LIVIVO - Search results -

Search results

Result 1 - 10 of total 116

Search options

Article: Whole transcriptome sequence data of 5-FU sensitive and 5-FU resistant tumors generated in a mouse model of de novo carcinogenesis.

Iacovides, Demetris / Loizides, Charalambos / Mitsis, Georgios / Strati, Katerina

2018 Volume 20, Page(s) 1602–1606

Abstract: We have performed whole transcriptome sequencing of 5-FU resistant and 5-FU sensitive tumors generated in a mouse model of de novo carcinogenesis that closely recapitulates tumor initiation, progression and maintenance in vivo. Tumors were generated ... ...

Abstract	We have performed whole transcriptome sequencing of 5-FU resistant and 5-FU sensitive tumors generated in a mouse model of de novo carcinogenesis that closely recapitulates tumor initiation, progression and maintenance in vivo. Tumors were generated using the DMBA/TPA model of chemically induced carcinogenesis [1], tumor-bearing mice were subsequently treated with 5-FU, and tumor growth as well as response to treatment was monitored by measuring tumor volume twice a week. Based on these measurements, we selected two 5-FU resistant and two 5-FU sensitive tumors and performed whole transcriptome sequencing and in order to identify differentially expressed transcripts between the two sets. Data obtained is deposited and available through NCBI SRA (reference number SRP155180 - https://www.ncbi.nlm.nih.gov/sra/?term=SRP155180).
Keywords	covid19
Language	English
Publishing date	2018-09-07
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2786545-9
ISSN	2352-3409
ISSN	2352-3409
DOI	10.1016/j.dib.2018.08.209
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: EORTC-SPECTA Arcagen study, comprehensive genomic profiling and treatment adaptation of rare thoracic cancers.

Tagliamento, Marco / Morfouace, Marie / Loizides, Charalambos / Oliveira, Julio / Greillier, Laurent / Raimbourg, Judith / Toffart, Anne-Claire / Chatellier, Thierry / Cloarec, Nicolas / Sullivan, Ivana / Brasiuniene, Birute / Duruisseaux, Michael / Oselin, Kersti / Robert, Marie-Sophie / Fernandes, Carolina / Poncin, Arnaud / Blay, Jean-Yves / Besse, Benjamin / Girard, Nicolas

NPJ precision oncology

2024 Volume 8, Issue 1, Page(s) 37

Abstract: Arcagen (NCT02834884) is a European prospective study aiming at defining the molecular landscape of rare cancers for treatment guidance. We present data from the cohort of rare thoracic tumors. Patients with advanced pleural mesothelioma (PM) or thymic ... ...

Abstract	Arcagen (NCT02834884) is a European prospective study aiming at defining the molecular landscape of rare cancers for treatment guidance. We present data from the cohort of rare thoracic tumors. Patients with advanced pleural mesothelioma (PM) or thymic epithelial tumors (TET) underwent genomic profiling with large targeted assay [>300 genes, tumor mutational burden (TMB), microsatellite instability (MSI) status] on formalin-fixed paraffin-embedded (FFPE) or plasma samples. EORTC molecular tumor board (MTB) advised for biomarker-guided treatments. 102 patients recruited from 8 countries between July 2019 and May 2022 were evaluable: 56 with PM, 46 with TET (23 thymomas, 23 thymic carcinomas). Molecular profiling was performed on 70 FFPE samples (42 PM, 28 TET), and 32 cases on ctDNA (14 PM, 18 TET), within a median turnaround time of 8 days from sample reception. We detected relevant molecular alterations in 66 out of 102 patients (65%; 79% PM, 48% TET), 51 of 70 FFPE samples (73%; 90% PM, 46% TET), and 15 of 32 plasma samples (47%; 43% PM, 50% TET). The most frequently altered genes were CDKN2A/B, BAP1, MTAP in PM and TP53, CDKN2A/B, SETD2 in TET. The TMB was low (mean 3.2 Muts/MB), 2 PM had MSI-high status. MTB advised molecular-guided treatment options in 32 situations, for 17 PM and 15 TET patients (75% clinical trial option, 22% off-label drug or compassionate use, 3% early access program). Molecular testing and MTB discussion were feasible for patients with rare thoracic cancers and allowed the broadening of treatment options for 30% of the cases.
Language	English
Publishing date	2024-02-16
Publishing country	England
Document type	Journal Article
ISSN	2397-768X
ISSN	2397-768X
DOI	10.1038/s41698-024-00518-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Acute phase response following pulmonary exposure to soluble and insoluble metal oxide nanomaterials in mice.

