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  1. Book: Maxillofacial reconstruction

    Louis, Patrick J.

    (Oral and maxillofacial surgery clinics of North America ; 25,2)

    2013  

    Author's details ed. Patrick J. Louis
    Series title Oral and maxillofacial surgery clinics of North America ; 25,2
    Collection
    Language English
    Size XI S., S. 106 - 339 : zahlr. Ill.
    Publisher Elsevier
    Publishing place New York, NY u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017680409
    ISBN 978-1-4557-7130-1 ; 1-4557-7130-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 665 -25,2- verfügbar in Königswinter Königswinter

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  2. Article ; Online: Networked collective microbiomes and the rise of subcellular 'units of life'.

    Haraoui, Louis-Patrick

    Trends in microbiology

    2021  Volume 30, Issue 2, Page(s) 112–119

    Abstract: Microbiomes are generally conceived of as one element of a pair - their partner being the habitat they occupy. I call this common scientific practice 'pair-thinking'. Research into antimicrobial resistance and its underlying anthropogenic drivers ... ...

    Abstract Microbiomes are generally conceived of as one element of a pair - their partner being the habitat they occupy. I call this common scientific practice 'pair-thinking'. Research into antimicrobial resistance and its underlying anthropogenic drivers highlights the growing footprint occupied by mobile genetic elements (MGEs). Furthermore, these MGEs are known to circulate widely between microbiomes. Using a pluralistic framework anchored within a processual microbial ontology, these observations point to a reframing of microbiomes as networked and collective, thus challenging pair-thinking. Such a shift has implications for the future of microbiome research, from conceptual and methodological perspectives, and exposes the impacts of anthropogenic forces on the evolution of microbiomes and the functions they carry out.
    MeSH term(s) Microbiota/genetics
    Language English
    Publishing date 2021-10-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1158963-2
    ISSN 1878-4380 ; 0966-842X
    ISSN (online) 1878-4380
    ISSN 0966-842X
    DOI 10.1016/j.tim.2021.09.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3738: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: The Microbiome and Infectious Diseases.

    Haraoui, Louis-Patrick / Blaser, Martin J

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2023  Volume 77, Issue Suppl 6, Page(s) S441–S446

    Abstract: Our perception of microbes has considerably changed since the recognition of their pathogenic potential in the 19th century. The discovery of antibiotics and their subsequent widespread adoption have substantially altered the landscape of medicine, ... ...

    Abstract Our perception of microbes has considerably changed since the recognition of their pathogenic potential in the 19th century. The discovery of antibiotics and their subsequent widespread adoption have substantially altered the landscape of medicine, providing us with treatment options for many infectious diseases and enabling the deployment of previously risky interventions (eg, surgical procedures and chemotherapy), while also leading to the rise of AMR. The latter is commonly viewed as the predominant downside of antibiotic use. However, with the increasing recognition that all metazoan organisms rely on a community of microbes (the microbiota) for normal development and for most physiologic processes, the negative impacts of antibiotic use now extend well beyond AMR. Using the iceberg as a metaphor, we argue that the effects of antibiotics on AMR represent the tip of the iceberg, with much greater repercussions stemming from their role in the rise of so-called noncommunicable diseases (including obesity, diabetes, allergic and autoimmune diseases, neurodevelopmental disorders, and certain cancers). We highlight some of the emerging science around the intersection of the microbiome, antibiotic use, and health (including biological costs and future therapeutic avenues), and we advocate a more nuanced approach in evaluating the impacts of proposed antibiotic use, especially in the setting of preexposure and postexposure prophylaxis.
    MeSH term(s) Humans ; Animals ; Microbiota ; Anti-Bacterial Agents/therapeutic use ; Communicable Diseases/drug therapy ; Hypersensitivity ; Obesity
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-12-05
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciad577
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1505: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MO 480: Show issues

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  4. Article: Networked collective microbiomes and the rise of subcellular 'units of life'

    Haraoui, Louis-Patrick

    Trends in microbiology. 2022 Feb., v. 30, no. 2

    2022  

    Abstract: Microbiomes are generally conceived of as one element of a pair – their partner being the habitat they occupy. I call this common scientific practice 'pair-thinking'. Research into antimicrobial resistance and its underlying anthropogenic drivers ... ...

    Abstract Microbiomes are generally conceived of as one element of a pair – their partner being the habitat they occupy. I call this common scientific practice 'pair-thinking'. Research into antimicrobial resistance and its underlying anthropogenic drivers highlights the growing footprint occupied by mobile genetic elements (MGEs). Furthermore, these MGEs are known to circulate widely between microbiomes. Using a pluralistic framework anchored within a processual microbial ontology, these observations point to a reframing of microbiomes as networked and collective, thus challenging pair-thinking. Such a shift has implications for the future of microbiome research, from conceptual and methodological perspectives, and exposes the impacts of anthropogenic forces on the evolution of microbiomes and the functions they carry out.
    Keywords antibiotic resistance ; evolution ; habitats ; microbiology ; microbiome
    Language English
    Dates of publication 2022-02
    Size p. 112-119.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 1158963-2
    ISSN 1878-4380 ; 0966-842X
    ISSN (online) 1878-4380
    ISSN 0966-842X
    DOI 10.1016/j.tim.2021.09.011
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 2005/714: Show issues

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  5. Article ; Online: Complications of Dentoalveolar Surgery.

    Louis, Patrick J

    Oral and maxillofacial surgery clinics of North America

    2020  Volume 32, Issue 4, Page(s) 649–674

    Abstract: This article explores how to prevent and manage complications of dentoalveolar surgery. Many complications are avoidable. Surgical skills and knowledge of anatomy play an important role in prevention of complications. Prevention starts with detailed ... ...

    Abstract This article explores how to prevent and manage complications of dentoalveolar surgery. Many complications are avoidable. Surgical skills and knowledge of anatomy play an important role in prevention of complications. Prevention starts with detailed history and physical examination of the patient. Key to perioperative management of patients is risk assessment. Without a proper history and physical examination, the clinician is unable to assess the risk of performing surgery and anesthesia for each patient. Some illnesses and medications increase the risk of complications. The following complications are discussed: alveolar osteitis, displacement, fracture, hemorrhage, infection, nonhealing wound, oroantral communication, swelling, and trismus.
    MeSH term(s) Anesthesia, Dental ; Edema ; Humans ; Postoperative Complications/prevention & control ; Risk Assessment
    Language English
    Publishing date 2020-09-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1316546-x
    ISSN 1558-1365 ; 1042-3699
    ISSN (online) 1558-1365
    ISSN 1042-3699
    DOI 10.1016/j.coms.2020.07.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Se 665: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Earliest observation of the tetracycline destructase

    Grenier, Frédéric / Lévesque, Simon / Rodrigue, Sébastien / Haraoui, Louis-Patrick

    Microbiology spectrum

    2024  Volume 12, Issue 4, Page(s) e0332723

    Abstract: Tigecycline is an antibiotic of last resort for infections with carbapenem-resistant : Importance: We present the earliest observation of ... ...

    Abstract Tigecycline is an antibiotic of last resort for infections with carbapenem-resistant
    Importance: We present the earliest observation of a
    MeSH term(s) Tigecycline/pharmacology ; Microbial Sensitivity Tests ; Anti-Bacterial Agents/pharmacology ; Tetracycline/pharmacology ; Plasmids ; Carbapenems
    Chemical Substances Tigecycline (70JE2N95KR) ; Anti-Bacterial Agents ; Tetracycline (F8VB5M810T) ; Carbapenems
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.03327-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The evosystem: A centerpiece for evolutionary studies.

    Papale, François / Not, Fabrice / Bapteste, Éric / Haraoui, Louis-Patrick

    BioEssays : news and reviews in molecular, cellular and developmental biology

    2024  Volume 46, Issue 4, Page(s) e2300169

    Abstract: In this paper, we redefine the target of evolutionary explanations by proposing the "evosystem" as an alternative to populations, lineages and species. Evosystems account for changes in the distribution of heritable variation within individual Darwinian ... ...

    Abstract In this paper, we redefine the target of evolutionary explanations by proposing the "evosystem" as an alternative to populations, lineages and species. Evosystems account for changes in the distribution of heritable variation within individual Darwinian populations (evolution by natural selection, drift, or constructive neutral evolution), but also for changes in the networks of interactions within or between Darwinian populations and changes in the abiotic environment (whether these changes are caused by the organic entities or not). The evosystem can thereby become a centerpiece for a redefined evolutionary science, that is, evolutionary studies, that apprehends through a single framework the variety of evolutionary processes that lie at various scales. To illustrate the importance of this broadened perspective on evolution, we use a case of antimicrobial resistance evolution: the spread of the bla
    MeSH term(s) Biological Evolution ; Selection, Genetic
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 50140-2
    ISSN 1521-1878 ; 0265-9247
    ISSN (online) 1521-1878
    ISSN 0265-9247
    DOI 10.1002/bies.202300169
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2024: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Antimicrobial-Resistant Infections after Turkey/Syria Earthquakes, 2023.

    Rizk, Anthony / Abou Fayad, Antoine / Haraoui, Louis-Patrick

    Emerging infectious diseases

    2023  Volume 29, Issue 6, Page(s) 1273–1275

    Abstract: Increased rates of multidrug-resistant microbes have been reported after earthquakes. After the 2023 earthquakes in Turkey and Syria, the number of associated highly drug-resistant pathogens and nosocomial transmission will probably surge in hospitals ... ...

    Abstract Increased rates of multidrug-resistant microbes have been reported after earthquakes. After the 2023 earthquakes in Turkey and Syria, the number of associated highly drug-resistant pathogens and nosocomial transmission will probably surge in hospitals treating injured patients. It is not too late to act to prevent antimicrobial-resistant infections from compounding these tragedies.
    MeSH term(s) Humans ; Turkey/epidemiology ; Syria/epidemiology ; Earthquakes ; Anti-Infective Agents ; Hospitals ; Anti-Bacterial Agents/pharmacology ; Drug Resistance, Bacterial
    Chemical Substances Anti-Infective Agents ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-04-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2906.230316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4778: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: A cohort of cancer patients with no reported cases of SARS-CoV-2 infection

    Marc Henry / Mireille Summa / Louis Patrick / Laurent Schwartz

    Substantia, Vol 4, Iss

    the possible preventive role of Methylene Blue

    2020  Volume 1

    Abstract: We report the case of a cohort of 2500 French patients treated among others with methylene blue for cancer care. During the COVID-19 epidemics none of them developed influenza-like illness. Albeit this lack of infection might be by chance alone, it is ... ...

    Abstract We report the case of a cohort of 2500 French patients treated among others with methylene blue for cancer care. During the COVID-19 epidemics none of them developed influenza-like illness. Albeit this lack of infection might be by chance alone, it is possible that methylene blue might have a preventive effect for COVID-19 infection. This is in line with the antiviral activity of Chloroquine, a Methylene blue derivative. Both Chloroquine and Methylene blue have strong antiviral and anti- inflammatory properties probably linked to the change in intracellular pH and redox state.
    Keywords COVID-19 ; cancer ; methylene blue ; metabolic treatment ; History (General) and history of Europe ; D ; Chemistry ; QD1-999 ; covid19
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher Firenze University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: EMERGING PATTERNS IN THE RESISTANCE TO THE MEDICALIZATION OF BIRTH IN NORTH AMERICA

    Gillian Morantz-Ornstein / Louis-Patrick Haraoui

    McGill Journal of Medicine, Vol 7, Iss

    2020  Volume 1

    Abstract: ... N/ ... ...

    Abstract N/A
    Keywords resistance ; medicalization ; birth ; Medicine ; R
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher McGill University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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