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  1. Article ; Online: Effects of Climate Change in Marine Ecosystems Based on the Spatiotemporal Age Structure of Top Predators

    Kuo-Wei Lan / Yan-Lun Wu / Lu-Chi Chen / Muhamad Naimullah / Tzu-Hsiang Lin

    Frontiers in Marine Science, Vol

    A Case Study of Bigeye Tuna in the Pacific Ocean

    2021  Volume 8

    Abstract: How top predators behave and are distributed depend on the conditions in their marine ecosystem through bottom−up forcing; this is because where and when these predators can feed and spawn are limited and change often. This study investigated how the ... ...

    Abstract How top predators behave and are distributed depend on the conditions in their marine ecosystem through bottom−up forcing; this is because where and when these predators can feed and spawn are limited and change often. This study investigated how the catch rates of immature and mature cohorts of bigeye tuna (BET) varied across space and time; this was achieved by analyzing data on the Taiwanese longline fishery in the western and central Pacific Ocean (WCPO). We also conducted a case study on the time series patterns of BET cohorts to explore the processes that underlie the bottom-up control of the pelagic ecosystem that are influenced by decadal climate events. Wavelet analysis results revealed crucial synchronous shifts in the connection between the pelagic ecosystems at low trophic levels in relation to the immature BET cohort. Many variables exhibited decreasing trends after 2004–2005, and we followed the Pacific Decadal Oscillation (PDO) as a bottom-up control regulator. The results indicated that low recruitment into the mature cohort occurs 3 years after a decrease in the immature cohort’s food stocks, as indicated by a 3-year lag in our results. This finding demonstrated that, by exploring the connection between low-trophic-level species and top predators at various life stages, we can better understand how climate change affects the distribution and abundance of predator fish.
    Keywords bottom-up forcing ; climate change ; bigeye tuna ; Pacific Decadal Oscillation ; spatiotemporal age structure ; marine ecosystem ; Science ; Q ; General. Including nature conservation ; geographical distribution ; QH1-199.5
    Subject code 333 ; 551
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Distribution and Catch Rate Characteristics of Narrow-Barred Spanish Mackerel (Scomberomorus commerson) in Relation to Oceanographic Factors in the Waters Around Taiwan

    Lu-Chi Chen / Jinn-Shing Weng / Muhamad Naimullah / Po-Yuan Hsiao / Chen-Te Tseng / Kuo-Wei Lan / Che-Chen Chuang

    Frontiers in Marine Science, Vol

    2021  Volume 8

    Abstract: This study investigated the relationship of the catch rates (CRs) of Spanish mackerel (Scomberomorus commerson) with oceanographic factors in the waters around Taiwan by using high-resolution fishery and environmental data for the period 2011–2016. The ... ...

    Abstract This study investigated the relationship of the catch rates (CRs) of Spanish mackerel (Scomberomorus commerson) with oceanographic factors in the waters around Taiwan by using high-resolution fishery and environmental data for the period 2011–2016. The investigation results revealed that trammel nets accounted for 69.79% of the total catch of S. commerson and were operated mostly in the Taiwan Strait (TS). We noted seasonal variations in the distribution of high CRs. These CRs were observed in the southwestern TS, including the waters along the southwestern coast of Taiwan and around the Penghu Islands, and extended to the Taiwan Bank during autumn; they increased in winter. To predict the spatial and temporal patterns of Spanish mackerel density and their relationship with oceanographic and spatiotemporal variables, generalized additive models were used. These models explained 48.4% of the total deviance, which was consistent with the assumed Gaussian distribution. Moreover, all variables examined were significant CR predictors (p < 0.05). Latitude and longitude were the key factors influencing the spatiotemporal distribution of S. commerson, and sea surface chlorophyll a concentration was a key oceanographic factor. Observing projected changes in El Niño/Southern Oscillation events for S. commerson revealed that CRs were higher and distributed further southward during La Niña events than during other events. We inferred that the S. commerson distribution gradually moved toward the southwest with the northeast monsoon, which was enhanced during La Niña in winter.
    Keywords catch rate ; Spanish mackerel ; generalized additive model ; fishing dynamic ; environmental factor ; climatic variability ; Science ; Q ; General. Including nature conservation ; geographical distribution ; QH1-199.5
    Subject code 551
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Evaluating a Suitable Aquaculture Site Selection Model for Cobia ( Rachycentron canadum ) during Extreme Events in the Inner Bay of the Penghu Islands, Taiwan

    Yan-Lun Wu / Ming-An Lee / Lu-Chi Chen / Jui-Wen Chan / Kuo-Wei Lan

    Remote Sensing, Vol 12, Iss 2689, p

    2020  Volume 2689

    Abstract: Despite numerous studies on the effect of a cold weather disaster on fisheries in 2008, no operational systems have been developed to monitor the threat of such an event to mariculturists in the Penghu Islands (PHI) region of Taiwan. The present study ... ...