Gutierrez, Claudia Torero / Loizides, Charis / Hafez, Iosif / Brostrøm, Anders / Wolff, Henrik / Szarek, Józef / Berthing, Trine / Mortensen, Alicja / Jensen, Keld Alstrup / Roursgaard, Martin / Saber, Anne Thoustrup / Møller, Peter / Biskos, George / Vogel, Ulla

Particle and fibre toxicology

2023 Volume 20, Issue 1, Page(s) 4

Abstract: Background: Acute phase response (APR) is characterized by a change in concentration of different proteins, including C-reactive protein and serum amyloid A (SAA) that can be linked to both exposure to metal oxide nanomaterials and risk of ... ...

Abstract	Background: Acute phase response (APR) is characterized by a change in concentration of different proteins, including C-reactive protein and serum amyloid A (SAA) that can be linked to both exposure to metal oxide nanomaterials and risk of cardiovascular diseases. In this study, we intratracheally exposed mice to ZnO, CuO, Al Results: All nanomaterials induced pulmonary inflammation after 1 day, and exposure to ZnO, CuO, SnO Conclusion: Soluble and insoluble metal oxides induced dose-dependent APR with different time dependency. Neutrophil influx, Saa3 mRNA levels in lung tissue and plasma SAA3 levels correlated across all studied nanomaterials, suggesting that these endpoints can be used as biomarkers of acute phase response and cardiovascular disease risk following exposure to soluble and insoluble particles.
MeSH term(s)	Mice ; Animals ; Acute-Phase Reaction/chemically induced ; Zinc Oxide/toxicity ; Zinc Oxide/metabolism ; Lung/metabolism ; Nanostructures/toxicity ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Chemical Substances	titanium dioxide (15FIX9V2JP) ; Zinc Oxide (SOI2LOH54Z) ; cupric oxide (V1XJQ704R4) ; RNA, Messenger
Language	English
Publishing date	2023-01-17
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2170936-1
ISSN	1743-8977 ; 1743-8977
ISSN (online)	1743-8977
ISSN	1743-8977
DOI	10.1186/s12989-023-00514-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Topical Oxybutynin 10% Gel for the Treatment of Primary Focal Hyperhidrosis: A Randomized Double-blind Placebo-controlled Split Area Study.

Artzi, Ofir / Loizides, Christophoros / Zur, Eyal / Sprecher, Eli

Acta dermato-venereologica

2017 Volume 97, Issue 9, Page(s) 1120–1124

Abstract: Limited efficacy, costs, side-effects and complications are issues of concern for most current therapeutic modalities for focal hyperhidrosis. This study evaluated the efficacy of topical oxybutynin 10% gel in treating 61 patients with primary focal ... ...

Abstract	Limited efficacy, costs, side-effects and complications are issues of concern for most current therapeutic modalities for focal hyperhidrosis. This study evaluated the efficacy of topical oxybutynin 10% gel in treating 61 patients with primary focal hyperhidrosis. The gel was applied to the right or left axilla, palms or soles vs. a placebo compound to the contralateral side for 30 days. A blinded visual grading of the change in starch-iodine tests was performed by 2 non-involved physicians. The Hyperhidrosis Disease Severity Scale (HDSS) and Dermatology Life Quality Index (DLQI) questionnaires were administered before and after treatment. The patients rated their satisfaction with treatment. Fifty-three patients completed the 4-week treatment. Sweat reduction in the drug-treated sweating areas was higher than in the control-treated areas. There was a significant mean improvement in pre- and post-treatment HDSS and DQLI (p = 0.001 for both). Thirty-nine subjects (74%) reported moderate-to-high satisfaction. Twice-daily topical application of oxybutynin 10% gel appears to be an effective, safe and well-tolerated treatment for focal primary hyperhidrosis.
Language	English
Publishing date	2017-10-02
Publishing country	Sweden
Document type	Journal Article
ZDB-ID	80007-7
ISSN	1651-2057 ; 0001-5555
ISSN (online)	1651-2057
ISSN	0001-5555
DOI	10.2340/00015555-2731
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui VI Zs.101: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Genotoxicity in the absence of inflammation after tungsten inhalation in mice.

