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Article ; Online: Editorial for "Two-Compartment Perfusion MR IVIM Model to Investigate Normal and Pathological Placental Tissue".

Lu, Tao / Wang, Yi Xiang J

Journal of magnetic resonance imaging : JMRI

2023 Volume 59, Issue 3, Page(s) 892–893

MeSH term(s)	Pregnancy ; Humans ; Female ; Placenta ; Magnetic Resonance Imaging ; Diffusion Magnetic Resonance Imaging ; Perfusion ; Motion
Language	English
Publishing date	2023-06-16
Publishing country	United States
Document type	Editorial
ZDB-ID	1146614-5
ISSN	1522-2586 ; 1053-1807
ISSN (online)	1522-2586
ISSN	1053-1807
DOI	10.1002/jmri.28860
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Article: A Case of Pseudoelevation of Serum CA19-9 Level.

Li, Gangfeng / Lu, Tao / Lv, Shanmei

Clinical laboratory

2024 Volume 70, Issue 1

Abstract: Background: Carbohydrate antigen 19-9 (CA19-9) is usually synthesized by pancreatic and bile duct cells and is present in small amounts in serum. During the period of tumor disease, its serum level significantly increases, and it is the most widely used ...

Abstract	Background: Carbohydrate antigen 19-9 (CA19-9) is usually synthesized by pancreatic and bile duct cells and is present in small amounts in serum. During the period of tumor disease, its serum level significantly increases, and it is the most widely used serum tumor marker for diagnosis and monitoring therapy of pancreatic cancer. Methods: We reported a case of abnormal elevation of serum CA19-9. Considering the possibility of detection interference, we used heterophilic antibody blocking analysis, detection by different analysis systems, and polyethylene glycol (PEG) precipitation to evaluate the reliability of abnormally elevated CA19-9 concentration. Results: Repeated measurements on the Roche Cobas 8000 system of another hospital significantly reduced the CA19-9 concentration, as did PEG precipitation. Therefore, the abnormally elevated level of CA19-9 in this patient is considered to be pseudoelevation caused by interferences. Conclusions: We suggest considering the presence of detection interference in cases with elevated CA19-9 levels but no related clinical manifestations to prevent false positives. PEG precipitation may be a simple and feasible solution to eliminate interference.
MeSH term(s)	Humans ; CA-19-9 Antigen ; Reproducibility of Results ; Biomarkers, Tumor ; Pancreatic Neoplasms/diagnosis
Chemical Substances	CA-19-9 Antigen ; Biomarkers, Tumor
Language	English
Publishing date	2024-01-12
Publishing country	Germany
Document type	Case Reports
ZDB-ID	1307629-2
ISSN	1433-6510 ; 0941-2131
ISSN	1433-6510 ; 0941-2131
DOI	10.7754/Clin.Lab.2023.230723
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Article ; Online: ADHD and family life: A cross-sectional study of ADHD prevalence among pupils in China and factors associated with parental depression.

Lu, Tao / Li, Longlong / Tang, Ying / Leavey, Gerard

PloS one

2024 Volume 19, Issue 3, Page(s) e0281226

Abstract: Background: Attention Deficit Hyperactivity Disorder (ADHD) is increasingly recognized as a major problem for children and their families in China. However, its influence on parental mental health has been seldom explored.: Objective: To examine the ... ...

Abstract	Background: Attention Deficit Hyperactivity Disorder (ADHD) is increasingly recognized as a major problem for children and their families in China. However, its influence on parental mental health has been seldom explored. Objective: To examine the prevalence of attention deficit hyperactivity disorder in a community sample of children aged 6-13 years, and the extent to which it impacts parental mental health. Method: Cross-sectional study of primary school pupils (number = 2497) in Deyang, Sichuan Province, South-West China. We used standardized instruments to identify children with ADHD symptoms and parent depression. Results: The prevalence of ADHD was 9.8%. Factors associated with the likelihood of ADHD, included family environment(P = 0.003), time spent with children(P = 0.01), parenting style(P = 0.01), and parental relationship, pupils self-harm and lower academic ability (P = 0.001). After controlling for other factors, having a child with ADHD increased the likelihood of parents' depression (OR = 4.35, CI = 2.68~7.07), additional factors included parent relationship. Conclusions: ADHD may be a common disorder among Chinese children, the symptoms of which may increase the likelihood of parent depression. There is a need for greater detection of ADHD in schools, acknowledgement of the challenges the disorder creates for academic success and family wellbeing, and psychoeducational tools for supporting parents of children with ADHD.
MeSH term(s)	Child ; Humans ; Attention Deficit Disorder with Hyperactivity/psychology ; Cross-Sectional Studies ; Depression/epidemiology ; Prevalence ; Parents/psychology ; Parenting/psychology
Language	English
Publishing date	2024-03-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0281226
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Book ; Online: A Survey on RISC-V Security