    Abstract Despite numerous studies on the effect of a cold weather disaster on fisheries in 2008, no operational systems have been developed to monitor the threat of such an event to mariculturists in the Penghu Islands (PHI) region of Taiwan. The present study employed a suitable aquaculture site selection map of the inner bay of the PHI to reduce aquaculture losses and mortality rates of cobia ( Rachycentron canadum ) during extreme events. Daily marine environmental data, including sea surface temperature (SST), chlorophyll-a concentration (chl-a), and wind speed in the winter, were collected. An extreme event was defined as a period of over 11 days in a month of strong winds (>6 m/s). Four parameters in the PHI inner bay, including SST, cold-water intrusion days, chl-a, and offshore distance to the PHI coastline, were used to evaluate suitable aquaculture sites for cobia culture. The results indicated that La Niña events could not be used as a factor to detect cold-water intrusion events and select suitable aquaculture sites in the PHI. The evaluated suitable aquaculture site selection map, obtained using an arithmetic mean model and a geometric mean model, revealed that the avoidance sites during extreme events were concentrated in the northern and northwestern PHI. Suitable areas were concentrated in the southeastern areas. We further suggested that commercial cobia aquaculture operations in the PHI inner bay could be moved to the suitable sites in southeastern PHI during extreme events.
    Keywords cobia ; aquaculture site selection ; extreme events ; Penghu Islands ; Science ; Q
    Subject code 551
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Trophic Dynamics and Feeding Ecology of Skipjack Tuna ( Katsuwonus pelamis ) off Eastern and Western Taiwan

    Yun-Chen Chang / Wei-Chuan Chiang / Daniel J. Madigan / Fu-Yuan Tsai / Ching-Lung Chiang / Hung-Hung Hsu / Shiow-Mei Lin / Mei-Ying Zhuang / Ching-Ting Sun / Lu-Chi Chen / Sheng-Ping Wang

    Molecules, Vol 27, Iss 1073, p

    2022  Volume 1073

    Abstract: The skipjack tuna ( Katsuwonus pelamis ) is a mesopredator fish species with seasonal abundance in waters off Taiwan. Regional ecological and life-history information has been historically lacking for this species. In recent years, stable isotope ... ...

    Abstract The skipjack tuna ( Katsuwonus pelamis ) is a mesopredator fish species with seasonal abundance in waters off Taiwan. Regional ecological and life-history information has been historically lacking for this species. In recent years, stable isotope analysis (SIA) of carbon and nitrogen has been used to assess predator feeding ecology and broader ecosystem trophic dynamics. This study evaluated comparative skipjack feeding ecology in distinct regions off Taiwan, combining traditional stomach content analysis with SIA of individuals off western ( n = 43; 2020) and eastern ( n = 347; 2012–2014 and n = 167; 2020) Taiwan. The stomach content analysis showed the most important prey to be ponyfish ( Photopectoralis bindus ) in western Taiwan and epipelagic squids ( Myopsina spp.) and carangids ( Decapterus macrosoma ;) in eastern Taiwan from 2012 to 2014 and epipelagic carangids ( Decapterus spp.) and flying fishes ( Cheilopogon spp.) in eastern Taiwan in 2020, suggesting that the skipjack tuna is a generalist predator across regions. In contrast, time-integrated diet estimates from Bayesian mixing models indicated the importance of cephalopods and crustaceans as prey, potentially demonstrating more mesopelagic feeding in less productive waters during skipjack migrations outside the study regions. Skipjack off western Taiwan had a slightly higher estimated trophic position than in the waters off eastern Taiwan, potentially driven by the varying nutrient-driven pelagic food web structures. Skipjack SI values increased with body size off eastern Taiwan but not in western waters, suggesting that opportunistic predation can still result in different predator–prey size dynamics between regions.
    Keywords pelagic ; predator ; diet ; stable isotope analysis ; Bayesian mixing models ; Northwest Pacific ; Organic chemistry ; QD241-441
    Subject code 590
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Electroacupuncture induces differential effects between Yin and Yang: a study using cutaneous blood flow and temperature recordings of the hand's dorsum and palm.

