LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 15

Search options

  1. Article ; Online: Advances in Diagnosis and Treatment of Gynecological Malignancies

    Luca Roncati

    Journal of Clinical Medicine, Vol 11, Iss 3797, p

    A Special Issue in Line with 2030 Agenda

    2022  Volume 3797

    Abstract: Among the 17 Sustainable Development Goals (SDG) of the United Nations 2030 Agenda, “good health and well-being” is point number 3 (SDG3), and all our efforts must be calibrated in this direction worldwide [.] ...

    Abstract Among the 17 Sustainable Development Goals (SDG) of the United Nations 2030 Agenda, “good health and well-being” is point number 3 (SDG3), and all our efforts must be calibrated in this direction worldwide [.]
    Keywords n/a ; Medicine ; R
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Nanoparticles and pregnancy

    Luca Roncati

    Clinical and Experimental Obstetrics & Gynecology, Vol 49, Iss 5, p

    from benchside to the community

    2022  Volume 104

    Keywords pregnancy ; nanoparticles ; iron oxide nanoparticles ; silver nanoparticles ; copper nanoparticles ; cerium dioxide nanoparticles ; titanium dioxide nanoparticles ; carbon nanotubes ; translational medicine ; Gynecology and obstetrics ; RG1-991
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher IMR Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Editorial

    Luca Roncati / Qun Treen Huo

    Frontiers in Medicine, Vol

    Post COVID-19: the nucleoside-modified messenger RNA (modRNA) platform

    2024  Volume 10

    Keywords Coronavirus Disease 2019 (COVID-19) vaccine ; messenger RNA (mRNA) ; nucleoside-modified mRNA (modRNA) ; nanoparticles ; dendritic cells ; personalized oncology ; Medicine (General) ; R5-920
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Sudden infant death syndrome

    Luca Roncati / Francesco Piscioli

    Italian Journal of Medicine, Vol 17, Iss

    revealing this mystery is possible

    2023  Volume 3

    Abstract: Dear Editor, The sudden and unexpected loss of an infant in the first months of life is a heartbreaking and devastating experience for any parent. Understandably, it can be an extremely distressing time for the mother, who may often find herself unfairly ...

    Abstract Dear Editor, The sudden and unexpected loss of an infant in the first months of life is a heartbreaking and devastating experience for any parent. Understandably, it can be an extremely distressing time for the mother, who may often find herself unfairly burdened with guilt. When this tragic event occurs, a thorough investigation becomes necessary to determine the cause of death and also absolve the mother of any responsibility. [.]
    Keywords Medicine ; R
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher PAGEPress Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Trends in the COVID-19 Pandemic in Italy during the Summers of 2020 (before Mass Vaccination), 2021 (after Primary Mass Vaccination) and 2022 (after Booster Mass Vaccination)

    Luca Roncati / Giulia Bartolacelli / Carlo Galeazzi / Stefania Caramaschi

    Pathogens, Vol 12, Iss 12, p

    A Real-World Nationwide Study Based on a Population of 58.85 Million People

    2023  Volume 1376

    Abstract: Like all RNA viruses, SARS-CoV-2 shows a high mutation rate, which has led to the emergence of new variants. Among them, Gamma and Delta developed at the turn of 2020–2021 in Amazonas and India, two ecoregions characterized by hot-humid weather, very ... ...

    Abstract Like all RNA viruses, SARS-CoV-2 shows a high mutation rate, which has led to the emergence of new variants. Among them, Gamma and Delta developed at the turn of 2020–2021 in Amazonas and India, two ecoregions characterized by hot-humid weather, very similar to that of the summer season in Italy due to climate change, the first Western country to be hit hard by COVID-19 and to experience lockdown restrictions in a democratic framework of 58.85 million people. The aim of our research has been to evaluate the impact of climate on the COVID-19 pandemic in Italy during the summers of 2020 (before mass vaccination), 2021 (after primary mass vaccination) and 2022 (after booster mass vaccination), also taking into account the emergence of these two variants. Methods: During the state of national health emergency and the Draghi government, the Civil Defense Department released the aggregate data coming from the Ministry of Health, the Higher Institute of Health, the Independent Provinces and the Italian Regions daily, in order to inform about the pandemic situation in Italy. Among these data there were the number of deaths, hospitalizations in intensive care units (ICU), non-ICU patients, contagions and performed swabs. By means of a team effort, we have collected and elaborated all these data, comparing the COVID-19 pandemic in Italy during the summers of 2020 (following the nationwide lockdown), 2021 and 2022. Results: from the summer of 2020 to the summers of 2021 and 2022 all pandemic trend indicators have shown a sharp worsening in Italy. COVID-19 deaths increased by ≈298% and ≈834%, ICU hospitalizations by ≈386% and ≈310%, non-ICU hospitalizations by ≈224% and ≈600%, contagions by ≈627% and ≈6850% (i.e., ≈68.50 times), swabs by ≈354% and ≈370%, and the mean positivity rate passed from ≈1% to ≈2% and ≈20%, respectively. Conclusions: SARS-CoV-2 can be transmitted in any climate, including areas with hot and humid weather, and the emergence of variants adapted to hot-humid climates may result in summer COVID-19 ...
    Keywords COVID-19 ; SARS-CoV-2 ; SARS-CoV-2 Gamma variant ; SARS-CoV-2 Delta variant ; variant of concern (VOC) ; tropical and subtropical moist broadleaf forests (TSMF) ; Medicine ; R
    Subject code 940
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Diagnostic, Prognostic and Predictive Immunohistochemistry in Malignant Melanoma of the Skin.

