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  1. Article ; Online: Comparison of Quality of Life in Vestibular Schwannoma Patients Managed with Observation, Radiotherapy or Microsurgery.

    Ball, Jessica F / Low, Jacob C M / Kasbekar, Anand V / Lesser, Tristram H

    The Journal of laryngology and otology

    2024  , Page(s) 1–24

    Language English
    Publishing date 2024-04-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 218299-3
    ISSN 1748-5460 ; 0022-2151
    ISSN (online) 1748-5460
    ISSN 0022-2151
    DOI 10.1017/S0022215124000471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Revealing Hearing Loss: A Survey of How People Verbally Disclose Their Hearing Loss.

    West, Jessica S / Low, Jacob C M / Stankovic, Konstantina M

    Ear and hearing

    2015  Volume 37, Issue 2, Page(s) 194–205

    Abstract: Objective: Hearing loss is the most common sensory deficit and congenital anomaly, yet the decision-making processes involved in disclosing hearing loss have been little studied. To address this issue, we have explored the phrases that adults with ... ...

    Abstract Objective: Hearing loss is the most common sensory deficit and congenital anomaly, yet the decision-making processes involved in disclosing hearing loss have been little studied. To address this issue, we have explored the phrases that adults with hearing loss use to disclose their hearing loss.
    Design: Since self-disclosure research has not focused on hearing loss-specific issues, we created a 15-question survey about verbally disclosing hearing loss. English speaking adults (>18 years old) with hearing loss of any etiology were recruited from otology clinics in a major referral hospital. Three hundred and thirty-seven participants completed the survey instrument. Participants' phrase(s) used to tell people they have hearing loss were compared across objective characteristics (age; sex; type, degree, and laterality of hearing loss; word recognition scores) and self-reported characteristics (degree of hearing loss; age of onset and years lived with hearing loss; use of technology; hearing handicap score).
    Results: Participants' responses revealed three strategies to address hearing loss: Multipurpose disclosure (phrases that disclose hearing loss and provide information to facilitate communication), Basic disclosure (phrases that disclose hearing loss through the term, a label, or details about the condition), or nondisclosure (phrases that do not disclose hearing loss). Variables were compared between patients who used and who did not use each disclosure strategy using χ or Wilcoxon rank sum tests. Multipurpose disclosers were mostly female (p = 0.002); had experienced reactions of help, support, and accommodation after disclosing (p = 0.008); and had experienced reactions of being overly helpful after disclosing (p=0.039). Basic disclosers were predominantly male (p = 0.004); reported feeling somewhat more comfortable disclosing their hearing loss over time (p = 0.009); had not experienced reactions of being treated unfairly or discriminated against (p = 0.021); and were diagnosed with mixed hearing loss (p = 0.004). Nondisclosers tended not to disclose in a group setting (p = 0.002) and were diagnosed with bilateral hearing loss (p = 0.005). In addition, all of the variables were examined to build logistic regression models to predict the use of each disclosure strategy.
    Conclusions: Our results reveal three simple strategies for verbally addressing hearing loss that can be used in a variety of contexts. We recommend educating people with hearing loss about these strategies-this could improve the experience of disclosing hearing loss, and could educate society at large about how to interact with those who have a hearing loss.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Communication ; Decision Making ; Female ; Hearing Loss ; Humans ; Logistic Models ; Male ; Middle Aged ; Self Disclosure ; Severity of Illness Index ; Surveys and Questionnaires ; Young Adult
    Language English
    Publishing date 2015-10-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 603093-2
    ISSN 1538-4667 ; 0196-0202
    ISSN (online) 1538-4667
    ISSN 0196-0202
    DOI 10.1097/AUD.0000000000000238
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Early versus late readmission of subarachnoid haemorrhage patients into neurocritical care.

    Low, Jacob C M / Welbourne, Jessie / McMillan, Helen / Whitfield, Peter C

    British journal of neurosurgery

    2016  Volume 30, Issue 5, Page(s) 545–548

    Abstract: Introduction: Subarachnoid haemorrhage (SAH) patients will typically require monitoring in a specialised Neurocritical Care Unit (NCCU) regardless of the primary treatment modality. Once discharged from NCCU, readmission within 48 h is regarded as a " ... ...

    Abstract Introduction: Subarachnoid haemorrhage (SAH) patients will typically require monitoring in a specialised Neurocritical Care Unit (NCCU) regardless of the primary treatment modality. Once discharged from NCCU, readmission within 48 h is regarded as a "failed" discharge. The aims of this study are to (1) Evaluate the readmission rate of SAH patients into NCCU, (2) Identify the indications for readmission, (3) Analyse clinical parameters on discharge between patients readmitted early and late.
    Materials and methods: Retrospective observational study of the Intensive Care National Audit and Research Centre (ICNARC) database of patients from our unit diagnosed with SAH from January 2009-December 2014, who were readmitted into NCCU. Demographic data, World Federation of Neurosurgical Societies (WFNS) grade, Fisher grade, length of initial and subsequent NCCU stay, time of readmission, indication for readmission, and mortality rate data were collected. Patients were categorised by early (<48 h) and late (>48 h) readmission, and their clinical parameters on NCCU discharge were statistically analysed.
    Results: Five hundred and seventy-five SAH patients were admitted into NCCU, of which 49 patients (9%) were readmitted after discharge to ward-level care. The mean age of readmitted patients was 64.1 ± 11.6 years old. The most common indications were delayed cerebral ischaemia (DCI) (50%) and infection (19%). Readmitted SAH patients were typically WFNS grade I-II (n = 22) and Fisher grade III-IV (n = 44). 17 (35%) patients were readmitted early, and were older (p = 0.0049) with a lower GCS (p = 0.0077) compared to patients readmitted later. White cell count and C-reactive protein were higher in patients readmitted early, but did not reach statistical significance (p = 0.09, p = 0.07).
    Conclusion: DCI and infection were the most common indications for NCCU readmission in SAH patients. "Failed" discharged patients from NCCU are typically older with a lower GCS than patients readmitted after 48 h, and therefore clinicians should be more cautious in discharging these patients prematurely.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Brain Ischemia/etiology ; Brain Ischemia/therapy ; C-Reactive Protein/analysis ; Critical Care/organization & administration ; Female ; Glasgow Coma Scale ; Hospital Mortality ; Humans ; Infection/etiology ; Infection/therapy ; Length of Stay ; Leukocyte Count ; Male ; Middle Aged ; Patient Readmission ; Retrospective Studies ; Subarachnoid Hemorrhage/mortality ; Subarachnoid Hemorrhage/surgery ; Treatment Failure ; United Kingdom
    Chemical Substances C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2016-10
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 639029-8
    ISSN 1360-046X ; 0268-8697
    ISSN (online) 1360-046X
    ISSN 0268-8697
    DOI 10.1080/02688697.2016.1199782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Quantitative polarized light microscopy of human cochlear sections.

    Low, Jacob C M / Ober, Thomas J / McKinley, Gareth H / Stankovic, Konstantina M

    Biomedical optics express

    2015  Volume 6, Issue 2, Page(s) 599–606

    Abstract: Dysfunction of the inner ear is the most common cause of sensorineural hearing loss, which is the most common sensory deficit worldwide. Conventional imaging modalities are unable to depict the microanatomy of the human inner ear, hence the need to ... ...

    Abstract Dysfunction of the inner ear is the most common cause of sensorineural hearing loss, which is the most common sensory deficit worldwide. Conventional imaging modalities are unable to depict the microanatomy of the human inner ear, hence the need to explore novel imaging modalities. We provide the first characterization of the polarization dependent optical properties of human cochlear sections using quantitative polarized light microscopy (qPLM). Eight pediatric cadaveric cochlear sections, aged 0 (term) to 24 months, were selected from the US National Temporal Bone Registry, imaged with qPLM and analyzed using Image J. Retardance of the bony otic capsule and basilar membrane were substantially higher than that of the stria vascularis, spiral ganglion neurons, organ of Corti and spiral ligament across the half turns of the spiraling cochlea. qPLM provides quantitative information about the human inner ear, and awaits future exploration in vivo.
    Language English
    Publishing date 2015-01-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2572216-5
    ISSN 2156-7085
    ISSN 2156-7085
    DOI 10.1364/BOE.6.000599
    Database MEDical Literature Analysis and Retrieval System OnLINE

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