    Lu, Chi-Chen / Jan, Ya-Min / Li, Tsai-Chung / Hsieh, Ching-Liang

    The American journal of Chinese medicine

    2009  Volume 37, Issue 4, Page(s) 639–645

    Abstract: The underlying theory of traditional Chinese Medicine (TCM) considers that Yin and Yang are in the opposition with each other and play different roles in physiological responses. Several studies have reported that electroacupuncture (EA) produces a ... ...

    Abstract The underlying theory of traditional Chinese Medicine (TCM) considers that Yin and Yang are in the opposition with each other and play different roles in physiological responses. Several studies have reported that electroacupuncture (EA) produces a greater effect than manual acupuncture (MA), and that the effect of EA is similar to transcutaneous electric nerve stimulation (TENS). Therefore, the purpose of the present study was to investigate the differences between Yin and Yang induced by acupuncture. A total of 20 healthy volunteers were studied. The cutaneous blood flow and temperature were recorded by a laser doppler perfusion and temperature monitoring system on the dorsum and palm of the right hand. Four sessions of sham acupuncture (SA), MA, 2 Hz EA, and 2 Hz TENS were bilaterally applied to Zusanli (ST36) and Shangjuxu (ST37) acupoints. Each of the subjects received four sessions in a random manner. The treatment interval was at least three days between sessions in order to prevent overlapping residual effects. Each of the four sessions was divided into pre-acupuncture period (BP), acupuncture period (AP), and post-acupuncture (PP) periods. Each treatment period was 15 min. Results indicated that the cutaneous blood flow recorded from the palm of the hand were greater than that recorded from the dorsum at the pre-acupuncture period; while the difference in the cutaneous temperature from the dorsum of the hand between AP and BP was greater in the 2 Hz EA session than in the SA and MA sessions. In conclusion, the results of the present study were consistent with the underlying theory of TCM that considers the fundamental differences between Yin and Yang.
    MeSH term(s) Acupuncture/methods ; Adult ; Analysis of Variance ; Blood Flow Velocity ; Electroacupuncture/methods ; Female ; Hand/physiology ; Humans ; Male ; Skin/blood supply ; Skin Temperature/physiology ; Transcutaneous Electric Nerve Stimulation/methods ; Yin-Yang ; Young Adult
    Language English
    Publishing date 2009
    Publishing country Singapore
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 193085-0
    ISSN 0192-415X ; 0090-2942
    ISSN 0192-415X ; 0090-2942
    DOI 10.1142/S0192415X09007120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Guizhi Fuling Wan as a Novel Agent for Intravesical Treatment for Bladder Cancer in a Mouse Model.

    Lu, Chi-Chen / Shen, Cheng-Huang / Chang, Chia-Bin / Hsieh, Hsiao-Yen / Wu, Jiann-Der / Tseng, Ling-Huei / Hwang, Dennis W / Chen, Syue-Yi / Wu, Shu-Fen / Chan, Michael W Y / Hsu, Cheng-Da

    Molecular medicine (Cambridge, Mass.)

    2016  Volume 22, Page(s) 64–73

    Abstract: Alternative intravesical agents are required to overcome the side effects currently associated with the treatment of bladder cancer. This study used an orthotopic bladder cancer mouse model to evaluate Guizhi Fuling Wan (GFW) as an intravesical agent. ... ...

    Abstract Alternative intravesical agents are required to overcome the side effects currently associated with the treatment of bladder cancer. This study used an orthotopic bladder cancer mouse model to evaluate Guizhi Fuling Wan (GFW) as an intravesical agent. The effects of GFW were compared with those of mitomycin-C (Mito-C) and bacille Calmette-Guérin (BCG). We began by evaluating the response of the mouse bladder cancer cell line MB49 to GFW treatment, with regard to cell viability, cell cycle progression and apoptosis. MB49 cells were subsequently implanted into the urothelial walls of the bladder in female C57BL/6 mice. The success of the model was confirmed by the appearance of hematuria and tumor growth in the bladder. Intravesical chemotherapy was administered in accordance with a published protocol.
    Language English
    Publishing date 2016-01-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1283676-x
    ISSN 1528-3658 ; 1076-1551
    ISSN (online) 1528-3658
    ISSN 1076-1551
    DOI 10.2119/molmed.2015.00085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The investigation of a traditional Chinese medicine, Guizhi Fuling Wan (GFW) as an intravesical therapeutic agent for urothelial carcinoma of the bladder.