Lu, Tao

Hardware and Architecture

2021

Abstract: The Internet of Things (IoT) is an ongoing technological revolution. Embedded processors are the processing engines of smart IoT devices. For decades, these processors were mainly based on the Arm instruction set architecture (ISA). In recent years, the ... ...

Abstract	The Internet of Things (IoT) is an ongoing technological revolution. Embedded processors are the processing engines of smart IoT devices. For decades, these processors were mainly based on the Arm instruction set architecture (ISA). In recent years, the free and open RISC-V ISA standard has attracted the attention of industry and academia and is becoming the mainstream. Data security and user privacy protection are common challenges faced by all IoT devices. In order to deal with foreseeable security threats, the RISC-V community is studying security solutions aimed at achieving a root of trust (RoT) and ensuring that sensitive information on RISC-V devices is not tampered with or leaked. Many RISC-V security research projects are underway, but the academic community has not yet conducted a comprehensive survey of RISC-V security solutions. In order to fill this research gap, this paper presents an in-depth survey on RISC-V security technologies. This paper summarizes the representative security mechanisms of RISC-V hardware and architecture. Based on our survey, we predict the future research and development directions of RISC-V security. We hope that our research can inspire RISC-V researchers and developers. Comment: 39 pages, 12 figures
Keywords	Computer Science - Cryptography and Security ; Computer Science - Hardware Architecture
Subject code	303
Publishing date	2021-07-08
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Availability, price, and affordability of anti-hepatitis B virus drugs: a cross-sectional study in China.

Li, Yue / Zhang, Mengdie / Xu, Yi / Li, Xin / Lu, Tao

International journal of clinical pharmacy

2024

Abstract: Background: The global prevalence of hepatitis B virus (HBV) has presented a persistent challenge for public health prevention and treatment. However, studies that assess the public's access to anti-HBV drugs are absent.: Aim: To examine the ... ...

Abstract	Background: The global prevalence of hepatitis B virus (HBV) has presented a persistent challenge for public health prevention and treatment. However, studies that assess the public's access to anti-HBV drugs are absent. Aim: To examine the availability, pricing, and affordability of anti-HBV drugs in Jiangsu province, China and provide recommendations for improvement. Method: An enhanced methodology developed by the World Health Organization (WHO) and Health Action International was applied in a cross-sectional study that included 1026 healthcare facilities distributed in 13 prefectural-level cities in Jiangsu province. Results: Since almost all drugs had an availability of less than 30%, the accessibility of anti-HBV drugs was notably low. Primary healthcare facilities had the lowest availability, reporting 1.4% for Original Brands (OBs) and 1.7% for lowest-priced generics (LPGs). Furthermore, the northern Jiangsu region recorded the lowest availability at 0.7%. LPGs demonstrated higher availability than OBs, with median availability probabilities of 2.6% and 1.4%, respectively. The drugs listed on the WHO Essential Medicines List exhibited higher availability than those on other lists. The median price ratios for OBs, LPGs, and volume-based purchasing drugs were 0.83, 0.50, and 0.27, respectively, less than 1.5 times the international reference price. Despite favorable pricing, affordability rate was 23% for urban residents and 0% for rural residents, which was discouraging. Conclusion: Low availability and affordability of anti-HBV drugs were observed. Policy recommendations should emphasize the improvement of LPG availability by incentivizing priority prescribing. Healthcare subsidies should be provided more effectively and equitably.
Language	English
Publishing date	2024-03-12
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2601204-2
ISSN	2210-7711 ; 2210-7703 ; 0928-1231
ISSN (online)	2210-7711
ISSN	2210-7703 ; 0928-1231
DOI	10.1007/s11096-024-01706-0
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Article ; Online: Learning Optical Flow and Scene Flow With Bidirectional Camera-LiDAR Fusion.

Liu, Haisong / Lu, Tao / Xu, Yihui / Liu, Jia / Wang, Limin

IEEE transactions on pattern analysis and machine intelligence

2024 Volume 46, Issue 4, Page(s) 2378–2395

Abstract: In this paper, we study the problem of jointly estimating the optical flow and scene flow from synchronized 2D and 3D data. Previous methods either employ a complex pipeline that splits the joint task into independent stages, or fuse 2D and 3D ... ...

Abstract	In this paper, we study the problem of jointly estimating the optical flow and scene flow from synchronized 2D and 3D data. Previous methods either employ a complex pipeline that splits the joint task into independent stages, or fuse 2D and 3D information in an "early-fusion" or "late-fusion" manner. Such one-size-fits-all approaches suffer from a dilemma of failing to fully utilize the characteristic of each modality or to maximize the inter-modality complementarity. To address the problem, we propose a novel end-to-end framework, which consists of 2D and 3D branches with multiple bidirectional fusion connections between them in specific layers. Different from previous work, we apply a point-based 3D branch to extract the LiDAR features, as it preserves the geometric structure of point clouds. To fuse dense image features and sparse point features, we propose a learnable operator named bidirectional camera-LiDAR fusion module (Bi-CLFM). We instantiate two types of the bidirectional fusion pipeline, one based on the pyramidal coarse-to-fine architecture (dubbed CamLiPWC), and the other one based on the recurrent all-pairs field transforms (dubbed CamLiRAFT). On FlyingThings3D, both CamLiPWC and CamLiRAFT surpass all existing methods and achieve up to a 47.9% reduction in 3D end-point-error from the best published result. Our best-performing model, CamLiRAFT, achieves an error of 4.26% on the KITTI Scene Flow benchmark, ranking 1st among all submissions with much fewer parameters. Besides, our methods have strong generalization performance and the ability to handle non-rigid motion.
Language	English
Publishing date	2024-03-06
Publishing country	United States
Document type	Journal Article
ISSN	1939-3539
ISSN (online)	1939-3539
DOI	10.1109/TPAMI.2023.3330866
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Article: A reversible photoelectrochemical microsensor for dynamically monitoring sulfur dioxide in the epileptic brain.

Lin, Danying / Lu, Tao / Wang, Xiao / Ye, Xiaoxue / Liu, Zhihong

Chemical science

2024 Volume 15, Issue 13, Page(s) 4824–4832

Abstract: Epilepsy is considered one of the most prevalent neurological disorders, yet the precise mechanisms underlying its pathogenesis remain inadequately elucidated. Emerging evidence implicates endogenous sulfur dioxide ( ... ...

Abstract	Epilepsy is considered one of the most prevalent neurological disorders, yet the precise mechanisms underlying its pathogenesis remain inadequately elucidated. Emerging evidence implicates endogenous sulfur dioxide (SO
Language	English
Publishing date	2024-02-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2559110-1
ISSN	2041-6539 ; 2041-6520
ISSN (online)	2041-6539
ISSN	2041-6520
DOI	10.1039/d3sc06816a
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Article ; Online: Dual-signal amplified electrochemical aptasensor based on Au/MrGO and DNA nanospheres for ultra-sensitive detection of BPA without directly modified working electrode.

Hu, Liuyin / Cui, Jiahua / Lu, Tao / Wang, Yalin / Jia, Jinping

Chemosphere

2024 , Page(s) 142063

Abstract: Rapid and sensitive analysis of bisphenol A (BPA) is essential for preventing health risks to humans and animals. Hence, a signal-amplified electrochemical aptasensor without repetitive polishing and modification of working electrode was developed for ... ...

Abstract	Rapid and sensitive analysis of bisphenol A (BPA) is essential for preventing health risks to humans and animals. Hence, a signal-amplified electrochemical aptasensor without repetitive polishing and modification of working electrode was developed for BPA using Au-decorated magnetic reduced graphene oxide (Au/MrGO)-based recognition probe (RP) and DNA nanospheres (DNS)-based signal probe (SP) cooperative signal amplification. The DNS served as a signal molecule carrier and signal amplifier, while Au/MrGO acted as a signal amplifier and excellent medium for magnetic adsorption and separation. Moreover, utilizing the excellent magnetic properties of Au/MrGO eliminates the need for repetitive polishing and multi-step direct modification of the working electrode while ensuring that all detection processes take place in solution and that used Au/MrGO can be easily recycled. The proposed aptasensor exhibited not only good stability and selectivity, but also excellent sensitivity with a limit of detection (LOD) of 8.13 fg/mL (S/N=3). The aptasensor's practicality was proven by spiking recovery tests on actual water samples and comparing the results with those detected by HPLC. The excellent sensitivity and selectivity make this aptasensor an alternative and promising avenue for rapid detection of BPA in environmental monitoring.
Language	English
Publishing date	2024-04-15
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2024.142063
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Article: Relative Contributions of Climate Change and Human Activities on Vegetation Productivity Variation in National Nature Reserves on the Qinghai–Tibetan Plateau

Zhou, Jia / Lu, Tao

Remote Sensing. 2022 Sept. 16, v. 14, no. 18

2022

Abstract: National nature reserves (NNRs) are at the forefront of conservation efforts on the Qinghai–Tibetan Plateau (QTP). However, few studies have examined the vegetation dynamics and their driving forces at the whole QTP scale. In this study, we used ... ...

Abstract	National nature reserves (NNRs) are at the forefront of conservation efforts on the Qinghai–Tibetan Plateau (QTP). However, few studies have examined the vegetation dynamics and their driving forces at the whole QTP scale. In this study, we used potential Net Primary Productivity (PNPP), actual NPP (ANPP), and human-activity-induced NPP (HNPP) to analyze the vegetation dynamics of 42 NNRs on the QTP. Further, we determined the driving factors of vegetation dynamics from 2000 to 2020. The results indicate that, during the 21 years studied, ANPP increased at 83.4% of the NNRs area on the QTP. Additionally, the contributions of climate change and anthropogenic factors to ANPP variation were 59.53% and 40.47%, respectively. The contribution of temperature to ANPP variation was considered high and stable, whereas the contribution of precipitation was relatively lower and variable. Residual analysis showed that human activities had both positive (51.30%) and negative effects (48.70%) on ANPP. Using Hurst exponent analysis, we found that 31.60% of the vegetation for the NNRs on the QTP will likely remain a persistent trend, and 65.4% will be stochastic in the future. By contrast, 3.00% of the vegetation mainly located in southern QTP would show a reverse trend, with most of them distributing in southern QTP, which deserves more attention. This study may help policymakers understand the relative impacts of climate change and human activities on vegetation in the different nature reserves on the QTP.
Keywords	climate change ; humans ; net primary productivity ; temperature ; vegetation ; China
Language	English
Dates of publication	2022-0916
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2513863-7
ISSN	2072-4292
ISSN	2072-4292
DOI	10.3390/rs14184626
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Conformations and non-covalent interactions of cyclohexyl isothiocyanate and its water complex.

Xu, Yugao / Yang, Tingting / Lu, Tao / Feng, Gang

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

2023 Volume 295, Page(s) 122596

Abstract: The conformational equilibria of cyclohexyl isothiocyanate and its complex with water were studied by microwave spectroscopy combined with theoretical calculations. For the bare cyclohexyl isothiocyanate, the rotational spectra of the two conformers, ... ...

Abstract	The conformational equilibria of cyclohexyl isothiocyanate and its complex with water were studied by microwave spectroscopy combined with theoretical calculations. For the bare cyclohexyl isothiocyanate, the rotational spectra of the two conformers, namely a-trans and e-trans, were measured and analyzed. Additional mono-substituted isotopologues of two
Language	English
Publishing date	2023-03-14
Publishing country	England
Document type	Journal Article
ZDB-ID	210413-1
ISSN	1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
ISSN (online)	1873-3557
ISSN	0370-8322 ; 0584-8539 ; 1386-1425
DOI	10.1016/j.saa.2023.122596
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