    Luca, Roncati

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

    2018  Volume 31, Issue 2, Page(s) 152–155

    Title translation Diagnostická, prognostická a prediktivní imunohistochemie při maligním melanomu kůže.
    MeSH term(s) Biomarkers, Tumor/metabolism ; Humans ; Immunohistochemistry ; Melanoma/diagnosis ; Melanoma/metabolism ; Prognosis ; Skin Neoplasms/diagnosis ; Skin Neoplasms/metabolism ; Melanoma, Cutaneous Malignant
    Chemical Substances Biomarkers, Tumor
    Language English
    Publishing date 2018-04-15
    Publishing country Czech Republic
    Document type Journal Article
    ZDB-ID 1217739-8
    ISSN 0862-495X
    ISSN 0862-495X
    DOI 10.14735/amko2018152
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4181: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: A Three-Case Series of Thrombotic Deaths in Patients over 50 with Comorbidities Temporally after modRNA COVID-19 Vaccination

    Luca Roncati / Antonio Manenti / Lorenzo Corsi

    Pathogens, Vol 11, Iss 435, p

    2022  Volume 435

    Abstract: Coronavirus disease 2019 (COVID-19) is the most dramatic pandemic of the new millennium; to counteract it, specific vaccines have been launched in record time under emergency use authorization or conditional marketing authorization by virtue of a ... ...

    Abstract Coronavirus disease 2019 (COVID-19) is the most dramatic pandemic of the new millennium; to counteract it, specific vaccines have been launched in record time under emergency use authorization or conditional marketing authorization by virtue of a favorable risk/benefit balance. Among the various technological platforms, there is that exploiting a nucleoside-modified messenger RNA (modRNA), such as Comirnaty ® , and that which is adenoviral vector-based. In the ongoing pharmacovigilance, the product information of the latter has been updated about the risk of thrombotic thrombocytopenia, venous thromboembolism without thrombocytopenia and immune thrombocytopenia without thrombosis. However, from an in-depth literature review, the same adverse events can rarely occur with modRNA vaccines too. In support of this, we here report a three-case series of thrombotic deaths in patients over 50 with comorbidities temporally after Comirnaty ® , investigated by means of post-mortem histopathology and immunohistochemistry. In two out of three cases, the cause of death is traced back to pulmonary microthromboses rich in activated platelets, quite similar morphologically to those described in patients who died from severe COVID-19. Even if remote in the face of millions of administered doses, clinicians should be aware of the possible thrombotic risk also after Comirnaty ® , in order to avoid a misdiagnosis with potentially lethal consequences. Since COVID-19 vaccines are inoculated in subjects to be protected, maximum attention must be paid to their safety, and prophylactic measures to increase it are always welcome. In light of the evidence, the product information of modRNA COVID-19 vaccines should be updated about the thrombotic risk, as happened for adenoviral vector-based vaccines.
    Keywords coronavirus disease 2019 (COVID-19) ; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ; nucleoside-modified messenger RNA (modRNA) ; Comirnaty ® ; Pfizer/BioNTech COVID-19 Vaccine ; autopsy ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: A histogenetic view inside the ICD-O A Histogenetic View of the International Classification of Diseases for Oncology Melanomas

    Luca Roncati / Francesco Piscioli

    Erciyes Medical Journal, Vol 41, Iss 2, Pp 221-

    2019  Volume 222

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2019-05-01T00:00:00Z
    Publisher KARE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Cubital Tunnel Syndrome Temporally after COVID-19 Vaccination

    Luca Roncati / Davide Gravina / Caterina Marra / Norman Della Rosa / Roberto Adani

    Tropical Medicine and Infectious Disease, Vol 7, Iss 62, p

    2022  Volume 62

    Abstract: Coronavirus disease 2019 (COVID-19) is the most dramatic pandemic of the new millennium. To counter it, specific vaccines have been launched in record time under emergency use authorization or conditional marketing authorization and have been subjected ... ...

    Abstract Coronavirus disease 2019 (COVID-19) is the most dramatic pandemic of the new millennium. To counter it, specific vaccines have been launched in record time under emergency use authorization or conditional marketing authorization and have been subjected to additional monitoring. The European Medicines Agency recommend reporting any suspected adverse reactions during this additional monitoring phase. For the first time in the available medical literature, we report a left cubital tunnel syndrome in a 28-year-old right-handed healthy male after seven days from the first dose of Spikevax ® (formerly Moderna COVID-19 Vaccine). Histochemistry for Alcian Blue performed on the tissue harvested from the cubital site reveals myxoid degeneration of the small nerve collaterals, a clear sign of nerve injury. It still remains unclear why the syndrome occurs in a localized and not generalized form to all osteofibrous tunnels. Today, modified messenger ribonucleic acid vaccines as Spikevax ® represent an avantgarde technological platform with a lot of potential, but one which needs careful monitoring in order to identify in advance those patients who may experience adverse events after their administration.
    Keywords coronavirus disease 2019 (COVID-19) ; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ; vaccines ; modified messenger ribonucleic acid (modRNA) ; Spikevax ® ; modRNA COVID-19 vaccine ; Medicine ; R
    Subject code 333
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Possible Association Between DHEA and PKCε in Hepatic Encephalopathy Amelioration

    Alessandro Di Cerbo / Luca Roncati / Carlotta Marini / Gianluca Carnevale / Manuela Zavatti / Rossella Avallone / Lorenzo Corsi

    Frontiers in Veterinary Science, Vol

    A Pilot Study

    2021  Volume 8

    Abstract: Objective: Hepatic encephalopathy (HE) is a neuropsychiatric syndrome caused by liver failure and by an impaired neurotransmission and neurological function caused by hyperammonemia (HA). HE, in turn, decreases the phosphorylation of protein kinase C ... ...

    Abstract Objective: Hepatic encephalopathy (HE) is a neuropsychiatric syndrome caused by liver failure and by an impaired neurotransmission and neurological function caused by hyperammonemia (HA). HE, in turn, decreases the phosphorylation of protein kinase C epsilon (PKCε), contributing to the impairment of neuronal functions. Dehydroepiandrosterone (DHEA) exerts a neuroprotective effect by increasing the GABAergic tone through GABAA receptor stimulation. Therefore, we investigated the protective effect of DHEA in an animal model of HE, and the possible modulation of PKCε expression in different brain area.Methods: Fulminant hepatic failure was induced in 18 male, Sprague–Dawley rats by i.p. administration of 3 g/kg D-galactosamine, and after 30 min, a group of animals received a subcutaneous injection of 25 mg/kg (DHEA) repeated twice a day (3 days). Exploratory behavior and general activity were evaluated 24 h and 48 h after the treatments by the open field test. Then, brain cortex and cerebellum were used for immunoblotting analysis of PKCε level.Results: DHEA administration showed a significant improvement of locomotor activity both 24 and 48 h after D-galactosamine treatment (****p < 0.0001) but did not ameliorate liver parenchymal degeneration. Western blot analysis revealed a reduced immunoreactivity of PKCε (*p < 0.05) following D-galactosamine treatment in rat cortex and cerebellum. After the addition of DHEA, PKCε increased in the cortex in comparison with the D-galactosamine-treated (***p < 0.001) and control group (*p < 0.05), but decreased in the cerebellum (*p < 0.05) with respect to the control group. PKCε decreased after treatment with NH4Cl alone and in combination with DHEA in both cerebellum and cortex (****p < 0.0001). MTS assay demonstrated the synergistic neurotoxic action of NH4Cl and glutamate pretreatment in cerebellum and cortex along with an increased cell survival after DHEA pretreatment, which was significant only in the cerebellum (*p < 0.05).Conclusion: An association ...
    Keywords hepatic encephalopathy ; hyperammonemia ; protein kinase C (PKC) ; DHEA ; animal model ; Veterinary medicine ; SF600-1100
    Subject code 616 ; 630
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top