LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 23

Search options

  1. Article ; Online: Optimized results of the liver partition program for split-liver transplantation.

    Barrios, Oriana / Dopazo, Cristina / López-Boado, Miguel Angel / Gómez-Gavara, Concepción / Fundora Suarez, Yiliam / Torrents, Abiguei / Llado, Laura

    Cirugia espanola

    2023  Volume 102, Issue 2, Page(s) 84–89

    Abstract: Introduction: Split liver transplantation is a procedure performed throughout Europe. In 2018 in Catalonia, the distribution of donors was redefined, being potential candidates for SPLIT all those under 35-years and it was made flexible the adult ... ...

    Abstract Introduction: Split liver transplantation is a procedure performed throughout Europe. In 2018 in Catalonia, the distribution of donors was redefined, being potential candidates for SPLIT all those under 35-years and it was made flexible the adult selection for the right graft. The study aim is to evaluate the effect of this modifications on the use of Split donors on the adult/pediatric waiting lists, as well as to evaluate the post-transplant results of adults who received a Split donor.
    Methods: Observational and retrospective study; 2 data collection periods "PRE" (2013-2017) and "POST" (2018-2021). The adults recipients results were analyzed by a propensity score matching.
    Results: In the first period 3 donors were registered and 3 pediatric patients and 2 adults recieved a transplant. In the POST period, 24 donations with liver bipartition were made, performing the transplant in 19 adults and 24 childrens. When comparing the adults waiting lists, a significant decrease was evidenced, both for adults (p = 0,0001) and on the children's waiting list (p = 0,0004), and up to 3 times there were no recipients on the pediatric waiting list. No significant differences between hospital morbidity or mortality or overall survival were observed in the group of adult recipients of Split grafts.
    Conclusions: The flexibility in the selection of the adult recipient and the new distribution of donors makes possible to increase the bipartition rate, reducing the pediatric waiting list without worsening the adults results transplant recipients or their permanence on the waiting list.
    MeSH term(s) Adult ; Child ; Humans ; Liver Transplantation/methods ; Retrospective Studies ; Liver ; Tissue Donors ; Europe
    Language English
    Publishing date 2023-11-21
    Publishing country Spain
    Document type Observational Study ; Journal Article
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.cireng.2023.07.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Unilateral axilo-breast approach (UABA) with gas insufflation versus open conventional hemithyroidectomy: A prospective comparative study.

    Saavedra-Pérez, David / Manyalich, Marti / Domínguez, Paula / Farguell, Jordi / Rull, Ramón / López-Boado, Miguel Ángel / Vilaça, Jaime / Vidal, Óscar

    Cirugia espanola

    2022  Volume 101, Issue 2, Page(s) 107–115

    Abstract: Background: The objective of this study was to compare with the conventional open approach, the surgical and aesthetic results of endoscopic thyroidectomy via unilateral axillo-breast approach (UABA) with gas insufflation in patients with a unilateral ... ...

    Abstract Background: The objective of this study was to compare with the conventional open approach, the surgical and aesthetic results of endoscopic thyroidectomy via unilateral axillo-breast approach (UABA) with gas insufflation in patients with a unilateral thyroid nodule.
    Methods: Between August 2017 and August 2020, a prospective comparative cohort study was carried out in patients proposed for hemithyroidectomy. The patients were assigned to one type of approach (Open or Endoscopic) in a successive manner. Surgical results and aesthetic satisfaction at hospital discharge and during the 12-month follow-up were evaluated and compared between both groups.
    Results: A total of 200 patients were included in the study: 100 for the Open approach and 100 for the Endoscopic. The baseline patient characteristics were similar between both groups. Total operative time was longer in the Endoscopic approach, due to the time required for subcutaneous dissection (the hemithyroidectomy time was similar in both groups). There was no significant difference in the frequency of major complications. The length of hospital stay was longer (for 1 day) in the Endoscopic group. The aesthetic satisfaction of the patients was significantly higher in the Endoscopic than in the Open group (p < 0.001), at hospital discharge and at 12-month follow-up.
    Conclusion: UABA with gas insufflation for hemithyroidectomy represents a safe and effective therapeutic option for the treatment of unilateral benign thyroid pathologies.
    MeSH term(s) Humans ; Thyroidectomy/methods ; Thyroid Neoplasms/surgery ; Thyroid Neoplasms/pathology ; Insufflation ; Prospective Studies ; Cohort Studies
    Language English
    Publishing date 2022-09-12
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.cireng.2022.09.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Minimally-invasive endocrine neck surgery.

