome in four studies, and two other studies were neutral. All studies investigating HE in hypocalcemia (n = 5) reported an association between low calcium level and HE. Hyponatremia (Na < 135 mEq/L) was shown to correlate with worse short-term outcome in two studies, and worse long-term outcome in one. There was one report showing no association between sodium level and HE. Hypomagnesemia was shown to be associated with worse short-term outcome in one study, while other reports were neutral. Studies evaluating hypophosphatemia or hypokalemia in ICH were limited, with no demonstrable significant effect on outcome. Conclusion: This review suggests a significant association between hypocalcemia, hyponatremia and, of lesser degree, hypomagnesemia on admission and HE or worse outcome in ICH.
MeSH term(s)	Cerebral Hemorrhage ; Electrolytes ; Hematoma ; Humans ; Hypocalcemia ; Sodium
Chemical Substances	Electrolytes ; Sodium (9NEZ333N27)
Language	English
Publishing date	2020-11-03
Publishing country	United States
Document type	Journal Article ; Review ; Systematic Review
ZDB-ID	632818-0
ISSN	1557-8615 ; 0883-9441
ISSN (online)	1557-8615
ISSN	0883-9441
DOI	10.1016/j.jcrc.2020.10.029
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Article ; Online: Machine Learning for Early Detection of Hypoxic-Ischemic Brain Injury After Cardiac Arrest.

Mansour, Ali / Fuhrman, Jordan D / Ammar, Faten El / Loggini, Andrea / Davis, Jared / Lazaridis, Christos / Kramer, Christopher / Goldenberg, Fernando D / Giger, Maryellen L

Neurocritical care

2021 Volume 36, Issue 3, Page(s) 974–982

Abstract: Background: Establishing whether a patient who survived a cardiac arrest has suffered hypoxic-ischemic brain injury (HIBI) shortly after return of spontaneous circulation (ROSC) can be of paramount importance for informing families and identifying ... ...

Abstract	Background: Establishing whether a patient who survived a cardiac arrest has suffered hypoxic-ischemic brain injury (HIBI) shortly after return of spontaneous circulation (ROSC) can be of paramount importance for informing families and identifying patients who may benefit the most from neuroprotective therapies. We hypothesize that using deep transfer learning on normal-appearing findings on head computed tomography (HCT) scans performed after ROSC would allow us to identify early evidence of HIBI. Methods: We analyzed 54 adult comatose survivors of cardiac arrest for whom both an initial HCT scan, done early after ROSC, and a follow-up HCT scan were available. The initial HCT scan of each included patient was read as normal by a board-certified neuroradiologist. Deep transfer learning was used to evaluate the initial HCT scan and predict progression of HIBI on the follow-up HCT scan. A naive set of 16 additional patients were used for external validation of the model. Results: The median age (interquartile range) of our cohort was 61 (16) years, and 25 (46%) patients were female. Although findings of all initial HCT scans appeared normal, follow-up HCT scans showed signs of HIBI in 29 (54%) patients (computed tomography progression). Evaluating the first HCT scan with deep transfer learning accurately predicted progression to HIBI. The deep learning score was the most significant predictor of progression (area under the receiver operating characteristic curve = 0.96 [95% confidence interval 0.91-1.00]), with a deep learning score of 0.494 having a sensitivity of 1.00, specificity of 0.88, accuracy of 0.94, and positive predictive value of 0.91. An additional assessment of an independent test set confirmed high performance (area under the receiver operating characteristic curve = 0.90 [95% confidence interval 0.74-1.00]). Conclusions: Deep transfer learning used to evaluate normal-appearing findings on HCT scans obtained early after ROSC in comatose survivors of cardiac arrest accurately identifies patients who progress to show radiographic evidence of HIBI on follow-up HCT scans.
MeSH term(s)	Adult ; Brain Injuries ; Coma/diagnostic imaging ; Coma/etiology ; Female ; Humans ; Hypoxia-Ischemia, Brain/diagnostic imaging ; Hypoxia-Ischemia, Brain/etiology ; Machine Learning ; Male ; Middle Aged ; Out-of-Hospital Cardiac Arrest/therapy ; Retrospective Studies
Language	English
Publishing date	2021-12-06
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2381896-7
ISSN	1556-0961 ; 1541-6933
ISSN (online)	1556-0961
ISSN	1541-6933
DOI	10.1007/s12028-021-01405-y
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Article ; Online: Effect of desmopressin on hematoma expansion in antiplatelet-associated intracerebral hemorrhage: A systematic review and meta-analysis.

