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Article ; Online: Inorganic Hydrogel Based on Low-Dimensional Nanomaterials.

Lu, Bing / Cheng, Huhu / Qu, Liangti

ACS nano

2024 Volume 18, Issue 4, Page(s) 2730–2749

Abstract: Composed of three-dimensional (3D) nanoscale inorganic bones and up to 99% water, inorganic hydrogels have attracted much attention and undergone significant growth in recent years. The basic units of inorganic hydrogels could be metal nanoparticles, ... ...

Abstract	Composed of three-dimensional (3D) nanoscale inorganic bones and up to 99% water, inorganic hydrogels have attracted much attention and undergone significant growth in recent years. The basic units of inorganic hydrogels could be metal nanoparticles, metal nanowires, SiO
Language	English
Publishing date	2024-01-14
Publishing country	United States
Document type	Journal Article ; Review
ISSN	1936-086X
ISSN (online)	1936-086X
DOI	10.1021/acsnano.3c11262
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: The Casimir effect in topological matter

Lu, Bing-Sui

2021

Abstract: We give an overview of the work done during the past ten years on the Casimir interaction in electronic topological materials, our focus being solids which possess surface or bulk electronic band structures with nontrivial topologies, which can be ... ...

Abstract	We give an overview of the work done during the past ten years on the Casimir interaction in electronic topological materials, our focus being solids which possess surface or bulk electronic band structures with nontrivial topologies, which can be evinced through optical properties that are characterizable in terms of nonzero topological invariants. The examples we review are three-dimensional magnetic topological insulators, two-dimensional Chern insulators, graphene monolayers exhibiting the relativistic quantum Hall effect, and time reversal symmetry-broken Weyl semimetals, which are fascinating systems in the context of Casimir physics, firstly for the reason that they possess electromagnetic properties characterizable by axial vectors (because of time reversal symmetry breaking), and depending on the mutual orientation of a pair of such axial vectors, two systems can experience a repulsive Casimir-Lifshitz force even though they may be dielectrically identical. Secondly, the repulsion thus generated is potentially robust against weak disorder, as such repulsion is associated with a Hall conductivity which is topologically protected in the zero-frequency limit. Finally, the far-field low-temperature behavior of the Casimir force of such systems can provide signatures of topological quantization. Comment: 32 pages, 7 figures, and 2 tables
Keywords	Condensed Matter - Mesoscale and Nanoscale Physics ; Condensed Matter - Materials Science
Publishing date	2021-05-23
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Particle Swarm Algorithm and Its Application in Tourism Route Design and Optimization.

Lu, Bing / Zhou, Chunlei

Computational intelligence and neuroscience

2022 Volume 2022, Page(s) 6467086

Abstract: Most of the traditional tourism route planning algorithms only consider single-factor planning, that is, the influence of scenic spots on route planning. Particle swarm optimization algorithm is favored by many people because of its simple concept, easy ... ...

Abstract	Most of the traditional tourism route planning algorithms only consider single-factor planning, that is, the influence of scenic spots on route planning. Particle swarm optimization algorithm is favored by many people because of its simple concept, easy implementation, and good robustness. Aiming at this problem, this paper takes the actual geographic data as the research object of the tourism route problem and describes the model of the discrete particle swarm algorithm based on geographic coordinates to solve the tourism route problem, which is used to solve practical problems. In order to further improve the global search ability of the algorithm, a self-balancing mechanism is proposed, which makes the algorithm process simple and the algorithm performance improved. At the same time, multithread parallelism is adopted to improve the solution speed of the algorithm, which makes up for the deficiency of the parallelization research of the algorithm.
MeSH term(s)	Algorithms ; Humans ; Tourism
Language	English
Publishing date	2022-03-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	2388208-6
ISSN	1687-5273 ; 1687-5273
ISSN (online)	1687-5273
ISSN	1687-5273
DOI	10.1155/2022/6467086
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Article: Upadacitinib for refractory ulcerative colitis with primary nonresponse to infliximab and vedolizumab: A case report.

Xu, Xuan / Jiang, Jing-Wen / Lu, Bing-Yun / Li, Xia-Xi

World journal of clinical cases

2024 Volume 12, Issue 9, Page(s) 1685–1690

Abstract: Background: Many patients with ulcerative colitis (UC) do not respond well to, or tolerate conventional and biological therapies. There is currently no consensus on the treatment of refractory UC. Studies have demonstrated that the selective Janus ... ...

