Article ; Online: Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach
Nature Communications, Vol 10, Iss 1, Pp 1-
2019 Volume 16
Abstract: How a precancerous form (dysplasia) becomes gastric cancer is unclear. Here, the authors assess the role of Kras activation in heterogenous dysplastic cells in murine stomach corpus organoids, identifying two dysplastic stem cell populations and show ... ...
Abstract | How a precancerous form (dysplasia) becomes gastric cancer is unclear. Here, the authors assess the role of Kras activation in heterogenous dysplastic cells in murine stomach corpus organoids, identifying two dysplastic stem cell populations and show that MEK inhibition causes alterations in cell behavior. |
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Keywords | Science ; Q |
Language | English |
Publishing date | 2019-12-01T00:00:00Z |
Publisher | Nature Publishing Group |
Document type | Article ; Online |
Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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