Loggini, Andrea / El Ammar, Faten / Darzi, Andrea J / Mansour, Ali / Kramer, Christopher L / Goldenberg, Fernando D / Lazaridis, Christos

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

2021 Volume 86, Page(s) 116–121

Abstract: The purpose of this study was to perform a systematic review and meta-analysis on the effect of desmopressin on hematoma expansion (HE) in antiplatelet-associated intracerebral hemorrhage (AA-ICH). Secondary outcomes examined were the rate of thrombotic ... ...

Abstract	The purpose of this study was to perform a systematic review and meta-analysis on the effect of desmopressin on hematoma expansion (HE) in antiplatelet-associated intracerebral hemorrhage (AA-ICH). Secondary outcomes examined were the rate of thrombotic complications and neurologic outcome. Three databases were searched (Pubmed, Scopus, and Cochrane) for randomized clinical trials and controlled studies comparing desmopressin versus controls in adult patients with AA-ICH. The Mantel-Haenszel method was applied to calculate an overall effect estimate for each outcome by combining stratum-specific risk ratio (RR). Risk of bias was computed using the Newcastle-Ottawa Scale. The protocol was registered in PROSPERO (42020190234). Three retrospective controlled studies involving 263 patients were included in the meta-analysis. Compared to controls, desmopressin was associated with a non-significant reduction in HE (19.1% vs. 30%; RR:0.61; 95%CI, 0.27-1.39; P = 0.24), a similar rate of thrombotic events (5.5% vs. 9.9%; RR:0.47; 95%CI, 0.17-1.31; P = 0.15), and significantly worse neurologic outcome (mRS ≥ 4) (66.3% vs. 50%; RR:1.36; 95%CI, 1.08-1.7; P = 0.008). Qualitative analysis of included studies for each outcome revealed low to moderate risk of bias. The available literature does not support the routine use of desmopressin in the setting of AA-ICH. Until larger prospective trials are performed, the administration of desmopressin should be judiciously considered on a case-by-case basis.
MeSH term(s)	Cerebral Hemorrhage/chemically induced ; Cerebral Hemorrhage/diagnosis ; Cerebral Hemorrhage/drug therapy ; Deamino Arginine Vasopressin/therapeutic use ; Hematoma/diagnosis ; Hematoma/drug therapy ; Hemostatics/therapeutic use ; Humans ; Platelet Aggregation Inhibitors/adverse effects ; Prospective Studies ; Randomized Controlled Trials as Topic/methods ; Retrospective Studies ; Treatment Outcome
Chemical Substances	Hemostatics ; Platelet Aggregation Inhibitors ; Deamino Arginine Vasopressin (ENR1LLB0FP)
Language	English
Publishing date	2021-02-03
Publishing country	Scotland
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	1193674-5
ISSN	1532-2653 ; 0967-5868
ISSN (online)	1532-2653
ISSN	0967-5868
DOI	10.1016/j.jocn.2021.01.017
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Article ; Online: Civilian Firearm-Inflicted Brain Injury: Coagulopathy, Vascular Injuries, and Triage.

Lazaridis, Christos / Mansour, Ali / Alvarado-Dyer, Ronald / Tangonan, Ruth / Loggini, Andrea / Kramer, Christopher / Goldenberg, Fernando D

Current neurology and neuroscience reports

2021 Volume 21, Issue 9, Page(s) 47

Abstract: Purpose of review: Civilian firearm-inflicted penetrating brain injury (PBI) carries high morbidity and mortality. Concurrently, the evidence base guiding management decisions remains limited. Faced with large volume of PBI patients, we have made ... ...

Abstract	Purpose of review: Civilian firearm-inflicted penetrating brain injury (PBI) carries high morbidity and mortality. Concurrently, the evidence base guiding management decisions remains limited. Faced with large volume of PBI patients, we have made observations in relation to coagulopathy and cerebrovascular injuries. We here review this literature in addition to the question about early prognostication as it may inform neurosurgical decision-making. Recent findings: The triad of coagulopathy, low motor score, and radiographic compression of basal cisterns comprises a phenotype of injury with exceedingly high mortality. PBI leads to high rates of cerebral arterial and venous injuries, and projectile trajectory is emerging as an independent predictor of outcome. The combination of coagulopathy with cerebrovascular injury creates a specific endophenotype. The nature and role of coagulopathy remain to be deciphered, and consideration to the use of tranexamic acid should be given. Prospective controlled trials are needed to create clinical evidence free of patient selection bias.
MeSH term(s)	Brain Injuries ; Head Injuries, Penetrating/complications ; Head Injuries, Penetrating/diagnostic imaging ; Head Injuries, Penetrating/epidemiology ; Humans ; Prospective Studies ; Triage ; Vascular System Injuries
Language	English
Publishing date	2021-07-10
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2057363-7
ISSN	1534-6293 ; 1528-4042
ISSN (online)	1534-6293
ISSN	1528-4042
DOI	10.1007/s11910-021-01131-0
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Article ; Online: Inversion of T Waves on Admission is Associated with Mortality in Spontaneous Intracerebral Hemorrhage.

