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Article ; Online: Use of Tissue Microarray in Esophageal Squamous Cell Carcinoma.

Lam, Alfred K / Lor, David K

Methods in molecular biology (Clifton, N.J.)

2020  Volume 2129, Page(s) 119–135

Abstract: Tissue microarray (TMA) is widely used for identifying the expression of markers in many tissues from patients with esophageal squamous cell carcinoma. The technology is mostly used in immunohistochemical studies to test the expression of markers and ... ...

Abstract Tissue microarray (TMA) is widely used for identifying the expression of markers in many tissues from patients with esophageal squamous cell carcinoma. The technology is mostly used in immunohistochemical studies to test the expression of markers and oncoproteins in signalling pathway as well as targeting proteins involved in therapies for esophageal squamous cell carcinoma. Appropriate use of TMA sections needs consideration of labor, planning, and expertise involved. For the best performance, it is important to design the layout of the TMA as well as use whole-slide scanning for interpretation of the TMA sections.
MeSH term(s) Biomarkers, Tumor/metabolism ; Carcinoma, Squamous Cell/pathology ; Esophageal Neoplasms/pathology ; Esophageal Squamous Cell Carcinoma/classification ; Esophageal Squamous Cell Carcinoma/pathology ; Esophagus/pathology ; Female ; Humans ; Male ; Mouth Neoplasms/pathology ; Specimen Handling/methods ; Tissue Array Analysis/methods
Chemical Substances Biomarkers, Tumor
Language English
Publishing date 2020-02-13
Publishing country United States
Document type Journal Article
ISSN 1940-6029
ISSN (online) 1940-6029
DOI 10.1007/978-1-0716-0377-2_10
Database MEDical Literature Analysis and Retrieval System OnLINE

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