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Article ; Online: A Comprehensive Overview of the Role of Visual Cortex Malfunction in Depressive Disorders: Opportunities and Challenges.

Wu, Fangfang / Lu, Qingbo / Kong, Yan / Zhang, Zhijun

2023 Volume 39, Issue 9, Page(s) 1426–1438

Abstract: Major depressive disorder (MDD) is a highly heterogeneous mental disorder, and its complex etiology and unclear mechanism are great obstacles to the diagnosis and treatment of the disease. Studies have shown that abnormal functions of the visual cortex ... ...

Abstract	Major depressive disorder (MDD) is a highly heterogeneous mental disorder, and its complex etiology and unclear mechanism are great obstacles to the diagnosis and treatment of the disease. Studies have shown that abnormal functions of the visual cortex have been reported in MDD patients, and the actions of several antidepressants coincide with improvements in the structure and synaptic functions of the visual cortex. In this review, we critically evaluate current evidence showing the involvement of the malfunctioning visual cortex in the pathophysiology and therapeutic process of depression. In addition, we discuss the molecular mechanisms of visual cortex dysfunction that may underlie the pathogenesis of MDD. Although the precise roles of visual cortex abnormalities in MDD remain uncertain, this undervalued brain region may become a novel area for the treatment of depressed patients.
MeSH term(s)	Humans ; Depressive Disorder, Major/therapy ; Depressive Disorder, Major/pathology ; Brain/pathology ; Antidepressive Agents/therapeutic use ; Visual Cortex/pathology
Chemical Substances	Antidepressive Agents
Language	English
Publishing date	2023-03-30
Publishing country	Singapore
Document type	Journal Article ; Review
ZDB-ID	2419741-5
ISSN	1995-8218 ; 1673-7067
ISSN (online)	1995-8218
ISSN	1673-7067
DOI	10.1007/s12264-023-01052-7
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Zs.A 6734: Show issues

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Article ; Online: Hydrogen sulfide in health and diseases: cross talk with noncoding RNAs.

Lu, Qing-Bo / Ding, Yi / Fu, Xiao / Sun, Hai-Jian / Zhang, Ji-Ru

American journal of physiology. Cell physiology

2023 Volume 324, Issue 4, Page(s) C856–C877

Abstract: Hydrogen sulfide ( ... ...

Abstract	Hydrogen sulfide (H
MeSH term(s)	Animals ; Humans ; Hydrogen Sulfide/metabolism ; Cystathionine ; Gasotransmitters ; Signal Transduction ; Nitric Oxide ; Cystathionine gamma-Lyase ; Mammals/metabolism
Chemical Substances	Hydrogen Sulfide (YY9FVM7NSN) ; Cystathionine (375YFJ481O) ; Gasotransmitters ; Nitric Oxide (31C4KY9ESH) ; Cystathionine gamma-Lyase (EC 4.4.1.1)
Language	English
Publishing date	2023-03-06
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	392098-7
ISSN	1522-1563 ; 0363-6143
ISSN (online)	1522-1563
ISSN	0363-6143
DOI	10.1152/ajpcell.00507.2022
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Article ; Online: Potential clinical value of fibrinogen-like protein 1 as a serum biomarker for the identification of diabetic cardiomyopathy.

Liu, Yao / Wang, Min / Su, Jia-Bao / Fu, Xiao / Zheng, Guan-Li / Guo, Shan / Zhang, Li-Juan / Lu, Qing-Bo

Scientific reports

2024 Volume 14, Issue 1, Page(s) 10311

Abstract: Diabetic individuals with diabetic cardiomyopathy (DbCM) present with abnormal myocardial structure and function. DbCM cannot be accurately diagnosed due to the lack of suitable diagnostic biomarkers. In this study, 171 eligible participants were divided ...

