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  1. Article ; Online: Precision Synthesis of Polysarcosine via Controlled Ring-Opening Polymerization of

    Wang, Shuo / Lu, Ming-Yuan / Wan, Si-Kang / Lyu, Chun-Yan / Tian, Zi-You / Liu, Kai / Lu, Hua

    Journal of the American Chemical Society

    2024  Volume 146, Issue 8, Page(s) 5678–5692

    Abstract: The rapid and controlled synthesis of high-molecular-weight (HMW) polysarcosine (pSar), a potential polyethylene glycol (PEG) alternative, via the ring-opening polymerization (ROP) ... ...

    Abstract The rapid and controlled synthesis of high-molecular-weight (HMW) polysarcosine (pSar), a potential polyethylene glycol (PEG) alternative, via the ring-opening polymerization (ROP) of
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.3c14740
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Mechanisms associated with the depigmentation of brown eggshells: a review

    Lu, Ming-Yuan / Xu, Li / Qi, Guang-Hai / Zhang, Hai-Jun / Qiu, Kai / Wang, Jing / Wu, Shu-Geng

    Poultry science. 2021 Aug., v. 100, no. 8

    2021  

    Abstract: Eggshell color is an important shell quality trait that influences consumer preference. It is also of particular importance with respect to sexual signaling and the physiological and mechanical properties of shell pigment. Pigments include protoporphyrin ...

    Abstract Eggshell color is an important shell quality trait that influences consumer preference. It is also of particular importance with respect to sexual signaling and the physiological and mechanical properties of shell pigment. Pigments include protoporphyrin IX, biliverdin, and traces of biliverdin zinc chelates, with brown eggs being notably rich in protoporphyrin IX, the synthesis of which has a marked effect on the intensity of brown eggshell color. This pigment is initially synthesized in the eggshell gland within the oviduct of laying hens and is subsequently deposited throughout the cuticular and calcareous layers of brown eggshell. In this review, we describe the factors affecting brown eggshell color and potential targets for the regulation of pigment synthesis. Protoporphyrin IX synthesis might be compromised by synthetase-mediated pigment synthesis, the redox status of the female birds, and regulation of the nuclear transcription factors associated with δ-aminolevulinic acid synthetase1. We believe that this review will provide a valuable reference for those engaged in studying eggshell depigmentation.
    Keywords color ; consumer preferences ; egg shell ; oviducts ; protoporphyrin ; shell gland ; zinc
    Language English
    Dates of publication 2021-08
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 242586-5
    ISSN 1525-3171 ; 0032-5791
    ISSN (online) 1525-3171
    ISSN 0032-5791
    DOI 10.1016/j.psj.2021.101273
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Mitochondrial transcription factor A induces the declined mitochondrial biogenesis correlative with depigmentation of brown eggshell in aged laying hens.

    Lu, Ming-Yuan / Wang, Wei-Wei / Qi, Guang-Hai / Xu, Li / Wang, Jing

    Poultry science

    2020  Volume 100, Issue 3, Page(s) 100811

    Abstract: Eggshell color is an important characteristic for poultry eggs. Eggs from aged hens usually have poor shell color that is unacceptable for the table egg market. The objective of this study was to examine effects of pigment synthesis and mitochondrial ... ...