Abstract	Background: Many patients with ulcerative colitis (UC) do not respond well to, or tolerate conventional and biological therapies. There is currently no consensus on the treatment of refractory UC. Studies have demonstrated that the selective Janus kinase 1 inhibitor upadacitinib, a small-molecule drug, is effective and safe for treating UC. However, no studies have revealed that upadacitinib is effective in treating refractory UC with primary nonresponse to infliximab and vedolizumab. Case summary: We report the case of a 44-year-old male patient with a chief complaint of bloody diarrhoea with mucus and pus, in addition to dizziness. The patient had recurrent disease after receiving mesalazine, prednisone, azathioprine, infliximab and vedolizumab over four years. Based on the endoscopic findings and pathological biopsy, the patient was diagnosed with refractory UC. In particular, the patient showed primary nonresponse to infliximab and vedolizumab. Based on the patient's history and recurrent disease, we decided to administer upadacitinib. During hospitalisation, the patient was received upadacitinib under our guidance. Eight weeks after the initiation of upadacitinib treatment, the patient's symptoms and endoscopic findings improved significantly. No notable adverse reactions have been reported to date. Conclusion: Our case report suggests that upadacitinib may represent a valuable strategy for treating refractory UC with primary nonresponse.
Language	English
Publishing date	2024-02-19
Publishing country	United States
Document type	Case Reports
ISSN	2307-8960
ISSN	2307-8960
DOI	10.12998/wjcc.v12.i9.1685
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Article ; Online: Influence of mudstone on coal spontaneous combustion characteristics and oxidation kinetics analysis.

Zhang, Xun / Zou, Jiahui / Lu, Bing / Bai, Gang / Qiao, Ling

Scientific reports

2024 Volume 14, Issue 1, Page(s) 9744

Abstract: To explore the spontaneous combustion characteristics and hazards of the low-temperature oxidation (LTO) stage in the process of spontaneous combustion of coal and mudstone, the pore structure, spontaneous combustion characteristic parameters, and ... ...

Abstract	To explore the spontaneous combustion characteristics and hazards of the low-temperature oxidation (LTO) stage in the process of spontaneous combustion of coal and mudstone, the pore structure, spontaneous combustion characteristic parameters, and exothermic characteristics of coal and mudstone were tested and studied, and the oxidation kinetic parameters were calculated. The results show that mudstone has a larger specific surface area and pore volume than coal. From the fractal characteristics, the pore structure of mudstone is more complex than that of coal. According to the comparison of theoretical and actual gas generation and oxygen consumption rate curves, it is found that there is an interaction between coal and mudstone in the LTO process. With the increase of mudstone mass ratio, gas production, and its oxygen consumption rate increase. Among them, CM-4 (Coal:Mudstone = 1:1) has the highest exothermic intensity and the exothermic factor (A) and fire coefficient (K) increase with the increase of mudstone content. The apparent activation energy of the mudstone sample is lower than that of the raw coal, indicating that the sample after adding mudstone is more likely to have spontaneous combustion in the LTO stage.
Language	English
Publishing date	2024-04-28
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-59797-8
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Article ; Online: Numerical simulation study on the evolution law of mechanical properties of different metamorphic coals after heat treatment.

Zhang, Xun / Lai, Hongyu / Huang, Ge / Lu, Bing / Liang, Huimin

Scientific reports

2024 Volume 14, Issue 1, Page(s) 8171

Abstract: In order to study the effect of temperature on the structure and mechanical properties of coal with different metamorphic degree. Three coal samples with varying degrees of metamorphism were chosen for analysis. The discrete element software PFC2D is ... ...

Abstract	In order to study the effect of temperature on the structure and mechanical properties of coal with different metamorphic degree. Three coal samples with varying degrees of metamorphism were chosen for analysis. The discrete element software PFC2D is used to simulate the heat treatment and compression of coal. The findings indicate that during the heating process, low-order coal exhibits noticeable thermal cracks at an early stage, while thermal crack development in middle-order coal is concentrated in the later stages. In contrast, high-order coal demonstrates a more stable macroscopic structure. The strength and stiffness of low rank coal show the lowest value and decrease significantly within 135 °C. However, the strength and stiffness of medium rank coal decrease significantly after 135 °C. The changes of mechanical properties and damage modes of coal caused by thermal damage are often ignored, which may lead to the deviation of design and research results from the actual situation. Therefore, this study is of great significance to the prevention and control of coal mine disasters.
Language	English
Publishing date	2024-04-08
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-59051-1
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Article ; Online: Causal relationships between circulating inflammatory cytokines and diabetic neuropathy: A Mendelian Randomization study.

