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  1. Article ; Online: LAPAROSCOPIC SLEEVE GASTRECTOMY VERSUS LAPAROSCOPIC ROUX-EN-Y GASTRIC BYPASS FOR WEIGHT LOSS IN OBESE PATIENTS: WHICH IS MORE EFFECTIVE? A SYSTEMATIC REVIEW AND META-ANALYSIS.

    García-Honores, Laura / Caballero-Alvarado, Jose / Bustamante-Cabrejos, Alexander / Lozano-Peralta, Katherine / Zavaleta-Corvera, Carlos

    Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery

    2023  Volume 36, Page(s) e1782

    Abstract: Background: Bariatric surgery is the most effective option to reduce weight in morbid obesity patients. The techniques most employed are the restrictive surgery laparoscopic sleeve gastrectomy (LSG), surgical procedures of intestinal malabsorption, and ... ...

    Abstract Background: Bariatric surgery is the most effective option to reduce weight in morbid obesity patients. The techniques most employed are the restrictive surgery laparoscopic sleeve gastrectomy (LSG), surgical procedures of intestinal malabsorption, and both types (restrictive and intestinal malabsorption) such as the Roux-en-Y laparoscopic gastric bypass (RYLGB).
    Aims: To determine if LSG is more effective than RYLGB for weight loss.
    Methods: A systematic review and meta-analysis was carried out, including five clinical trials and sixteen cohorts comparing LSG versus RYLGB in weight loss and secondary outcomes: resolution of comorbidities, postoperative complications, operative time, hospital stay, and improvement in quality of life.
    Results: Excess weight loss was 10.2% (mean difference [MD] 10.2; 95%CI -10.14; -9.90) higher in patients undergoing LSG than in patients submitted to RYLGB. Diabetes mellitus type 2 was resolved in 17% (relative risk [RR] 0.83; 95%CI 0.77-0.90) of cases, more significantly after LSG, arterial hypertension in 23% (RR 0.77; 95%CI 0.69-0.84), and dyslipidemia in 17% (RR 0.83; 95%CI 0.77-0.90). Postoperative complications were 73% higher in patients undergoing RYLGB (MD 0.73; 95%CI 0.63-0.83). The operative time was 35.76 minutes shorter in the LSG (MD -35.76; 95%CI -37.28; -34.24). Finally, the quality of life improved more in patients operated by LSG (MD 0.37; 95%CI -0.48; -0.26).
    Conclusions: The study demonstrated that LSG could be more effective than RYLGB in reducing the percentage of excess weight, comorbidities, postoperative complications, operative time, hospital stay, and in improving quality of life.
    MeSH term(s) Humans ; Gastric Bypass/methods ; Quality of Life ; Obesity, Morbid/surgery ; Obesity, Morbid/complications ; Laparoscopy/methods ; Gastrectomy/methods ; Weight Loss ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Treatment Outcome
    Language English
    Publishing date 2023-12-08
    Publishing country Brazil
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ISSN 2317-6326
    ISSN (online) 2317-6326
    DOI 10.1590/0102-672020230064e1782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Post-COVID cholangiopathy: A narrative review.

    Caballero-Alvarado, José / Zavaleta Corvera, Carlos / Merino Bacilio, Bryan / Ruiz Caballero, Clara / Lozano-Peralta, Katherine

    Gastroenterologia y hepatologia

    2022  Volume 46, Issue 6, Page(s) 474–482

    Abstract: Since the spread of the first cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection much progress has been made in understanding the disease process. However, we are still facing the complications of coronavirus disease 19 ( ... ...

    Abstract Since the spread of the first cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection much progress has been made in understanding the disease process. However, we are still facing the complications of coronavirus disease 19 (COVID-19). Multiple sequelae may appear as a consequence of acute infection. This set of entities called post-COVID-19 syndrome involves a wide variety of new, recurrent or persistent symptoms grouped together as a consequence of the acute disease process. One of those that has attracted the most attention is the liver and bile duct involvement called post-COVID-19 cholangiopathy. This is characterized by elevation of liver markers such as alkaline phosphatase, bilirubin and transaminases as well as alterations in the bile ducts in imaging studies. Thus, a narrative review of the cases reported until the end of 2021 was carried out. From the findings found, we concluded that patients who have had COVID-19 or during the process have required hospitalization should remain under follow-up for at least 6 months by a multidisciplinary team.
    MeSH term(s) Humans ; Cholangitis, Sclerosing/diagnosis ; Post-Acute COVID-19 Syndrome ; COVID-19/complications ; SARS-CoV-2 ; Bile Ducts
    Language Spanish
    Publishing date 2022-09-27
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 632502-6
    ISSN 0210-5705
    ISSN 0210-5705
    DOI 10.1016/j.gastrohep.2022.09.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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