Sørli, Jorid B / Jensen, Alexander C Ø / Mortensen, Alicja / Szarek, Józef / Chatzigianelli, Eleni / Gutierrez, Claudia A T / Jacobsen, Nicklas R / Poulsen, Sarah S / Hafez, Iosif / Loizides, Charis / Biskos, George / Hougaard, Karin S / Vogel, Ulla / Hadrup, Niels

Environmental toxicology and pharmacology

2023 Volume 98, Page(s) 104074

Abstract: Tungsten is used in several applications and human exposure may occur. To assess its pulmonary toxicity, we exposed male mice to nose-only inhalation of tungsten particles at 9, 23 or 132 mg/ ... ...

Abstract	Tungsten is used in several applications and human exposure may occur. To assess its pulmonary toxicity, we exposed male mice to nose-only inhalation of tungsten particles at 9, 23 or 132 mg/m
MeSH term(s)	Humans ; Mice ; Male ; Animals ; Tungsten/metabolism ; Tungsten/pharmacology ; Reactive Oxygen Species/metabolism ; Semen/metabolism ; DNA Damage ; Inflammation/pathology ; Inhalation Exposure/adverse effects ; Bronchoalveolar Lavage Fluid ; Lung
Chemical Substances	Tungsten (V9306CXO6G) ; Reactive Oxygen Species
Language	English
Publishing date	2023-01-29
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1318302-3
ISSN	1872-7077 ; 1382-6689
ISSN (online)	1872-7077
ISSN	1382-6689
DOI	10.1016/j.etap.2023.104074
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4490: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Comparison of acute phase response in mice after inhalation and intratracheal instillation of molybdenum disulphide and tungsten particles.

Gutierrez, Claudia Torero / Loizides, Charis / Hafez, Iosif / Biskos, George / Loeschner, Katrin / Brostrøm, Anders / Roursgaard, Martin / Saber, Anne Thoustrup / Møller, Peter / Sørli, Jorid Birkelund / Hadrup, Niels / Vogel, Ulla

Basic & clinical pharmacology & toxicology

2023 Volume 133, Issue 3, Page(s) 265–278

Abstract: Inhalation studies are the gold standard for assessing the toxicity of airborne materials. They require considerable time, special equipment, and large amounts of test material. Intratracheal instillation is considered a screening and hazard assessment ... ...

Abstract	Inhalation studies are the gold standard for assessing the toxicity of airborne materials. They require considerable time, special equipment, and large amounts of test material. Intratracheal instillation is considered a screening and hazard assessment tool as it is simple, quick, allows control of the applied dose, and requires less test material. The particle-induced pulmonary inflammation and acute phase response in mice caused by intratracheal instillation or inhalation of molybdenum disulphide or tungsten particles were compared. End points included neutrophil numbers in bronchoalveolar lavage fluid, Saa3 mRNA levels in lung tissue and Saa1 mRNA levels in liver tissue, and SAA3 plasma protein. Acute phase response was used as a biomarker for the risk of cardiovascular disease. Intratracheal instillation of molybdenum disulphide or tungsten particles did not produce pulmonary inflammation, while molybdenum disulphide particles induced pulmonary acute phase response with both exposure methods and systemic acute phase response after intratracheal instillation. Inhalation and intratracheal instillation showed similar dose-response relationships for pulmonary and systemic acute phase response when molybdenum disulphide was expressed as dosed surface area. Both exposure methods showed similar responses for molybdenum disulphide and tungsten, suggesting that intratracheal instillation can be used for screening particle-induced acute phase response and thereby particle-induced cardiovascular disease.
MeSH term(s)	Animals ; Mice ; Tungsten ; Acute-Phase Reaction/chemically induced ; Cardiovascular Diseases ; RNA, Messenger
Chemical Substances	molybdenum disulfide (ZC8B4P503V) ; Tungsten (V9306CXO6G) ; RNA, Messenger
Language	English
Publishing date	2023-07-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2134679-3
ISSN	1742-7843 ; 1742-7835
ISSN (online)	1742-7843
ISSN	1742-7835
DOI	10.1111/bcpt.13915
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uf I Zs.144: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Pulmonary toxicity of molybdenum disulphide after inhalation in mice.