    Abstract Eggshell color is an important characteristic for poultry eggs. Eggs from aged hens usually have poor shell color that is unacceptable for the table egg market. The objective of this study was to examine effects of pigment synthesis and mitochondrial biogenesis on brown eggshell color of aged laying hens. In this trial, 8 hens laying eggs with darker shell color and 8 hens laying eggs with lighter shell color were selected from 300 62-week-old Hy-Line brown-egg laying hens. Results showed that egg weight (P < 0.05), eggshell weight (P < 0.01), protoporphyrin IX (Pp IX) content of the eggshell and the shell gland (P < 0.001), and biliverdin content of the shell gland (P < 0.001) were significantly declined in the light-shell group compared with the dark-shell group. Relative mRNA expression of δ-aminolevulinic acid synthase1 (ALAS1) (P < 0.05), coproporphyrinogen oxidase (P < 0.01), ATP-binding cassette transporter ABCG2 (P < 0.01), and mitochondrial transcription factor A (P < 0.05) was reduced in hens laying lighter brown eggshell. Moreover relative mRNA expression of mitochondrial DNA copy number (P < 0.01), mitochondrial NADH dehydrogenase subunit 4 (P < 0.05), mitochondrial ATP synthase F0 subunit 8 (P < 0.05), and mitochondrial cytochrome c oxidase 1 (P < 0.01) was significantly decreased in the shell gland of the light-shell group. In addition, NAD
    MeSH term(s) Age Factors ; Animals ; Chickens/genetics ; DNA-Binding Proteins/genetics ; Egg Shell/physiology ; Female ; Mitochondrial Proteins/genetics ; Organelle Biogenesis ; Ovum/physiology ; Pigmentation/genetics ; Transcription Factors/genetics
    Chemical Substances DNA-Binding Proteins ; Mitochondrial Proteins ; Transcription Factors ; mitochondrial transcription factor A
    Language English
    Publishing date 2020-11-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 242586-5
    ISSN 1525-3171 ; 0032-5791
    ISSN (online) 1525-3171
    ISSN 0032-5791
    DOI 10.1016/j.psj.2020.10.065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Mechanisms associated with the depigmentation of brown eggshells: a review.

    Lu, Ming-Yuan / Xu, Li / Qi, Guang-Hai / Zhang, Hai-Jun / Qiu, Kai / Wang, Jing / Wu, Shu-Geng

    Poultry science

    2021  Volume 100, Issue 8, Page(s) 101273

    Abstract: Eggshell color is an important shell quality trait that influences consumer preference. It is also of particular importance with respect to sexual signaling and the physiological and mechanical properties of shell pigment. Pigments include protoporphyrin ...

    Abstract Eggshell color is an important shell quality trait that influences consumer preference. It is also of particular importance with respect to sexual signaling and the physiological and mechanical properties of shell pigment. Pigments include protoporphyrin IX, biliverdin, and traces of biliverdin zinc chelates, with brown eggs being notably rich in protoporphyrin IX, the synthesis of which has a marked effect on the intensity of brown eggshell color. This pigment is initially synthesized in the eggshell gland within the oviduct of laying hens and is subsequently deposited throughout the cuticular and calcareous layers of brown eggshell. In this review, we describe the factors affecting brown eggshell color and potential targets for the regulation of pigment synthesis. Protoporphyrin IX synthesis might be compromised by synthetase-mediated pigment synthesis, the redox status of the female birds, and regulation of the nuclear transcription factors associated with δ-aminolevulinic acid synthetase1. We believe that this review will provide a valuable reference for those engaged in studying eggshell depigmentation.
    MeSH term(s) Animals ; Biliverdine ; Chickens ; Egg Shell ; Female ; Ovum ; Pigmentation
    Chemical Substances Biliverdine (O9MIA842K9)
    Language English
    Publishing date 2021-05-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 242586-5
    ISSN 1525-3171 ; 0032-5791
    ISSN (online) 1525-3171
    ISSN 0032-5791
    DOI 10.1016/j.psj.2021.101273
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Correlations of Molecular Weights of β-Glucans from Qingke (Tibetan Hulless Barley) to Their Multiple Bioactivities.

    Lin, Shang / Guo, Huan / Lu, Min / Lu, Ming-Yuan / Gong, Jia Duo Bu / Wang, Lu / Zhang, Qing / Qin, Wen / Wu, Ding-Tao

    Molecules (Basel, Switzerland)

    2018  Volume 23, Issue 7

    Abstract: β-glucans have been considered the major bioactive components in Qingke (Tibetan hulless barley). However, the structure⁻function relationships of β-glucans from Qingke have seldom been investigated. Whether the bioactivities of Qingke β-glucans are ... ...