Abstract	Diabetic individuals with diabetic cardiomyopathy (DbCM) present with abnormal myocardial structure and function. DbCM cannot be accurately diagnosed due to the lack of suitable diagnostic biomarkers. In this study, 171 eligible participants were divided into a healthy control (HC), type 2 diabetes mellitus (T2DM) patients without DbCM (T2DM), or DbCM group. Serum fibrinogen-like protein 1 (FGL-1) and other biochemical parameters were determined for all participants. Serum FGL-1 levels were significantly higher in patients with DbCM compared with those in the T2DM group and HCs. Serum FGL-1 levels were negatively correlated with left ventricular fractional shortening and left ventricular ejection fraction (LVEF) and positively correlated with left ventricular mass index in patients with DbCM after adjusting for age, sex and body mass index. Interaction of serum FGL-1 and triglyceride levels on LVEF was noted in patients with DbCM. A composite marker including serum FGL-1 and triglycerides could differentiate patients with DbCM from those with T2DM and HCs with an area under the curve of 0.773 and 0.789, respectively. Composite marker levels were negatively correlated with N-terminal B-type natriuretic peptide levels in patients with DbCM. Circulating FGL-1 may therefore be a valuable index reflecting cardiac functions in DbCM and to diagnose DbCM.
MeSH term(s)	Humans ; Male ; Female ; Fibrinogen/metabolism ; Fibrinogen/analysis ; Diabetic Cardiomyopathies/blood ; Diabetic Cardiomyopathies/diagnosis ; Biomarkers/blood ; Middle Aged ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/complications ; Aged ; Ventricular Function, Left ; Case-Control Studies ; Stroke Volume ; Triglycerides/blood
Chemical Substances	Fibrinogen (9001-32-5) ; Biomarkers ; FGL1 protein, human ; Triglycerides
Language	English
Publishing date	2024-05-05
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-57580-3
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Article ; Online: Transcription factor cellular promoter 2 is required for upstream binding protein 1 -mediated angiogenesis.

Ren, Yanyan / YaneYang / Lu, Qingbo / Wang, Qiang / Lu, Gentao / Wei, Yanli / Zhou, Jiaqi

Gene expression patterns : GEP

2023 Volume 48, Page(s) 119308

Abstract: Objective: Angiogenesis is a key process of repairing tissue damage, and it is regulated by the delicate balance between anti-angiogenesis factors. In the present study, we investigate whether transcription factor cellular promoter 2 (TFCP2) is required ...

Abstract	Objective: Angiogenesis is a key process of repairing tissue damage, and it is regulated by the delicate balance between anti-angiogenesis factors. In the present study, we investigate whether transcription factor cellular promoter 2 (TFCP2) is required for upstream binding protein 1 (UBP1)-mediated angiogenesis. Methods: Levels of UBP1 and TFCP2 in human umbilical vein endothelial cells (HUVECs) are detected by quantitative polymerase chain reaction (q-PCR) and Western blotting (WB). Effects of UBP1 on angiogenesis and migration are detected by tube-like network formation on matrigel assay and scratch assay. The interaction between UBP1 and TFCP2 is predicted and verified by STRING and Co-immunoprecipitation (Co-IP). Results: Firstly, the UBP1 expression level was up-regulated in the stimuli of vascular endothelial growth factor (VEGF) in HUVECs, and the knockdown of UBP1 inhibited angiogenesis and migration of HUVECs. Then, UBP1 interacted with TFCP2. Besides, the TFCP2 expression level was up-regulated in VEGF-stimulated HUVECs. Furthermore, knockdown of TFCP2 inhibited angiogenesis and migration in VEGF-stimulated HUVECs, and down-regulation of UBP1 enhanced the inhibition. Conclusion: TFCP2 also plays a key role in UBP1 mediated angiogenesis of HUVECs stimulated by VEGF. These findings will provide a new theoretical basis for the treatment of angiogenic diseases.
MeSH term(s)	Humans ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism ; Transcription Factors/metabolism ; Human Umbilical Vein Endothelial Cells/metabolism ; Cell Movement ; Neovascularization, Physiologic ; Cell Proliferation ; DNA-Binding Proteins/metabolism
Chemical Substances	Vascular Endothelial Growth Factor A ; Transcription Factors ; TFCP2 protein, human ; DNA-Binding Proteins
Language	English
Publishing date	2023-03-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2058346-1
ISSN	1872-7298 ; 1567-133X
ISSN (online)	1872-7298
ISSN	1567-133X
DOI	10.1016/j.gep.2023.119308
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Zs.A 5515: Show issues

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Article: MiR-103a-3p aggravates renal cell carcinoma by targeting TMEM33.

