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  1. Article ; Online: Paving the way: Exploring the efficacy of anti-choking suction devices in foreign body airway obstruction.

    Lorente-Ros, Alvaro / Rubio Soler, Pilar / Curto Prieto, David / Fernández Lozano, Ignacio

    Resuscitation plus

    2023  Volume 15, Page(s) 100441

    Language English
    Publishing date 2023-08-04
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2666-5204
    ISSN (online) 2666-5204
    DOI 10.1016/j.resplu.2023.100441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Response to Readers' Comments "Effect of Anticoagulation Duration on Stroke Incidence in Asian Patients With Left Ventricular Thrombus".

    Lorente-Ros, Álvaro / Alonso-Salinas, Gonzalo L / Monteagudo Ruiz, Juan M / Zamorano Gómez, José L

    The American journal of cardiology

    2023  Volume 191, Page(s) 143–144

    MeSH term(s) Humans ; Incidence ; Thrombosis/drug therapy ; Thrombosis/epidemiology ; Thrombosis/prevention & control ; Stroke/epidemiology ; Stroke/etiology ; Stroke/prevention & control ; Blood Coagulation ; Anticoagulants/therapeutic use
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2023-01-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2022.12.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Dataset for the study of the effect of anticoagulation in the incidence of stroke and other outcomes in patients with left ventricular thrombus.

    Lorente-Ros, Álvaro / Lorente-Ros, Marta / Alonso-Salinas, Gonzalo L / Monteagudo Ruiz, Juan M / Fernández Golfín, Covadonga / Zamorano Gómez, José L

    Data in brief

    2023  Volume 50, Page(s) 109469

    Abstract: The optimal duration of anticoagulation in patients with left ventricular thrombus (LVT) is unknown. The data package herein presented contains the information used to assess the effect of duration of anticoagulation in the incidence of stroke in ... ...

    Abstract The optimal duration of anticoagulation in patients with left ventricular thrombus (LVT) is unknown. The data package herein presented contains the information used to assess the effect of duration of anticoagulation in the incidence of stroke in patients with left ventricular thrombus (LVT) in a tertiary hospital. In order to collect the required data, all transthoracic echocardiography studies at our institution from January 1st 2014 to December 31st 2021 with LVT were retrieved using dedicated software (Phillips Intellispace Cardiovascular; Koninklijke Phillips N.V., 2004-2020). Second, a dataset was designed ad hoc for this study in which the recruited data for the predefined objectives were obtained from electronic medical records. These data included clinical and demographic information including treatment choices (vitamin K antagonists [VKA] versus direct oral anticoagulants [DOAC]), duration of treatment, reason for interruption of treatment, occurrence of stroke, acute myocardial infarction, bleeding events, thrombus resolution, recurrence, and death. Retrieved data were stored in an excel sheet for analysis using the statistical package STATA (StataCorp v. 15.0, College station, TX). This methodology allows the reuse of these data for further analysis, in the context of the present study and also for future recruitment of additional patients from other institutions to increase statistical power.
    Language English
    Publishing date 2023-08-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2786545-9
    ISSN 2352-3409 ; 2352-3409
    ISSN (online) 2352-3409
    ISSN 2352-3409
    DOI 10.1016/j.dib.2023.109469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Response to ECG, May 2020.

    Rajjoub Al-Mahdi, Ez Alddin / Lorente Ros, Álvaro / Lozano Granero, Vanesa Cristina

    Revista espanola de cardiologia (English ed.)

    2020  Volume 73, Issue 6, Page(s) 502

    Language Spanish
    Publishing date 2020-06-05
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2019.11.010
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  5. Article ; Online: ECG, May 2020.

    Rajjoub Al-Mahdi, Ez Alddin / Lorente Ros, Álvaro / Lozano Granero, Vanesa Cristina

    Revista espanola de cardiologia (English ed.)

    2020  Volume 73, Issue 5, Page(s) 408

    Language Spanish
    Publishing date 2020-05-04
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2019.11.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Efficacy and safety of Proglide use and early discharge after atrial fibrillation ablation compared to standard approach. PROFA trial.

    Castro-Urda, Víctor / Segura-Dominguez, Melodi / Jiménez-Sánchez, Diego / Aguilera-Agudo, Cristina / García-Izquierdo, Eusebio / De la Rosa Rojas, Yuleisi / Pham-Trung, Chinh / Hernández-Terciado, Fernando / Lorente-Ros, Alvaro / Matutano-Muñoz, Andrea / García-Rodriguez, Daniel / Toquero-Ramos, Jorge / Fernández-Lozano, Ignacio

    Pacing and clinical electrophysiology : PACE

    2023  Volume 46, Issue 7, Page(s) 598–606

    Abstract: Background and objectives: The common practice after atrial fibrillation ablation is to admit patients for an overnight stay. The aim of this study was to compare a strategy of vascular suture mediated closure system utilization and early discharge ( ... ...

    Abstract Background and objectives: The common practice after atrial fibrillation ablation is to admit patients for an overnight stay. The aim of this study was to compare a strategy of vascular suture mediated closure system utilization and early discharge (strategy A) compared to traditional closure and overnight hospitalization (strategy B) regarding feasibility, safety, quality of life and health care cost effectiveness.
    Methods and results: Hundred patients were randomized to compare both strategies. No clinical differences were reported except diabetes mellitus. Six patients (6%) had and emergency visit or were admitted in the first 30 days after procedure. Three occurred in strategy A versus three in strategy B (p = 1) (p < .005 for non-inferiority). Forty out of 50 patients (80%) were safely discharged in a time frame of 3 h and 42 patients (84%) were discharged in the same day of the procedure in strategy A. Time to discharge was shorter in strategy A compared to strategy B. (5.89 ± 7.47 h vs. 27.09 ± 2.29 p < .005). No differences were obtained in quality-of-life outcomes. Mean (95% CI) euros cost saving per patient in strategy A was 379.16 ± 93.55 p < .001. Ten acute complications (10% patients CI 95% 4.02%-15.98%) were reported during the trial. Seven (14% CI 95% 4.04%-23.96%) occurred in strategy A patients versus 3 (6% CI 95% 0.8%-12.8%) in strategy B. (p = .182) CONCLUSION: A strategy of vascular suture mediated closure system utilization and early discharge was feasible, reduced time to discharge, saved costs and was not associated with more complications or admissions/emergency visits in a 30-day time frame after procedure compared to a strategy of regular admission and discharge after overnight stay. There were no differences regarding quality-of-life parameters between both strategies.
    MeSH term(s) Humans ; Atrial Fibrillation/surgery ; Atrial Fibrillation/etiology ; Patient Discharge ; Quality of Life ; Hospitalization ; Punctures ; Treatment Outcome ; Catheter Ablation
    Language English
    Publishing date 2023-06-13
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.14753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Checkpoint Immunotherapy-Induced Myocarditis and Encephalitis Complicated With Complete AV Block: Not All Hope Is Lost.

    Lorente-Ros, Álvaro / Rajjoub-Al-Mahdi, Ez-Alddin / Monteagudo Ruiz, Juan M / Rivas García, Sonia / Ortega Pérez, Rodrigo / Fernández Golfín, Covadonga / Álvarez-García, Jesús / Zamorano Gómez, José L

    JACC. Case reports

    2022  Volume 4, Issue 16, Page(s) 1032–1036

    Abstract: Immune checkpoint inhibitors are associated with a myriad of autoimmune adverse events. We present a 70-year-old patient with renal-cell carcinoma treated with nivolumab/ipilimumab complicated with myocarditis and encephalitis in which gradual impairment ...

    Abstract Immune checkpoint inhibitors are associated with a myriad of autoimmune adverse events. We present a 70-year-old patient with renal-cell carcinoma treated with nivolumab/ipilimumab complicated with myocarditis and encephalitis in which gradual impairment of the His-Purkinje system progressed to complete atrioventricular block. Full recovery was achieved after treatment with corticosteroids and immunoglobulins. (
    Language English
    Publishing date 2022-08-17
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2022.04.020
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  8. Article: Serological short-chain fatty acid and trimethylamine N-oxide microbial metabolite imbalances in young adults with acute myocardial infarction.

    Avendaño-Ortiz, José / Lorente-Ros, Álvaro / Briones-Figueroa, Andrea / Morán-Alvarez, Patricia / García-Fernández, Antia / Garrote-Corral, Sandra / Amil-Casas, Irene / Carrasco-Sayalero, Ángela / Tejada-Velarde, Amalia / Camino-López, Asunción / Jiménez-Mena, Manuel / Del Campo, Rosa / Villalobos-Sánchez, Lourdes / García-Villanueva, María Jesús

    Heliyon

    2023  Volume 9, Issue 10, Page(s) e20854

    Abstract: Acute myocardial infarction (AMI) is associated with systemic inflammatory processes and metabolic alterations. Microbial-derived metabolites, such as short-chain fatty acids and trimethylamine N-oxide (TMAO), have emerged in recent years as key players ... ...

    Abstract Acute myocardial infarction (AMI) is associated with systemic inflammatory processes and metabolic alterations. Microbial-derived metabolites, such as short-chain fatty acids and trimethylamine N-oxide (TMAO), have emerged in recent years as key players in the modulation of inflammation, with potential implications for cardiovascular diseases. We performed a prospective observational study that monitored the serological concentration of bacterial metabolites in 45 young patients (<55 years) without cardiovascular risk factors but with AMI, at hospital admission and at 3 months of follow-up, and compared them with a control group. TMAO and acetate levels were significantly higher in AMI, whereas butyrate and propionate were significantly lower. The acetate/propionate ratio showed the most discrimination between AMI and controls by receiver operating characteristic analysis (area under the curve 0.769,
    Language English
    Publishing date 2023-10-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e20854
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  9. Article ; Online: Feasibility and safety of left bundle branch area pacing in cardiac amyloidosis. A single center experience.

    Pham-Trung, Chinh / Veloza-Urrea, Darwin / Segura-Domínguez, Melodie / De la Rosa Rojas, Yuleisy / Aguilera-Agudo, Cristina / García-Izquierdo, Eusebio Alejandro / García-Rodríguez, Daniel / Jiménez-Sánchez, Diego / Lorente-Ros, Alvaro / Mingo-Santos, Susana / Gonzalez-Lopez, Esther / Domínguez, Fernando / Garcia-Pavia, Pablo / Toquero-Ramos, Jorge / Fernández-Lozano, Ignacio / Castro-Urda, Víctor

    Pacing and clinical electrophysiology : PACE

    2023  Volume 47, Issue 1, Page(s) 149–155

    Abstract: Background: Conventional right ventricle (RV) pacemaker stimulation has been associated with worse clinical outcomes in patients with cardiac amyloidosis (CA). Left bundle branch area pacing (LABPP) has been suggested as a promising alternative. We ... ...

    Abstract Background: Conventional right ventricle (RV) pacemaker stimulation has been associated with worse clinical outcomes in patients with cardiac amyloidosis (CA). Left bundle branch area pacing (LABPP) has been suggested as a promising alternative. We sought to assess the safety, feasibility, and outcomes of LABPP in patients with CA.
    Methods: We retrospectively analyzed echocardiography and pacing parameters and clinical outcomes in 23 consecutive patients with CA and LBBAP implanted from June 2020 to October 2022.
    Results: LBBAP was successfully performed in 22 over 23 patients (19 male, 78.6 ± 11.7 years, 20 ATTR, mean LVEF 45.5 ± 16.2%). After the procedure, 9 patients showed Qr pattern and 11 a qR pattern in V1 on ECG. Average procedure time was 67 ± 28 min. After 7.7 ± 5.2 months follow-up, no procedure-related complications had occurred. Although, a significant reduction in QRS width (p = .001) was achieved, we did not observe significant changes in LVEF and Nt ProBNP at 6 months of follow-up. Pacing parameters were stable during follow-up: LBB capture threshold and R wave amplitude were 1.0 ±  0.5 V and 10.6 ± 6.0 mV versus 0.8 ±  0.1 V, p = .21 and 10.6 ± 5.1 mV (p = .985) at follow up.
    Conclusion: LBBAP is safe and feasible pacing technique for patients with CA. LBBAP is associated with significant narrowing of QRSd without worsening in LVEF and Nt-proBNP.
    MeSH term(s) Humans ; Male ; Feasibility Studies ; Retrospective Studies ; Ventricular Septum ; Amyloidosis/therapy ; Heart Ventricles ; Electrocardiography ; Cardiac Pacing, Artificial ; Bundle of His ; Treatment Outcome
    Language English
    Publishing date 2023-12-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.14894
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  10. Article ; Online: Value of advanced interatrial block in the diagnosis of the ischemic stroke's aetiology: A cohort study.

    Vieitez Florez, Jose Maria / Sánchez Sánchez, Arantxa / Martínez Moya, Rafael / Masjuan Vallejo, Jaime / Franco Díez, Eduardo / Jimenez-Blanco Bravo, Marta / Abellas Sequeiros, Maria / Lorente Ros, Alvaro / Zamorano Gómez, Jose Luis / Alonso Salinas, Gonzalo Luis

    Medicina clinica

    2022  Volume 159, Issue 6, Page(s) 278–282

    Abstract: Introduction and objectives: Advanced interatrial block has been linked with atrial fibrillation (AF) (Bayes syndrome). On the other hand, the aetiology of the stroke remains unknown in approximately 20-25% of patients admitted due to ischaemic stroke. ... ...

    Abstract Introduction and objectives: Advanced interatrial block has been linked with atrial fibrillation (AF) (Bayes syndrome). On the other hand, the aetiology of the stroke remains unknown in approximately 20-25% of patients admitted due to ischaemic stroke. The aim of this study was to evaluate whether advanced interatrial block and CHADS2-VASC scale is linked to AF in patients admitted due to ischaemic stroke without previous AF history.
    Methods: A prospective analysis of consecutive in-hospital patients admitted with ischemic stroke between January/2018 and April/2019 in a stroke hospital was performed. Patients had to be in sinus rhythm at admission and without previous history of AF/atrial flutter. During follow up patients receive the usual care.
    Results: A total of 236 patients were included. The median follow-up was 540 days (407-695). 19 patients (8.1%) had advanced interatrial block at admission. Advanced interatrial block was associated with the diagnosis of AF during follow up (5 (26.3%) Vs 21 (9.7%) p=0.027). A CHADS2-VASC score>4 at admission was also associated with AF diagnosis during follow up (23(14.6%) vs 3(3.9%) p=0.009).
    Conclusion: This study confirms the association of advanced interatrial block and CHADS2-VASC>4 at admission with the diagnosis of AF during follow up in patients with ischemic stroke. This association could have important implications in patients with ischemic stroke who present advanced interatrial block and without previous history of AF.
    MeSH term(s) Atrial Fibrillation/complications ; Brain Ischemia/diagnosis ; Brain Ischemia/etiology ; Cohort Studies ; Humans ; Interatrial Block/complications ; Ischemic Stroke/diagnosis ; Ischemic Stroke/etiology ; Prospective Studies ; Risk Assessment ; Risk Factors
    Language Spanish
    Publishing date 2022-01-14
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2021.11.012
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