    Vidal, Oscar / Saavedra-Perez, David / Vilaça, Jaime / Pantoja, Juan Pablo / Delgado-Oliver, Eduardo / Lopez-Boado, Miguel Angel / Fondevila, Constantino

    Cirugia espanola

    2019  Volume 97, Issue 6, Page(s) 305–313

    Abstract: Minimally invasive approaches for endocrine surgery of the neck are the result of efforts by several surgeons to extrapolate to neck surgery the proven benefits of minimally invasive techniques from other regions of the body, including less pain, ... ...

    Title translation Cirugía endocrina cervical mínimamente invasiva.
    Abstract Minimally invasive approaches for endocrine surgery of the neck are the result of efforts by several surgeons to extrapolate to neck surgery the proven benefits of minimally invasive techniques from other regions of the body, including less pain, morbidity and hospital stay. However, the main argument that led to the introduction of these techniques was the improvement of esthetic results. Endoscopic and robotic remote-access endocrine neck approaches through small incisions have been developed over the last 25 years and are constantly being refined. The objective of this review is to determine the current state of the literature through a systematic evaluation of the different techniques available in minimally invasive endocrine surgery of the neck, either with or without remote access, by describing their main characteristics and evaluating their advantages, disadvantages and controversies, while discussing their role and future in neck surgery.
    MeSH term(s) Humans ; Minimally Invasive Surgical Procedures/adverse effects ; Minimally Invasive Surgical Procedures/methods ; Neck/surgery ; Robotic Surgical Procedures/adverse effects ; Robotic Surgical Procedures/methods ; Surgery, Plastic/methods ; Thyroid Diseases/surgery ; Thyroidectomy/adverse effects ; Thyroidectomy/methods ; Treatment Outcome
    Language Spanish
    Publishing date 2019-05-28
    Publishing country Spain
    Document type Journal Article ; Review
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.ciresp.2019.03.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Validation of the Back-table Graft Arterial Anastomosis between the Splenic Artery and Superior Mesenteric Artery: Arterial Complications after a 21-year Single-center Experience of Pancreas Transplantation.

    Ferrer-Fàbrega, Joana / Cárdenas, Gabriel / Sapena, Víctor / García-Criado, Ángeles / Barrufet, Marta / Pérez, Carles / García-Pérez, Rocío / Rull, Ramón / López-Boado, Miguel Ángel / Folch-Puy, Emma / Torroella, Alba / Ventura-Aguiar, Pedro / Cofan, Federico / Esmatjes, Enric / Amor, Antonio / Diekmann, Fritz / Fernández-Cruz, Laureano / García-Valdecasas, Juan Carlos / Fuster, Josep

    Annals of surgery

    2023  

    Abstract: Objective: To determine the role of the arterial splenomesenteric anastomosis (ASMA) vascular reconstruction technique in terms of arterial vascular complications in pancreas transplant (PT) recipients.: Summary background data: The ASMA technique ... ...