Zhang, Jingyu / Lu, Qingbo / Pang, Haigang / Zhang, Min / Wei, Wenhai

American journal of translational research

2021 Volume 13, Issue 11, Page(s) 12694–12703

Abstract: Objective: We investigated the mechanism of miR-103a-3p-mediated renal cell carcinoma (RCC) progression.: Methods: The miR-103a-3p expressions were measured in clinical samples and in two RCC cell lines. MiR-103a-3p was inhibited or over-expressed in ...

Abstract	Objective: We investigated the mechanism of miR-103a-3p-mediated renal cell carcinoma (RCC) progression. Methods: The miR-103a-3p expressions were measured in clinical samples and in two RCC cell lines. MiR-103a-3p was inhibited or over-expressed in the 786-O and UO31 cell lines, respectively. Results: We found that miR-103a-3p is closely related to the development of RCC cells. A bioinformatics analysis and a dual-luciferase reporter gene assay revealed that there is a direct interaction between TMEM33 and miR-103a-3p. Moreover, a rescue assay further confirmed that TMEM33 overexpression can attenuate miR-103a-3p-induced RCC cell development. Conclusion: miR-103a-3p exerts a carcinogenic function in RCC by regulating TMEM33, a finding that may provide new insights into the development of prognostic markers and therapeutic targets for RCC.
Language	English
Publishing date	2021-11-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2471058-1
ISSN	1943-8141
ISSN	1943-8141
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Article ; Online: Disrupted cardiac fibroblast BCAA catabolism contributes to diabetic cardiomyopathy via a periostin/NAP1L2/SIRT3 axis.

Lu, Qing-Bo / Fu, Xiao / Liu, Yao / Wang, Zi-Chao / Liu, Shi-Yi / Li, Yu-Chao / Sun, Hai-Jian

Cellular & molecular biology letters

2023 Volume 28, Issue 1, Page(s) 93

Abstract: Background: Periostin is an extracellular matrix protein that plays a critical role in cell fate determination and tissue remodeling, but the underlying role and mechanism of periostin in diabetic cardiomyopathy (DCM) are far from clear. Thus, we aimed ... ...

Abstract	Background: Periostin is an extracellular matrix protein that plays a critical role in cell fate determination and tissue remodeling, but the underlying role and mechanism of periostin in diabetic cardiomyopathy (DCM) are far from clear. Thus, we aimed to clarify the mechanistic participation of periostin in DCM. Methods: The expression of periostin was examined in DCM patients, diabetic mice and high glucose (HG)-exposed cardiac fibroblasts (CF). Gain- and loss-of-function experiments assessed the potential role of periostin in DCM pathogenesis. RNA sequencing was used to investigate the underlying mechanisms of periostin in DCM. Results: A mouse cytokine antibody array showed that the protein expression of periostin was most significantly upregulated in diabetic mouse heart, and this increase was also observed in patients with DCM or HG-incubated CF. Periostin-deficient mice were protected from diabetes-induced cardiac dysfunction and myocardial damage, while overexpression of periostin held the opposite effects. Hyperglycemia stimulated the expression of periostin in a TGF-β/Smad-dependent manner. RNA sequencing results showed that periostin upregulated the expression of nucleosome assembly protein 1-like 2 (NAP1L2) which recruited SIRT3 to deacetylate H3K27ac on the promoters of the branched-chain amino acid (BCAA) catabolism-related enzymes BCAT2 and PP2Cm, resulting in BCAA catabolism impairment. Additionally, CF-derived periostin induced hypertrophy, oxidative injury and inflammation in primary cardiomyocytes. Finally, we identified that glucosyringic acid (GA) specifically targeted and inhibited periostin to ameliorate DCM. Conclusion: Overall, manipulating periostin expression may function as a promising strategy in the treatment of DCM.
MeSH term(s)	Humans ; Mice ; Animals ; Diabetic Cardiomyopathies/genetics ; Diabetic Cardiomyopathies/metabolism ; Sirtuin 3/metabolism ; Diabetes Mellitus, Experimental/complications ; Diabetes Mellitus, Experimental/pathology ; Myocytes, Cardiac/metabolism ; Amino Acids, Branched-Chain/metabolism ; Amino Acids, Branched-Chain/pharmacology ; Fibroblasts/metabolism
Chemical Substances	Sirtuin 3 (EC 3.5.1.-) ; Amino Acids, Branched-Chain ; SIRT3 protein, human (EC 3.5.1.-)
Language	English
Publishing date	2023-11-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2108724-6
ISSN	1689-1392 ; 1689-1392
ISSN (online)	1689-1392
ISSN	1689-1392
DOI	10.1186/s11658-023-00510-4
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Article ; Online: Chicoric acid ameliorates sepsis-induced cardiomyopathy via regulating macrophage metabolism reprogramming.

