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  1. Article: [National pathology quality report in 2019].

    Lu, Z H / Chen, J

    Zhonghua bing li xue za zhi = Chinese journal of pathology

    2020  Volume 49, Issue 7, Page(s) 667–669

    MeSH term(s) China ; Pathology
    Language Chinese
    Publishing date 2020-06-26
    Publishing country China
    Document type Journal Article
    ZDB-ID 784533-9
    ISSN 0529-5807
    ISSN 0529-5807
    DOI 10.3760/cma.j.cn112151-20200331-00273
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Issues and reflections in the era of molecular classification for endometrial cancer].

    Yu, S N / Zong, L J / Chen, J / Lu, Z H

    Zhonghua bing li xue za zhi = Chinese journal of pathology

    2022  Volume 51, Issue 7, Page(s) 585–588

    MeSH term(s) Endometrial Neoplasms/genetics ; Endometrium ; Female ; Humans
    Language Chinese
    Publishing date 2022-07-04
    Publishing country China
    Document type Journal Article
    ZDB-ID 784533-9
    ISSN 0529-5807
    ISSN 0529-5807
    DOI 10.3760/cma.j.cn112151-20220309-00160
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [The application of predicted body weight equations for tidal volume setting in mechanical ventilation].

    Fan, S W / Lu, Z H / Liu, L

    Zhonghua nei ke za zhi

    2021  Volume 60, Issue 9, Page(s) 849–851

    MeSH term(s) Body Weight ; Humans ; Respiration, Artificial ; Respiratory Distress Syndrome ; Tidal Volume
    Language Chinese
    Publishing date 2021-08-23
    Publishing country China
    Document type Journal Article
    ZDB-ID 754223-9
    ISSN 0578-1426
    ISSN 0578-1426
    DOI 10.3760/cma.j.cn112138-20200924-00837
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Analytical value of histological research and application of RNAscope technology in liver diseases].

    Tang, H / Zhu, Y W / Lu, Z H

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2020  Volume 28, Issue 4, Page(s) 365–368

    Abstract: RNAscope is a new generation of in situ hybridization technology and with the advantage of new probe design, it is now being gradually applied to a wide range of research fields, and its research scope is constantly expanding. Our country has large ... ...

    Abstract RNAscope is a new generation of in situ hybridization technology and with the advantage of new probe design, it is now being gradually applied to a wide range of research fields, and its research scope is constantly expanding. Our country has large number of liver disease patients, so there is a great demand for histological testing and research evaluation based upon biological information. This technology has unique specificity and sensitivity in situ level, which makes up for the technical defects of immunohistochemistry and traditional in situ hybridization. Realizing the multiplicity and monomolecular level detection, the qualitative and quantitative analysis of nucleic acid level can be carried out in many aspects of the field of liver disease, and the visual evaluation can be achieved by combining it with tissue in situ to highlight the value of "gold standard". This article summarizes the recent year's application of RNAscope technology carried out in liver histology field.
    MeSH term(s) Humans ; Immunohistochemistry ; In Situ Hybridization ; Liver Diseases/diagnosis ; RNA/analysis ; Sensitivity and Specificity
    Chemical Substances RNA (63231-63-0)
    Language Chinese
    Publishing date 2020-05-04
    Publishing country China
    Document type Journal Article ; Review
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.cn501113-20191107-00409
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Clinicopathological analysis of lung metastatic tumor].

    Lou, N / Niu, Y R / Yang, F / Lu, Z H

    Zhonghua bing li xue za zhi = Chinese journal of pathology

    2021  Volume 50, Issue 9, Page(s) 1039–1044

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adolescent ; Adult ; Aged ; Biomarkers, Tumor ; Carcinoma, Transitional Cell ; Diagnosis, Differential ; Female ; Humans ; Immunohistochemistry ; Kidney Neoplasms ; Lung ; Lung Neoplasms/diagnosis ; Male ; Middle Aged ; Urinary Bladder Neoplasms ; Young Adult
    Chemical Substances Biomarkers, Tumor
    Language Chinese
    Publishing date 2021-09-08
    Publishing country China
    Document type Journal Article
    ZDB-ID 784533-9
    ISSN 0529-5807
    ISSN 0529-5807
    DOI 10.3760/cma.j.cn112151-20201229-00982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Clinical features and enzyme replacement therapy in 4 children with Fabry disease].

    Lu, Z H / Wang, J J / Yu, L / Mao, J H

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2021  Volume 59, Issue 4, Page(s) 322–326

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adolescent ; Age of Onset ; Child ; Enzyme Replacement Therapy ; Fabry Disease/drug therapy ; Fabry Disease/genetics ; Female ; Humans ; Male ; Retrospective Studies ; Treatment Outcome
    Language Chinese
    Publishing date 2021-03-27
    Publishing country China
    Document type Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.cn112140-20200902-00842
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Immune status of liver failure patients and related immune regulation therapy].

    Lu, Z H / Gan, J H

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2017  Volume 25, Issue 9, Page(s) 641–645

    Abstract: Liver failure refers to a series of clinical syndromes manifesting as coagulation disorders, jaundice, hepatic encephalopathy, ascites, and other decompensated abnormalities due to serious hepatic dysfunction or decompensation in terms of synthesis, ... ...

    Abstract Liver failure refers to a series of clinical syndromes manifesting as coagulation disorders, jaundice, hepatic encephalopathy, ascites, and other decompensated abnormalities due to serious hepatic dysfunction or decompensation in terms of synthesis, detoxification, excretion, and biological transformation caused by a variety of factors. In recent years, with the development of the research on immunological pathogenesis of liver failure, the "three-hit" theory clarifies the pathogenesis of liver failure. Major therapeutic strategies for liver failure are to prevent hepatocyte necrosis, promote hepatocyte regeneration, create a good internal environment for hepatocyte regeneration, and actively prevent and treat complications. An understanding of the immune status of liver failure patients and early application of glucocorticoids at right timing may help to improve prognosis and reduce adverse reactions. Establishment of a quantitative or functional balance between different cell subsets and new thoughts on some key cytokines may provide new directions and targets for immune regulation of liver failure.
    MeSH term(s) Ascites ; Cytokines/metabolism ; Hepatic Encephalopathy/immunology ; Hepatic Encephalopathy/pathology ; Humans ; Liver/immunology ; Liver/pathology ; Liver Diseases/immunology ; Liver Diseases/pathology ; Prognosis
    Chemical Substances Cytokines
    Language Chinese
    Publishing date 2017-11-06
    Publishing country China
    Document type Journal Article
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.issn.1007-3418.2017.09.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Progress on correlation between pathological features and prognosis of adult granulosa cell tumor of the ovary].

    Liu, Y L / Lyu, Z Y / Chen, J C / Yu, S N / Lu, Z H / Chen, J

    Zhonghua bing li xue za zhi = Chinese journal of pathology

    2023  Volume 52, Issue 6, Page(s) 657–660

    MeSH term(s) Adult ; Female ; Humans ; Granulosa Cell Tumor/surgery ; Granulosa Cell Tumor/pathology ; Prognosis ; Ovarian Neoplasms/surgery ; Ovarian Neoplasms/pathology
    Language Chinese
    Publishing date 2023-06-01
    Publishing country China
    Document type Journal Article
    ZDB-ID 784533-9
    ISSN 0529-5807
    ISSN 0529-5807
    DOI 10.3760/cma.j.cn112151-20230317-00207
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [A child of Fabry disease with appendicitis as initial symptom and family screening].

    Lu, Z H / Chen, J Y / Chen, B R / Xie, Y / Li, D Y / Zhang, L X / Jiang, M D / Mao, J H

    Zhonghua nei ke za zhi

    2023  Volume 62, Issue 10, Page(s) 1220–1222

    Language Chinese
    Publishing date 2023-09-27
    Publishing country China
    Document type Journal Article
    ZDB-ID 754223-9
    ISSN 0578-1426
    ISSN 0578-1426
    DOI 10.3760/cma.j.cn112138-20230112-00017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Comparison of the Physical Function Trajectories in Three Birth Cohorts of Chinese Older Adults: A 14-Year Longitudinal Study.

    Auyeung, T W / Leung, J C S / Lu, Z-H / Tsang, C / Lee, J S W / Kwok, T C Y / Woo, J

    The journal of nutrition, health & aging

    2023  Volume 27, Issue 11, Page(s) 1056–1062

    Abstract: Objectives: It remains uncertain whether the favorable trend of reduction in physical disabilities has become reversed in the recent-born cohorts of older adults. This study aimed to compare the rate of decline with time in self-reported Instrumental ... ...

    Abstract Objectives: It remains uncertain whether the favorable trend of reduction in physical disabilities has become reversed in the recent-born cohorts of older adults. This study aimed to compare the rate of decline with time in self-reported Instrumental Activity of Daily Living (IADL) difficulties, objective measurement of gait speed and grip strength, in three birth cohorts of Chinese older adults.
    Design: A prospective cohort study.
    Setting and participants: Four thousand Chinese older adults aged 65 years or above in three birth cohorts (1934-1938, 1929-1933, 1905-1928) were recruited from the community in Hong Kong.
    Measurements: Grip strength, gait speed and IADL difficulties were measured between 2001 to 2017. Joint models were used to examine the trajectories of grip strength, gait speed and IADL difficulties over time, and the interaction effect of age-by-cohort (or also age2-by-cohort) was also examined.
    Results: The recently born cohort (1934 - 1938) had worse grip strength and more IADL difficulties at the same age than the earlier two cohorts (1929 - 1933; 1905 - 1928). Furthermore, the most recently born cohort also followed a more rapid decline longitudinally with a greater decline observed in gait speed, grip strength and IADL difficulties for women whereas a greater decline in grip strength and IADL difficulties for men.
    Conclusions: The continuous improvement of physical limitations in old age may have halted and there appears to be a reversal of this favourable trend in the recent born cohort of older adults living in Hong Kong.
    MeSH term(s) Aged ; Female ; Humans ; Male ; Activities of Daily Living ; Birth Cohort ; East Asian People ; Hand Strength ; Longitudinal Studies ; Prospective Studies ; Physical Functional Performance
    Language English
    Publishing date 2023-10-05
    Publishing country France
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2081921-3
    ISSN 1760-4788 ; 1279-7707
    ISSN (online) 1760-4788
    ISSN 1279-7707
    DOI 10.1007/s12603-023-2026-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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