    Abstract Objective: To determine the role of the arterial splenomesenteric anastomosis (ASMA) vascular reconstruction technique in terms of arterial vascular complications in pancreas transplant (PT) recipients.
    Summary background data: The ASMA technique was first described in 1992 by Hospital Clínic Barcelona group. Regardless that the iliac Y-graft technique is the most frequently used worldwide, evidence of arterial complications and implications of using a different back-table reconstruction is conspicuously absent in the literature.
    Methods: Descriptive review of 407 PTs performed at a single center (1999-2019) by analyzing the type of arterial reconstruction technique, focusing on ASMA. The endpoints were the management of arterial complications and long-term patient and graft survival.
    Results: ASMA was performed in 376 cases (92.4%) and a Y-graft in 31 cases (7.6%). A total of 34 arterial complications (8.3%) were diagnosed. In the ASMA group (n=30, 7.9%) they comprised: 15 acute thrombosis; 4 stenosis; 1 pseudoaneurysm and 10 diverse chronic arterial complications while in the Y-graft group (n=4, 12.9%) 3 acute thrombosis and 1 chronic artery-duodenal fistula occurred. Graft salvage was achieved in 16 patients (53.3%) from the ASMA group and in 2 (50%) from the Y-graft. After a median follow-up of 129.2 (IQR 25-75%, 77.2 -182) months the overall graft and patient survival for the whole cohort at 1, 5, and 10 years was 86.7%, 79.5%, 70.5%, and 98.5%, 95.3%, 92.5%, respectively.
    Conclusions: The ASMA proves to be a safe and more easily reproducible technique and should therefore be considered for first-line back-table reconstruction in the PT population.
    Language English
    Publishing date 2023-12-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000006188
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Current Trends in Organ Preservation Solutions for Pancreas Transplantation: A Single-Center Retrospective Study.

    Ferrer-Fàbrega, Joana / Folch-Puy, Emma / Lozano, Juan José / Ventura-Aguiar, Pedro / Cárdenas, Gabriel / Paredes, David / García-Criado, Ángeles / Bombí, Josep Antoni / García-Pérez, Rocío / López-Boado, Miguel Ángel / Rull, Ramón / Esmatjes, Enric / Ricart, Maria José / Diekmann, Fritz / Fondevila, Constantino / Fernández-Cruz, Laureano / Fuster, Josep / García-Valdecasas, Juan Carlos

    Transplant international : official journal of the European Society for Organ Transplantation

    2022  Volume 35, Page(s) 10419

    Abstract: Due to the high vulnerability of the pancreas to ischemia-reperfusion injury, choices regarding preservation solution markedly affect pancreas transplant success. A retrospective single-center analysis of 380 pancreas transplants (2000-2019) was ... ...

    Abstract Due to the high vulnerability of the pancreas to ischemia-reperfusion injury, choices regarding preservation solution markedly affect pancreas transplant success. A retrospective single-center analysis of 380 pancreas transplants (2000-2019) was performed to correlate current preservation solutions with transplant outcomes. Early graft failure requiring transplantectomy within 30 days post-transplant occurred in 7.5% for University of Wisconsin (UW) group (
    MeSH term(s) Glucose ; Humans ; Insulin/therapeutic use ; Organ Preservation ; Organ Preservation Solutions ; Pancreas ; Pancreas Transplantation ; Retrospective Studies
    Chemical Substances Insulin ; Organ Preservation Solutions ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2022-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.3389/ti.2022.10419
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Repeated pancreatectomy after pancreato-duodenectomy for a intraductal papillary mucinous tumour: advantage of pancreatico-gastrostomy with a gastric partition.

    Fernández-Cruz, Laureano / López-Boado, Miguel-Angel / Ferrer, Joana

    HPB : the official journal of the International Hepato Pancreato Biliary Association

    2011  Volume 14, Issue 2, Page(s) 132–135

    Abstract: Background:   Regular follow-up and monitoring of intraductal papillary mucinous neoplasms (IPMN) is important as there is a risk of recurrence in both the non-invasive and invasive IPMN.: Methods:   Three patients developed pancreatic remnant ... ...