Sun, Hai-Jian / Zheng, Guan-Li / Wang, Zi-Chao / Liu, Yao / Bao, Neng / Xiao, Ping-Xi / Lu, Qing-Bo / Zhang, Ji-Ru

Phytomedicine : international journal of phytotherapy and phytopharmacology

2023 Volume 123, Page(s) 155175

Abstract: Background: Sepsis-related cardiac dysfunction is believed to be a primary cause of high morbidity and mortality. Metabolic reprogramming is closely linked to NLRP3 inflammasome activation and dysregulated glycolysis in activated macrophages, leading to ...

Abstract	Background: Sepsis-related cardiac dysfunction is believed to be a primary cause of high morbidity and mortality. Metabolic reprogramming is closely linked to NLRP3 inflammasome activation and dysregulated glycolysis in activated macrophages, leading to inflammatory responses in septic cardiomyopathy. Succinate dehydrogenase (SDH) and succinate play critical roles in the progression of metabolic reprogramming in macrophages. Inhibition of SDH may be postulated as an effective strategy to attenuate macrophage activation and sepsis-induced cardiac injury. Purpose: This investigation was designed to examine the role of potential compounds that target SDH in septic cardiomyopathy and the underlying mechanisms involved. Methods/results: From a small molecule pool containing about 179 phenolic compounds, we found that chicoric acid (CA) had the strongest ability to inhibit SDH activity in macrophages. Lipopolysaccharide (LPS) exposure stimulated SDH activity, succinate accumulation and superoxide anion production, promoted mitochondrial dysfunction, and induced the expression of hypoxia-inducible factor-1α (HIF-1α) in macrophages, while CA ameliorated these changes. CA pretreatment reduced glycolysis by elevating the NAD Conclusion: These results highlight the therapeutic role of CA in the resolution of sepsis-induced cardiac inflammation.
MeSH term(s)	Humans ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Inflammasomes/metabolism ; Tubulin/metabolism ; Metabolic Reprogramming ; Macrophages/metabolism ; Succinates/adverse effects ; Cardiomyopathies/drug therapy ; Cardiomyopathies/etiology ; Sepsis/complications ; Sepsis/drug therapy ; Succinic Acid/adverse effects ; Lipopolysaccharides/adverse effects ; Caffeic Acids
Chemical Substances	NLR Family, Pyrin Domain-Containing 3 Protein ; Inflammasomes ; chicoric acid (S4YY3V8YHD) ; Tubulin ; Succinates ; Succinic Acid (AB6MNQ6J6L) ; Lipopolysaccharides ; Caffeic Acids
Language	English
Publishing date	2023-10-31
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1205240-1
ISSN	1618-095X ; 0944-7113
ISSN (online)	1618-095X
ISSN	0944-7113
DOI	10.1016/j.phymed.2023.155175
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Zs.A 4115: Show issues

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Book ; Online: Lookup Table meets Local Laplacian Filter

Zhang, Feng / Tian, Ming / Li, Zhiqiang / Xu, Bin / Lu, Qingbo / Gao, Changxin / Sang, Nong

Pyramid Reconstruction Network for Tone Mapping

2023

Abstract: Tone mapping aims to convert high dynamic range (HDR) images to low dynamic range (LDR) representations, a critical task in the camera imaging pipeline. In recent years, 3-Dimensional LookUp Table (3D LUT) based methods have gained attention due to their ...