Sørli, Jorid B / Jensen, Alexander C Ø / Mortensen, Alicja / Szarek, Józef / Gutierrez, Claudia A T / Givelet, Lucas / Loeschner, Katrin / Loizides, Charis / Hafez, Iosif / Biskos, George / Vogel, Ulla / Hadrup, Niels

Toxicology

2023 Volume 485, Page(s) 153428

Abstract: Molybdenum disulphide ( ... ...

Abstract	Molybdenum disulphide (MoS
MeSH term(s)	Humans ; Mice ; Animals ; Molybdenum/toxicity ; Reactive Oxygen Species ; Soot ; Respiratory Aerosols and Droplets ; Lung/pathology ; Bronchoalveolar Lavage Fluid/chemistry ; Weight Gain ; Inhalation Exposure/adverse effects ; Particle Size
Chemical Substances	molybdenum disulfide (ZC8B4P503V) ; Molybdenum (81AH48963U) ; Reactive Oxygen Species ; Soot
Language	English
Publishing date	2023-01-11
Publishing country	Ireland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	184557-3
ISSN	1879-3185 ; 0300-483X
ISSN (online)	1879-3185
ISSN	0300-483X
DOI	10.1016/j.tox.2023.153428
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 888: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Resistant and Recurrent Late Reaction to Hyaluronic Acid-Based Gel.

Artzi, Ofir / Loizides, Christoforos / Verner, Ines / Landau, Marina

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

2016 Volume 42, Issue 1, Page(s) 31–37

Abstract: Background: Late reactions to hyaluronic acid (HA)-based fillers have a recorded rate of 0.02%. The recent experience with a newly introduced filler in the tear trough area and the lips showed higher rate of reactions with a tendency to persistency and ... ...

Abstract	Background: Late reactions to hyaluronic acid (HA)-based fillers have a recorded rate of 0.02%. The recent experience with a newly introduced filler in the tear trough area and the lips showed higher rate of reactions with a tendency to persistency and recurrences. Objective: To delineate the features of reactions to this newly introduced filler. Materials and methods: Medical records of 400 patients (360 women and 40 men; average age = 49.6 years) were examined in this retrospective study. Juvéderm Volbella (HA-Vb) filler was injected only into the tear trough area or lips. Other HA-based products were used in other areas of the face. Results: Seventeen patients (4.25%) developed prolonged (up to 11 months) and recurrent (average: 3.17 episodes) late (average onset: 8.41 weeks after the injection) inflammatory cutaneous reactions. Conclusion: The incidence of late reactions to HA-based fillers varies between products. The authors are reporting an exceptionally high rate of cutaneous reactions for this newly introduced filler. In the authors' experience, broad-spectrum antibiotics in conjunction with repeated high-dose hyaluronidase injections into the inflammatory nodules were effective treatments.
MeSH term(s)	Adult ; Aged ; Anti-Bacterial Agents/therapeutic use ; Cosmetic Techniques/adverse effects ; Dermal Fillers/adverse effects ; Drug Eruptions/drug therapy ; Drug Eruptions/etiology ; Eye ; Female ; Gels ; Humans ; Hyaluronic Acid/administration & dosage ; Hyaluronic Acid/adverse effects ; Hyaluronoglucosaminidase/therapeutic use ; Hypopigmentation/chemically induced ; Lip ; Male ; Middle Aged ; Recurrence ; Retrospective Studies ; Skin Aging/drug effects
Chemical Substances	Anti-Bacterial Agents ; Dermal Fillers ; Gels ; Hyaluronic Acid (9004-61-9) ; Hyaluronoglucosaminidase (EC 3.2.1.35)
Language	English
Publishing date	2016-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	1227586-4
ISSN	1524-4725 ; 1076-0512
ISSN (online)	1524-4725
ISSN	1076-0512
DOI	10.1097/DSS.0000000000000562
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1212: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A mixed effects model framework for the assessment of nonlinear interactions in event-related potentials (ERPs) elicited by identical successive stimuli.

