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  1. Article: [Tamping foundation quality and seizing development opportunities: experience in the standardized, institutionalized and procedural construction of critical care medicine in Xinyang Central Hospital].

    Lu, Yibin

    Zhonghua wei zhong bing ji jiu yi xue

    2019  Volume 31, Issue 3, Page(s) 266–268

    Abstract: Objective: Critical care medicine is a relatively young, fast-growing discipline, but it also bears the burden of heavy life. In the past 10 years, critical care medicine has made rapid progress. It has been growing to be mature and complete, its ... ...

    Abstract Objective: Critical care medicine is a relatively young, fast-growing discipline, but it also bears the burden of heavy life. In the past 10 years, critical care medicine has made rapid progress. It has been growing to be mature and complete, its environment and equipment have been improved, and the technical ability has been continuously upgraded. However, the rapid improvement and the diversification of management modes have also brought about some concerns about medical quality. Xinyang Central Hospital is a large prefecture-grade tertiary-class A general hospital in Henan Province. As the director of the department of critical care medicine and the discipline leader of critical care medicine in Xinyang City, the author shared his opinion about how to establish a "standardized, institutionalized and procedural" management model from the perspective of department management in order to ensure medical quality and safety. We should "start from the quality control of critical care medicine, implement the concept of critical care through ward rounds, supervise the quality from the self-examination and self-correction of adverse events", in order to establish a management system for critical care patients and lay a foundation for improving medical quality and sustainable developing of critical care medicine.
    MeSH term(s) China ; Critical Care/organization & administration ; Critical Care/standards ; Hospitals, General ; Humans ; Quality of Health Care ; Tertiary Care Centers
    Language Chinese
    Publishing date 2019-03-27
    Publishing country China
    Document type Journal Article
    ISSN 2095-4352
    ISSN 2095-4352
    DOI 10.3760/cma.j.issn.2095-4352.2019.03.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Research on Influencing Factors of Innovation Network Performance of Industrial Enterprises above Designated Size in Nanjing Based on System Dynamics

    Lu Yibin / Fang Yexiang

    Complex System Modeling and Simulation, Vol 1, Iss 1, Pp 65-

    2021  Volume 76

    Abstract: Based on the method of system dynamics, this paper simulates the cycle of collaborative innovation network, involving enterprises, government, research institutions, and science and technology intermediaries from the perspective of capital flow. The ... ...

    Abstract Based on the method of system dynamics, this paper simulates the cycle of collaborative innovation network, involving enterprises, government, research institutions, and science and technology intermediaries from the perspective of capital flow. The results of model analysis show that among the influencing factors, the number of innovation achievements is the most complex variable, and the influence of patent elimination rate is the most significant. The number of Research and Development (R&D) projects is most sensitive to the positive impact of the number of technology intermediaries, and with the passage of time, this kind of effect gradually increases. At the same time, the total industrial assets are positively affected by the intensity of enterprise innovation investment, but there is about three years delay in this effect.
    Keywords innovation network ; collaborative innovation ; innovation performance ; system dynamics ; Electronic computers. Computer science ; QA75.5-76.95 ; Systems engineering ; TA168
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Tsinghua University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Numerical computation of preimage domains for spiral slit regions and simulation of flow around bodies.

    Wu, Kang / Lu, Yibin

    Mathematical biosciences and engineering : MBE

    2022  Volume 20, Issue 1, Page(s) 720–736

    Abstract: In this paper, we propose the iterative numerical methods to calculate the conformal preimage domains for the specified logarithmic spiral slit regions and develop the applications of conformal mappings in the simulations of the flow around bodies. ... ...

    Abstract In this paper, we propose the iterative numerical methods to calculate the conformal preimage domains for the specified logarithmic spiral slit regions and develop the applications of conformal mappings in the simulations of the flow around bodies. Firstly, we postulate that the boundaries of the preimage domains mapped onto logarithmic spiral slits are ellipses. The lengths of the long axes of ellipses and the coordinates of the centers are calculated using our iterative methods. Secondly, each type of the presented iterative method calculates numerical conformal mappings via solving the boundary integral equation with the generalized Neumann kernel. Finally, numerical examples show the convergence and availability of our iterative methods and display the simulations of the flow around the bodies as an application.
    MeSH term(s) Computer Simulation
    Language English
    Publishing date 2022-10-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2265126-3
    ISSN 1551-0018 ; 1551-0018
    ISSN (online) 1551-0018
    ISSN 1551-0018
    DOI 10.3934/mbe.2023033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Interaction between rs10052957 polymorphism of glucocorticoid receptor gene and environmental factors increases the risk of suicide

    ZHOU Yanhua1 / LU Yibin / QU Ming / HUANG Binhui / ZHANG Linna

    陆军军医大学学报, Vol 45, Iss 12, Pp 1354-

    a study of 66 cases

    2023  Volume 1362

    Abstract: Objective To investigate the interactions of the polymorphisms of hypothalamic-pituitary-adrenal (HPA) axis related genes, corticotropin-releasing hormone receptor Ⅱ (CRHR2), FK506 binding protein 5 (FKBP5), and glucocorticoid receptor (NR3C1) with ... ...

    Abstract Objective To investigate the interactions of the polymorphisms of hypothalamic-pituitary-adrenal (HPA) axis related genes, corticotropin-releasing hormone receptor Ⅱ (CRHR2), FK506 binding protein 5 (FKBP5), and glucocorticoid receptor (NR3C1) with environmental factors, and their association with suicide attempts. Methods A total of 66 depressed patients (32.2±16.7 years old, 30 males and 36 females, case group) who seek medical advice due to attempted suicide were recruited from the psychiatry departments of the Affiliated Hospital of Guangdong Medical University, Dongguan Seventh People's Hospital and Kuitun Hospital of Ili Kazakh Autonomous Prefecture during March 2017 to September 2018. Forty-nine unrelated healthy individuals (32.7±11.0 years old, 23 males and 26 females, control group) were selected from the Health Screening Centre of the Affiliated Hospital of Guangdong Medical University during the same period. Snapshot genotyping was used to test the single nucleotide polymorphism (SNP) loci of the target genes. Life event scale (LES) was used to assess life stress of individuals over the past year. Trier social stress test (TSST) was employed to evaluate HPA axis reactivity. Mmultifactor dimensionality reduction (MDR) analysis was adopted to analyze the interactions among genes, life events and HPA axis reactivity. Results The total LES score was significantly higher (30.47±27.22 vs 7.80±10.14, P < 0.001), but the HPA axis reactivity was obviously lower in the case group than the control group (P < 0.001). There were no statistical differences in genotype frequencies and allele frequencies between the 2 groups at 5 SNPs (NR3C1: rs9324924 and rs10052957; FKBP5: rs3800373 and rs9296158; CRHR2: rs3779250). MDR analysis indicated that the best interaction model was the third-order model constructed by NR3C1 rs10052957 polymorphism, life events and HPA axis reactivity, with the highest accuracy of 0.883 7 for sample test (P=0.009 8). Conclusion The interaction of NR3C1 rs10052957 polymorphism, HPA ...
    Keywords suicide attempt ; hypothalamic-pituitary-adrenal axis related genes ; hpa axis reactivity ; life event ; Medicine (General) ; R5-920
    Subject code 616
    Language Chinese
    Publishing date 2023-06-01T00:00:00Z
    Publisher Editorial Office of Journal of Army Medical University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Atomization Characteristics of Hydrogen Peroxide Solutions in Electrostatic Field.

    Huang, Xuefeng / Sheng, Ling / Lu, Yibin / Li, Shengji

    Micromachines

    2022  Volume 13, Issue 5

    Abstract: Hydrogen peroxide ( ... ...

    Abstract Hydrogen peroxide (H
    Language English
    Publishing date 2022-05-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi13050771
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Analysis and Processing of Flow Alarm about Fresenius 4008 S Hemodialysis Machine].

    Yang, Fei / Lu, Yibin

    Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation

    2020  Volume 44, Issue 3, Page(s) 280–282

    Abstract: The Fresenius 4008 S hemodialysis machine is one of the main hemodialysis machines in our hospital. Because of its longer service life, the probability of malfunction is larger. For flow alarm is the typical fault of this model, we combined with ... ...

    Abstract The Fresenius 4008 S hemodialysis machine is one of the main hemodialysis machines in our hospital. Because of its longer service life, the probability of malfunction is larger. For flow alarm is the typical fault of this model, we combined with practical maintenance experience and theoretical technology, then briefly analyzed and summarized the malfunction. On the principle of easy to difficult, we check in order from five aspects, they are pipeline blockage, aging of the degassing pump or flow pump, the float switch malfunction, valve abnormality and the control circuit problem. Through this one-by-one and systematic troubleshooting, the flow alarm can usually be solved, also we can save the maintenance time and the cost.
    MeSH term(s) Maintenance ; Renal Dialysis
    Language Chinese
    Publishing date 2020-07-04
    Publishing country China
    Document type Journal Article
    ISSN 1671-7104
    ISSN 1671-7104
    DOI 10.3969/j.issn.1671-7104.2020.03.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: MiR-92a targets PTEN/PI3K/Akt pathway to inhibit autophagy in non-small cell lung cancer cells

    HU Aini / WANG Yuping / LU Yibin

    Di-san junyi daxue xuebao, Vol 42, Iss 13, Pp 1301-

    2020  Volume 1307

    Abstract: Objective To investigate the effect of miR-92a on autophagy in non-small cell lung cancer cells (NSCLC) and its possible mechanism. Methods The paired NSCLC tissues and paracancerous tissues were collected from 53 NSCLC patients treated in the Second ... ...

    Abstract Objective To investigate the effect of miR-92a on autophagy in non-small cell lung cancer cells (NSCLC) and its possible mechanism. Methods The paired NSCLC tissues and paracancerous tissues were collected from 53 NSCLC patients treated in the Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine from January 2016 to December 2018. The expression levels of miR-92a and PTEN, p-PI3K, p-Akt and LC3-Ⅱ in the paired tissues were detected by RT-PCR and immunohistochemical assay. MiR-92a-mimics, miR-92a-NC and miR-92a-inhibitor were respectively transfected into A549 cells. After 48 h, acridine orange staining was used to detect autophagy. Dual luciferase reporter assay was employed to verify the targeting relationship between miR-92a and PTEN, and Western blotting was performed to detect the expression of PTEN, p-PI3K, p-Akt and LC3-Ⅱ in each transfected cells. Results The mRNA expression of miR-92a was significantly higher in the NSCLC tissues than the normal lung tissues (P < 0.001). The percentages of p-PI3K and p-Akt positive cells were obviously higher, while those of LC3-Ⅱ and PTEN positive cells were notably lower in the cancer tissues than the normal lung tissues (P < 0.001). There were no statistical differences in the expression levels of miR-92a, PTEN and LC3-Ⅱ among the patients of different genders and ages (P>0.05). However, for the patients with lymph node metastasis, at TNM Ⅲ~Ⅳ stage and lower differentiation, the expression levels of miR-92a in the cancer tissue was significantly higher when compared with those without metastasis, at TNM Ⅰ~Ⅱ stage and higher differentiation (P < 0.01). While opposite phenomena were observe when concerning of the expression of PTEN and LC3-Ⅱ (P < 0.01). Pyridine orange staining showed that the intracellular fluorescence was the weakest in the A549 cells transfected with miR-92a-mimics, while strongest in those with miR-92a-inhibitor. Among the 3 groups of cells with transfection, the expression of p-Akt and p-PI3K protein was ...
    Keywords non-small cell lung cancer ; mir-92a ; pten ; pi3k/akt signaling pathway ; autophagy ; Medicine (General) ; R5-920
    Subject code 616
    Language Chinese
    Publishing date 2020-07-01T00:00:00Z
    Publisher Editorial Office of Journal of Third Military Medical University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Reducing the contaminant dispersion and infection risks in the train cabins by adjusting the inlet turbulence intensity: A study based on turbulence simulation.

    Wang, Tiantian / Zheng, Yaxin / Lu, Yibin / Shi, Fangcheng / Ji, Peng / Qian, Bosen / Zhang, Lei / Liu, Dongrun / Wang, Jiabin / Yang, Buyao

    The Science of the total environment

    2024  Volume 930, Page(s) 172735

    Abstract: Existing studies on ventilation in closed spaces mainly considered the average inlet velocity and ignored the influence of inlet turbulent fluctuation. However, the variation in inlet turbulence intensity (TI) is considerable and significantly affects ... ...

    Abstract Existing studies on ventilation in closed spaces mainly considered the average inlet velocity and ignored the influence of inlet turbulent fluctuation. However, the variation in inlet turbulence intensity (TI) is considerable and significantly affects the dispersion of contaminants. This study conducts numerical simulations verified by experiments to investigate the effect of the inlet TI on train contaminants dispersion and analyze infection probability variation. Firstly, the unsteady Reynolds-averaged Navier-Stokes (URANS) method and improved delayed detached eddy simulation (IDDES) method are compared in simulating the internal airflow characteristics based on the on-site measurement. The results indicate that the latter dominates in capturing airflow pulsations more than the former, although the mean airflow results obtained from both methods agree well with experimental results. Furthermore, the IDDES method is employed to investigate the effect of the inlet TI on contaminant dispersion, and the infection risks are also assessed using the improved probability model. The results show that, with the increase of TI from 5 % to 30 %, the contaminant removal grows considerably, with the removal index rising from 0.23 to 1.86. The increased TI leads to the overall and local infection risks of occupants descending significantly, wherein the former decreases from 1.53 % to 0.88 % with a reduction rate of 42 %, and the latter drops from 3.30 % to 2.16 % with a mitigation rate of 35 %. The findings can serve as solid guidelines for numerical method selection in accurately capturing the indoor dynamic airflow distribution and for the ventilation parameters design regarding TI inside trains to mitigate the airborne infection risk.
    Language English
    Publishing date 2024-04-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.172735
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Peripheral perfusion index predicting prolonged ICU stay earlier and better than lactate in surgical patients: an observational study.

    Shi, Xinge / Xu, Ming / Yu, Xu / Lu, Yibin

    BMC anesthesiology

    2020  Volume 20, Issue 1, Page(s) 153

    Abstract: Background: Peripheral perfusion index (PPI) is an indicator reflecting perfusion. Patients undergoing long time surgeries are more prone to hypoperfusion and increased lactate. Few studies focusing on investigating the association between PPI and ... ...

    Abstract Background: Peripheral perfusion index (PPI) is an indicator reflecting perfusion. Patients undergoing long time surgeries are more prone to hypoperfusion and increased lactate. Few studies focusing on investigating the association between PPI and surgical patients' prognoses. We performed this study to find it out.
    Methods: From January 2019 to September 2019, we retrospected all surgical patients who were transferred to ICU, Xinyang Central hospital, Henan province, China. Inclusive criteria: age ≥ 18 years old; surgical length ≥ 120 min. Exclusive criteria: died in ICU; discharging against medical advice; existing diseases affecting blood flow of upper limbs, for example, vascular thrombus in arms; severe liver dysfunction. We defined "prolonged ICU stay" as patients with their length of ICU stay longer than 48 h. According to the definition, patients were divided into two groups: "prolonged group" (PG) and "non-prolong group" (nPG). Baseline characteristics, surgical and therapeutic information, ICU LOS, SOFA and APACHE II were collected. Besides we gathered data of following parameters at 3 time points (T0: ICU admission; T1: 6 h after admission; T2: 12 h after admission): mean artery pressure (MAP), lactate, heart rate (HR), PPI and body temperature. Data were compared between the 2 groups. Multivariable binary logistic regression and ROC (receiver operating characteristic) curves were performed to find the association between perfusion indictors and ICU LOS.
    Results: Eventually, 168 patients were included, 65 in PG and 103 in nPG. Compared to nPG, patients in PG had higher blood lactate and lower PPI. PPI showed significant difference between two groups earlier than lactate (T
    Conclusions: PPI and blood lactate at T
    MeSH term(s) Adult ; Aged ; Female ; Hemodynamics ; Humans ; Intensive Care Units ; Lactic Acid/blood ; Length of Stay ; Male ; Middle Aged ; Perfusion Index ; Retrospective Studies
    Chemical Substances Lactic Acid (33X04XA5AT)
    Language English
    Publishing date 2020-06-18
    Publishing country England
    Document type Journal Article ; Observational Study
    ISSN 1471-2253
    ISSN (online) 1471-2253
    DOI 10.1186/s12871-020-01072-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Nursing of Patients Critically Ill With Coronavirus Disease Treated With Extracorporeal Membrane Oxygenation.

    Tu, Zhongyu / Xia, Qingbin / Xu, Ming / Lu, Yibin

    Journal of emergency nursing

    2020  Volume 46, Issue 6, Page(s) 862–868.e2

    MeSH term(s) COVID-19/nursing ; COVID-19/therapy ; Critical Illness ; Emergency Nursing/methods ; Extracorporeal Membrane Oxygenation/methods ; Female ; Humans ; Male ; Middle Aged
    Keywords covid19
    Language English
    Publishing date 2020-07-14
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 604632-0
    ISSN 1527-2966 ; 0099-1767
    ISSN (online) 1527-2966
    ISSN 0099-1767
    DOI 10.1016/j.jen.2020.07.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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