    Abstract β-glucans have been considered the major bioactive components in Qingke (Tibetan hulless barley). However, the structure⁻function relationships of β-glucans from Qingke have seldom been investigated. Whether the bioactivities of Qingke β-glucans are closely correlated to their molecular weights remains unknown. Therefore, in order to explore Qingke β-glucans as functional/healthy food ingredients for industrial applications, and to better understand their structure⁻function relationships, correlations of molecular weights of Qingke β-glucans to their in vitro binding properties, inhibitory activities on digestive enzymes (α-amylase and pancreatic lipase), anti-inflammatory activities, and anticancer activities were systematically investigated. Results showed that the in vitro binding properties and the inhibitory activities on α-amylase and pancreatic lipase of Qingke β-glucans were positively correlated to their molecular weights. However, the anti-inflammatory activities of Qingke β-glucans increased as their molecular weights decreased. Furthermore, Qingke β-glucans exhibited selectively anti-cancer activities in vitro. Positive and negative correlations of molecular weights to inhibitory effects against A549 cells and MDA-MB-231 cells were observed, respectively. However, the inhibitory effects of Qingke β-glucans against HCT116 cells were not associated with their molecular weights. Results suggested that the molecular weights of Qingke β-glucans significantly affected their bioactivities, which was beneficial for a better understanding of their structure⁻function relationships. Moreover, results showed that Qingke β-glucans could be further explored as functional/healthy food ingredients for industrial applications due to their multiple health benefits.
    MeSH term(s) A549 Cells ; Enzyme Inhibitors/chemistry ; Hordeum/chemistry ; Humans ; Lipase/antagonists & inhibitors ; Lipase/chemistry ; Lipase/metabolism ; Molecular Weight ; alpha-Amylases/antagonists & inhibitors ; alpha-Amylases/chemistry ; alpha-Amylases/metabolism ; beta-Glucans/chemistry
    Chemical Substances Enzyme Inhibitors ; beta-Glucans ; Lipase (EC 3.1.1.3) ; alpha-Amylases (EC 3.2.1.1)
    Language English
    Publishing date 2018-07-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules23071710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Effects of dietary Enteromorpha powder on reproduction-related hormones and genes during the late laying period of Zi geese.

    Ma, Wei Qing / Zhao, Dan Hua / Cheng, Huang Zuo / Wang, Si Bo / Yang, Ji / Cui, Hong Xia / Lu, Ming Yuan / Wu, Hong Zhi / Xu, Li / Liu, Guo Jun

    Animal bioscience

    2020  Volume 34, Issue 3, Page(s) 457–462

    Abstract: Objective: The aim of this study was to investigate the effects of Enteromorpha powder supplementation on reproduction-related hormones and genes in the late laying period of Zi geese.: Methods: A total of 312 (1-year-old) Zi geese with similar ... ...

    Abstract Objective: The aim of this study was to investigate the effects of Enteromorpha powder supplementation on reproduction-related hormones and genes in the late laying period of Zi geese.
    Methods: A total of 312 (1-year-old) Zi geese with similar laying rate were randomly divided into 2 groups with 6 replicates each, each with 21 female geese and 5 male geese. The control group was fed with a basal diet and the test group was fed with a diet containing 3% Enteromorpha powder. The trial period lasted for 7 weeks.
    Results: Our results showed that the laying rate was improved in the test group at each week of trial (p<0.01), and the levels of estradiol in serum and prolactin in ovary were increased compared with the control group (p<0.05).
    Conclusion: Based on above results, Enteromorpha powder supplementation at 3% could promote reproductive performance during the late laying period of Zi geese.
    Language English
    Publishing date 2020-08-30
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2765-0189
    ISSN 2765-0189
    DOI 10.5713/ajas.20.0368
    Database MEDical Literature Analysis and Retrieval System OnLINE

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