Abstract	Tone mapping aims to convert high dynamic range (HDR) images to low dynamic range (LDR) representations, a critical task in the camera imaging pipeline. In recent years, 3-Dimensional LookUp Table (3D LUT) based methods have gained attention due to their ability to strike a favorable balance between enhancement performance and computational efficiency. However, these methods often fail to deliver satisfactory results in local areas since the look-up table is a global operator for tone mapping, which works based on pixel values and fails to incorporate crucial local information. To this end, this paper aims to address this issue by exploring a novel strategy that integrates global and local operators by utilizing closed-form Laplacian pyramid decomposition and reconstruction. Specifically, we employ image-adaptive 3D LUTs to manipulate the tone in the low-frequency image by leveraging the specific characteristics of the frequency information. Furthermore, we utilize local Laplacian filters to refine the edge details in the high-frequency components in an adaptive manner. Local Laplacian filters are widely used to preserve edge details in photographs, but their conventional usage involves manual tuning and fixed implementation within camera imaging pipelines or photo editing tools. We propose to learn parameter value maps progressively for local Laplacian filters from annotated data using a lightweight network. Our model achieves simultaneous global tone manipulation and local edge detail preservation in an end-to-end manner. Extensive experimental results on two benchmark datasets demonstrate that the proposed method performs favorably against state-of-the-art methods. Comment: 12 pages, 6 figures, accepted by NeurlPS 2023
Keywords	Computer Science - Computer Vision and Pattern Recognition ; Electrical Engineering and Systems Science - Image and Video Processing
Subject code	006
Publishing date	2023-10-26
Publishing country	us
Document type	Book ; Online
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Article ; Online: Impact of obesity-related indicators on first-pass effect in patients with ischemic stroke receiving mechanical thrombectomy.

Zhang, Junliu / Long, Ling / Li, Jie / Zhang, Heng / Yan, Wei / Abulimiti, Adilijiang / Abulajiang, Nuerbiya / Lu, Qingbo / Nguyen, Thanh N / Cai, Xiaodong

Neuroradiology

2024

Abstract: Purpose: The first-pass effect (FPE), defined as complete revascularization after a single thrombectomy pass in large vessel occlusion, is a predictor of good prognosis in patients with acute ischemic stroke (AIS) receiving mechanical thrombectomy (MT). ...

Abstract	Purpose: The first-pass effect (FPE), defined as complete revascularization after a single thrombectomy pass in large vessel occlusion, is a predictor of good prognosis in patients with acute ischemic stroke (AIS) receiving mechanical thrombectomy (MT). We aimed to evaluate obesity-related indicators if possible be predictors of FPE. Methods: We consecutively enrolled patients with AIS who were treated with MT between January 2019 and December 2021 at our institution. Baseline characteristics, procedure-related data, and laboratory test results were retrospectively analyzed. A multivariable logistic regression analysis was performed to evaluate the independent predictors of FPE. Results: A total of 151 patients were included in this study, of whom 47 (31.1%) had FPE. After adjusting for confounding factors, the independent predictors of achieving FPE were low levels of body mass index (BMI) (OR 0.85, 95% CI 0.748 to 0.971), non-intracranial atherosclerotic stenosis (OR 4.038, 95% CI 1.46 to 11.14), and non-internal carotid artery occlusion (OR 13.14, 95% CI 2.394 to 72.11). Patients with lower total cholesterol (TC) (< 3.11 mmol/L) were more likely to develop FPE than those with higher TC (≥ 4.63 mmol/L) (OR 4.280; 95% CI 1.24 to 14.74) CONCLUSION: Lower BMI, non-intracranial atherosclerotic stenosis, non-internal carotid artery occlusion, and lower TC levels were independently associated with increased rates of FPE in patients with AIS who received MT therapy. FPE was correlated with better clinical outcomes after MT.
Language	English
Publishing date	2024-04-16
Publishing country	Germany
Document type	Journal Article
ZDB-ID	123305-1
ISSN	1432-1920 ; 0028-3940
ISSN (online)	1432-1920
ISSN	0028-3940
DOI	10.1007/s00234-024-03350-x
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Zs.A 658: Show issues

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Article ; Online: Deficiency of neutral cholesterol ester hydrolase 1 (NCEH1) impairs endothelial function in diet-induced diabetic mice.