    Abstract Background:   Regular follow-up and monitoring of intraductal papillary mucinous neoplasms (IPMN) is important as there is a risk of recurrence in both the non-invasive and invasive IPMN.
    Methods:   Three patients developed pancreatic remnant recurrence after a pancreatico-duodenectomy for IPMN. Pancreatico-gastrostomy anastomosis was performed in all patients. Long-term follow-up was performed with radiographical surveillance and by endoscopic gastroscopy.
    Results:   Magnetic resonance imaging (MRI) and endoscopic ultrasonography (EUS) revealed in one patient, 2 years after surgery, a 3-cm mass at the site of the anastomosis and dilatation of the Wirsung duct >6 mm in two other patients (2 and 3 years after surgery, respectively). The diagnosis of recurrence was confirmed endoscopically by the presence of a large amount of mucin at the anastomotic site. Cytological examination revealed moderate dysplasia. Opacification of the Wirsung duct after endoscopic retrograde cholangiopancreatography (ERCP) was only possible in one patient in whom an irregular stenosis of the duct was observed.
    Conclusions:   Long-term follow-up of the pancreatic remnant after pancreato-duodenectomy for IPMN is better achieved with pancreatico-gastrostomy anastomosis.
    MeSH term(s) Adenocarcinoma, Mucinous/pathology ; Adenocarcinoma, Mucinous/surgery ; Aged ; Carcinoma, Pancreatic Ductal/pathology ; Carcinoma, Pancreatic Ductal/surgery ; Carcinoma, Papillary/pathology ; Carcinoma, Papillary/surgery ; Cholangiopancreatography, Endoscopic Retrograde ; Endosonography ; Female ; Gastroscopy ; Gastrostomy ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/surgery ; Neoplasm, Residual ; Pancreatectomy ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/surgery ; Pancreaticoduodenectomy/adverse effects ; Reoperation ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2011-11-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2131251-5
    ISSN 1477-2574 ; 1365-182X
    ISSN (online) 1477-2574
    ISSN 1365-182X
    DOI 10.1111/j.1477-2574.2011.00415.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Early intestinal complications following pancreas transplantation: lessons learned from over 300 cases - a retrospective single-center study.

    Ferrer-Fàbrega, Joana / Cano-Vargas, Brenda / Ventura-Aguiar, Pedro / Cárdenas, Gabriel / García-Criado, Ángeles / López-Boado, Miguel Angel / Rull, Ramón / García, Rocío / Cuatrecasas, Miriam / Esmatjes, Enric / Diekmann, Fritz / Fondevila, Constantino / Ricart, Mª José / Fernández-Cruz, Laureano / Fuster, Josep / García-Valdecasas, Juan Carlos

    Transplant international : official journal of the European Society for Organ Transplantation

    2020  Volume 34, Issue 1, Page(s) 139–152

    Abstract: Enteric complications remain a major cause of morbidity in the post-transplant period of pancreas transplantation despite improvements surgical technique. The aim of this single-center study was to analyze retrospectively the early intestinal ... ...

    Abstract Enteric complications remain a major cause of morbidity in the post-transplant period of pancreas transplantation despite improvements surgical technique. The aim of this single-center study was to analyze retrospectively the early intestinal complications and their potential relation with vascular events. From 2000 to 2016, 337 pancreas transplants were performed with systemic venous drainage. For exocrine secretion, intestinal drainage was done with hand-sewn anastomosis duodenojejunostomy. Twenty-three patients (6.8%) had early intestinal complications. Median age was 39 years (male: 65.2%). Median cold ischemia time was 11 h [IQR: 9-12.4]. Intestinal complications were intestinal obstruction (n = 7); paralytic ileus (n = 5); intestinal fistula without anastomotic dehiscence (n = 3); ischemic graft duodenum (n = 3); dehiscence of duodenojejunostomy (n = 4); and anastomotic dehiscence in jejunum after pancreas transplantectomy (n = 1). Eighteen cases required relaparotomy: adhesiolysis (n = 6); repeated laparotomy without findings (n = 1); transplantectomy (n = 6); primary leak closure (n = 3); re-positioning of the graft (n = 1); and intestinal resection (n = 1). Of the intestinal complications, 4 were associated with vascular thrombosis, resulting in two pancreatic graft losses. Enteric drainage with duodenum-jejunum anastomosis is safe and feasible, with a low rate of intra-abdominal complications. Vascular thrombosis associated with intestinal complications presents a risk factor for the viability of pancreatic grafts, so prevention and early detection is vital.
    MeSH term(s) Adult ; Anastomosis, Surgical/adverse effects ; Drainage ; Humans ; Male ; Pancreas Transplantation/adverse effects ; Postoperative Complications/etiology ; Retrospective Studies
    Language English
    Publishing date 2020-11-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.1111/tri.13775
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Epidemiology, risk factors, and impact of bacterial infections on outcomes for pancreatic grafts.