    Lu, Chi-Chen / Lin, Mei-Yi / Chen, Syue-Yi / Shen, Cheng-Huang / Chen, Lih-Geeng / Hsieh, Hsiao-Yen / Chan, Michael W Y / Hsu, Cheng-Da

    BMC complementary and alternative medicine

    2013  Volume 13, Page(s) 44

    Abstract: Background: The high risk of recurrence faced by patients with bladder cancer has necessitated the administration of supplemental intravesical chemotherapy; however, such treatments often result in severe side effects. As a result, novel intravesical ... ...

    Abstract Background: The high risk of recurrence faced by patients with bladder cancer has necessitated the administration of supplemental intravesical chemotherapy; however, such treatments often result in severe side effects. As a result, novel intravesical agents with enhanced efficacy and minimal toxicity are urgently required for the treatment of bladder cancer.
    Methods: Guizhi Fuling Wan (GFW) is a traditional Chinese medicine shown to inhibit the growth of hepatocellular carcinoma. This study evaluated the growth inhibition of GFW using normal human urothelial cells and bladder cancer cells; the efficacy of GFW treatment was further compared with mitomycin C, epirubicin, and cisplatin. We also examined the progression of cell cycle and apoptosis in bladder cancer cells in response to GFW treatment. CCK-8 was employed to analyze cell viability and flow cytometry was used to study the cell cycle and apoptosis. The mechanisms underlying GFW-induced cell cycle arrest were determined by Western blot analysis.
    Results: Our data demonstrate the potent inhibitory effect of GFW in the proliferation of bladder cancer cell lines, BFTC 905 and TSGH 8301. GFW presented relatively high selectivity with regard to cancer cells and minimal toxicity to normal urothelial cells. Our results also demonstrate that GFW interferes with cell cycle progression through the activation of CHK2 and P21 and induces apoptosis in these bladder cancer cells.
    Conclusions: Our results provide experimental evidence to support GFW as a strong candidate for intravesicle chemotherapy against bladder cancer.
    MeSH term(s) Antineoplastic Agents/therapeutic use ; Antineoplastic Agents, Phytogenic/pharmacology ; Antineoplastic Agents, Phytogenic/therapeutic use ; Apoptosis/drug effects ; Carcinoma/drug therapy ; Carcinoma/metabolism ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Checkpoint Kinase 2 ; Cisplatin/therapeutic use ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Epirubicin/therapeutic use ; Humans ; Mitomycin/therapeutic use ; Phytotherapy ; Protein-Serine-Threonine Kinases/metabolism ; Sincalide ; Urinary Bladder/cytology ; Urinary Bladder/drug effects ; Urinary Bladder/metabolism ; Urinary Bladder Neoplasms/drug therapy ; Urinary Bladder Neoplasms/metabolism ; Urothelium/cytology ; Urothelium/drug effects
    Chemical Substances Antineoplastic Agents ; Antineoplastic Agents, Phytogenic ; CDKN1A protein, human ; Cyclin-Dependent Kinase Inhibitor p21 ; Drugs, Chinese Herbal ; guizhi-fuling ; Epirubicin (3Z8479ZZ5X) ; Mitomycin (50SG953SK6) ; Checkpoint Kinase 2 (EC 2.7.1.11) ; CHEK2 protein, human (EC 2.7.11.1) ; Protein-Serine-Threonine Kinases (EC 2.7.11.1) ; Sincalide (M03GIQ7Z6P) ; Cisplatin (Q20Q21Q62J)
    Language English
    Publishing date 2013-02-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2050429-9
    ISSN 1472-6882 ; 1472-6882
    ISSN (online) 1472-6882
    ISSN 1472-6882
    DOI 10.1186/1472-6882-13-44
    Database MEDical Literature Analysis and Retrieval System OnLINE

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