Sun, Hai-Jian / Ni, Zhang-Rong / Liu, Yao / Fu, Xiao / Liu, Shi-Yi / Hu, Jin-Yi / Sun, Qing-Yi / Li, Yu-Chao / Hou, Xiao-Hui / Zhang, Ji-Ru / Zhu, Xue-Xue / Lu, Qing-Bo

Cardiovascular diabetology

2024 Volume 23, Issue 1, Page(s) 138

Abstract: Background: Neutral cholesterol ester hydrolase 1 (NCEH1) plays a critical role in the regulation of cholesterol ester metabolism. Deficiency of NCHE1 accelerated atherosclerotic lesion formation in mice. Nonetheless, the role of NCEH1 in endothelial ... ...

Abstract	Background: Neutral cholesterol ester hydrolase 1 (NCEH1) plays a critical role in the regulation of cholesterol ester metabolism. Deficiency of NCHE1 accelerated atherosclerotic lesion formation in mice. Nonetheless, the role of NCEH1 in endothelial dysfunction associated with diabetes has not been explored. The present study sought to investigate whether NCEH1 improved endothelial function in diabetes, and the underlying mechanisms were explored. Methods: The expression and activity of NCEH1 were determined in obese mice with high-fat diet (HFD) feeding, high glucose (HG)-induced mouse aortae or primary endothelial cells (ECs). Endothelium-dependent relaxation (EDR) in aortae response to acetylcholine (Ach) was measured. Results: Results showed that the expression and activity of NCEH1 were lower in HFD-induced mouse aortae, HG-exposed mouse aortae ex vivo, and HG-incubated primary ECs. HG exposure reduced EDR in mouse aortae, which was exaggerated by endothelial-specific deficiency of NCEH1, whereas NCEH1 overexpression restored the impaired EDR. Similar results were observed in HFD mice. Mechanically, NCEH1 ameliorated the disrupted EDR by dissociating endothelial nitric oxide synthase (eNOS) from caveolin-1 (Cav-1), leading to eNOS activation and nitric oxide (NO) release. Moreover, interaction of NCEH1 with the E3 ubiquitin-protein ligase ZNRF1 led to the degradation of Cav-1 through the ubiquitination pathway. Silencing Cav-1 and upregulating ZNRF1 were sufficient to improve EDR of diabetic aortas, while overexpression of Cav-1 and downregulation of ZNRF1 abolished the effects of NCEH1 on endothelial function in diabetes. Thus, NCEH1 preserves endothelial function through increasing NO bioavailability secondary to the disruption of the Cav-1/eNOS complex in the endothelium of diabetic mice, depending on ZNRF1-induced ubiquitination of Cav-1. Conclusions: NCEH1 may be a promising candidate for the prevention and treatment of vascular complications of diabetes.
MeSH term(s)	Animals ; Male ; Mice ; Aorta/enzymology ; Aorta/physiopathology ; Aorta/metabolism ; Aorta/drug effects ; Aorta/pathology ; Caveolin 1/metabolism ; Caveolin 1/deficiency ; Caveolin 1/genetics ; Cells, Cultured ; Diabetes Mellitus, Experimental/enzymology ; Diabetes Mellitus, Experimental/physiopathology ; Diet, High-Fat ; Endothelial Cells/enzymology ; Endothelial Cells/metabolism ; Endothelial Cells/drug effects ; Endothelium, Vascular/physiopathology ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/enzymology ; Endothelium, Vascular/drug effects ; Mice, Inbred C57BL ; Mice, Knockout ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type III/metabolism ; Obesity/enzymology ; Obesity/physiopathology ; Obesity/metabolism ; Signal Transduction ; Sterol Esterase/metabolism ; Sterol Esterase/genetics ; Ubiquitination ; Vasodilation/drug effects
Chemical Substances	Cav1 protein, mouse ; Caveolin 1 ; Nitric Oxide (31C4KY9ESH) ; Nitric Oxide Synthase Type III (EC 1.14.13.39) ; Nos3 protein, mouse (EC 1.14.13.39) ; Sterol Esterase (EC 3.1.1.13) ; Nceh1 protein, mouse (EC 3.1.1.-)
Language	English
Publishing date	2024-04-25
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2093769-6
ISSN	1475-2840 ; 1475-2840
ISSN (online)	1475-2840
ISSN	1475-2840
DOI	10.1186/s12933-024-02239-6
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