    Bodro, Marta / Ferrer, Joana / Ricart, María José / Sanclemente, Gemma / Linares, Laura / Cervera, Carlos / Cofan, Frederic / Ventura-Aguiar, Pedro / Lopez-Boado, Miguel Ángel / Marco, Francesc / Fuster, Josep / García-Valdecasas, Juan Carlos / Moreno, Asunción

    Clinical transplantation

    2018  Volume 32, Issue 8, Page(s) e13333

    Abstract: We aimed to determine the epidemiology, risk factors, and impact of bacterial infection on pancreatic function after pancreas transplantation. Data for pancreas transplant recipients were retrospectively reviewed between 2000 and 2014 for at least 1 year. ...

    Abstract We aimed to determine the epidemiology, risk factors, and impact of bacterial infection on pancreatic function after pancreas transplantation. Data for pancreas transplant recipients were retrospectively reviewed between 2000 and 2014 for at least 1 year. We collected and analyzed post-transplant data for bacterial infection, morbidity, and mortality. During the study period, 312 pancreas transplants were performed. In total, 509 episodes of bacterial infection were diagnosed in 191 patients (61%). Multidrug-resistant (MDR) organisms were present in 173 of the 513 isolated microorganisms (33%). Risk factors independently associated with bacterial infection were acute allograft rejection (OR 1.7, 95%CI 1.1-3), the need for post-transplant hemodialysis, (OR 5.3, 95%CI 1.8-15.7) and surgical re-intervention (OR 2.8, 95%CI 1.5-5.1), which was also considered a risk factor for infections caused by MDR bacteria. Graft survival was associated with the occurrence of one or more episodes of bacterial infection (log-rank test = 0.009). Surgical re-intervention was independently associated with graft loss (OR 2.5, 95%CI 1.3-4.7). To conclude, pancreas recipients frequently experienced bacterial infections associated with the need for hemodialysis or surgical re-intervention. Infection by MDR organisms is a growing concern in these patients and was related to graft survival. Graft loss was independently associated with surgical re-intervention.
    MeSH term(s) Adolescent ; Adult ; Bacterial Infections/complications ; Bacterial Infections/epidemiology ; Bacterial Infections/microbiology ; Drug Resistance, Multiple, Bacterial ; Female ; Follow-Up Studies ; Graft Rejection/complications ; Graft Rejection/epidemiology ; Graft Rejection/microbiology ; Graft Survival ; Humans ; Incidence ; Male ; Middle Aged ; Pancreas Transplantation/adverse effects ; Postoperative Complications/epidemiology ; Postoperative Complications/microbiology ; Prognosis ; Prospective Studies ; Retrospective Studies ; Risk Factors ; Spain/epidemiology ; Young Adult
    Language English
    Publishing date 2018-08-20
    Publishing country Denmark
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 639001-8
    ISSN 1399-0012 ; 0902-0063
    ISSN (online) 1399-0012
    ISSN 0902-0063
    DOI 10.1111/ctr.13333
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Outcomes of pancreatogastrostomy with gastric partition after pylorus-preserving pancreaticoduodenectomy with gastric partition.

    Sánchez Cabús, Santiago / Saavedra, David / Sampson, Jaime / Cubel, Marc / López-Boado, Miguel Ángel / Ferrer, Joana / Fernández-Cruz, Laureano

    Cirugia espanola

    2015  Volume 93, Issue 8, Page(s) 502–508

    Abstract: Introduction: Pylorus-preserving pancreatoduodenectomy with gastric partition (PPPD-GP) seems to be associated to a better postoperative outcome than conventional pancreaticojejunostomy in the setting of a prospective-randomized study. The aim of this ... ...