Wang, Zhaoxiang / Zhang, Li / Lu, Bing / Sun, Heping / Zhong, Shao

Cytokine

2024 Volume 177, Page(s) 156548

Abstract: Background: Emerging evidence suggests systemic inflammation as a critical mechanism underlying diabetic neuropathy. This study aimed to investigate the causal relationship between 41 circulating inflammatory cytokines and diabetic neuropathy.: ... ...

Abstract	Background: Emerging evidence suggests systemic inflammation as a critical mechanism underlying diabetic neuropathy. This study aimed to investigate the causal relationship between 41 circulating inflammatory cytokines and diabetic neuropathy. Methods: Summary statistics from previous Genome-Wide Association studies (GWAS) included pooled data on 41 inflammatory cytokines and diabetic neuropathy. A two-sample Mendelian Randomization (MR) design was employed, and the robustness of the results was confirmed through comprehensive sensitivity analyses. Results: Our study reveals that the linkage between increased levels of IFN_G (OR = 1.31, 95 %CI: 1.06-1.63; P = 0.014), IP_10 (OR = 1.18, 95 %CI: 1.01-1.36; P = 0.031) and an elevated risk of diabetic neuropathy. Conversely, higher levels of IL_9 (OR = 0.86, 95 %CI: 0.75-1.00; P = 0.048) and SCF (OR = 0.83, 95 %CI: 0.73-0.94; P = 0.003) are genetically determined to protect against diabetic neuropathy. Furthermore, the sensitivity analysis affirmed the results' dependability, revealing no heterogeneity or pleiotropy. Conclusion: Our MR research identified four upstream inflammatory cytokines implicated in diabetic neuropathy. Overall, these findings suggest the potential for innovative therapeutic strategies. Further large-scale cohort studies are required for validation.
MeSH term(s)	Humans ; Cytokines/genetics ; Diabetic Neuropathies/genetics ; Genome-Wide Association Study ; Mendelian Randomization Analysis ; Interferon-gamma ; Diabetes Mellitus
Chemical Substances	Cytokines ; Interferon-gamma (82115-62-6)
Language	English
Publishing date	2024-02-23
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1018055-2
ISSN	1096-0023 ; 1043-4666
ISSN (online)	1096-0023
ISSN	1043-4666
DOI	10.1016/j.cyto.2024.156548
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Article ; Online: Calibration Maintenance Application of Near-infrared Spectrometric Model in Food Analysis

Qiao, Lu / Mu, Yingchun / Lu, Bing / Tang, Xiuying

Food Reviews International. 2023 Apr. 03, v. 39, no. 3 p.1628-1644

2023

Abstract: Near-infrared (NIR) spectroscopy technique has been developed to objectively measure quality attributes for different food products in recent years. However, any change in measurement condition or instrumental response can result in performance decline ... ...

Abstract	Near-infrared (NIR) spectroscopy technique has been developed to objectively measure quality attributes for different food products in recent years. However, any change in measurement condition or instrumental response can result in performance decline of the multivariate calibration model. Thus, calibration maintenance is significant for widespread application of NIR technique in food analysis. Various maintenance approaches have been performed to improve the applicability of calibration model. This paper reviews common calibration maintenance methods based on different principles, and introduces multivariate statistical evaluations for model acceptance. Calibration maintenance applications in food quality analysis are presented to illustrate the capability of this approach for food quality prediction, which can improve the model applicability and prediction accuracy effectively. Further researches of calibration maintenance for different food quality parameters are needed to realize efficient and reliable application of NIR prediction in food industry.
Keywords	calibration ; food analysis ; food industry ; food quality ; models ; prediction ; spectroscopy ; NIR spectroscopy ; model maintenance ; calibration transfer
Language	English
Dates of publication	2023-0403
Size	p. 1628-1644.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	53834-6
ISSN	1525-6103 ; 8755-9129
ISSN (online)	1525-6103
ISSN	8755-9129
DOI	10.1080/87559129.2021.1935999
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: The design strategy for pillararene based active targeted drug delivery systems.