Loizides, Charalambos / Achilleos, Achilleas / Iannetti, Gian Domenico / Mitsis, Georgios D

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

2015 Volume 2014, Page(s) 4543–4546

Abstract: The recording of brain event-related potentials (ERPs) is a widely used technique to investigate the neural basis of sensory perception and cognitive processing in humans. A commonly used assumption, when dealing with potentially overlapping ERPs ... ...

Abstract	The recording of brain event-related potentials (ERPs) is a widely used technique to investigate the neural basis of sensory perception and cognitive processing in humans. A commonly used assumption, when dealing with potentially overlapping ERPs elicited by successive stimuli with interstimulus interval (ISI) smaller than the latency of the ERPs, is that their interaction is linear. These overlaps are usually dealt by using averaged waveforms, mostly to enhance the signal-to-noise ratio (SNR) and performing algebraic waveform subtractions. In this paper, we examine the hypothesis of linear interactions by providing a statistical framework that examines the presence of nonlinear additive effects between overlapping ERPs elicited by successive stimuli with short ISIs. The statistical analysis is designed for single trial rather than averaged waveforms. The results suggest that there are no nonlinear additive effects due to the time overlap per se but that, for the range of ISIs examined, the second ERP is modulated by the presence of the first stimulus irrespective of whether there is time overlap or not. In other words, two ERPs that overlap in time can still be written as an addition of two ERPs, with the second ERP being different to the first. The modulation effect on the second ERP by the first stimulus varies for different ISIs.
MeSH term(s)	Brain/physiology ; Electroencephalography/methods ; Evoked Potentials ; Humans ; Signal Processing, Computer-Assisted ; Signal-To-Noise Ratio
Language	English
Publishing date	2015-01-06
Publishing country	United States
Document type	Journal Article
ISSN	2694-0604
ISSN (online)	2694-0604
DOI	10.1109/EMBC.2014.6944634
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Assessment of nonlinear interactions in event-related potentials elicited by stimuli presented at short interstimulus intervals using single-trial data.

Loizides, Charalambos / Achilleos, Achilleas / Iannetti, Gian Domenico / Mitsis, Georgios D

Journal of neurophysiology

2015 Volume 113, Issue 10, Page(s) 3623–3633

Abstract: The recording of brain event-related potentials (ERPs) is a widely used technique to investigate the neural basis of sensory perception and cognitive processing in humans. Due to the low magnitude of ERPs, averaging of several consecutive stimuli is ... ...

Abstract	The recording of brain event-related potentials (ERPs) is a widely used technique to investigate the neural basis of sensory perception and cognitive processing in humans. Due to the low magnitude of ERPs, averaging of several consecutive stimuli is typically employed to enhance the signal to noise ratio (SNR) before subsequent analysis. However, when the temporal interval between two consecutive stimuli is smaller than the latency of the main ERP peaks, i.e., when the stimuli are presented at a fast rate, overlaps between the corresponding ERPs may occur. These overlaps are usually dealt with by assuming that there is a simple additive superposition between the elicited ERPs and consequently performing algebraic waveform subtractions. Here, we test this assumption rigorously by providing a statistical framework that examines the presence of nonlinear additive effects between overlapping ERPs elicited by successive stimuli with short interstimulus intervals (ISIs). The results suggest that there are no nonlinear additive effects due to the time overlap per se but that, for the range of ISIs examined, the second ERP is modulated by the presence of the first stimulus irrespective of whether there is time overlap or not. In other words, two ERPs that overlap in time can still be written as an addition of two ERPs but with the second ERP being different from the first. This difference is also present in the case of nonoverlapping ERPs with short ISIs. The modulation effect elicited on the second ERP by the first stimulus is dependent on the ISI value.
MeSH term(s)	Adult ; Analysis of Variance ; Biophysics ; Electroencephalography ; Evoked Potentials/physiology ; Female ; Fourier Analysis ; Healthy Volunteers ; Humans ; Male ; Middle Aged ; Nonlinear Dynamics ; Time Factors ; Young Adult
Language	English
Publishing date	2015-06-01
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80161-6
ISSN	1522-1598 ; 0022-3077
ISSN (online)	1522-1598
ISSN	0022-3077
DOI	10.1152/jn.00523.2014
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Full text

In stock of ZB MED Cologne/Königswinter

Uc I Zs.224: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito