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  1. Article ; Online: Comparing Rod-Mediated Dark Adaptation in Older Adults before and after Cataract Surgery.

    Tanaya, Tarushi / Swain, Thomas A / Clark, Mark E / Swanner, Jason C / Lolley, Virginia R / Callahan, Michael A / McGwin, Gerald / Owsley, Cynthia

    Current eye research

    2023  Volume 48, Issue 5, Page(s) 512–517

    Abstract: Purpose: Studies on age-related macular degeneration often use rod-mediated dark adaptation (RMDA) to evaluate macular functional health, studying eyes with cataract and pseudophakic eyes within the same sample. We examine a poorly understood issue- ... ...

    Abstract Purpose: Studies on age-related macular degeneration often use rod-mediated dark adaptation (RMDA) to evaluate macular functional health, studying eyes with cataract and pseudophakic eyes within the same sample. We examine a poorly understood issue-whether rod intercept time (RIT), a measure of RMDA, changes after cataract surgery and intraocular lens (IOL) insertion as compared to RIT before cataract surgery. Cataract may serve as a filter reducing photo-bleach magnitude prior to surgery, biasing RMDA interpretation.
    Methods: A pre-/post-cataract surgery design was used. Persons with nuclear sclerotic and/or cortical cataract per the electronic health record were enrolled. Prior to cataract surgery, visual acuity, RMDA, and the LOCS III classification documenting cataract presence/severity were measured. Thirty days after surgery (mean), visual acuity and RMDA were repeated, followed by fundus photos to document macular health.
    Results: Twenty-four participants (mean age 72.7 years, standard deviation 5.6) enrolled. All eyes had nuclear sclerotic and nuclear color cataract; 68% had cortical cataract. All IOLs were monofocal with 21 having blue blocking characteristics and 3 had clear IOLs. Most eyes had higher RIT post-surgery (15.6 min, SD 6.7) as compared to pre-surgery (13.7 min, SD 6.4),
    Conclusion: RMDA was significantly slower (RIT was greater) following cataract surgery, with the greatest impact on RIT in older eyes after surgery for more advanced cataract. These findings suggest that persons with more advanced cataract may bias results when evaluating RMDA using RIT.
    MeSH term(s) Humans ; Aged ; Dark Adaptation ; Cataract Extraction ; Capsule Opacification ; Visual Acuity ; Cataract/complications
    Language English
    Publishing date 2023-01-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 82079-9
    ISSN 1460-2202 ; 0271-3683
    ISSN (online) 1460-2202
    ISSN 0271-3683
    DOI 10.1080/02713683.2023.2171438
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Eye care use among a high-risk diabetic population seen in a public hospital's clinics.

    Maclennan, Paul A / McGwin, Gerald / Heckemeyer, Christine / Lolley, Virginia R / Hullett, Sandral / Saaddine, Jinan / Shrestha, Sundar S / Owsley, Cynthia

    JAMA ophthalmology

    2013  Volume 132, Issue 2, Page(s) 162–167

    Abstract: Importance: Little is known regarding eye care use among low-income persons with diabetes mellitus, especially African Americans.: Objective: To investigate eye care use among patients with diabetes who were seen in a county hospital clinic that ... ...

    Abstract Importance: Little is known regarding eye care use among low-income persons with diabetes mellitus, especially African Americans.
    Objective: To investigate eye care use among patients with diabetes who were seen in a county hospital clinic that primarily serves high-risk, low-income, non-Hispanic African American patients.
    Design, setting, and participants: A retrospective cohort study with 2 years of follow-up examined eye care use among adult patients with diabetes seen in 2007 in an outpatient medical clinic of a large, urban county hospital that primarily serves low-income, non-Hispanic African American patients. Patients with a history of retinopathy and macular edema or a current diagnosis indicating ophthalmic complications were excluded. Eye care use was defined dichotomously as whether or not patients had a visit to the eye clinic for any eye care examination or procedure. We estimated crude and adjusted rate ratios (aRRs) and 95% CIs for the association between eye care use and selected clinical and demographic characteristics.
    Results: There were 867 patients with diabetes identified: 61.9% were women, 76.2% were non-Hispanic African American, and 61.4% were indigent, with a mean age of 51.8 years. Eye care utilization rates were 33.2% within 1 and 45.0% within 2 years. For patients aged 19 to 39 years compared with those aged 65 years or older, significantly decreased eye care utilization rates were observed within 1 year (aRR, 0.48; 95% CI, 0.27-0.84) and within 2 years (aRR, 0.61; 95% CI, 0.38-0.99).
    Conclusions and relevance: Overall eye care utilization rates were low. Additional education efforts to increase the perception of need among urban minority populations may be enhanced if focused on younger persons with diabetes.
    MeSH term(s) Adult ; African Americans/ethnology ; Aged ; Aged, 80 and over ; Alabama/epidemiology ; Blindness/ethnology ; Blindness/prevention & control ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/ethnology ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/ethnology ; Diabetic Retinopathy/diagnosis ; Diabetic Retinopathy/ethnology ; Diabetic Retinopathy/therapy ; European Continental Ancestry Group/ethnology ; Female ; Follow-Up Studies ; Health Services/statistics & numerical data ; Health Services Research ; Hospitals, Public/statistics & numerical data ; Humans ; Male ; Middle Aged ; Ophthalmology ; Outpatient Clinics, Hospital/statistics & numerical data ; Retrospective Studies ; Risk Factors ; Vision, Low/ethnology ; Vision, Low/prevention & control ; Young Adult
    Language English
    Publishing date 2013-12-05
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2701705-9
    ISSN 2168-6173 ; 2168-6165
    ISSN (online) 2168-6173
    ISSN 2168-6165
    DOI 10.1001/jamaophthalmol.2013.6046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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