Lu, Bing / Xia, Jiachen / Huang, Yuying / Yao, Yong

Chemical communications (Cambridge, England)

2023 Volume 59, Issue 81, Page(s) 12091–12099

Abstract: Pillararenes have columnar architectures with electron-rich cavities to endow themselves with unique host-guest complexation capability. Easy structural modifiability facilitates them to be used in many applications. Currently, pillararene based drug ... ...

Abstract	Pillararenes have columnar architectures with electron-rich cavities to endow themselves with unique host-guest complexation capability. Easy structural modifiability facilitates them to be used in many applications. Currently, pillararene based drug delivery systems (DDSs) have been developed as a powerful tool for precise diagnosis and treatment of cancer. Various functional guest molecules could be integrated with pillararenes to construct nanomaterials for cancer chemotherapy, phototherapy and chemodynamic therapy. In order to improve cancer therapy efficacy, active targeted DDSs have become particularly important. Benefiting from the good host-guest properties and structural variability of pillararenes, tumor targeting groups could be easily introduced into pillararene based DDSs to realize precise drug delivery at tumor sites. In this feature article, we provide a comprehensive summary of the present design strategy for pillararene based active targeted DDSs, which can be classified into three types namely host-guest complexation, charge reversal and targeted group modified pillararenes. Some important examples are selected to for a detailed discussion on their respective strengths and weaknesses.
Language	English
Publishing date	2023-10-10
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1472881-3
ISSN	1364-548X ; 1359-7345 ; 0009-241X
ISSN (online)	1364-548X
ISSN	1359-7345 ; 0009-241X
DOI	10.1039/d3cc04021f
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Article ; Online: Dissecting the causal relationship between household income status and genetic susceptibility to cardiovascular-related diseases: Insights from bidirectional mendelian randomization study.

Zheng, Xifeng / Yang, Yu / Chen, Jianying / Lu, Bing

BMC public health

2023 Volume 23, Issue 1, Page(s) 749

Abstract: Objectives: Observational studies have revealed that socioeconomic status is associated with cardiovascular health. However, the potential causal effect remains unclear. Hence, we aimed to investigate the causal relationship between household income ... ...

Abstract	Objectives: Observational studies have revealed that socioeconomic status is associated with cardiovascular health. However, the potential causal effect remains unclear. Hence, we aimed to investigate the causal relationship between household income status and genetic susceptibility to cardiovascular-related diseases using a bidirectional Mendelian randomization (MR) study. Methods: An MR study based on a large-sample cohort of the European population from a publicly available genome-wide association study datasets was conducted using a random-effects inverse-variance weighting model as the main standard. Simultaneously, MR-Egger regression, weighted median, and maximum likelihood estimation were used as supplements. Sensitivity analysis, consisting of a heterogeneity test and horizontal pleiotropy test, was performed using Cochran's Q, MR-Egger intercept, and MR-PRESSO tests to ensure the reliability of the conclusion. Results: The results suggested that higher household income tended to lower the risk of genetic susceptibility to myocardial infarction (OR: 0.503, 95% CI = 0.405-0.625, P < 0.001), hypertension (OR: 0.667, 95% CI = 0.522-0.851, P = 0.001), coronary artery disease (OR: 0.674, 95% CI = 0.509-0.893, P = 0.005), type 2 diabetes (OR: 0.642, 95% CI = 0.464-0.889, P = 0.007), heart failure (OR: 0.825, 95% CI = 0.709-0.960, P = 0.013), and ischemic stroke (OR: 0.801, 95% CI = 0.662-0.968, P = 0.022). In contrast, no association was evident with atrial fibrillation (OR: 0.970, 95% CI = 0.767-1.226, P = 0.798). The reverse MR study suggested a potentially negative trend between heart failure and household income status. A sensitivity analysis verified the reliability of the results. Conclusions: The results revealed that the population with higher household income tended to have a lower risk of genetic susceptibility to myocardial infarction and hypertension.
MeSH term(s)	Humans ; Genetic Predisposition to Disease ; Diabetes Mellitus, Type 2 ; Genome-Wide Association Study ; Mendelian Randomization Analysis ; Reproducibility of Results ; Cardiovascular Diseases ; Heart Failure ; Hypertension ; Myocardial Infarction
Language	English
Publishing date	2023-04-24
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-023-15561-7
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