    Abstract Introduction: Pylorus-preserving pancreatoduodenectomy with gastric partition (PPPD-GP) seems to be associated to a better postoperative outcome than conventional pancreaticojejunostomy in the setting of a prospective-randomized study. The aim of this study is to further evaluate the surgical outcome in a series of 129 consecutive patients.
    Methods: Between 2007 and June 2013, 129 patients with periampullary tumors surgically treated with PPPD-GP were retrospectively analyzed. Surgical complications (Clavien-Dindo score), as well as pancreatic and non-pancreas related complications were analyzed.
    Results: Overall postoperative complication rate was 77%, although 50% of complications were graded I-II by the Clavien-Dindo classification. Incidence of clinically relevant pancreatic fistula was 18%: ISGFP type B: 12%, and type C: 6%. Other pancreas specific complications such as delayed gastric emptying and pospancreatectomy haemorrhage were 27 and 15%, respectively, similar to results published in the literature. Overall perioperative mortality rate was 4.6%.
    Conclusion: PPPD-GP results show that it is a technique with an acceptable morbidity, low mortality and pancreatic fistula rate similar to other techniques currently described of pancreaticoenteric reconstruction.
    MeSH term(s) Female ; Humans ; Male ; Middle Aged ; Organ Sparing Treatments ; Pancreatic Neoplasms/surgery ; Pancreaticoduodenectomy/methods ; Pancreaticojejunostomy/methods ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Pylorus ; Retrospective Studies ; Stomach/surgery ; Treatment Outcome
    Language Spanish
    Publishing date 2015-10
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 730701-9
    ISSN 1578-147X ; 0009-739X
    ISSN (online) 1578-147X
    ISSN 0009-739X
    DOI 10.1016/j.ciresp.2015.04.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Pancreas transplantation: Advantages of a retroperitoneal graft position.

    Ferrer, Joana / Molina, Víctor / Rull, Ramón / López-Boado, Miguel Ángel / Sánchez, Santiago / García, Rocío / Ricart, Ma José / Ventura-Aguiar, Pedro / García-Criado, Ángeles / Esmatjes, Enric / Fuster, Josep / Garcia-Valdecasas, Juan Carlos

    Cirugia espanola

    2017  Volume 95, Issue 9, Page(s) 513–520

    Abstract: Introduction: In the 50 years since the first pancreas transplant performed at the University of Minnesota, the surgical techniques employed have undergone many modifications. Techniques such as retroperitoneal graft placement have further improved the ... ...

    Title translation Trasplante de páncreas: ventajas de la posición retroperitoneal del injerto.
    Abstract Introduction: In the 50 years since the first pancreas transplant performed at the University of Minnesota, the surgical techniques employed have undergone many modifications. Techniques such as retroperitoneal graft placement have further improved the ability to reproduce the physiology of the «native» pancreas. We herein present our experience of a modified technique for pancreatic transplant, with the organ placed into a fully retroperitoneal position with systemic venous and enteric drainage of the graft by duodeno-duodenostomy.
    Methods: All pancreas transplantations performed between May 2016 and January 2017 were prospectively entered into our transplant database and retrospectively analyzed.
    Results: A total of 10 transplants were performed using the retroperitoneal technique (6 men: median age of 41 years [IQR 36-54]). Median cold ischemia times was 10,30h [IQR 5,30-12,10]. The preservation solution used was Celsior (n=7), IGL-1 (n=2), and UW (n=1). No complications related to the new surgical technique were identified. In one patient, transplantectomy at 12h was performed due to graft thrombosis, probably related to ischemic conditions from a donor with prolonged cardio-respiratory arrest. Another procedure was aborted without completing the graft implant due to an intraoperative immediate arterial thrombosis in a patient with severe iliac atheromatosis. No primary pancreas non-function occurred in the remaining 8patients. The median hospital stay was 13,50 days [IQR 10-27].
    Conclusions: Retroperitoneal graft placement appears feasible with easy access for dissection the vascular site; comfortable technical vascular reconstruction; and a decreased risk of intestinal obstruction by separation of the small bowel from the pancreas graft.
    MeSH term(s) Adult ; Diabetes Mellitus, Type 1/surgery ; Female ; Humans ; Male ; Middle Aged ; Pancreas Transplantation/methods ; Retroperitoneal Space ; Retrospective Studies ; Young Adult
    Language Spanish
    Publishing date 2017-11
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 730701-9
    ISSN 1578-147X ; 0009-739X
    ISSN (online) 1578-147X
    ISSN 0009-739X
    DOI 10.1016/j.ciresp.2017.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top