Loggini, Andrea / Mansour, Ali / El Ammar, Faten / Tangonan, Ruth / Kramer, Christopher L / Goldenberg, Fernando D / Lazaridis, Christos

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

2021 Volume 30, Issue 6, Page(s) 105776

Abstract: Introduction: Cardiac dysfunction directly caused by spontaneous intracerebral hemorrhage (ICH) is a poorly understood phenomenon, and its impact on outcome is still uncertain. The aim of this study is to investigate the relationship between ... ...

Abstract	Introduction: Cardiac dysfunction directly caused by spontaneous intracerebral hemorrhage (ICH) is a poorly understood phenomenon, and its impact on outcome is still uncertain. The aim of this study is to investigate the relationship between electrocardiographic (EKG) abnormalities and mortality in ICH. Methods: This is a retrospective study analyzing EKG patterns on admission in patients admitted with ICH at a tertiary care center over an eight-year period. For each patient, demographics, medical history, clinical presentation, EKG on admission and during hospitalization, and head CT at presentation were reviewed. Mortality was noted. Results: A total of 301 ICH patients were included in the study. The most prevalent EKG abnormalities were QTc prolongation in 56% of patients (n = 168) followed by inversion of T waves (TWI) in 37% of patients (n = 110). QTc prolongation was associated with ganglionic location (p = 0.03) and intraventricular hemorrhage (IVH) (p = 0.01), TWIs were associated with ganglionic location (p = 0.02), and PR prolongation was associated with IVH (p = 0.01), while QRS prolongation was associated with lobar location (p < 0.01). Volume of ICH, hemispheric laterality, and involvement of insular cortex were not correlated with specific EKG patterns. In a logistic regression model, after correcting for ICH severity and prior cardiac history, presence of TWI was independently associated with mortality (OR: 3.04, CI:1.6-5.8, p < 0.01). Adding TWI to ICH score improved its prognostic accuracy (AUC 0.81, p = 0.04). Disappearance of TWI during hospitalization did not translate into improvement of survival (p = 0.5). Conclusion: Presence of TWI on admission is an independent and unmodifiable factor associated with mortality in ICH. Further research is needed to elucidate the pathophysiologic mechanisms underlying electrocardiographic changes after primary intracerebral hemorrhage.
MeSH term(s)	Action Potentials ; Aged ; Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/mortality ; Arrhythmias, Cardiac/physiopathology ; Cerebral Hemorrhage/diagnosis ; Cerebral Hemorrhage/mortality ; Cerebral Hemorrhage/physiopathology ; Electrocardiography ; Female ; Heart Conduction System/physiopathology ; Heart Rate ; Humans ; Male ; Middle Aged ; Patient Admission ; Predictive Value of Tests ; Prevalence ; Prognosis ; Retrospective Studies ; Risk Assessment ; Risk Factors
Language	English
Publishing date	2021-04-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	1131675-5
ISSN	1532-8511 ; 1052-3057
ISSN (online)	1532-8511
ISSN	1052-3057
DOI	10.1016/j.jstrokecerebrovasdis.2021.105776
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Article ; Online: The role of amantadine in cognitive recovery early after traumatic brain injury: A systematic review.

Loggini, Andrea / Tangonan, Ruth / El Ammar, Faten / Mansour, Ali / Goldenberg, Fernando D / Kramer, Christopher L / Lazaridis, Christos

Clinical neurology and neurosurgery

2020 Volume 194, Page(s) 105815

Abstract: We conducted an updated systematic review on the safety and efficacy of amantadine in cognitive recovery after traumatic brain injury (TBI), in order to determine if the current literature justifies its use in this clinical condition. A comprehensive ... ...

Abstract	We conducted an updated systematic review on the safety and efficacy of amantadine in cognitive recovery after traumatic brain injury (TBI), in order to determine if the current literature justifies its use in this clinical condition. A comprehensive search strategy was applied to three databases (PubMed, Scopus, and Cochrane). Only randomized clinical trials (RCTs) that compared the effect of amantadine and placebo in adults within 3 months of TBI were included in the review. Study characteristics, outcomes, and methodological quality were synthesized. This systematic review was conducted and presented in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). A quantitative synthesis (meta-analysis) was not feasible due to the large heterogeneity of studies identified. Three parallel RCTs and one cross-over RCT, with a total of 325 patients were included. All of the studies evaluated only severe TBI in adults. Amantadine was found to be well tolerated across the studies. Two RCTs reported improvement in the intermediate-term cognitive recovery (four to six weeks after end of treatment), using DRS (in both studies) and MMSE, GOS, and FIM-Cog (in one study). The effect of amantadine on the short-term (seven days to discharge) and long-term (six months from the injury) cognitive outcome was found not superior to placebo in two RCTs. The rate of severe adverse events was found to be consistently very low across the studies (the incidence of seizures, elevation in liver enzymes and cardiac death was 0.7 %, 1.9 %, and 0.3 %, respectively). In conclusion, amantadine seems to be well tolerated and might hasten the rate of cognitive recovery in the intermediate-term outcome. However, the long-term effect of amantadine in cognitive recovery is not well defined and further large randomized clinical trials in refined subgroups of patients are needed to better define its application.
MeSH term(s)	Amantadine/therapeutic use ; Brain Injuries, Traumatic/complications ; Brain Injuries, Traumatic/drug therapy ; Brain Injuries, Traumatic/psychology ; Cognition Disorders/drug therapy ; Cognition Disorders/etiology ; Cognition Disorders/psychology ; Humans ; Nootropic Agents/therapeutic use ; Randomized Controlled Trials as Topic ; Recovery of Function
Chemical Substances	Nootropic Agents ; Amantadine (BF4C9Z1J53)
Language	English
Publishing date	2020-03-21
Publishing country	Netherlands
Document type	Journal Article ; Systematic Review
ZDB-ID	193107-6
ISSN	1872-6968 ; 0303-8467
ISSN (online)	1872-6968
ISSN	0303-8467
DOI	10.1016/j.clineuro.2020.105815
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Article ; Online: Management of civilians with penetrating brain injury: A systematic review.

Loggini, Andrea / Vasenina, Valentina I / Mansour, Ali / Das, Paramita / Horowitz, Peleg M / Goldenberg, Fernando D / Kramer, Christopher / Lazaridis, Christos

Journal of critical care

2020 Volume 56, Page(s) 159–166

Abstract: Purpose: There has been a dramatic increase in penetrating gunshot-inflicted civilian penetrating brain injuries (cvPBI). We undertook a systematic review with exclusive focus on the management of cvPBI.: Methods: We explored: (1) cervical spine ... ...

Abstract	Purpose: There has been a dramatic increase in penetrating gunshot-inflicted civilian penetrating brain injuries (cvPBI). We undertook a systematic review with exclusive focus on the management of cvPBI. Methods: We explored: (1) cervical spine immobilization, (2) seizure incidence and prophylaxis, (3) infection incidence and antibiotic prophylaxis, (4) coagulopathy (5) vascular complications, and (6) surgical management. We searched PubMed, EMBASE, and Cochrane (1985-2019). The PRISMA guidelines were followed. The Newcastle-Ottawa Scale was employed for qualitative assessment; risk of bias was evaluated based upon the RTI item bank. The full protocol was registered to PROSPERO (CRD42019118877). Results: The literature is scant, and of overall low quality and high risk of bias. Incidence of c-spine injury with no direct trauma is low; incidence of seizures does not appear to be different from non-penetrating mechanisms; there is no robust data for prophylactic antibiotics; coagulopathy is prevalent and has been independently associated with outcome; there is a high incidence of vascular injuries with traumatic intracranial aneurysms the most common sequelae; neurosurgical decision-making appears largely influenced by operator's assessment of salvageability. Surgery has been associated with decreased mortality. Conclusions: Limited amount of published work is clinically meaningful; this systematic review identified key knowledge gaps.
MeSH term(s)	Antibiotic Prophylaxis ; Craniocerebral Trauma/etiology ; Craniocerebral Trauma/surgery ; Head Injuries, Penetrating/complications ; Head Injuries, Penetrating/surgery ; Hematologic Diseases/complications ; Humans ; Incidence ; Intracranial Aneurysm ; Neurosurgical Procedures ; Risk Assessment ; Seizures/prevention & control ; Spinal Injuries/complications ; Treatment Outcome ; Vascular Diseases/complications ; Wounds, Gunshot
Language	English
Publishing date	2020-01-02
Publishing country	United States
Document type	Journal Article ; Systematic Review
ZDB-ID	632818-0
ISSN	1557-8615 ; 0883-9441
ISSN (online)	1557-8615
ISSN	0883-9441
DOI	10.1016/j.jcrc.2019.12.026
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Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito