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  1. Article ; Online: Use of abatacept in steroid refractory, immune checkpoint-induced myocarditis.

    Kalapurackal Mathai, Vinod / Black, Allison / Lovibond, Sam / Binny, Simon / Lipton, Jonathan / Moldovan, Cristina

    Internal medicine journal

    2021  Volume 51, Issue 11, Page(s) 1971–1972

    MeSH term(s) Abatacept ; Humans ; Myocarditis/chemically induced ; Myocarditis/drug therapy ; Nivolumab ; Steroids
    Chemical Substances Steroids ; Nivolumab (31YO63LBSN) ; Abatacept (7D0YB67S97)
    Language English
    Publishing date 2021-11-19
    Publishing country Australia
    Document type Letter
    ZDB-ID 2045436-3
    ISSN 1445-5994 ; 1444-0903
    ISSN (online) 1445-5994
    ISSN 1444-0903
    DOI 10.1111/imj.15566
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Miniaturized implantable cardiac monitor with a long sensing vector (BIOMONITOR III): Insertion procedure assessment, sensing performance, and home monitoring transmission success.

    Mariani, Justin A / Weerasooriya, Rukshen / van den Brink, Olivier / Mohamed, Uwais / Gould, Paul A / Pathak, Rajeev K / Lin, Tina / Conradie, Andre / Illes, Peter / Pavia, Stephen / Rajamani, Kushwin / Lovibond, Sam / Matthews, Ian / DiFiore, David / Arumugam, Deepak / Schrader, Jürgen / Lau, Dennis H

    Journal of electrocardiology

    2020  Volume 60, Page(s) 118–125

    Abstract: Background: Implantable Cardiac Monitors (ICMs) are used for long-term monitoring of arrhythmias. BIOMONITOR III is a novel ICM with a miniaturized profile, long sensing vector due to a flexible antenna, simplified implantation with a dedicated ... ...

    Abstract Background: Implantable Cardiac Monitors (ICMs) are used for long-term monitoring of arrhythmias. BIOMONITOR III is a novel ICM with a miniaturized profile, long sensing vector due to a flexible antenna, simplified implantation with a dedicated insertion tool for pocket formation and ICM placement in a single step, and daily automatic Home Monitoring (HM) function.
    Methods: In 47 patients undergoing BIOMONITOR III insertion for any ICM indication, 16 investigators at 10 Australian sites assessed handling characteristics of the insertion tool, R-wave amplitudes, noise burden, P-wave visibility, and HM transmission success. Patients were followed for 1 month.
    Results: All 47 attempted insertions were successful. Median time from skin incision to removal of the insertion tool after ICM insertion was 39 s (IQR 19-65) and to wound closure and cleaning was 4.7 min (IQR 3.5-7.8). All aspects of the insertion tool were rated as "good" or "excellent" in ≥97.9% and "fair" in ≤2.1% of patients, except for "force needed for tunnelling" (91.5% good/excellent, 8.5% fair). Based on HM data, R-waves in the first month were stable at 0.70 ± 0.37 mV. Median noise burden (disabling automatic rhythm evaluation) was 0.19% (IQR 0.00-0.93), equivalent to 2.7 min (IQR 0.0-13.4) per day. In HM-transmitted ECG strips with regular sinus rhythm, P-waves were visible in 89 ± 24% of heart cycles. Patient-individual automatic Home Monitoring transmission success was 98.0% ± 5.5%.
    Conclusions: The novel ICM performed well in all aspects studied, including fast insertion, reliable R-wave sensing, good P-wave visibility, and highly successful HM transmissions.
    MeSH term(s) Arrhythmias, Cardiac/diagnosis ; Australia ; Electrocardiography ; Electrocardiography, Ambulatory ; Humans
    Language English
    Publishing date 2020-04-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 410286-1
    ISSN 1532-8430 ; 0022-0736
    ISSN (online) 1532-8430
    ISSN 0022-0736
    DOI 10.1016/j.jelectrocard.2020.04.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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